Neuroprotective effects of astragulus membranaceus on hypoxia-ischemia brain damage in neonatal rat hippocampus

Zhongguo Zhongyao Zazhi

Volumn 28, Issue 12, 2003, Pages 1177-

  Jia, Rui Zhe ^a   Jiang, Li ^a   Qiao, Li Xing ^a   Chen, Ping Sheng ^a  

^a SOUTHEAST UNIVERSITY   (China)

Author keywords

Apoptosis; Astragulus membraneaceus; Caspase; Cerebral anoxia; Cerebral ischemia

Indexed keywords

CASP3 PROTEIN, RAT; CASPASE; CASPASE 3; HERBACEOUS AGENT; MESSENGER RNA; NEUROPROTECTIVE AGENT;

ANIMAL; APOPTOSIS; ARTICLE; ASTRAGALUS MEMBRANACEUS; BIOSYNTHESIS; BRAIN ISCHEMIA; CELL DEATH; CHEMISTRY; DISCRIMINATION LEARNING; DRUG EFFECT; ENZYMOLOGY; FEMALE; GENETICS; HIPPOCAMPUS; ISOLATION AND PURIFICATION; MALE; NERVE CELL; NEWBORN; PATHOLOGY; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; ASTRAGALUS MEMBRANACEUS; CASPASE 3; CASPASES; CELL DEATH; DISCRIMINATION LEARNING; DRUGS, CHINESE HERBAL; FEMALE; HIPPOCAMPUS; HYPOXIA-ISCHEMIA, BRAIN; MALE; NEURONS; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

EID: 24644458123     PISSN: 10015302     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Nakajima W, Ishida A, Lange M S. Apoptosis Has a Prolongde Role in the Neurodegeneration after Hypoxic Ischemia in the Newborn Rat. J Neurosci, 2000, 20(21): 7994.
2. Ikeda T, Mishima K, Yoshikama K, et al. Selective and long-term learning impairment following neonatal hypoxic-ischemic brain insult in rats. Behav Brain Res, 2001, 118: 17.
3. Adachi M, Sohma O, Tsuneishi S, et al. Combination Effect of Systemic Hypothermia and Caspase Inhibitor Administration against Hypoxic-Ischemic Brain Damage in Neonatal Rats. Pediatr Res, 2001, 50(5): 590.
4. Rice J E, Vannucci R C, Brierley J B. The Influence of Immaturity on Hypoxic-ischemic Brain Damage in the Rat. Ann Neurol, 1981, 9: 131.
5. Towfighi J, Mauger D. Temporal Evolution of Neuronal Changes in Cerebral Hypoxia-ischemia in Developing Rats: A Qualitative Light Microscopic Study. Dev Brain Res, 1998, 109: 169.
6. Jiang L, Ding Y J and Tang Y Z. Relationship Between the Expression of c-fos Gene and Delayed Neuronal Death in Rat Neonatal Hippocampus Following Hypoxic-ischemic Insult. Chin Med J. 2001, 114(5): 520.
7. Harrison D C, Davis R P, Bond B C, et al. Caspase mRNA Expression in A Rat Model of Focal Cerebral Ischemia. Mol Brain Res, 2001, 89: 133.