Astragalus extract alleviates nerve injury after cerebral ischemia by improving energy metabolism and inhibiting apoptosis

Biological and Pharmaceutical Bulletin

Volumn 35, Issue 4, 2012, Pages 449-454

  Huang, Xiao Ping ^a   Tan, Hua ^a   Chen, Bei Yang ^a   Deng, Chang Qing ^a  

^a HUNAN UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Apoptosis; Astragalus extract; Cerebral ischemia reperfusion injury; Cytochrome c; Energy metabolism; Phosphorylated c Jun N terminal kinase1 2

Indexed keywords

ADENINE NUCLEOTIDE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATE; ASTRAGALUS EXTRACT; CASPASE 3; CASPASE 9; CYTOCHROME C; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE KINASE 7; NORPHENAZONE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTRAGALUS MEMBRANACEUS; BRAIN DAMAGE; BRAIN ISCHEMIA; BRAIN NERVE CELL; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENERGY; ENERGY CHARGE; ENERGY METABOLISM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HIPPOCAMPAL CA1 REGION; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; PROTEIN EXPRESSION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; SURVIVAL RATE;

ANIMALS; APOPTOSIS; ASTRAGALUS PLANT; BRAIN ISCHEMIA; CA1 REGION, HIPPOCAMPAL; CASPASE 3; CASPASE 9; CYTOCHROMES C; ENERGY METABOLISM; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MICE; MICE, INBRED C57BL; NEURONS; NEUROPROTECTIVE AGENTS; PLANT EXTRACTS; REPERFUSION INJURY;

EID: 84859476821     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.35.449     Document Type: Article

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