-
2
-
-
0036781052
-
NF-κB regulation in the immune system
-
Li, Q., and Verma, I. M. (2002) NF-κB regulation in the immune system. Nat. Rev. Immunol. 2, 725-734
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 725-734
-
-
Li, Q.1
Verma, I.M.2
-
3
-
-
0037044575
-
The IκB-NF-κB signaling module
-
Hoffmann, A., Levchenko, A., Scott, M. L., and Baltimore, D. (2002) The IκB-NF-κB signaling module. Temporal control and selective gene activation. Science 298, 1241-1245
-
(2002)
Temporal Control and Selective Gene Activation. Science
, vol.298
, pp. 1241-1245
-
-
Hoffmann, A.1
Levchenko, A.2
Scott, M.L.3
Baltimore, D.4
-
4
-
-
0027168447
-
NF-κB controls expression of inhibitor IκBα
-
Sun, S. C., Ganchi, P. A., Ballard, D. W., and Greene, W. C. (1993) NF-κB controls expression of inhibitor IκBα. Evidence for an inducible autoregulatory pathway. Science 259, 1912-1915
-
(1993)
Evidence for An Inducible Autoregulatory Pathway. Science
, vol.259
, pp. 1912-1915
-
-
Sun, S.C.1
Ganchi, P.A.2
Ballard, D.W.3
Greene, W.C.4
-
5
-
-
69249205739
-
Obesity, inflammation, and atherosclerosis
-
Rocha, V. Z., and Libby, P. (2009) Obesity, inflammation, and atherosclerosis. Nat. Rev. Cardiol. 6, 399-409
-
(2009)
Nat. Rev. Cardiol.
, vol.6
, pp. 399-409
-
-
Rocha, V.Z.1
Libby, P.2
-
6
-
-
0025120749
-
The ETS-domain: A new DNA-binding motif that recognizes a purine-rich core DNA sequence
-
Karim, F. D., Urness, L. D., Thummel, C. S., Klemsz, M. J., McKercher, S. R., Celada, A., Van Beveren, C., Maki, R. A., Gunther, C. V., and Nye, J. A. (1990) The ETS domain. A new DNA-binding motif that recognizes a purine-rich core DNA sequence. Genes Dev. 4, 1451-1453 (Pubitemid 20310065)
-
(1990)
Genes and Development
, vol.4
, Issue.9
, pp. 1451-1453
-
-
Karim, F.D.1
Urness, L.D.2
Thummel, C.S.3
Klemsz, M.J.4
McKercher, S.R.5
Celada, A.6
Van Beveren, C.7
Maki, R.A.8
Gunther, C.V.9
Nye, J.A.10
Graves, B.J.11
-
7
-
-
7444252292
-
Expression profiles frame the promoter specificity dilemma of the ETS family of transcription factors
-
DOI 10.1093/nar/gkh906
-
Hollenhorst, P. C., Jones, D. A., and Graves, B. J. (2004) Expression profiles frame the promoter specificity dilemma of the ETS family of transcription factors. Nucleic Acids Res. 32, 5693-5702 (Pubitemid 39545685)
-
(2004)
Nucleic Acids Research
, vol.32
, Issue.18
, pp. 5693-5702
-
-
Hollenhorst, P.C.1
Jones, D.A.2
Graves, B.J.3
-
8
-
-
33745085292
-
Endoglin expression in the endothelium is regulated by Fli-1, Erg, and Elf-1 acting on the promoter and a -8-kb enhancer
-
DOI 10.1182/blood-2005-12-4929
-
Pimanda, J. E., Chan, W. Y., Donaldson, I. J., Bowen, M., Green, A. R., and Göttgens, B. (2006) Endoglin expression in the endothelium is regulated by Fli-1, Erg, and Elf-1 acting on the promoter and a -8-kb enhancer. Blood 107, 4737-4745 (Pubitemid 43882624)
-
(2006)
Blood
, vol.107
, Issue.12
, pp. 4737-4745
-
-
Pimanda, J.E.1
Chan, W.Y.I.2
Donaldson, I.J.3
Bowen, M.4
Green, A.R.5
Gottgens, B.6
-
9
-
-
0033373135
-
Characterisation of the tumour necrosis factor (TNF)-α response elements in the human ICAM-2 promoter
-
McLaughlin, F., Ludbrook, V. J., Kola, I., Campbell, C. J., and Randi, A. M. (1999) Characterization of the tumor necrosis factor (TNF)-α response elements in the human ICAM-2 promoter. J. Cell Sci. 112, 4695-4703 (Pubitemid 30034817)
-
(1999)
Journal of Cell Science
, vol.112
, Issue.24
, pp. 4695-4703
-
-
McLaughlin, F.1
Ludbrook, V.J.2
Kola, I.3
Campbell, C.J.4
Randi, A.M.5
-
10
-
-
43549123588
-
Transcription factor Erg regulates angiogenesis and endothelial apoptosis through VE-cadherin
-
Birdsey, G. M., Dryden, N. H., Amsellem, V., Gebhardt, F., Sahnan, K., Haskard, D. O., Dejana, E., Mason, J. C., and Randi, A. M. (2008) Transcription factor Erg regulates angiogenesis and endothelial apoptosis through VE-cadherin. Blood 111, 3498-3506
-
(2008)
Blood
, vol.111
, pp. 3498-3506
-
-
Birdsey, G.M.1
Dryden, N.H.2
Amsellem, V.3
Gebhardt, F.4
Sahnan, K.5
Haskard, D.O.6
Dejana, E.7
Mason, J.C.8
Randi, A.M.9
-
11
-
-
0033103725
-
Upregulation of human heme oxygenase gene expression by Ets-family proteins
-
DOI 10.1002/(SICI)1097-4644(19990301)72:3<311::AID-JCB1>3.0.CO;2-G
-
Deramaudt, B. M., Remy, P., and Abraham, N. G. (1999) Up-regulation of human heme oxygenase gene expression by Ets family proteins. J. Cell. Biochem. 72, 311-321 (Pubitemid 29047394)
-
(1999)
Journal of Cellular Biochemistry
, vol.72
, Issue.3
, pp. 311-321
-
-
Deramaudt, B.M.J.-M.1
Remy, P.2
Abraham, N.G.3
-
12
-
-
78650885048
-
The transcription factor Erg inhibits vascular inflammation by repressing NF-κB activation and proinflammatory gene expression in endothelial cells
-
Sperone, A., Dryden, N. H., Birdsey, G. M., Madden, L., Johns, M., Evans, P. C., Mason, J. C., Haskard, D. O., Boyle, J. J., Paleolog, E. M., and Randi, A. M. (2011) The transcription factor Erg inhibits vascular inflammation by repressing NF-κB activation and proinflammatory gene expression in endothelial cells. Arterioscler. Thromb. Vasc. Biol. 31, 142-150
-
(2011)
Arterioscler. Thromb. Vasc. Biol.
, vol.31
, pp. 142-150
-
-
Sperone, A.1
Dryden, N.H.2
Birdsey, G.M.3
Madden, L.4
Johns, M.5
Evans, P.C.6
Mason, J.C.7
Haskard, D.O.8
Boyle, J.J.9
Paleolog, E.M.10
Randi, A.M.11
-
13
-
-
66149106668
-
Anti-inflammatory effects of the ETS factor ERG in endothelial cells are mediated through transcriptional repression of the interleukin-8 gene
-
Yuan, L., Nikolova-Krstevski, V., Zhan, Y., Kondo, M., Bhasin, M., Varghese, L., Yano, K., Carman, C. V., Aird, W. C., and Oettgen, P. (2009) Anti-inflammatory effects of the ETS factor ERG in endothelial cells are mediated through transcriptional repression of the interleukin-8 gene. Circ. Res. 104, 1049-1057
-
(2009)
Circ. Res.
, vol.104
, pp. 1049-1057
-
-
Yuan, L.1
Nikolova-Krstevski, V.2
Zhan, Y.3
Kondo, M.4
Bhasin, M.5
Varghese, L.6
Yano, K.7
Carman, C.V.8
Aird, W.C.9
Oettgen, P.10
-
14
-
-
0028929371
-
Coupling of a signal response domain in IκBα to multiple pathways for NF-κB activation
-
Brockman, J. A., Scherer, D. C., McKinsey, T. A., Hall, S. M., Qi, X., Lee, W. Y., and Ballard, D. W. (1995) Coupling of a signal response domain in IκBα to multiple pathways for NF-κB activation. Mol. Cell. Biol. 15, 2809-2818
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 2809-2818
-
-
Brockman, J.A.1
Scherer, D.C.2
McKinsey, T.A.3
Hall, S.M.4
Qi, X.5
Lee, W.Y.6
Ballard, D.W.7
-
15
-
-
0028921613
-
Transcriptional regulation of the intercellular adhesion molecule-1 gene by inflammatory cytokines in human endothelial cells. Essential roles of a variant NF-κB site and p65 homodimers
-
Ledebur, H. C., and Parks, T. P. (1995) Transcriptional regulation of the intercellular adhesion molecule-1 gene by inflammatory cytokines in human endothelial cells. Essential roles of a variant NF-κB site and p65 homodimers. J. Biol. Chem. 270, 933-943
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 933-943
-
-
Ledebur, H.C.1
Parks, T.P.2
-
16
-
-
84856076500
-
The transcription factor Erg regulates expression of histone deacetylase 6 and multiple pathways involved in endothelial cell migration and angiogenesis
-
Birdsey, G. M., Dryden, N. H., Shah, A. V., Hannah, R., Hall, M. D., Haskard, D. O., Parsons, M., Mason, J. C., Zvelebil, M., Gottgens, B., Ridley, A. J., and Randi, A. M. (2012) The transcription factor Erg regulates expression of histone deacetylase 6 and multiple pathways involved in endothelial cell migration and angiogenesis. Blood 119, 894-903
-
(2012)
Blood
, vol.119
, pp. 894-903
-
-
Birdsey, G.M.1
Dryden, N.H.2
Shah, A.V.3
Hannah, R.4
Hall, M.D.5
Haskard, D.O.6
Parsons, M.7
Mason, J.C.8
Zvelebil, M.9
Gottgens, B.10
Ridley, A.J.11
Randi, A.M.12
-
17
-
-
56449120810
-
IκBα kinase inhibitor IKI-1 conferred tumor necrosis factor α sensitivity to pancreatic cancer cells and a xenograft tumor model
-
Zhang, Y., Gavriil, M., Lucas, J., Mandiyan, S., Follettie, M., Diesl, V., Sum, F. W., Powell, D., Haney, S., Abraham, R., and Arndt, K. (2008) IκBα kinase inhibitor IKI-1 conferred tumor necrosis factor α sensitivity to pancreatic cancer cells and a xenograft tumor model. Cancer Res. 68, 9519-9524
-
(2008)
Cancer Res.
, vol.68
, pp. 9519-9524
-
-
Zhang, Y.1
Gavriil, M.2
Lucas, J.3
Mandiyan, S.4
Follettie, M.5
Diesl, V.6
Sum, F.W.7
Powell, D.8
Haney, S.9
Abraham, R.10
Arndt, K.11
-
18
-
-
14644402496
-
Microarray analysis of primary endothelial cells challenged with different inflammatory and immune cytokines
-
DOI 10.1016/j.cyto.2004.11.003
-
Sana, T. R., Janatpour, M. J., Sathe, M., McEvoy, L. M., and McClanahan, T. K. (2005) Microarray analysis of primary endothelial cells challenged with different inflammatory and immune cytokines. Cytokine 29, 256-269 (Pubitemid 40320926)
-
(2005)
Cytokine
, vol.29
, Issue.6
, pp. 256-269
-
-
Sana, T.R.1
Janatpour, M.J.2
Sathe, M.3
McEvoy, L.M.4
McClanahan, T.K.5
-
19
-
-
78650210727
-
Bcl-6 and NF-κB cistromes mediate opposing regulation of the innate immune response
-
Barish, G. D., Yu, R. T., Karunasiri, M., Ocampo, C. B., Dixon, J., Benner, C., Dent, A. L., Tangirala, R. K., and Evans, R. M. (2010) Bcl-6 and NF-κB cistromes mediate opposing regulation of the innate immune response. Genes Dev. 24, 2760-2765
-
(2010)
Genes Dev.
, vol.24
, pp. 2760-2765
-
-
Barish, G.D.1
Yu, R.T.2
Karunasiri, M.3
Ocampo, C.B.4
Dixon, J.5
Benner, C.6
Dent, A.L.7
Tangirala, R.K.8
Evans, R.M.9
-
20
-
-
0026784640
-
Structure and expression of human Fli-1 gene
-
Prasad, D. D., Rao, V. N., and Reddy, E. S. (1992) Structure and expression of human Fli-1 gene. Cancer Res. 52, 5833-5837
-
(1992)
Cancer Res.
, vol.52
, pp. 5833-5837
-
-
Prasad, D.D.1
Rao, V.N.2
Reddy, E.S.3
-
21
-
-
30644463934
-
Brain-specific angiogenesis inhibitor 2 regulates VEGF through GABP that acts as a transcriptional repressor
-
DOI 10.1016/j.febslet.2005.12.086, PII S0014579305015711
-
Jeong, B. C., Kim, M. Y., Lee, J. H., Kee, H. J., Kho, D. H., Han, K. E., Qian, Y. R., Kim, J. K., and Kim, K. K. (2006) Brain-specific angiogenesis inhibitor 2 regulates VEGF through GABP that acts as a transcriptional repressor. FEBS Lett. 580, 669-676 (Pubitemid 43089703)
-
(2006)
FEBS Letters
, vol.580
, Issue.2
, pp. 669-676
-
-
Jeong, B.C.1
Kim, M.-Y.2
Lee, J.H.3
Kee, H.J.4
Kho, D.H.5
Han, K.E.6
Qian, Y.R.7
Kim, J.-K.8
Kim, K.K.9
-
22
-
-
34250868931
-
A three-kilobase fragment of the human Robo4 promoter directs cell type-specific expression in endothelium
-
DOI 10.1161/01.RES.0000269779.10644.dc
-
Okada, Y., Yano, K., Jin, E., Funahashi, N., Kitayama, M., Doi, T., Spokes, K., Beeler, D. L., Shih, S. C., Okada, H., Danilov, T. A., Maynard, E., Minami, T., Oettgen, P., and Aird, W. C. (2007) A 3-kb fragment of the human Robo4 promoter directs cell type-specific expression in endothelium. Circ. Res. 100, 1712-1722 (Pubitemid 46987863)
-
(2007)
Circulation Research
, vol.100
, Issue.12
, pp. 1712-1722
-
-
Okada, Y.1
Yano, K.2
Jin, E.3
Funahashi, N.4
Kitayama, M.5
Doi, T.6
Spokes, K.7
Beeler, D.L.8
Shih, S.-C.9
Okada, H.10
Danilov, T.A.11
Maynard, E.12
Minami, T.13
Oettgen, P.14
Aird, W.C.15
-
23
-
-
0026052725
-
Cloning of the human gene for intercellular adhesion molecule 1 and analysis of its 5′-regulatory region. Induction by cytokines and phorbol ester
-
Voraberger, G., Schäfer, R., and Stratowa, C. (1991) Cloning of the human gene for intercellular adhesion molecule 1 and analysis of its 5′-regulatory region. Induction by cytokines and phorbol ester. J. Immunol. 147, 2777-2786
-
(1991)
J. Immunol.
, vol.147
, pp. 2777-2786
-
-
Voraberger, G.1
Schäfer, R.2
Stratowa, C.3
-
24
-
-
0028978703
-
2and tumor necrosis factor-α activate intercellular adhesion molecule 1 (ICAM-1) gene transcription through distinct cis-regulatory elements within the ICAM-1 promoter
-
2 and tumor necrosis factor-α activate intercellular adhesion molecule 1 (ICAM-1) gene transcription through distinct cis-regulatory elements within the ICAM-1 promoter. J. Biol. Chem. 270, 18966-18974
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 18966-18974
-
-
Roebuck, K.A.1
Rahman, A.2
Lakshminarayanan, V.3
Janakidevi, K.4
Malik, A.B.5
-
25
-
-
0032560071
-
The transcription of the intercellular adhesion molecule-1 is regulated by Ets transcription factors
-
de Launoit, Y., Audette, M., Pelczar, H., Plaza, S., and Baert, J. L. (1998) The transcription of the intercellular adhesion molecule-1 is regulated by Ets transcription factors. Oncogene 16, 2065-2073 (Pubitemid 28211681)
-
(1998)
Oncogene
, vol.16
, Issue.16
, pp. 2065-2073
-
-
De Launoit, Y.1
Audette, M.2
Pelczar, H.3
Plaza, S.4
Baert, J.-L.5
-
26
-
-
74549168594
-
Functional cooperation between Stat-1 and ets-1 to optimize icam-1 gene transcription
-
Yockell-Lelièvre, J., Spriet, C., Cantin, P., Malenfant, P., Heliot, L., de Launoit, Y., and Audette, M. (2009) Functional cooperation between Stat-1 and ets-1 to optimize icam-1 gene transcription. Biochem. Cell Biol. 87, 905-918
-
(2009)
Biochem. Cell Biol.
, vol.87
, pp. 905-918
-
-
Yockell-Lelièvre, J.1
Spriet, C.2
Cantin, P.3
Malenfant, P.4
Heliot, L.5
De Launoit, Y.6
Audette, M.7
-
27
-
-
0038621380
-
FEV acts as a transcriptional repressor through its DNA-binding ETS domain and alanine-rich domain
-
Maurer, P., T'Sas, F., Coutte, L., Callens, N., Brenner, C., Van Lint, C., de Launoit, Y., and Baert, J. L. (2003) FEV acts as a transcriptional repressor through its DNA-binding ETS domain and alanine-rich domain. Oncogene 22, 3319-3329
-
(2003)
Oncogene
, vol.22
, pp. 3319-3329
-
-
Maurer, P.1
T'Sas, F.2
Coutte, L.3
Callens, N.4
Brenner, C.5
Van Lint, C.6
De Launoit, Y.7
Baert, J.L.8
-
28
-
-
77954954652
-
Genome-wide analysis of ETS family DNAbinding in vitro and in vivo
-
Wei, G. H., Badis, G., Berger, M. F., Kivioja, T., Palin, K., Enge, M., Bonke, M., Jolma, A., Varjosalo, M., Gehrke, A. R., Yan, J., Talukder, S., Turunen, M., Taipale, M., Stunnenberg, H. G., Ukkonen, E., Hughes, T. R., Bulyk, M. L., and Taipale, J. (2010) Genome-wide analysis of ETS family DNAbinding in vitro and in vivo. EMBO J. 29, 2147-2160
-
(2010)
EMBO J.
, vol.29
, pp. 2147-2160
-
-
Wei, G.H.1
Badis, G.2
Berger, M.F.3
Kivioja, T.4
Palin, K.5
Enge, M.6
Bonke, M.7
Jolma, A.8
Varjosalo, M.9
Gehrke, A.R.10
Yan, J.11
Talukder, S.12
Turunen, M.13
Taipale, M.14
Stunnenberg, H.G.15
Ukkonen, E.16
Hughes, T.R.17
Bulyk, M.L.18
Taipale, J.19
-
29
-
-
77957348625
-
Combinatorial transcriptional control in blood stem/progenitor cells. Genome-wide analysis of 10 major transcriptional regulators
-
Wilson, N. K., Foster, S. D., Wang, X., Knezevic, K., Schütte, J., Kaimakis, P., Chilarska, P. M., Kinston, S., Ouwehand, W. H., Dzierzak, E., Pimanda, J. E., de Bruijn, M. F., and Göttgens, B. (2010) Combinatorial transcriptional control in blood stem/progenitor cells. Genome-wide analysis of 10 major transcriptional regulators. Cell Stem Cell 7, 532-544
-
(2010)
Cell Stem Cell
, vol.7
, pp. 532-544
-
-
Wilson, N.K.1
Foster, S.D.2
Wang, X.3
Knezevic, K.4
Schütte, J.5
Kaimakis, P.6
Chilarska, P.M.7
Kinston, S.8
Ouwehand, W.H.9
Dzierzak, E.10
Pimanda, J.E.11
De Bruijn, M.F.12
Göttgens, B.13
-
30
-
-
0028073850
-
Regulatory elements and transcription factors controlling basal and cytokine-induced expression of the gene encoding intercellular adhesion molecule 1
-
DOI 10.1073/pnas.91.24.11641
-
Hou, J., Baichwal, V., and Cao, Z. (1994) Regulatory elements and transcription factors controlling basal and cytokine-induced expression of the gene encoding intercellular adhesion molecule 1. Proc. Natl. Acad. Sci. U.S.A. 91, 11641-11645 (Pubitemid 24356400)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.24
, pp. 11641-11645
-
-
Hou, J.1
Baichwal, V.2
Cao, Z.3
-
31
-
-
47749121067
-
Activation of p300 histone acetyltransferase activity is an early endothelial response to laminar shear stress and is essential for stimulation of endothelial nitric-oxide synthase mRNA transcription
-
Chen, W., Bacanamwo, M., and Harrison, D. G. (2008) Activation of p300 histone acetyltransferase activity is an early endothelial response to laminar shear stress and is essential for stimulation of endothelial nitric-oxide synthase mRNA transcription. J. Biol. Chem. 283, 16293-16298
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 16293-16298
-
-
Chen, W.1
Bacanamwo, M.2
Harrison, D.G.3
-
32
-
-
30444436766
-
The principal eosinophil peroxidase product, HOSCN, is a uniquely potent phagocyte oxidant inducer of endothelial cell tissue factor activity
-
Wang, J. G., Mahmud, S. A., Thompson, J. A., Geng, J. G., Key, N. S., and Slungaard, A. (2006) The principal eosinophil peroxidase product, HOSCN, is a uniquely potent phagocyte oxidant inducer of endothelial cell tissue factor activity. A potential mechanism for thrombosis in eosinophilic inflammatory states. Blood 107, 558-565
-
(2006)
A Potential Mechanism for Thrombosis in Eosinophilic Inflammatory States. Blood
, vol.107
, pp. 558-565
-
-
Wang, J.G.1
Mahmud, S.A.2
Thompson, J.A.3
Geng, J.G.4
Key, N.S.5
Slungaard, A.6
-
33
-
-
0029155736
-
Regulation of the human P-selectin promoter by Bcl-3 and specific homodimeric members of the NF-κB/Rel family
-
Pan, J., and McEver, R. P. (1995) Regulation of the human P-selectin promoter by Bcl-3 and specific homodimeric members of the NF-κB/Rel family. J. Biol. Chem. 270, 23077-23083
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 23077-23083
-
-
Pan, J.1
McEver, R.P.2
-
34
-
-
67649503016
-
NF-κB regulates thrombin-induced ICAM-1 gene expression in cooperation with NFAT by binding to the intronic NF-κB site in the ICAM-1 gene
-
Xue, J., Thippegowda, P. B., Hu, G., Bachmaier, K., Christman, J. W., Malik, A. B., and Tiruppathi, C. (2009) NF-κB regulates thrombin-induced ICAM-1 gene expression in cooperation with NFAT by binding to the intronic NF-κB site in the ICAM-1 gene. Physiol. Genomics 38, 42-53
-
(2009)
Physiol. Genomics
, vol.38
, pp. 42-53
-
-
Xue, J.1
Thippegowda, P.B.2
Hu, G.3
Bachmaier, K.4
Christman, J.W.5
Malik, A.B.6
Tiruppathi, C.7
-
35
-
-
0030772376
-
Novel inhibitors of cytokine-induced IκBα phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo
-
DOI 10.1074/jbc.272.34.21096
-
Pierce, J. W., Schoenleber, R., Jesmok, G., Best, J., Moore, S. A., Collins, T., and Gerritsen, M. E. (1997) Novel inhibitors of cytokine-induced IκBαphosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo. J. Biol. Chem. 272, 21096-21103 (Pubitemid 27373968)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.34
, pp. 21096-21103
-
-
Pierce, J.W.1
Schoenleber, R.2
Jesmok, G.3
Best, J.4
Moore, S.A.5
Collins, T.6
Gerritsen, M.E.7
-
36
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
DOI 10.1073/pnas.0506580102
-
Subramanian, A., Tamayo, P., Mootha, V. K., Mukherjee, S., Ebert, B. L., Gillette, M. A., Paulovich, A., Pomeroy, S. L., Golub, T. R., Lander, E. S., and Mesirov, J. P. (2005) Gene set enrichment analysis. A knowledgebased approach for interpreting genome-wide expression profiles. Proc. Natl. Acad. Sci. U.S.A. 102, 15545-15550 (Pubitemid 41528093)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.43
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
Mukherjee, S.4
Ebert, B.L.5
Gillette, M.A.6
Paulovich, A.7
Pomeroy, S.L.8
Golub, T.R.9
Lander, E.S.10
Mesirov, J.P.11
-
37
-
-
36549027355
-
GSEA-P: A desktop application for gene set enrichment analysis
-
DOI 10.1093/bioinformatics/btm369
-
Subramanian, A., Kuehn, H., Gould, J., Tamayo, P., and Mesirov, J. P. (2007) GSEA-P, a desktop application for Gene Set Enrichment Analysis. Bioinformatics 23, 3251-3253 (Pubitemid 350187532)
-
(2007)
Bioinformatics
, vol.23
, Issue.23
, pp. 3251-3253
-
-
Subramanian, A.1
Kuehn, H.2
Gould, J.3
Tamayo, P.4
Mesirov, J.P.5
-
38
-
-
0038054341
-
PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
DOI 10.1038/ng1180
-
Mootha, V. K., Lindgren, C. M., Eriksson, K. F., Subramanian, A., Sihag, S., Lehar, J., Puigserver, P., Carlsson, E., Ridderstråle, M., Laurila, E., Houstis, N., Daly, M. J., Patterson, N., Mesirov, J. P., Golub, T. R., Tamayo, P., Spiegelman, B., Lander, E. S., Hirschhorn, J. N., Altshuler, D., and Groop, L. C. (2003) PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately down-regulated in human diabetes. Nat. Genet. 34, 267-273 (Pubitemid 36792858)
-
(2003)
Nature Genetics
, vol.34
, Issue.3
, pp. 267-273
-
-
Mootha, V.K.1
Lindgren, C.M.2
Eriksson, K.-F.3
Subramanian, A.4
Sihag, S.5
Lehar, J.6
Puigserver, P.7
Carlsson, E.8
Ridderstrale, M.9
Laurila, E.10
Houstis, N.11
Daly, M.J.12
Patterson, N.13
Mesirov, J.P.14
Golub, T.R.15
Tamayo, P.16
Spiegelman, B.17
Lander, E.S.18
Hirschhorn, J.N.19
Altshuler, D.20
Groop, L.C.21
more..
-
39
-
-
0034921965
-
Expression, regulation, and function of inhibitor of apoptosis family genes in rat mesangial cells
-
DOI 10.1046/j.1523-1755.2001.060002579.x
-
Furusu, A., Nakayama, K., Xu, Q., Konta, T., Sugiyama, H., and Kitamura, M. (2001) Expression, regulation, and function of inhibitor of apoptosis family genes in rat mesangial cells. Kidney Int. 60, 579-586 (Pubitemid 32678901)
-
(2001)
Kidney International
, vol.60
, Issue.2
, pp. 579-586
-
-
Furusu, A.1
Nakayama, K.2
Xu, Q.3
Konta, T.4
Sugiyama, H.5
Kitamura, M.6
-
40
-
-
0024512985
-
Endothelial cell gene expression of a neutrophil chemotactic factor by TNF-α, LPS, and IL-1α
-
Strieter, R. M., Kunkel, S. L., Showell, H. J., Remick, D. G., Phan, S. H., Ward, P. A., and Marks, R. M. (1989) Endothelial cell gene expression of a neutrophil chemotactic factor by TNF-α, LPS, and IL-1α. Science 243, 1467-1469 (Pubitemid 19087129)
-
(1989)
Science
, vol.243
, Issue.4897
, pp. 1467-1469
-
-
Strieter, R.M.1
Kunkel, S.L.2
Showell, H.J.3
Remick, D.G.4
Phan, S.H.5
Ward, P.A.6
Marks, R.M.7
-
41
-
-
77956496365
-
Transcriptional repression. Conserved and evolved features
-
Payankaulam, S., Li, L. M., and Arnosti, D. N. (2010) Transcriptional repression. Conserved and evolved features. Curr. Biol. 20, R764-R771
-
(2010)
Curr. Biol.
, vol.20
-
-
Payankaulam, S.1
Li, L.M.2
Arnosti, D.N.3
-
42
-
-
0037012042
-
Molecular cloning of ESET, a novel histone H3-specific methyltransferase that interacts with ERG transcription factor
-
DOI 10.1038/sj.onc.1204998
-
Yang, L., Xia, L., Wu, D. Y., Wang, H., Chansky, H. A., Schubach, W. H., Hickstein, D. D., and Zhang, Y. (2002) Molecular cloning of ESET, a novel histone H3-specific methyltransferase that interacts with ERG transcription factor. Oncogene 21, 148-152 (Pubitemid 34076387)
-
(2002)
Oncogene
, vol.21
, Issue.1
, pp. 148-152
-
-
Yang, L.1
Xia, L.2
Wu, D.Y.3
Wang, H.4
Chansky, H.A.5
Schubach, W.H.6
Hickstein, D.D.7
Zhang, Y.8
-
43
-
-
0037328157
-
An ERG (ets-related gene)-associated histone methyltransferase interacts with histone deacetylases 1/2 and transcription co-repressors mSin3A/B
-
DOI 10.1042/BJ20020854
-
Yang, L., Mei, Q., Zielinska-Kwiatkowska, A., Matsui, Y., Blackburn, M. L., Benedetti, D., Krumm, A. A., Taborsky, G. J., Jr., and Chansky, H. A. (2003) An ERG (ets-related gene)-associated histone methyltransferase interacts with histone deacetylases 1/2 and transcription co-repressors mSin3A/B. Biochem. J. 369, 651-657 (Pubitemid 36246249)
-
(2003)
Biochemical Journal
, vol.369
, Issue.3
, pp. 651-657
-
-
Yang, L.1
Mei, Q.2
Zielinska-Kwiatkowska, A.3
Matsui, Y.4
Blackburn, M.L.5
Benedetti, D.6
Krumm, A.A.7
Taborsky Jr., G.J.8
Chansky, H.A.9
-
44
-
-
57149148250
-
Combinatorial regulation of endothelial gene expression by Ets and Forkhead transcription factors
-
De Val, S., Chi, N. C., Meadows, S. M., Minovitsky, S., Anderson, J. P., Harris, I. S., Ehlers, M. L., Agarwal, P., Visel, A., Xu, S. M., Pennacchio, L. A., Dubchak, I., Krieg, P. A., Stainier, D. Y., and Black, B. L. (2008) Combinatorial regulation of endothelial gene expression by Ets and Forkhead transcription factors. Cell 135, 1053-1064
-
(2008)
Cell
, vol.135
, pp. 1053-1064
-
-
De Val, S.1
Chi, N.C.2
Meadows, S.M.3
Minovitsky, S.4
Anderson, J.P.5
Harris, I.S.6
Ehlers, M.L.7
Agarwal, P.8
Visel, A.9
Xu, S.M.10
Pennacchio, L.A.11
Dubchak, I.12
Krieg, P.A.13
Stainier, D.Y.14
Black, B.L.15
-
45
-
-
0348049997
-
Ets ternary complex transcription factors
-
DOI 10.1016/j.gene.2003.09.028
-
Buchwalter, G., Gross, C., and Wasylyk, B. (2004) Ets ternary complex transcription factors. Gene 324, 1-14 (Pubitemid 38030321)
-
(2004)
Gene
, vol.324
, Issue.1-2
, pp. 1-14
-
-
Buchwalter, G.1
Gross, C.2
Wasylyk, B.3
-
46
-
-
0032103332
-
Ets transcription factors: Nuclear effectors of the Ras-MAP-kinase signaling pathway
-
DOI 10.1016/S0968-0004(98)01211-0
-
Wasylyk, B., Hagman, J., and Gutierrez-Hartmann, A. (1998) Ets transcription factors. Nuclear effectors of the Ras-MAP-kinase signaling pathway. Trends Biochem. Sci. 23, 213-216 (Pubitemid 28302618)
-
(1998)
Trends in Biochemical Sciences
, vol.23
, Issue.6
, pp. 213-216
-
-
Wasylyk, B.1
Hagman, J.2
Gutierrez-Hartmann, A.3
-
47
-
-
0030975975
-
A new member of the ETS family fused to EWS in Ewing tumors
-
Peter, M., Couturier, J., Pacquement, H., Michon, J., Thomas, G., Magdelenat, H., and Delattre, O. (1997) A new member of the ETS family fused to EWS in Ewing tumors. Oncogene 14, 1159-1164 (Pubitemid 27141917)
-
(1997)
Oncogene
, vol.14
, Issue.10
, pp. 1159-1164
-
-
Peter, M.1
Couturier, J.2
Pacquement, H.3
Michon, J.4
Thomas, G.5
Magdelenat, H.6
Delattre, O.7
-
48
-
-
0032565916
-
Erg proteins, transcription factors of the Ets family, form homo, heterodimers and ternary complexes via two distinct domains
-
Carrère, S., Verger, A., Flourens, A., Stehelin, D., and Duterque-Coquillaud, M. (1998) Erg proteins, transcription factors of the Ets family, form homo-, heterodimers, and ternary complexes via two distinct domains. Oncogene 16, 3261-3268 (Pubitemid 28330424)
-
(1998)
Oncogene
, vol.16
, Issue.25
, pp. 3261-3268
-
-
Carrere, S.1
Verger, A.2
Flourens, A.3
Stehelin, D.4
Duterque-Coquillaud, M.5
-
49
-
-
0027486297
-
Molecular regulation of the human IL-3 gene: Inducible T cell-restricted expression requires intact AP-1 and Elf-1 nuclear protein binding sites
-
DOI 10.1084/jem.178.5.1681
-
Gottschalk, L. R., Giannola, D. M., and Emerson, S. G. (1993) Molecular regulation of the human IL-3 gene. Inducible T cell-restricted expression requires intact AP-1 and Elf-1 nuclear protein binding sites. J. Exp. Med. 178, 1681-1692 (Pubitemid 23318447)
-
(1993)
Journal of Experimental Medicine
, vol.178
, Issue.5
, pp. 1681-1692
-
-
Gottschalk, L.R.1
Giannola, D.M.2
Emerson, S.G.3
-
50
-
-
0030610692
-
ETS1, NFκB and AP1 synergistically transactivate the human GM-CSF promoter
-
DOI 10.1038/sj.onc.1201125
-
Thomas, R. S., Tymms, M. J., McKinlay, L. H., Shannon, M. F., Seth, A., and Kola, I. (1997) ETS1, NFκB, and AP1 synergistically transactivate the human GM-CSF promoter. Oncogene 14, 2845-2855 (Pubitemid 27313417)
-
(1997)
Oncogene
, vol.14
, Issue.23
, pp. 2845-2855
-
-
Thomas, R.S.1
Tymms, M.J.2
McKinlay, L.H.3
Shannon, M.F.4
Seth, A.5
Kola, I.6
-
51
-
-
0032513227
-
Synergistic regulation of the human interleukin-12 p40 promoter by NFκB and Ets transcription factors in Epstein-Barr virus-transformed B cells and macrophages
-
DOI 10.1074/jbc.273.11.6431
-
Gri, G., Savio, D., Trinchieri, G., and Ma, X. (1998) Synergistic regulation of the human interleukin-12 p40 promoter by NFκB and Ets transcription factors in Epstein-Barr virus-transformed B cells and macrophages. J. Biol. Chem. 273, 6431-6438 (Pubitemid 28144737)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.11
, pp. 6431-6438
-
-
Gri, G.1
Savio, D.2
Trinchieri, G.3
Ma, X.4
-
52
-
-
0028889159
-
Regulation of cell type-specific interleukin-2 receptor α-chain gene expression. Potential role of physical interactions between Elf-1, HMG-I(Y), and NF-κB family proteins
-
John, S., Reeves, R. B., Lin, J. X., Child, R., Leiden, J. M., Thompson, C. B., and Leonard, W. J. (1995) Regulation of cell type-specific interleukin-2 receptor α-chain gene expression. Potential role of physical interactions between Elf-1, HMG-I(Y), and NF-κB family proteins. Mol. Cell. Biol. 15, 1786-1796
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 1786-1796
-
-
John, S.1
Reeves, R.B.2
Lin, J.X.3
Child, R.4
Leiden, J.M.5
Thompson, C.B.6
Leonard, W.J.7
-
53
-
-
33750585729
-
Hypertension accelerated experimental abdominal aortic aneurysm through upregulation of nuclear factor κB and ets
-
DOI 10.1161/01.HYP.0000240266.26185.57, PII 0000426820061000000022
-
Shiraya, S., Miwa, K., Aoki, M., Miyake, T., Oishi, M., Kataoka, K., Ohgi, S., Ogihara, T., Kaneda, Y., and Morishita, R. (2006) Hypertension accelerated experimental abdominal aortic aneurysm through up-regulation of nuclear factor κB and Ets. Hypertension 48, 628-636 (Pubitemid 44843866)
-
(2006)
Hypertension
, vol.48
, Issue.4
, pp. 628-636
-
-
Shiraya, S.1
Miwa, K.2
Aoki, M.3
Miyake, T.4
Oishi, M.5
Kataoka, K.6
Ohgi, S.7
Ogihara, T.8
Kaneda, Y.9
Morishita, R.10
-
54
-
-
0034740115
-
TNFα induces expression of transcription factors c-fos, Egr-1, and Ets-1 in vascular lesions through extracellular signal-regulated kinases 1/2
-
DOI 10.1016/S0021-9150(01)00497-X, PII S002191500100497X
-
Goetze, S., Kintscher, U., Kaneshiro, K., Meehan, W. P., Collins, A., Fleck, E., Hsueh, W. A., and Law, R. E. (2001) TNFα induces expression of transcription factors c-fos, Egr-1, and Ets-1 in vascular lesions through extracellular signal-regulated kinases 1/2. Atherosclerosis 159, 93-101 (Pubitemid 33016626)
-
(2001)
Atherosclerosis
, vol.159
, Issue.1
, pp. 93-101
-
-
Goetze, S.1
Kintscher, U.2
Kaneshiro, K.3
Meehan, W.P.4
Collins, A.5
Fleck, E.6
Hsueh, W.A.7
Law, R.E.8
-
55
-
-
0029869801
-
Regulated expression of the Ets-1 transcription factor in vascular smooth muscle cells in vivo and in vitro
-
Hultgårdh-Nilsson, A., Cercek, B., Wang, J. W., Naito, S., Lövdahl, C., Sharifi, B., Forrester, J. S., and Fagin, J. A. (1996) Regulated expression of the ets-1 transcription factor in vascular smooth muscle cells in vivo and in vitro. Circ. Res. 78, 589-595 (Pubitemid 26106874)
-
(1996)
Circulation Research
, vol.78
, Issue.4
, pp. 589-595
-
-
Hultgardh-Nilsson, A.1
Cercek, B.2
Wang, J.-W.3
Naito, S.4
Lovdahl, C.5
Sharifi, B.6
Forrester, J.S.7
Fagin, J.A.8
-
56
-
-
80051791690
-
Ets2 determines the inflammatory state of endothelial cells in advanced atherosclerotic lesions
-
Cheng, C., Tempel, D., Den Dekker, W. K., Haasdijk, R., Chrifi, I., Bos, F. L., Wagtmans, K., van de Kamp, E. H., Blonden, L., Biessen, E. A., Moll, F., Pasterkamp, G., Serruys, P. W., Schulte-Merker, S., and Duckers, H. J. (2011) Ets2 determines the inflammatory state of endothelial cells in advanced atherosclerotic lesions. Circ. Res. 109, 382-395
-
(2011)
Circ. Res.
, vol.109
, pp. 382-395
-
-
Cheng, C.1
Tempel, D.2
Den Dekker, W.K.3
Haasdijk, R.4
Chrifi, I.5
Bos, F.L.6
Wagtmans, K.7
Van De Kamp, E.H.8
Blonden, L.9
Biessen, E.A.10
Moll, F.11
Pasterkamp, G.12
Serruys, P.W.13
Schulte-Merker, S.14
Duckers, H.J.15
-
57
-
-
0035092527
-
Overexpression of transcription factor Ets-1 in rheumatoid arthritis synovial membrane: Regulation of expression and activation by interleukin-1 and tumor necrosis factor α
-
DOI 10.1002/1529-0131(200102)44:2<266::AID-ANR43>3.0.CO;2-G
-
Redlich, K., Kiener, H. P., Schett, G., Tohidast-Akrad, M., Selzer, E., Radda, I., Stummvoll, G. H., Steiner, C. W., Gröger, M., Bitzan, P., Zenz, P., Smolen, J. S., and Steiner, G. (2001) Overexpression of transcription factor Ets-1 in rheumatoid arthritis synovial membrane. Regulation of expression and activation by interleukin-1 and tumor necrosis factor α. Arthritis Rheum. 44, 266-274 (Pubitemid 32207019)
-
(2001)
Arthritis and Rheumatism
, vol.44
, Issue.2
, pp. 266-274
-
-
Redlich, K.1
Kiener, H.P.2
Schett, G.3
Tohidast-Akrad, M.4
Selzer, E.5
Radda, I.6
Stummvoll, G.H.7
Steiner, C.W.8
Groger, M.9
Bitzan, P.10
Zenz, P.11
Smolen, J.S.12
Steiner, G.13
-
58
-
-
0035793609
-
ESE-1 is a novel transcriptional mediator of inflammation that interacts with NF-κB to regulate the inducible nitric-oxide synthase gene
-
Rudders, S., Gaspar, J., Madore, R., Voland, C., Grall, F., Patel, A., Pellacani, A., Perrella, M. A., Libermann, T. A., and Oettgen, P. (2001) ESE-1 is a novel transcriptional mediator of inflammation that interacts with NF-κB to regulate the inducible nitric-oxide synthase gene. J. Biol. Chem. 276, 3302-3309
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3302-3309
-
-
Rudders, S.1
Gaspar, J.2
Madore, R.3
Voland, C.4
Grall, F.5
Patel, A.6
Pellacani, A.7
Perrella, M.A.8
Libermann, T.A.9
Oettgen, P.10
-
59
-
-
0037653338
-
Responses to the proinflammatory cytokines interleukin-1 and tumor necrosis factor α in cells derived from rheumatoid synovium and other joint tissues involve nuclear factor κB-mediated induction of the Ets transcription factor ESE-1
-
DOI 10.1002/art.10942
-
Grall, F., Gu, X., Tan, L., Cho, J. Y., Inan, M. S., Pettit, A. R., Thamrongsak, U., Choy, B. K., Manning, C., Akbarali, Y., Zerbini, L., Rudders, S., Goldring, S. R., Gravallese, E. M., Oettgen, P., Goldring, M. B., and Libermann, T. A. (2003) Responses to the proinflammatory cytokines interleukin- 1 and tumor necrosis factor α in cells derived from rheumatoid synovium and other joint tissues involve nuclear factor κB-mediated induction of the Ets transcription factor ESE-1. Arthritis Rheum. 48, 1249-1260 (Pubitemid 36554524)
-
(2003)
Arthritis and Rheumatism
, vol.48
, Issue.5
, pp. 1249-1260
-
-
Grall, F.1
Gu, X.2
Tan, L.3
Cho, J.-Y.4
Inan, M.S.5
Pettit, A.R.6
Thamrongsak, U.7
Choy, B.K.8
Manning, C.9
Akbarali, Y.10
Zerbini, L.11
Rudders, S.12
Goldring, S.R.13
Gravallese, E.M.14
Oettgen, P.15
Goldring, M.B.16
Libermann, T.A.17
|