-
1
-
-
64949085560
-
Therapeutic antibodies: Current state and future trends-is a paradigm change coming soon
-
xiii
-
Dimitrov DS and Marks JD: Therapeutic antibodies: Current state and future trends-is a paradigm change coming soon? Methods Mol Biol 2009;525:1-27, xiii.
-
(2009)
Methods Mol. Biol.
, vol.525
, pp. 1-27
-
-
Dimitrov, D.S.1
Marks, J.D.2
-
2
-
-
0037456827
-
Antibody neutralization and escape by HIV-1
-
DOI 10.1038/nature01470
-
Wei X, Decker JM, Wang S, et al.: Antibody neutralization and escape by HIV-1. Nature 2003;422:307-312. (Pubitemid 36378357)
-
(2003)
Nature
, vol.422
, Issue.6929
, pp. 307-312
-
-
Wei, X.1
Decker, J.M.2
Wang, S.3
Hui, H.4
Kappes, J.C.5
Wu, X.6
Salazar-Gonzalez, J.F.7
Salazar, M.G.8
Kilby, J.M.9
Saag, M.S.10
Komarova, N.L.11
Nowak, M.A.12
Hahn, B.H.13
Kwong, P.D.14
Shaw, G.M.15
-
3
-
-
8644251891
-
Comprehensive cross-clade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodies
-
DOI 10.1128/JVI.78.23.13232-13252.2004
-
Binley JM, Wrin T, Korber B, et al.: Comprehensive crossclade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodies. J Virol 2004;78:13232-13252. (Pubitemid 39507829)
-
(2004)
Journal of Virology
, vol.78
, Issue.23
, pp. 13232-13252
-
-
Binley, J.M.1
Wrin, T.2
Korber, B.3
Zwick, M.B.4
Wang, M.5
Chappey, C.6
Stiegler, G.7
Kunert, R.8
Zolla-Pazner, S.9
Katinger, H.10
Petropoulos, C.J.11
Burton, D.R.12
-
4
-
-
65549146370
-
Human monoclonal antibodies and engineered antibody domains as HIV-1 entry inhibitors
-
Chen W and Dimitrov DS: Human monoclonal antibodies and engineered antibody domains as HIV-1 entry inhibitors. Curr Opin HIV AIDS 2009;4:112-117.
-
(2009)
Curr. Opin. HIV AIDS
, vol.4
, pp. 112-117
-
-
Chen, W.1
Dimitrov, D.S.2
-
5
-
-
70349887757
-
Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target
-
Walker LM, Phogat SK, Chan-Hui PY, et al.: Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target. Science 2009;326:285-289.
-
(2009)
Science
, vol.326
, pp. 285-289
-
-
Walker, L.M.1
Phogat, S.K.2
Chan-Hui, P.Y.3
-
6
-
-
77649318846
-
Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals
-
Corti D, Langedijk JP, Hinz A, et al.: Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals. PLoS ONE 2010;5:e8805.
-
(2010)
PLoS ONE
, vol.5
-
-
Corti, D.1
Langedijk, J.P.2
Hinz, A.3
-
7
-
-
77954920017
-
Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1
-
Wu X, Yang ZY, Li Y, et al.: Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1. Science 2010;329:856-861.
-
(2010)
Science
, vol.329
, pp. 856-861
-
-
Wu, X.1
Yang, Z.Y.2
Li, Y.3
-
8
-
-
55949131238
-
Human domain antibodies to conserved sterically restricted regions on gp120 as exceptionally potent cross-reactive HIV-1 neutralizers
-
Chen W, Zhu Z, Feng Y, and Dimitrov DS: Human domain antibodies to conserved sterically restricted regions on gp120 as exceptionally potent cross-reactive HIV-1 neutralizers. Proc Natl Acad Sci USA 2008;105:17121-17126.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 17121-17126
-
-
Chen, W.1
Zhu, Z.2
Feng, Y.3
Dimitrov, D.S.4
-
9
-
-
0032543307
-
Structure of an HIV gp 120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
-
DOI 10.1038/31405
-
Kwong PD, Wyatt R, Robinson J, Sweet RW, Sodroski J, and Hendrickson WA: Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature 1998;393:648-659. (Pubitemid 28289647)
-
(1998)
Nature
, vol.393
, Issue.6686
, pp. 648-659
-
-
Kwong, P.D.1
Wyatt, R.2
Robinson, J.3
Sweet, R.W.4
Sodroski, J.5
Hendrickson, W.A.6
-
11
-
-
0028291731
-
Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1
-
Roben P, Moore JP, Thali M, Sodroski J, Barbas CF, 3rd, and Burton DR: Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1. J Virol 1994;68: 4821-4828. (Pubitemid 24226546)
-
(1994)
Journal of Virology
, vol.68
, Issue.8
, pp. 4821-4828
-
-
Roben, P.1
Moore, J.P.2
Thali, M.3
Sodroski, J.4
Barbas III, C.F.5
Burton, D.R.6
-
12
-
-
70450182950
-
Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120
-
Chen L, Kwon YD, Zhou T, et al.: Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120. Science 2009;326:1123-1127.
-
(2009)
Science
, vol.326
, pp. 1123-1127
-
-
Chen, L.1
Kwon, Y.D.2
Zhou, T.3
-
13
-
-
4143088167
-
Identification and characterization of a new cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody
-
DOI 10.1128/JVI.78.17.9233-9242.2004
-
Zhang MY, Xiao X, Sidorov IA, et al.: Identification and characterization of a new cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody. J Virol 2004;78:9233-9242. (Pubitemid 39096533)
-
(2004)
Journal of Virology
, vol.78
, Issue.17
, pp. 9233-9242
-
-
Zhang, M.-Y.1
Xiao, X.2
Sidorov, I.A.3
Choudhry, V.4
Cham, F.5
Zhang, P.F.6
Bouma, P.7
Zwick, M.8
Choudhary, A.9
Montefiori, D.C.10
Broder, C.C.11
Burton, D.R.12
Quinnan Jr., G.V.13
Dimitrov, D.S.14
-
14
-
-
10744226328
-
Broadly cross-reactive HIV neutralizing human monoclonal antibody Fab selected by sequential antigen panning of a phage display library
-
DOI 10.1016/j.jim.2003.07.003
-
Zhang MY, Shu Y, Phogat S, et al.: Broadly cross-reactive HIV neutralizing human monoclonal antibody Fab selected by sequential antigen panning of a phage display library. J Immunol Methods 2003;283:17-25. (Pubitemid 37501056)
-
(2003)
Journal of Immunological Methods
, vol.283
, Issue.1-2
, pp. 17-25
-
-
Zhang, M.-Y.1
Shu, Y.2
Phogat, S.3
Xiao, X.4
Cham, F.5
Bouma, P.6
Choudhary, A.7
Feng, Y.-R.8
Sanz, I.9
Rybak, S.10
Broder, C.C.11
Quinnan Jr., G.V.12
Evans, T.13
Dimitrov, D.S.14
-
15
-
-
0029058337
-
Protection against HIV-1 infection in hu-PBL-SCID mice by passive immunization with a neutralizing human monoclonal antibody against the gp120 CD4-binding site
-
Parren PW, Ditzel HJ, Gulizia RJ, et al.: Protection against HIV-1 infection in hu-PBL-SCID mice by passive immunization with a neutralizing human monoclonal antibody against the gp120 CD4-binding site. AIDS 1995; 9:F1-6.
-
(1995)
AIDS
, vol.9
-
-
Parren, P.W.1
Ditzel, H.J.2
Gulizia, R.J.3
-
16
-
-
0034864776
-
Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro
-
DOI 10.1128/JVI.75.17.8340-8347.2001
-
Parren PW, Marx PA, Hessell AJ, et al.: Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro. J Virol 2001;75:8340-8347. (Pubitemid 32743706)
-
(2001)
Journal of Virology
, vol.75
, Issue.17
, pp. 8340-8347
-
-
Parren, P.W.H.I.1
Marx, P.A.2
Hessell, A.J.3
Luckay, A.4
Harouse, J.5
Cheng-Mayer, C.6
Moore, J.P.7
Burton, D.R.8
-
17
-
-
0345471066
-
Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120
-
DOI 10.1038/nm833
-
Veazey RS, Shattock RJ, Pope M, et al.: Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120. Nat Med 2003;9:343-346. (Pubitemid 36362791)
-
(2003)
Nature Medicine
, vol.9
, Issue.3
, pp. 343-346
-
-
Veazey, R.S.1
Shattock, R.J.2
Pope, M.3
Kirijan, J.C.4
Jones, J.5
Hu, Q.6
Ketas, T.7
Marx, P.A.8
Klasse, P.J.9
Burton, D.R.10
Moore, J.P.11
-
18
-
-
34548496893
-
Fc receptor but not complement binding is important in antibody protection against HIV
-
DOI 10.1038/nature06106, PII NATURE06106
-
Hessell AJ, Hangartner L, Hunter M, et al.: Fc receptor but not complement binding is important in antibody protection against HIV. Nature 2007;449:101-104. (Pubitemid 47373775)
-
(2007)
Nature
, vol.449
, Issue.7158
, pp. 101-104
-
-
Hessell, A.J.1
Hangartner, L.2
Hunter, M.3
Havenith, C.E.G.4
Beurskens, F.J.5
Bakker, J.M.6
Lanigan, C.M.S.7
Landucci, G.8
Forthal, D.N.9
Parren, P.W.H.I.10
Marx, P.A.11
Burton, D.R.12
-
19
-
-
0032080680
-
Phase I study of a human monoclonal antibody directed against the CD4- binding site of HIV type 1 glycoprotein 120
-
Cavacini LA, Samore MH, Gambertoglio J, et al.: Phase I study of a human monoclonal antibody directed against the CD4-binding site of HIV type 1 glycoprotein 120. AIDS Res Hum Retroviruses 1998;14:545-550. (Pubitemid 28196781)
-
(1998)
AIDS Research and Human Retroviruses
, vol.14
, Issue.7
, pp. 545-550
-
-
Cavacini, L.A.1
Samore, M.H.2
Gambertoglio, J.3
Jackson, B.4
Duval, M.5
Wisnewski, A.6
Hammer, S.7
Koziel, C.8
Trapnell, C.9
Posner, M.R.10
-
20
-
-
84860492563
-
VRC01 provides sterilizing protection to non human primates from mucosal SHIV challenges
-
Pegu A, Yang Z, Chen X, et al.: VRC01 provides sterilizing protection to non human primates from mucosal SHIV challenges. J Immunol 2011;186:155.11.
-
(2011)
J. Immunol.
, vol.186
, pp. 15511
-
-
Pegu, A.1
Yang, Z.2
Chen, X.3
-
21
-
-
0028155283
-
Generation of human monoclonal antibodies against HIV-1 proteins: Electrofusion and Epstein-Barr virus transformation for peripheral blood lymphocyte immortalization
-
Buchacher A, Predl R, Strutzenberger K, et al.: Generation of human monoclonal antibodies against HIV-1 proteins; electrofusion and Epstein-Barr virus transformation for peripheral blood lymphocyte immortalization. AIDS Res Hum Retroviruses 1994;10:359-369. (Pubitemid 24141210)
-
(1994)
AIDS Research and Human Retroviruses
, vol.10
, Issue.4
, pp. 359-369
-
-
Buchacher, A.1
Predl, R.2
Strutzenberger, K.3
Steinfellner, W.4
Trkola, A.5
Purtscher, M.6
Gruber, G.7
Tauer, C.8
Steindl, F.9
Jungbauer, A.10
Katinger, H.11
-
22
-
-
9044241681
-
Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1
-
Trkola A, Purtscher M, Muster T, et al.: Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1. J Virol 1996;70:1100-1108. (Pubitemid 26029030)
-
(1996)
Journal of Virology
, vol.70
, Issue.2
, pp. 1100-1108
-
-
Trkola, A.1
Purtscher, M.2
Muster, T.3
Ballaun, C.4
Buchacher, A.5
Sullivan, N.6
Srinivasan, K.7
Sodroski, J.8
Moore, J.P.9
Katinger, H.10
-
23
-
-
0032947286
-
Protection of macaques against pathogenic simian/human immunodeficiency virus 89.6PD by passive transfer of neutralizing antibodies
-
Mascola JR, Lewis MG, Stiegler G, et al.: Protection of macaques against pathogenic simian/human immunodeficiency virus 89.6PD by passive transfer of neutralizing antibodies. J Virol 1999;73:4009-4018. (Pubitemid 29189846)
-
(1999)
Journal of Virology
, vol.73
, Issue.5
, pp. 4009-4018
-
-
Mascola, J.R.1
Lewis, M.G.2
Stiegler, G.3
Harris, D.4
Vancott, T.C.5
Hayes, D.6
Louder, M.K.7
Brown, C.R.8
Sapan, C.V.9
Frankel, S.S.10
Lu, Y.11
Robb, M.L.12
Katinger, H.13
Birx, D.L.14
-
24
-
-
0033951746
-
Protection of macaques against vaginal transmission of a pathogenic HIV- 1/SIV chimeric virus by passive infusion of neutralizing antibodies
-
DOI 10.1038/72318
-
Mascola JR, Stiegler G, VanCott TC, et al.: Protection of macaques against vaginal transmission of a pathogenic HIV- 1/SIV chimeric virus by passive infusion of neutralizing antibodies. Nat Med 2000;6:207-210. (Pubitemid 30082367)
-
(2000)
Nature Medicine
, vol.6
, Issue.2
, pp. 207-210
-
-
Mascola, J.R.1
Stiegler, G.2
Vancott, T.C.3
Katinger, H.4
Carpenter, C.B.5
Hanson, C.E.6
Beary, H.7
Hayes, D.8
Frankel, S.S.9
Birx, D.L.10
Lewis, M.G.11
-
25
-
-
67249131966
-
Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers
-
Hessell AJ, Rakasz EG, Poignard P, et al.: Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers. PLoS Pathog 2009;5:e1000433.
-
(2009)
PLoS Pathog.
, vol.5
-
-
Hessell, A.J.1
Rakasz, E.G.2
Poignard, P.3
-
26
-
-
0030612105
-
Synergistic neutralization of a chimetic SIV/HIV type 1 virus with combinations of human anti-HIV type 1 envelope monoclonal antibodies or hyperimmune globulins
-
Li A, Baba TW, Sodroski J, et al.: Synergistic neutralization of a chimeric SIV/HIV type 1 virus with combinations of human anti-HIV type 1 envelope monoclonal antibodies or hyperimmune globulins. AIDS Res Hum Retroviruses 1997;13:647-656. (Pubitemid 27210453)
-
(1997)
AIDS Research and Human Retroviruses
, vol.13
, Issue.8
, pp. 647-656
-
-
Li, A.N.1
Baba, T.W.2
Sodroski, J.3
Zolla-Pazner, S.4
Gorny, M.K.5
Robinson, J.6
Posner, M.R.7
Katinger, H.8
Barbas III, C.F.9
Burton, D.R.10
Chou, T.-C.11
Ruprecht, R.M.12
-
27
-
-
0031897793
-
+ by triple and quadruple combinations of human monoclonal antibodies and high-titer anti-human immunodeficiency virus type 1 immunoglobulins
-
Li A, Katinger H, Posner MR, et al.: Synergistic neutralization of simian-human immunodeficiency virus SHIV-vpu + by triple and quadruple combinations of human monoclonalantibodies and high-titer anti-human immunodeficiency virus type 1 immunoglobulins. J Virol 1998;72:3235-3240. (Pubitemid 28175568)
-
(1998)
Journal of Virology
, vol.72
, Issue.4
, pp. 3235-3240
-
-
Li, A.1
Katinger, H.2
Posner, M.R.3
Cavacini, L.4
Zolla-Pazner, S.5
Gorny, M.K.6
Sodroski, J.7
Chou, T.-C.8
Baba, T.W.9
Ruprecht, R.M.10
-
28
-
-
69249220320
-
A conformational switch in human immunodeficiency virus gp41 revealed by the structures of overlapping epitopes recognized by neutralizing antibodies
-
Pejchal R, Gach JS, Brunel FM, et al.: A conformational switch in human immunodeficiency virus gp41 revealed by the structures of overlapping epitopes recognized by neutralizing antibodies. J Virol 2009;83:8451-8462.
-
(2009)
J. Virol.
, vol.83
, pp. 8451-8462
-
-
Pejchal, R.1
Gach, J.S.2
Brunel, F.M.3
-
29
-
-
33947635198
-
The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes
-
Alam SM, McAdams M, Boren D, et al.: The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes. J Immunol 2007;178: 4424-4435. (Pubitemid 46492394)
-
(2007)
Journal of Immunology
, vol.178
, Issue.7
, pp. 4424-4435
-
-
Alam, S.M.1
McAdams, M.2
Boren, D.3
Rak, M.4
Scearce, R.M.5
Gao, F.6
Camacho, Z.T.7
Gewirth, D.8
Kelsoe, G.9
Chen, P.10
Haynes, B.F.11
-
30
-
-
34247106331
-
An affinity-enhanced neutralizing antibody against the membrane-proximal external region of human immunodeficiency virus type 1 gp41 recognizes an epitope between those of 2F5 and 4E10
-
DOI 10.1128/JVI.02588-06
-
Nelson JD, Brunel FM, Jensen R, et al.: An affinity-enhanced neutralizing antibody against the membrane-proximal external region of human immunodeficiency virus type 1 gp41 recognizes an epitope between those of 2F5 and 4E10. J Virol 2007;81:4033-4043. (Pubitemid 46586898)
-
(2007)
Journal of Virology
, vol.81
, Issue.8
, pp. 4033-4043
-
-
Nelson, J.D.1
Brunel, F.M.2
Jensen, R.3
Crooks, E.T.4
Cardoso, R.M.F.5
Wang, M.6
Hessell, A.7
Wilson, I.A.8
Binley, J.M.9
Dawson, P.E.10
Burton, D.R.11
Zwick, M.B.12
-
31
-
-
80055115557
-
Cross-reactive HIV-1- neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies
-
in press
-
Zhu Z, Qin HR, Chen W, et al.: Cross-reactive HIV-1- neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies. J Virol 2011, in press.
-
(2011)
J. Virol.
-
-
Zhu, Z.1
Qin, H.R.2
Chen, W.3
-
32
-
-
0037169214
-
A phase I trial with two human monoclonal antibodies (hMAb 2F5, 2G12) against HIV-1
-
DOI 10.1097/00002030-200201250-00012
-
Armbruster C, Stiegler GM, Vcelar BA, et al.: A phase I trial with two human monoclonal antibodies (hMAb 2F5, 2G12) against HIV-1. AIDS 2002;16:227-233. (Pubitemid 34118570)
-
(2002)
AIDS
, vol.16
, Issue.2
, pp. 227-233
-
-
Armbruster, C.1
Stiegler, G.M.2
Vcelar, B.A.3
Jager, W.4
Michael, N.L.5
Vetter, N.6
Katinger, H.W.D.7
-
33
-
-
0037708018
-
Antibody protection: Passive immunization of neonates against oral AIDS virus challenge
-
DOI 10.1016/S0264-410X(03)00335-9
-
Ruprecht RM, Ferrantelli F, Kitabwalla M, Xu W, and McClure HM: Antibody protection: Passive immunization of neonates against oral AIDS virus challenge. Vaccine 2003;21: 3370-3373. (Pubitemid 36792088)
-
(2003)
Vaccine
, vol.21
, Issue.24
, pp. 3370-3373
-
-
Ruprecht, R.M.1
Ferrantelli, F.2
Kitabwalla, M.3
Xu, W.4
McClure, H.M.5
-
34
-
-
0033952103
-
Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection
-
DOI 10.1038/72309
-
Baba TW, Liska V, Hofmann-Lehmann R, et al.: Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection. Nat Med 2000;6:200-206. (Pubitemid 30082366)
-
(2000)
Nature Medicine
, vol.6
, Issue.2
, pp. 200-206
-
-
Baba, T.W.1
Liska, V.2
Hofmann-Lehmann, R.3
Vlasak, J.4
Xu, W.5
Ayehunie, S.6
Cavacini, L.A.7
Posner, M.R.8
Katinger, H.9
Stiegler, G.10
Bernacky, B.J.11
Rizvi, T.A.12
Schmidt, R.13
Hill, L.R.14
Keeling, M.E.15
Lu, Y.16
Wright, J.E.17
Chou, T.-C.18
Ruprecht, R.M.19
-
35
-
-
0037436188
-
Post-exposure prophylaxis with human monoclonal antibodies prevented SHIV89.6P infection or disease in neonatal macaques
-
DOI 10.1097/00002030-200302140-00003
-
Ferrantelli F, Hofmann-Lehmann R, Rasmussen RA, et al.: Post-exposure prophylaxis with human monoclonal antibodies prevented SHIV89.6P infection or disease in neonatal macaques. AIDS 2003;17:301-309. (Pubitemid 36223254)
-
(2003)
AIDS
, vol.17
, Issue.3
, pp. 301-309
-
-
Ferrantelli, F.1
Hofmann-Lehmann, R.2
Rasmussen, R.A.3
Wang, T.4
Xu, W.5
Li, P.-L.6
Montefiori, D.C.7
Cavacini, L.A.8
Katinger, H.9
Stiegler, G.10
Anderson, D.C.11
McClure, H.M.12
Ruprecht, R.M.13
-
36
-
-
8844219655
-
Passive immunization with the anti-HIV-1 human monoclonal antibody (hMAb) 4E10 and the hMAb combination 4E10/2F5/2G12
-
DOI 10.1093/jac/dkh428
-
Armbruster C, Stiegler GM, Vcelar BA, et al.: Passive immunization with the anti-HIV-1 human monoclonal antibody (hMAb) 4E10 and the hMAb combination 4E10/2F5/ 2G12. J Antimicrob Chemother 2004;54:915-920. (Pubitemid 39529987)
-
(2004)
Journal of Antimicrobial Chemotherapy
, vol.54
, Issue.5
, pp. 915-920
-
-
Armbruster, C.1
Stiegler, G.M.2
Vcelar, B.A.3
Jager, W.4
Koller, U.5
Jilch, R.6
Ammann, C.G.7
Pruenster, M.8
Stoiber, H.9
Katinger, H.W.D.10
-
37
-
-
20944446452
-
Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies
-
DOI 10.1038/nm1244
-
Trkola A, Kuster H, Rusert P, et al.: Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies. Nat Med 2005;11: 615-622. (Pubitemid 40868301)
-
(2005)
Nature Medicine
, vol.11
, Issue.6
, pp. 615-622
-
-
Trkola, A.1
Kuster, H.2
Rusert, P.3
Joos, B.4
Fischer, M.5
Leemann, C.6
Manrique, A.7
Huber, M.8
Rehr, M.9
Oxenius, A.10
Weber, R.11
Stiegler, G.12
Vcelar, B.13
Katinger, H.14
Aceto, L.15
Gunthard, H.F.16
-
38
-
-
0141521564
-
Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1
-
DOI 10.1128/JVI.77.19.10557-10565.2003
-
Labrijn AF, Poignard P, Raja A, et al.: Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1. J Virol 2003;77:10557-10565. (Pubitemid 37129699)
-
(2003)
Journal of Virology
, vol.77
, Issue.19
, pp. 10557-10565
-
-
Labrijn, A.F.1
Poignard, P.2
Raja, A.3
Zwick, M.B.4
Delgado, K.5
Franti, M.6
Binley, J.7
Vivona, V.8
Grundner, C.9
Huang, C.-C.10
Venturi, M.11
Petropoulos, C.J.12
Wrin, T.13
Dimitrov, D.S.14
Robinson, J.15
Kwong, P.D.16
Wyatt, R.T.17
Sodroski, J.18
Burton, D.R.19
-
39
-
-
0037076265
-
Broadly cross-reactive HIV-1-neutralizing human monoclonal Fab selected for binding to gp120-CD4-CCR5 complexes
-
DOI 10.1073/pnas.102562599
-
Moulard M, Phogat SK, Shu Y, et al.: Broadly cross-reactive HIV-1-neutralizing human monoclonal Fab selected for binding to gp120-CD4-CCR5 complexes. Proc Natl Acad Sci USA 2002;99:6913-6918. (Pubitemid 34526232)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.10
, pp. 6913-6918
-
-
Moulard, M.1
Phogat, S.K.2
Shu, Y.3
Labrijn, A.F.4
Xiao, D.5
Binley, J.M.6
Zhang, M.-Y.7
Sidorov, I.A.8
Broder, C.C.9
Robinson, J.10
Parren, P.W.H.I.11
Burton, D.R.12
Dimitrov, D.S.13
-
40
-
-
0344255655
-
Improved breadth and potency of an HIV-1-neutralizing human single-chain antibody by random mutagenesis and sequential antigen panning
-
DOI 10.1016/j.jmb.2003.09.055
-
Zhang MY, Shu Y, Rudolph D, et al.: Improved breadth and potency of an HIV-1-neutralizing human single-chain antibody by random mutagenesis and sequential antigen panning. J Mol Biol 2004;335:209-219. (Pubitemid 37494973)
-
(2004)
Journal of Molecular Biology
, vol.335
, Issue.1
, pp. 209-219
-
-
Zhang, M.-Y.1
Shu, Y.2
Rudolph, D.3
Prabakaran, P.4
Labrijn, A.F.5
Zwick, M.B.6
Lal, R.B.7
Dimitrov, D.S.8
-
41
-
-
77953664634
-
Potent and broad neutralizing activity of a single chain antibody fragment against cell-free and cell-associated HIV-1
-
Zhang MY, Borges AR, Ptak RG, et al.: Potent and broad neutralizing activity of a single chain antibody fragment against cell-free and cell-associated HIV-1. MAbs 2010;2: 266-274.
-
(2010)
MAbs
, vol.2
, pp. 266-274
-
-
Zhang, M.Y.1
Borges, A.R.2
Ptak, R.G.3
-
42
-
-
84860431821
-
Protective immunity: EAd inhibit in vivo HIV infection in humanized mice and can be expressed by lentiviral vectors to reprogram cells to secrete broadly neutralizing anti-HIV antibodies
-
Abstracts:
-
Zhang C, Zheng J, Chen W, Dimitrov DS, and Goldstein H: Protective immunity: eAd inhibit in vivo HIV infection in humanized mice and can be expressed by lentiviral vectors to reprogram cells to secrete broadly neutralizing anti-HIV antibodies. 18th Conference on Retroviruses and Opportunistic Infections 2011; Abstracts: 379.
-
(2011)
18th Conference on Retroviruses and Opportunistic Infections
, vol.379
-
-
Zhang, C.1
Zheng, J.2
Chen, W.3
Dimitrov, D.S.4
Goldstein, H.5
-
43
-
-
0024232289
-
Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: Significance of elevated interstitial pressure
-
Jain RK and Baxter LT: Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: Significance of elevated interstitial pressure. Cancer Res 1988;48:7022-7032. (Pubitemid 19013976)
-
(1988)
Cancer Research
, vol.48
, Issue.24
, pp. 7022-7032
-
-
Jain, R.K.1
Baxter, L.T.2
-
44
-
-
33846215917
-
Antibody constructs in cancer therapy: Protein engineering strategies to improve exposure in solid tumors
-
DOI 10.1002/cncr.22402
-
Beckman RA, Weiner LM, and Davis HM: Antibody constructs in cancer therapy: Protein engineering strategies to improve exposure in solid tumors. Cancer 2007;109:170-179. (Pubitemid 46106231)
-
(2007)
Cancer
, vol.109
, Issue.2
, pp. 170-179
-
-
Beckman, R.A.1
Weiner, L.M.2
Davis, H.M.3
-
45
-
-
0026709705
-
Inhibition of HIV infection by a novel CD4 domain 2-specific monoclonal antibody dissecting the basis for its inhibitory effect on HIV-induced cell fusion
-
Burkly LC, Olson D, Shapiro R, et al.: Inhibition of HIV infection by a novel CD4 domain 2-specific monoclonal antibody. Dissecting the basis for its inhibitory effect on HIV-induced cell fusion. J Immunol 1992;149:1779-1787.
-
(1992)
J. Immunol.
, vol.149
, pp. 1779-1787
-
-
Burkly, L.C.1
Olson, D.2
Shapiro, R.3
-
46
-
-
0026654557
-
A monoclonal antibody to CD4 domain 2 blocks soluble CD4- induced conformational changes in the envelope glycoproteins of human immunodeficiency virus type 1 (HIV-1) and HIV-1 infection of CD4+ cells
-
Moore JP, Sattentau QJ, Klasse PJ, and Burkly LC: A monoclonal antibody to CD4 domain 2 blocks soluble CD4- induced conformational changes in the envelope glycoproteins of human immunodeficiency virus type 1 (HIV-1) and HIV-1 infection of CD4+ cells. J Virol 1992;66:4784-4793.
-
(1992)
J. Virol.
, vol.66
, pp. 4784-4793
-
-
Moore, J.P.1
Sattentau, Q.J.2
Klasse, P.J.3
Burkly, L.C.4
-
47
-
-
0036343301
-
A humanized, nondepleting anti-CD4 antibody that blocks virus entry inhibits virus replication in rhesus monkeys chronically infected with simian immunodeficiency virus
-
Reimann KA, Khunkhun R, Lin W, Gordon W, and Fung M: A humanized, nondepleting anti-CD4 antibody that blocks virus entry inhibits virus replication in rhesus monkeys chronically infected with simian immunodeficiency virus. AIDS Res Hum Retroviruses 2002;18:747-755.
-
(2002)
AIDS Res. Hum. Retroviruses.
, vol.18
, pp. 747-755
-
-
Reimann, K.A.1
Khunkhun, R.2
Lin, W.3
Gordon, W.4
Fung, M.5
-
48
-
-
0030788879
-
A humanized form of a CD4-specific monoclonal antibody exhibits decreased antigenicity and prolonged plasma half-life in rhesus monkeys while retaining its unique biological and antiviral properties
-
Reimann KA, Lin W, Bixler S, et al.: A humanized form of a CD4-specific monoclonal antibody exhibits decreased antigenicity and prolonged plasma half-life in rhesus monkeys while retaining its unique biological and antiviral properties. AIDS Res Hum Retroviruses 1997;13:933-943. (Pubitemid 27334699)
-
(1997)
AIDS Research and Human Retroviruses
, vol.13
, Issue.11
, pp. 933-943
-
-
Reimann, K.A.1
Lin, W.2
Bixler, S.3
Browning, B.4
Ehrenfels, B.N.5
Lucci, J.6
Miatkowski, K.7
Olson, D.8
Parish, T.H.9
Rosa, M.D.10
Oleson, F.B.11
Hsu, Y.M.12
Padlan, E.A.13
Letvin, N.L.14
Burkly, L.C.15
-
49
-
-
0037006883
-
Development of anti-CD4 MAb hu5A8 for treatment of HIV-1 infection: Preclinical assessment in non-human primates
-
DOI 10.1016/S0300-483X(02)00002-1, PII S0300483X02000021
-
Boon L, Holland B, Gordon W, et al.: Development of anti- CD4 MAb hu5A8 for treatment of HIV-1 infection: Preclinical assessment in non-human primates. Toxicology 2002;172:191-203. (Pubitemid 34219385)
-
(2002)
Toxicology
, vol.172
, Issue.3
, pp. 191-203
-
-
Boon, L.1
Holland, B.2
Gordon, W.3
Liu, P.4
Shiau, F.5
Shanahan, W.6
Reimann, K.A.7
Fung, M.8
-
50
-
-
9144236197
-
Antiretroviral activity of the anti-CD4 monoclonal antibody TNX-355 in patients infected with HIV type 1
-
DOI 10.1086/380802
-
Kuritzkes DR, Jacobson J, Powderly WG, et al.: Antiretroviral activity of the anti-CD4 monoclonal antibody TNX-355 in patients infected with HIV type 1. J Infect Dis 2004;189:286-291. (Pubitemid 38147253)
-
(2004)
Journal of Infectious Diseases
, vol.189
, Issue.2
, pp. 286-291
-
-
Kuritzkes, D.R.1
Jacobson, J.2
Powderly, W.G.3
Godofsky, E.4
DeJesus, E.5
Haas, F.6
Reimann, K.A.7
Larson, J.L.8
Yarbough, P.O.9
Curt, V.10
Shanahan Jr., W.R.11
-
51
-
-
0035173073
-
Potent, broad-spectrum inhibition of human immunodeficiency virus type 1 by the CCR5 monoclonal antibody PRO 140
-
DOI 10.1128/JVI.75.2.579-588.2001
-
Trkola A, Ketas TJ, Nagashima KA, et al.: Potent, broadspectrum inhibition of human immunodeficiency virus type 1 by the CCR5 monoclonal antibody PRO 140. J Virol 2001;75:579-588. (Pubitemid 32037260)
-
(2001)
Journal of Virology
, vol.75
, Issue.2
, pp. 579-588
-
-
Trkola, A.1
Ketas, T.J.2
Nagashima, K.A.3
Zhao, L.4
Cilliers, T.5
Morris, L.6
Moore, J.P.7
Maddon, P.J.8
Olson, W.C.9
-
52
-
-
0032902710
-
Differential inhibition of human immunodeficiency virus type 1 fusion, gp120 binding, and CC-chemokine activity by monoclonal antibodies to CCR5
-
Olson WC, Rabut GE, Nagashima KA, et al.: Differential inhibition of human immunodeficiency virus type 1 fusion, gp120 binding, and CC-chemokine activity by monoclonal antibodies to CCR5. J Virol 1999;73:4145-4155. (Pubitemid 29189860)
-
(1999)
Journal of Virology
, vol.73
, Issue.5
, pp. 4145-4155
-
-
Olson, W.C.1
Rabut, G.E.E.2
Nagashima, K.A.3
Tran, D.N.H.4
Anselma, D.J.5
Monard, S.P.6
Segal, J.P.7
Thompson, D.A.D.8
Kajumo, F.9
Guo, Y.10
Moore, J.P.11
Maddon, P.J.12
Dragic, T.13
-
53
-
-
54249125999
-
Antiviral activity of single-dose PRO 140, a CCR5 monoclonal antibody, in HIV-infected adults
-
Jacobson JM, Saag MS, Thompson MA, et al.: Antiviral activity of single-dose PRO 140, a CCR5 monoclonal antibody, in HIV-infected adults. J Infect Dis 2008;198:1345-1352.
-
(2008)
J. Infect. Dis.
, vol.198
, pp. 1345-1352
-
-
Jacobson, J.M.1
Saag, M.S.2
Thompson, M.A.3
-
55
-
-
21344434534
-
Immunology: Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies
-
DOI 10.1126/science.1111781
-
Haynes BF, Fleming J, St Clair EW, et al.: Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies. Science 2005;308:1906-1908. (Pubitemid 40941873)
-
(2005)
Science
, vol.308
, Issue.5730
, pp. 1906-1908
-
-
Haynes, B.F.1
Fleming, J.2
St. Clair, E.W.3
Katinger, H.4
Stiegler, G.5
Kunert, R.6
Robinson, J.7
Scearce, R.M.8
Plonk, K.9
Staats, H.F.10
Ortel, T.L.11
Liao, H.-X.12
Alam, S.M.13
-
56
-
-
60549089534
-
Lipid binding properties of 4E10, 2F5, and WR304 monoclonal antibodies that neutralize HIV-1
-
Matyas GR, Beck Z, Karasavvas N, and Alving CR: Lipid binding properties of 4E10, 2F5, and WR304 monoclonal antibodies that neutralize HIV-1. Biochim Biophys Acta 2009;1788:660-665.
-
(2009)
Biochim. Biophys. Acta.
, vol.1788
, pp. 660-665
-
-
Matyas, G.R.1
Beck, Z.2
Karasavvas, N.3
Alving, C.R.4
-
57
-
-
77953655567
-
Maturation pathways of cross-reactive HIV-1 neutralizing antibodies
-
Xiao XD, Chen WZ, Feng Y, and Dimitrov DS: Maturation pathways of cross-reactive HIV-1 neutralizing antibodies. Viruses-Basel 2009;1:802-817.
-
(2009)
Viruses-Basel
, vol.1
, pp. 802-817
-
-
Xiao, X.D.1
Chen, W.Z.2
Feng, Y.3
Dimitrov, D.S.4
-
58
-
-
33947203546
-
Resistance of HIV-1 to the broadly HIV-1-neutralizing, anti-carbohydrate antibody 2G12
-
DOI 10.1016/j.virol.2006.10.027, PII S0042682206007781
-
Huskens D, Van Laethem K, Vermeire K, Balzarini J, and Schols D: Resistance of HIV-1 to the broadly HIV-1- neutralizing, anti-carbohydrate antibody 2G12. Virology 2007;360:294-304. (Pubitemid 46482610)
-
(2007)
Virology
, vol.360
, Issue.2
, pp. 294-304
-
-
Huskens, D.1
Van Laethem, K.2
Vermeire, K.3
Balzarini, J.4
Schols, D.5
-
59
-
-
34547808791
-
In vivo and in vitro escape from neutralizing antibodies 2G12, 2F5, and 4E10
-
DOI 10.1128/JVI.00598-07
-
Manrique A, Rusert P, Joos B, et al.: In vivo and in vitro escape from neutralizing antibodies 2G12, 2F5, and 4E10. J Virol 2007;81:8793-8808. (Pubitemid 47242852)
-
(2007)
Journal of Virology
, vol.81
, Issue.16
, pp. 8793-8808
-
-
Manrique, A.1
Rusert, P.2
Joos, B.3
Fischer, M.4
Kuster, H.5
Leemann, C.6
Niederost, B.7
Weber, R.8
Stiegler, G.9
Katinger, H.10
Gunthard, H.F.11
Trkola, A.12
-
60
-
-
0028101448
-
Analysis of the structural correlates for antibody polyreactivity by multiple reassortments of chimeric human immunoglobulin heavy and light chain V segments
-
DOI 10.1084/jem.180.3.885
-
Ichiyoshi Y and Casali P: Analysis of the structural correlates for antibody polyreactivity by multiple reassortments of chimeric human immunoglobulin heavy and light chain V segments. J Exp Med 1994;180:885-895. (Pubitemid 24256601)
-
(1994)
Journal of Experimental Medicine
, vol.180
, Issue.3
, pp. 885-895
-
-
Ichiyoshi, Y.1
Casali, P.2
-
61
-
-
73949133588
-
Role of HIV membrane in neutralization by two broadly neutralizing antibodies
-
Alam SM, Morelli M, Dennison SM, et al.: Role of HIV membrane in neutralization by two broadly neutralizing antibodies. Proc Natl Acad Sci USA 2009;106:20234-20239.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 20234-20239
-
-
Alam, S.M.1
Morelli, M.2
Dennison, S.M.3
-
62
-
-
76249083814
-
Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance
-
Verkoczy L, Diaz M, Holl TM, et al.: Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance. Proc Natl Acad Sci USA 2010;107:181-186.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 181-186
-
-
Verkoczy, L.1
Diaz, M.2
Holl, T.M.3
-
63
-
-
66149132686
-
Examination of the contributions of size and avidity to the neutralization mechanisms of the anti-HIV antibodies b12 and 4E10
-
Klein JS, Gnanapragasam PN, Galimidi RP, Foglesong CP, West AP, Jr., and Bjorkman PJ: Examination of the contributions of size and avidity to the neutralization mechanisms of the anti-HIV antibodies b12 and 4E10. Proc Natl Acad Sci USA 2009;106:7385-7390.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 7385-7390
-
-
Klein, J.S.1
Gnanapragasam, P.N.2
Galimidi, R.P.3
Foglesong, C.P.4
West Jr., A.P.5
Bjorkman, P.J.6
-
64
-
-
3843139398
-
Characterization of molecular features, antigen-binding, and in vitro properties of IgG and IgM variants of 4E10, an anti-HIV type 1 neutralizing monoclonal antibody
-
DOI 10.1089/0889222041524571
-
Kunert R, Wolbank S, Stiegler G, Weik R, and Katinger H: Characterization of molecular features, antigen-binding, and in vitro properties of IgG and IgM variants of 4E10, an anti- HIV type 1 neutralizing monoclonal antibody. AIDS Res Hum Retroviruses 2004;20:755-762. (Pubitemid 39037507)
-
(2004)
AIDS Research and Human Retroviruses
, vol.20
, Issue.7
, pp. 755-762
-
-
Kunert, R.1
Wolbank, S.2
Stiegler, G.3
Weik, R.4
Katinger, H.5
-
65
-
-
41649090223
-
A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies
-
DOI 10.1073/pnas.0800255105
-
Frey G, Peng H, Rits-Volloch S, Morelli M, Cheng Y, and Chen B: A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies. Proc Natl Acad Sci USA 2008;105:3739-3744. (Pubitemid 351723468)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.10
, pp. 3739-3744
-
-
Frey, G.1
Peng, H.2
Rits-Volloch, S.3
Morelli, M.4
Cheng, Y.5
Chen, B.6
-
66
-
-
53749101563
-
Sequestering of the prehairpin intermediate of gp41 by peptide N36Mut(e,g) potentiates the human immunodeficiency virus type 1 neutralizing activity of monoclonal antibodies directed against the N-terminal helical repeat of gp41
-
Gustchina E, Bewley CA, and Clore GM: Sequestering of the prehairpin intermediate of gp41 by peptide N36Mut(e,g) potentiates the human immunodeficiency virus type 1 neutralizing activity of monoclonal antibodies directed against the N-terminal helical repeat of gp41. J Virol 2008;82:10032-10041.
-
(2008)
J. Virol.
, vol.82
, pp. 10032-10041
-
-
Gustchina, E.1
Bewley, C.A.2
Clore, G.M.3
-
67
-
-
77953668210
-
Affinity maturation and characterization of a human monoclonal antibody against HIV-1 gp41
-
Montgomery DL, Wang YJ, Hrin R, et al.: Affinity maturation and characterization of a human monoclonal antibody against HIV-1 gp41. MAbs 2009;1:462-474.
-
(2009)
MAbs
, vol.1
, pp. 462-474
-
-
Montgomery, D.L.1
Wang, Y.J.2
Hrin, R.3
-
69
-
-
56749185286
-
Characterization of the steric defense of the HIV-1 gp41 N-trimer region
-
Eckert DM, Shi Y, Kim S, et al.: Characterization of the steric defense of the HIV-1 gp41 N-trimer region. Protein Sci 2008;17:2091-2100.
-
(2008)
Protein Sci.
, vol.17
, pp. 2091-2100
-
-
Eckert, D.M.1
Shi, Y.2
Kim, S.3
-
70
-
-
47049130702
-
Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody that recognizes a novel conformational epitope on gp41 and lacks reactivity against self-antigens
-
DOI 10.1128/JVI.00033-08
-
Zhang MY, Vu BK, Choudhary A, et al.: Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody that recognizes a novel conformational epitope on gp41 and lacks reactivity against self-antigens. J Virol 2008;82:6869-6879. (Pubitemid 351977708)
-
(2008)
Journal of Virology
, vol.82
, Issue.14
, pp. 6869-6879
-
-
Zhang, M.-Y.1
Vu, B.K.2
Choudhary, A.3
Lu, H.4
Humbert, M.5
Ong, H.6
Alam, M.7
Ruprecht, R.M.8
Quinnan, G.9
Jiang, S.10
Montefiori, D.C.11
Mascola, J.R.12
Broder, C.C.13
Haynes, B.F.14
Dimitrov, D.S.15
-
71
-
-
34247559067
-
Cross-reactive HIV-1 neutralizing monoclonal antibodies selected by screening of an immune human phage library against an envelope glycoprotein (gp140) isolated from a patient (R2) with broadly HIV-1 neutralizing antibodies
-
DOI 10.1016/j.virol.2007.01.015, PII S0042682207000311
-
Choudhry V, Zhang MY, Sidorov IA, et al.: Cross-reactive HIV-1 neutralizing monoclonal antibodies selected by screening of an immune human phage library against an envelope glycoprotein (gp140) isolated from a patient (R2) with broadly HIV-1 neutralizing antibodies. Virology 2007; 363:79-90. (Pubitemid 46678166)
-
(2007)
Virology
, vol.363
, Issue.1
, pp. 79-90
-
-
Choudhry, V.1
Zhang, M.-Y.2
Sidorov, I.A.3
Louis, J.M.4
Harris, I.5
Dimitrov, A.S.6
Bouma, P.7
Cham, F.8
Choudhary, A.9
Rybak, S.M.10
Fouts, T.11
Montefiori, D.C.12
Broder, C.C.13
Quinnan Jr., G.V.14
Dimitrov, D.S.15
-
72
-
-
34247569794
-
Selection of a novel gp41-specific HIV-1 neutralizing human antibody by competitive antigen panning
-
DOI 10.1016/j.jim.2006.09.016, PII S0022175906002675
-
Zhang MY, Choudhry V, Sidorov IA, et al.: Selection of a novel gp41-specific HIV-1 neutralizing human antibody by competitive antigen panning. J Immunol Methods 2006;317:21-30. (Pubitemid 44822553)
-
(2006)
Journal of Immunological Methods
, vol.317
, Issue.1-2
, pp. 21-30
-
-
Zhang, M.-Y.1
Choudhry, V.2
Sidorov, I.A.3
Tenev, V.4
Vu, B.K.5
Choudhary, A.6
Lu, H.7
Stiegler, G.M.8
Katinger, H.W.D.9
Jiang, S.10
Broder, C.C.11
Dimitrov, D.S.12
-
73
-
-
33747421769
-
Increased efficacy of HIV-1 neutralization by antibodies at low CCR5 surface concentration
-
DOI 10.1016/j.bbrc.2006.07.163, PII S0006291X06017463
-
Choudhry V, Zhang MY, Harris I, et al.: Increased efficacy of HIV-1 neutralization by antibodies at low CCR5 surface concentration. Biochem Biophys Res Commun 2006;348: 1107-1115. (Pubitemid 44251203)
-
(2006)
Biochemical and Biophysical Research Communications
, vol.348
, Issue.3
, pp. 1107-1115
-
-
Choudhry, V.1
Zhang, M.-Y.2
Harris, I.3
Sidorov, I.A.4
Vu, B.5
Dimitrov, A.S.6
Fouts, T.7
Dimitrov, D.S.8
-
74
-
-
44649191357
-
Traitors of the immune system-enhancing antibodies in HIV infection: Their possible implication in HIV vaccine development
-
Beck Z, Prohaszka Z, and Fust G: Traitors of the immune system-enhancing antibodies in HIV infection: Their possible implication in HIV vaccine development. Vaccine 2008;26:3078-3085.
-
(2008)
Vaccine
, vol.26
, pp. 3078-3085
-
-
Beck, Z.1
Prohaszka, Z.2
Fust, G.3
-
75
-
-
70350134276
-
Cross-reactive monoclonal antibodies to multiple HIV-1 subtype and SIVcpz envelope glycoproteins
-
Gao F, Scearce RM, Alam SM, et al.: Cross-reactive monoclonal antibodies to multiple HIV-1 subtype and SIVcpz envelope glycoproteins. Virology 2009;394:91-98.
-
(2009)
Virology
, vol.394
, pp. 91-98
-
-
Gao, F.1
Scearce, R.M.2
Alam, S.M.3
-
76
-
-
33947132164
-
Production and characterization of high-affinity human monoclonal antibodies to human immunodeficiency virus type 1 envelope glycoproteins in a mouse model expressing human immunoglobulins
-
DOI 10.1128/CVI.00274-06
-
Sheppard NC, Davies SL, Jeffs SA, Vieira SM, and Sattentau QJ: Production and characterization of high-affinity human monoclonal antibodies to human immunodeficiency virus type 1 envelope glycoproteins in a mouse model expressing human immunoglobulins. Clin Vaccine Immunol 2007; 14:157-167. (Pubitemid 46407068)
-
(2007)
Clinical and Vaccine Immunology
, vol.14
, Issue.2
, pp. 157-167
-
-
Sheppard, N.C.1
Davies, S.L.2
Jeffs, S.A.3
Vieira, S.M.4
Sattentau, Q.J.5
-
77
-
-
79952077439
-
Cross-reactive human IgMderived monoclonal antibodies that bind to HIV-1 envelope glycoproteins
-
Chen W, Zhu Z, Liao H, et al.: Cross-reactive human IgMderived monoclonal antibodies that bind to HIV-1 envelope glycoproteins. Viruses 2010;2:547-565.
-
(2010)
Viruses
, vol.2
, pp. 547-565
-
-
Chen, W.1
Zhu, Z.2
Liao, H.3
-
78
-
-
0035168058
-
Immunogenicity and protective efficacy of oligomeric human immunodeficiency virus type 1 gp140
-
DOI 10.1128/JVI.75.2.645-653.2001
-
Earl PL, Sugiura W, Montefiori DC, et al.: Immunogenicity and protective efficacy of oligomeric human immunodeficiency virus type 1 gp140. J Virol 2001;75:645-653. (Pubitemid 32037268)
-
(2001)
Journal of Virology
, vol.75
, Issue.2
, pp. 645-653
-
-
Earl, P.L.1
Sugiura, W.2
Montefiori, D.C.3
Broder, C.C.4
Lee, S.A.5
Wild, C.6
Lifson, J.7
Moss, B.8
-
79
-
-
0035155850
-
Improved elicitation of neutralizing antibodies against primary human immunodeficiency viruses by soluble stabilized envelope glycoprotein trimers
-
DOI 10.1128/JVI.75.3.1165-1171.2001
-
Yang X, Wyatt R, and Sodroski J: Improved elicitation of neutralizing antibodies against primary human immunodeficiency viruses by soluble stabilized envelope glycoprotein trimers. J Virol 2001;75:1165-1171. (Pubitemid 32094675)
-
(2001)
Journal of Virology
, vol.75
, Issue.3
, pp. 1165-1171
-
-
Yang, X.1
Wyatt, R.2
Sodroski, J.3
-
80
-
-
68249114530
-
CD4-BFFI: A novel, bifunctional HIV-1 entry inhibitor with high and broad antiviral potency
-
Jekle A, Chow E, Kopetzki E, et al.: CD4-BFFI: a novel, bifunctional HIV-1 entry inhibitor with high and broad antiviral potency. Antiviral Res 2009;83:257-266.
-
(2009)
Antiviral. Res.
, vol.83
, pp. 257-266
-
-
Jekle, A.1
Chow, E.2
Kopetzki, E.3
-
81
-
-
64149095857
-
CD4-anchoring HIV-1 fusion inhibitor with enhanced potency and in vivo stability
-
Ji C, Kopetzki E, Jekle A, et al.: CD4-anchoring HIV-1 fusion inhibitor with enhanced potency and in vivo stability. J Biol Chem 2009;284:5175-5185.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 5175-5185
-
-
Ji, C.1
Kopetzki, E.2
Jekle, A.3
-
82
-
-
0037372301
-
Neutralization of human immunodeficiency virus type 1 by sCD4-17b, a single-chain chimeric protein, based on sequential interaction of gp120 with CD4 and coreceptor
-
DOI 10.1128/JVI.77.5.2859-2865.2003
-
Dey B, Del Castillo CS, and Berger EA: Neutralization of human immunodeficiency virus type 1 by sCD4-17b, a single- chain chimeric protein, based on sequential interaction of gp120 with CD4 and coreceptor. J Virol 2003;77:2859-2865. (Pubitemid 36228069)
-
(2003)
Journal of Virology
, vol.77
, Issue.5
, pp. 2859-2865
-
-
Dey, B.1
Del Castillo, C.S.2
Berger, E.A.3
-
83
-
-
77949446701
-
SCD4-17b bifunctional protein: Extremely broad and potent neutralization of HIV-1 Env pseudotyped viruses from genetically diverse primary isolates
-
Lagenaur LA, Villarroel VA, Bundoc V, Dey B, and Berger EA: sCD4-17b bifunctional protein: Extremely broad and potent neutralization of HIV-1 Env pseudotyped viruses from genetically diverse primary isolates. Retrovirology 2010;7:11.
-
(2010)
Retrovirology
, vol.7
, pp. 11
-
-
Lagenaur, L.A.1
Villarroel, V.A.2
Bundoc, V.3
Dey, B.4
Berger, E.A.5
-
84
-
-
72849116535
-
Evaluation of CD4-CD4i antibody architectures yields potent, broadly cross-reactive anti-human immunodeficiency virus reagents
-
West AP, Jr., Galimidi RP, Foglesong CP, Gnanapragasam PN, Klein JS, and Bjorkman PJ: Evaluation of CD4-CD4i antibody architectures yields potent, broadly cross-reactive anti-human immunodeficiency virus reagents. J Virol 2010; 84:261-269.
-
(2010)
J. Virol.
, vol.84
, pp. 261-269
-
-
West Jr., A.P.1
Galimidi, R.P.2
Foglesong, C.P.3
Gnanapragasam, P.N.4
Klein, J.S.5
Bjorkman, P.J.6
-
85
-
-
77956913427
-
Bifunctional fusion proteins of the human engineered antibody domain m36 with human soluble CD4 are potent inhibitors of diverse HIV-1 isolates
-
Chen W, Xiao X, Wang Y, Zhu Z, and Dimitrov DS: Bifunctional fusion proteins of the human engineered antibody domain m36 with human soluble CD4 are potent inhibitors of diverse HIV-1 isolates. Antiviral Res 2010;88:107-115.
-
(2010)
Antiviral. Res.
, vol.88
, pp. 107-115
-
-
Chen, W.1
Xiao, X.2
Wang, Y.3
Zhu, Z.4
Dimitrov, D.S.5
-
86
-
-
57349165849
-
Llama antibody fragments with cross-subtype human immunodeficiency virus type 1 (HIV-1)-neutralizing properties and high affinity for HIV-1 gp120
-
Forsman A, Beirnaert E, Aasa-Chapman MM, et al.: Llama antibody fragments with cross-subtype human immunodeficiency virus type 1 (HIV-1)-neutralizing properties and high affinity for HIV-1 gp120. J Virol 2008;82:12069-12081.
-
(2008)
J. Virol.
, vol.82
, pp. 12069-12081
-
-
Forsman, A.1
Beirnaert, E.2
Aasa-Chapman, M.M.3
-
87
-
-
80052499557
-
Engineered single human CD4 domains as potent HIV-1 inhibitors and components of vaccine immunogens
-
Chen W, Feng Y, Gong R, et al.: Engineered single human CD4 domains as potent HIV-1 inhibitors and components of vaccine immunogens. J Virol 2011;85(18):9395-9405.
-
(2011)
J. Virol.
, vol.85
, Issue.18
, pp. 9395-9405
-
-
Chen, W.1
Feng, Y.2
Gong, R.3
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