메뉴 건너뛰기




Volumn 3, Issue 6, 2012, Pages 1263-1267

Berberine sensitizes mutliple human cancer cells to the anticancer effects of doxorubicin in vitro

Author keywords

A549; Berberine; Doxorubicin; HeLa; Synergistic effect

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ACRIDINE; BERBERINE; DOXORUBICIN;

EID: 84859464708     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2012.644     Document Type: Article
Times cited : (80)

References (29)
  • 2
    • 33748764139 scopus 로고    scopus 로고
    • Doxorubicin in experimental and clinical heart failure
    • Christiansen S and Autschbach R: Doxorubicin in experimental and clinical heart failure. Eur J Cardiothorac Surg 30: 611-616, 2006.
    • (2006) Eur J Cardiothorac Surg , vol.30 , pp. 611-616
    • Christiansen, S.1    Autschbach, R.2
  • 3
    • 0030962254 scopus 로고    scopus 로고
    • Relationship between lethal effects and topoisomerase II mediated double-strand DNA breaks produced by anthracyclines with different sequence specificity
    • Binaschi M, Capranico G, Dal Bo L and Zunino F: Relationship between lethal effects and topoisomerase II mediated double-strand DNA breaks produced by anthracyclines with different sequence specificity. Mol Pharmacol 51: 1053-1059, 1997.
    • (1997) Mol Pharmacol , vol.51 , pp. 1053-1059
    • Binaschi, M.1    Capranico, G.2    Dal Bo, L.3    Zunino, F.4
  • 4
    • 0023697180 scopus 로고
    • Kinetochore immunofluorescence in micronuclei: A rapid method for the in situ detection of aneuploidy and chromosome breakage in human fibroblasts
    • Hennig UG, Rudd NL and Hoar DI: Kinetochore immunofluorescence in micronuclei: a rapid method for the in situ detection of aneuploidy and chromosome breakage in human fibroblasts. Mutat Res 203: 405-414, 1988.
    • (1988) Mutat Res , vol.203 , pp. 405-414
    • Hennig, U.G.1    Rudd, N.L.2    Hoar, D.I.3
  • 6
    • 0020684494 scopus 로고
    • Effect of anthracyline antibiotics on oxygen radical formation in rat heart
    • Doroshow JH: Effect of anthracyline antibiotics on oxygen radical formation in rat heart. Cancer Res 43: 460-472, 1983.
    • (1983) Cancer Res , vol.43 , pp. 460-472
    • Doroshow, J.H.1
  • 8
    • 0030612062 scopus 로고    scopus 로고
    • Ca2+ overloading causes the negative inotropic effect of doxorubicin in myocytes isolated from guinea-pig hearts
    • Temma K, Chugun A, Akera T, Hara Y, Sasaki T and Kondo H: Ca2+ overloading causes the negative inotropic effect of doxorubicin in myocytes isolated from guinea-pig hearts. Eur J Pharmacol 322: 235-242, 1997.
    • (1997) Eur J Pharmacol , vol.322 , pp. 235-242
    • Temma, K.1    Chugun, A.2    Akera, T.3    Hara, Y.4    Sasaki, T.5    Kondo, H.6
  • 9
    • 0002258030 scopus 로고    scopus 로고
    • Berberine: Therapeutic potential of an alkaloid found in several medicinal plants
    • Timothy CB and Gregory SK: Berberine: therapeutic potential of an alkaloid found in several medicinal plants. Altern Med Rev 2: 94-102, 1997.
    • (1997) Altern Med Rev , vol.2 , pp. 94-102
    • Timothy, C.B.1    Gregory, S.K.2
  • 10
    • 0027213657 scopus 로고
    • Pharmacological studies on antidiarrheal effects of berberine and geranii herb
    • In Japanese
    • Takase H, Yamamoto K, Ito K and Yumioka E: Pharmacological studies on antidiarrheal effects of berberine and geranii herb. Nihon Yakurigaku Zasshi 102: 101-112, 1993 (In Japanese).
    • (1993) Nihon Yakurigaku Zasshi , vol.102 , pp. 101-112
    • Takase, H.1    Yamamoto, K.2    Ito, K.3    Yumioka, E.4
  • 12
    • 74049139484 scopus 로고    scopus 로고
    • Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression
    • Zhang H, Wei J, Xue R, et al: Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression. Metabolism 59: 285-292, 2010.
    • (2010) Metabolism , vol.59 , pp. 285-292
    • Zhang, H.1    Wei, J.2    Xue, R.3
  • 13
    • 54049130500 scopus 로고    scopus 로고
    • Effect of berberine on hepatocyte proliferation, inducible nitric oxide synthase expression, cytochrome P450 2E1 and 1A2 activities in diethylnitrosamine- and phenobarbital- treated rats
    • Zhao X, Zhang JJ, Wang X, Bu XY, Lou YQ and Zhang GL: Effect of berberine on hepatocyte proliferation, inducible nitric oxide synthase expression, cytochrome P450 2E1 and 1A2 activities in diethylnitrosamine- and phenobarbital- treated rats. Biomed Pharmacother 62: 567-572, 2008.
    • (2008) Biomed Pharmacother , vol.62 , pp. 567-572
    • Zhao, X.1    Zhang, J.J.2    Wang, X.3    Bu, X.Y.4    Lou, Y.Q.5    Zhang, G.L.6
  • 14
    • 0033989928 scopus 로고    scopus 로고
    • Studies on preventive and curative effects of berberine on chemical-induced hepatotoxicity in rodents
    • Janbaz KH and Gilani AH: Studies on preventive and curative effects of berberine on chemical-induced hepatotoxicity in rodents. Fitoterapia 71: 25-33, 2000.
    • (2000) Fitoterapia , vol.71 , pp. 25-33
    • Janbaz, K.H.1    Gilani, A.H.2
  • 15
    • 77949443140 scopus 로고    scopus 로고
    • Effect of berberine on Cdk9 and cyclin T1 expressions in myocardium of diabetic rats
    • Zhou JY, Zhou SW, Tang JL, Xu Y and Ying Y: Effect of berberine on Cdk9 and cyclin T1 expressions in myocardium of diabetic rats. J Med Coll PLA 23: 45-51, 2008.
    • (2008) J Med Coll PLA , vol.23 , pp. 45-51
    • Zhou, J.Y.1    Zhou, S.W.2    Tang, J.L.3    Xu, Y.4    Ying, Y.5
  • 16
    • 0037969021 scopus 로고    scopus 로고
    • Efficacy and safety of berberine for congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy
    • Zeng XH, Zeng XJ and Li YY: Efficacy and safety of berberine for congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. Am J Cardiol 92: 173-176, 2003.
    • (2003) Am J Cardiol , vol.92 , pp. 173-176
    • Zeng, X.H.1    Zeng, X.J.2    Li, Y.Y.3
  • 17
    • 79951812360 scopus 로고    scopus 로고
    • Berberine possesses muscarinic agonist-like properties in cultured rodent cardiomyocytes
    • Salehi S and Filtz TM: Berberine possesses muscarinic agonist-like properties in cultured rodent cardiomyocytes. Pharmacol Res 63: 335-340, 2011.
    • (2011) Pharmacol Res , vol.63 , pp. 335-340
    • Salehi, S.1    Filtz, T.M.2
  • 18
    • 77956190161 scopus 로고    scopus 로고
    • Berberine induces apoptosis in breast cancer cells (MCF-7) through mitochondrial-dependent pathway
    • Patil JB, Kim J and Jayaprakasha GK: Berberine induces apoptosis in breast cancer cells (MCF-7) through mitochondrial-dependent pathway. Eur J Pharmacol 645: 70-78, 2010.
    • (2010) Eur J Pharmacol , vol.645 , pp. 70-78
    • Patil, J.B.1    Kim, J.2    Jayaprakasha, G.K.3
  • 19
    • 0028814733 scopus 로고
    • Berberine complexes with DNA in the berberine-induced apoptosis in human leukemic HL-60 cells
    • Kuo CL, Chou CC and Yung BY: Berberine complexes with DNA in the berberine-induced apoptosis in human leukemic HL-60 cells. Cancer Lett 93: 193-200, 1995.
    • (1995) Cancer Lett , vol.93 , pp. 193-200
    • Kuo, C.L.1    Chou, C.C.2    Yung, B.Y.3
  • 20
    • 67649515350 scopus 로고    scopus 로고
    • Berberine inhibits Rho GTPases and cell migration at low doses but induces G2 arrest and apoptosis at high doses in human cancer cells
    • Tsang CM, Lau EP, Di K, et al: Berberine inhibits Rho GTPases and cell migration at low doses but induces G2 arrest and apoptosis at high doses in human cancer cells. Int J Mol Med 24: 131-138, 2009.
    • (2009) Int J Mol Med , vol.24 , pp. 131-138
    • Tsang, C.M.1    Lau, E.P.2    Di, K.3
  • 21
    • 77950020488 scopus 로고    scopus 로고
    • The alkaloid berberine inhibits the growth of Anoikis-resistant MCF-7 and MDA-MB-231 breast cancer cell lines by inducing cell cycle arrest
    • Kim JB, Yu JH, Ko E, et al: The alkaloid berberine inhibits the growth of Anoikis-resistant MCF-7 and MDA-MB-231 breast cancer cell lines by inducing cell cycle arrest. Phytomedicine 17: 436-440, 2010.
    • (2010) Phytomedicine , vol.17 , pp. 436-440
    • Kim, J.B.1    Yu, J.H.2    Ko, E.3
  • 22
    • 77549084786 scopus 로고    scopus 로고
    • Acute toxicity of berberine and its correlation with the blood concentration in mice
    • Kheir MM, Wang YG, Hua L, Hu J, Li LL, Lei F and Du L: Acute toxicity of berberine and its correlation with the blood concentration in mice. Food Chem Toxicol 48: 1105-1110, 2010.
    • (2010) Food Chem Toxicol , vol.48 , pp. 1105-1110
    • Kheir, M.M.1    Wang, Y.G.2    Hua, L.3    Hu, J.4    Li, L.L.5    Lei, F.6    Du, L.7
  • 23
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
    • Chou TC and Talalay P: Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv Enzyme Regul 22: 27-55, 1984.
    • (1984) Adv Enzyme Regul , vol.22 , pp. 27-55
    • Chou, T.C.1    Talalay, P.2
  • 24
    • 0034889197 scopus 로고    scopus 로고
    • Drug synergism: Its detection and applications
    • Tallarida RJ: Drug synergism: Its detection and applications. J Pharmacol Exp Ther 298: 865-872, 2001.
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 865-872
    • Tallarida, R.J.1
  • 25
    • 70349734337 scopus 로고    scopus 로고
    • Chronic doxorubicin cardiotoxicity is mediated by oxidative DNA damage-ATM-p53-apoptosis pathway and attenuated by pitavastatin through the inhibition of Rac1 activity
    • Yoshida M, Shiojima I, Ikeda H and Komuro L: Chronic doxorubicin cardiotoxicity is mediated by oxidative DNA damage-ATM-p53-apoptosis pathway and attenuated by pitavastatin through the inhibition of Rac1 activity. J Mol Cell Cardiol 47: 698-705, 2009.
    • (2009) J Mol Cell Cardiol , vol.47 , pp. 698-705
    • Yoshida, M.1    Shiojima, I.2    Ikeda, H.3    Komuro, L.4
  • 26
    • 33745001816 scopus 로고    scopus 로고
    • Inhibitory effect of berberine on the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2
    • Peng PL, Hsieh YS, Wang CJ, Hsu JL and Chou FP: Inhibitory effect of berberine on the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2. Toxicol Appl Pharmacol 214: 8-15, 2006.
    • (2006) Toxicol Appl Pharmacol , vol.214 , pp. 8-15
    • Peng, P.L.1    Hsieh, Y.S.2    Wang, C.J.3    Hsu, J.L.4    Chou, F.P.5
  • 27
    • 79956225914 scopus 로고    scopus 로고
    • Induction of G1 cell cycle arrest and apoptosis by berberine in bladder cancer cells
    • Yan K, Zhang C, Feng J, et al: Induction of G1 cell cycle arrest and apoptosis by berberine in bladder cancer cells. Eur J Pharmacol 661: 1-7, 2011.
    • (2011) Eur J Pharmacol , vol.661 , pp. 1-7
    • Yan, K.1    Zhang, C.2    Feng, J.3
  • 28
    • 42749085774 scopus 로고    scopus 로고
    • Berberine-induced apoptosis in human prostate cancer cells is initiated by reactive oxygen species generation
    • Meeran SM, Katiyar S and Katiyar SK: Berberine-induced apoptosis in human prostate cancer cells is initiated by reactive oxygen species generation. Toxicol Appl Pharmacol 229: 33-43, 2008.
    • (2008) Toxicol Appl Pharmacol , vol.229 , pp. 33-43
    • Meeran, S.M.1    Katiyar, S.2    Katiyar, S.K.3
  • 29
    • 84946384873 scopus 로고
    • The toxicity of poisons applied jointly
    • Bliss CI: The toxicity of poisons applied jointly. Ann Appl Biol 26: 585-615, 1939.
    • (1939) Ann Appl Biol , vol.26 , pp. 585-615
    • Bliss, C.I.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.