Copper(I) mediated facile synthesis of potent tubulin polymerization inhibitor, 9-amino-α-noscapine from natural α-noscapine

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 8, 2012, Pages 2983-2987

  Manchukonda, Naresh K ^a   Sridhar, Balasubramanian ^a   Naik, Pradeep K ^b   Joshi, Harish C ^c   Kantevari, Srinivas ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^b JAYPEE UNIVERSITY OF INFORMATION TECHNOLOGY   (India)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Amino noscapine; Copper iodide; Isoquinoline alkaloid; Noscapine; Tubulin polymerization

Indexed keywords

9 AMINO ALPHA NOSCAPINE; CUPROUS ION; ISOQUINOLINE ALKALOID; NOSCAPINE; PHTHALIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; DRUG STRUCTURE; DRUG SYNTHESIS; MICROTUBULE ASSEMBLY;

CATALYSIS; COPPER; MODELS, MOLECULAR; NOSCAPINE; TUBULIN MODULATORS;

EID: 84859445362     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.02.033     Document Type: Article

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