Transplantation of bone marrow mononuclear cells decreases seizure incidence, mitigates neuronal loss and modulates pro-inflammatory cytokine production in epileptic rats

Neurobiology of Disease

Volumn 46, Issue 2, 2012, Pages 302-313

  Costa Ferro, Zaquer S M ^a,b   Souza, Bruno S F ^b,c   Leal, Marcos M T ^b   Kaneto, Carla Martins ^b   Azevedo, Carine Machado ^b   da Silva, Igor Campos ^b   Soares, Milena B P ^b,c   Ribeiro dos Santos, Ricardo ^b   DaCosta, Jaderson C ^a  

^a PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b HOSPITAL SÃO RAFAEL   (Brazil)

^c INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

Bone marrow mononuclear cells; Cytokines; Neuronal loss; Pilocarpine; Seizure frequency; Temporal lobe epilepsy

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; PILOCARPINE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BONE MARROW MONONUCLEAR CELL TRANSPLANTATION; BONE MARROW TRANSPLANTATION; CELL PROLIFERATION; CELL THERAPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE DURATION; EPILEPSY; GLIOSIS; MALE; MORBIDITY; NERVE CELL DEGENERATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; RECURRENT DISEASE; RISK REDUCTION; SEIZURE;

ANIMALS; BONE MARROW TRANSPLANTATION; CELL MOVEMENT; CYTOKINES; EPILEPSY; INCIDENCE; INFLAMMATION MEDIATORS; LEUKOCYTES, MONONUCLEAR; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURONS; RATS; RATS, WISTAR;

EID: 84859508331     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2011.12.001     Document Type: Article

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