Toward homogeneous erythropoietin: Chemical synthesis of the Ala 1-Gly 28 glycopeptide domain by "Alanine" ligation

Journal of the American Chemical Society

Volumn 131, Issue 15, 2009, Pages 5438-5443

  Kan, Cindy ^a   Trzupek, John D ^a   Wu, Bin ^a   Wan, Qian ^a   Chen, Gong ^a   Tan, Zhongping ^a   Yuan, Yu ^a   Danishefsky, Samuel J ^a,b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID PEPTIDES; CHEMICAL SYNTHESIS; DIRECT COUPLING; FUNCTIONALIZATION; GLYCOFORM; GLYCOPEPTIDE; N-LINKED; N-TERMINAL; NATIVE CHEMICAL LIGATION; THIOESTER;

AMINES; AMINO ACIDS; DESULFURIZATION; ORGANIC ACIDS;

SYNTHESIS (CHEMICAL);

ALANINE; CARBOHYDRATE; CARBOXY TERMINAL TELOPEPTIDE; CYSTEINE; ERYTHROPOIETIN; GLYCINE; GLYCOPEPTIDE; NITROGEN; PEPTIDE FRAGMENT; THIOESTER; POLYSACCHARIDE;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHEMICAL PROCEDURES; DESULFURIZATION; PROTEIN DOMAIN; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; CHEMISTRY; GLYCOSYLATION; PROTEIN TERTIARY STRUCTURE; SYNTHESIS;

ALANINE; ERYTHROPOIETIN; GLYCOPEPTIDES; GLYCOSYLATION; PEPTIDE FRAGMENTS; POLYSACCHARIDES; PROTEIN STRUCTURE, TERTIARY;

EID: 67849097425     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja808707w     Document Type: Article

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