Functional alterations of large-scale brain networks related to cognitive control in obsessive-compulsive disorder

Human Brain Mapping

Volumn 33, Issue 5, 2012, Pages 1089-1106

  Cocchi, Luca ^a   Harrison, Ben J ^a,b   Pujol, Jesus ^b   Harding, Ian H ^a   Fornito, Alex ^a   Pantelis, Christos ^a   Yücel, Murat ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b Barcelona Biomedical Research Park   (Spain)

Author keywords

Arousal; FMRI; Functional connectivity; Insular cortex; Obsessive compulsive disorder

Indexed keywords

ADULT; ANXIETY; ARTICLE; BRAIN CORTEX; BRAIN FUNCTION; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; EXECUTIVE FUNCTION; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; INSULA; LIMBIC CORTEX; MALE; MULTIVARIATE ANALYSIS; NEUROIMAGING; OBSESSIVE COMPULSIVE DISORDER; PRIORITY JOURNAL; TASK PERFORMANCE;

ADOLESCENT; ADULT; BRAIN; COGNITION; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NERVE NET; OBSESSIVE-COMPULSIVE DISORDER; PSYCHOMOTOR PERFORMANCE; REACTION TIME; YOUNG ADULT;

EID: 84859439329     PISSN: 10659471     EISSN: 10970193     Source Type: Journal    
DOI: 10.1002/hbm.21270     Document Type: Article

References (106)

1. Adler CM, McDonough-Ryan P, Sax KW, Holland SK, Arndt S, Strakowski SM ( 2000): fMRI of neuronal activation with symptom provocation in unmedicated patients with obsessive compulsive disorder. J Psychiatr Res 34: 317-324.
2. Alexander GE, DeLong MR, Strick PL ( 1986): Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu Rev Neurosci 9: 357-381.
3. American Psychiatric Association (APA) ( 2000): Diagnostic and Statistical Manual of Mental Disorders. IV-TR ed. Washington D.C: American Psychiatric Association.
4. Beck AT, Steer RA, editors ( 1990): Beck Anxiety Inventory Manual. San Antonio: Psych Corp.
5. Beck AT, Rush AJ, Shaw BF, Emery G ( 1979): Cognitive Therapy of Depression. New York: Guilford.
6. Beckmann CF, DeLuca M, Devlin JT, Smith SM ( 2005): Investigations into resting-state connectivity using independent component analysis. Philos Trans R Soc Lond B Biol Sci 360: 1001-1013.
7. Biswal B, Yetkin FZ, Haughton VM, Hyde JS ( 1995): Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magn Reson Med 34: 537-541.
8. Breiter HC, Rauch SL, Kwong KK, Baker JR, Weisskoff RM, Kennedy DN, Kendrick AD, Davis TL, Jiang A, Cohen MS, Stern CE, Belliveau JW, Baer L, O'Sullivan RL, Savage CR, Jenike MA, Rosen BR ( 1996): Functional magnetic resonance imaging of symptom provocation in obsessive-compulsive disorder. Arch Gen Psychiatry 53: 595-606.
9. Bush G, Luu P, Posner MI ( 2000): Cognitive and emotional influences in anterior cingulate cortex. Trends Cogn Sci 4: 215-222.
10. Bush G, Shin LM ( 2006): The Multi-Source Interference Task: An fMRI task that reliably activates the cingulo-frontal-parietal cognitive/attention network. Nat Protoc 1: 308-313.
11. Bush G, Spencer TJ, Holmes J, Shin LM, Valera EM, Seidman LJ, Makris N, Surman C, Aleardi M, Mick E, Biederman J ( 2008): Functional magnetic resonance imaging of methylphenidate and placebo in attention-deficit/hyperactivity disorder during the multi-source interference task. Arch Gen Psychiatry 65: 102-114.
12. Calhoun VD, Adali T, Pearlson GD, Pekar JJ ( 2001): A method for making group inferences from functional MRI data using independent component analysis. Hum Brain Mapp 14: 140-151.
13. Calhoun VD, Adali T, Pekar JJ ( 2004): A method for comparing group fMRI data using independent component analysis: application to visual, motor and visuomotor tasks. Magn Reson Imaging 22: 1181-1191.
14. Calhoun VD, Kiehl KA, Pearlson GD ( 2008): Modulation of temporally coherent brain networks estimated using ICA at rest and during cognitive tasks. Hum Brain Mapp 29: 828-838.
15. Calhoun VD, Liu J, Adali T ( 2009): A review of group ICA for fMRI data and ICA for joint inference of imaging, genetic, and ERP data. Neuroimage 45( 1 Suppl): S163-S172.
16. Chamberlain SR, Fineberg NA, Blackwell AD, Robbins TW, Sahakian BJ ( 2006): Motor inhibition and cognitive flexibility in obsessive-compulsive disorder and trichotillomania. Am J Psychiatry 163: 1282-1284.
17. Chamberlain SR, Sahakian BJ ( 2007): The neuropsychiatry of impulsivity. Curr Opin Psychiatry 20: 255-261.
18. Christoff K, Gordon AM, Smallwood J, Smith R, Schooler JW ( 2009): Experience sampling during fMRI reveals default network and executive system contributions to mind wandering. Proc Natl Acad Sci USA 106: 8719-8724.
19. Corbetta M, Patel G, Shulman GL ( 2008): The reorienting system of the human brain: From environment to theory of mind. Neuron 58: 306-324.
20. Craig AD ( 2009): How do you feel-now? The anterior insula and human awareness. Nat Rev Neurosci 10: 59-70.
21. Critchley HD ( 2009): Psychophysiology of neural, cognitive and affective integration: fMRI and autonomic indicants. Int J Psychophysiol 73: 88-94.
22. Critchley HD, Wiens S, Rotshtein P, Ohman A, Dolan RJ ( 2004): Neural systems supporting interoceptive awareness. Nat Neurosci 7: 189-195.
23. Damoiseaux JS, Rombouts SA, Barkhof F, Scheltens P, Stam CJ, Smith SM, Beckmann CF ( 2006): Consistent resting-state networks across healthy subjects. Proc Natl Acad Sci USA 103: 13848-13853.
24. De Luca M, Beckmann CF, De Stefano N, Matthews PM, Smith SM ( 2006): fMRI resting state networks define distinct modes of long-distance interactions in the human brain. Neuroimage 29: 1359-1367.
25. Dosenbach NU, Fair DA, Cohen AL, Schlaggar BL, Petersen SE ( 2008): A dual-networks architecture of top-down control. Trends Cogn Sci 12: 99-105.
26. Dosenbach NU, Fair DA, Miezin FM, Cohen AL, Wenger KK, Dosenbach RA, Fox MD, Snyder AZ, Vincent JL, Raichle ME, Schlaggar BL, Petersen SE ( 2007): Distinct brain networks for adaptive and stable task control in humans. Proc Natl Acad Sci USA 104: 11073-11078.
27. Dosenbach NU, Visscher KM, Palmer ED, Miezin FM, Wenger KK, Kang HC, Burgund ED, Grimes AL, Schlaggar BL, Petersen SE ( 2006): A core system for the implementation of task sets. Neuron 50: 799-812.
28. First MB, Spitzer RL, Gibbon M, Williams JB ( 1998): Structured Clinical Interview for DSM-IV Axis 1 Disorders. Washington, D.C.: American Psychiatric Press.
29. First MB, Spitzer RL, Gibbon M, Williams JB ( 2007): Structured Clinical Interview for DSM-IV-RS Axis 1 Disorders - Non-patient edition (SCID-I/NP) New York: Biometrics Research, New York State Psychiatric Institute.
30. Fleisher AS, Sherzai A, Taylor C, Langbaum JB, Chen K, Buxton RB ( 2009): Resting-state BOLD networks versus task-associated functional MRI for distinguishing Alzheimer's disease risk groups. Neuroimage 47: 1678-1690.
31. Fox MD, Corbetta M, Snyder AZ, Vincent JL, Raichle ME ( 2006): Spontaneous neuronal activity distinguishes human dorsal and ventral attention systems. Proc Natl Acad Sci USA 103: 10046-10051.
32. Fox MD, Snyder AZ, Barch DM, Gusnard DA, Raichle ME ( 2005a): Transient BOLD responses at block transitions. Neuroimage 28: 956-966.
33. Fox MD, Snyder AZ, McAvoy MP, Barch DM, Raichle ME ( 2005b): The BOLD onset transient: Identification of novel functional differences in schizophrenia. Neuroimage 25: 771-782.
34. Friston KJ, Buechel C, Fink GR, Morris J, Rolls E, Dolan RJ ( 1997): Psychophysiological and modulatory interactions in neuroimaging. Neuroimage 6: 218-229.
35. Friston KJ, Frith CD, Liddle PF, Frackowiak RS ( 1993): Functional connectivity: the principal-component analysis of large (PET) data sets. J Cereb Blood Flow Metab 13: 5-14.
36. Friston KJ, Harrison L, Penny W ( 2003): Dynamic causal modelling. Neuroimage 19: 1273-302.
37. Goodman WK, Price LH, Rasmussen SA, Mazure C, Fleischmann RL, Hill CL, Heninger GR, Charney DS ( 1989): The Yale-Brown obsessive compulsive scale. I. Development, use, and reliability. Arch Gen Psychiatry 46: 1006-1011.
38. Graybiel AM, Rauch SL ( 2000): Toward a neurobiology of obsessive-compulsive disorder. Neuron 28: 343-347.
39. Greenberg BD, Ziemann U, Cora-Locatelli G, Harmon A, Murphy DL, Keel JC, Wassermann EM ( 2000): Altered cortical excitability in obsessive-compulsive disorder. Neurology 54: 142-147.
40. Greenberg BD, Ziemann U, Harmon A, Murphy DL, Wassermann EM ( 1998): Decreased neuronal inhibition in cerebral cortex in obsessive-compulsive disorder on transcranial magnetic stimulation. Lancet 352: 881-882.
41. Greicius MD, Krasnow B, Reiss AL, Menon V ( 2003): Functional connectivity in the resting brain: A network analysis of the default mode hypothesis. Proc Natl Acad Sci USA 100: 253-258.
42. Gu BM, Park JY, Kang DH, Lee SJ, Yoo SY, Jo HJ, Choi CH, Lee JM, Kwon JS ( 2008): Neural correlates of cognitive inflexibility during task-switching in obsessive-compulsive disorder. Brain 131( Part 1): 155-164.
43. Haber SN ( 2003): The primate basal ganglia: Parallel and integrative networks. J Chem Neuroanat 26: 317-330.
44. Harrison BJ, Pujol J, Lopez-Sola M, Hernandez-Ribas R, Deus J, Ortiz H, Soriano-Mas C, Yücel M, Pantelis C, Cardoner N ( 2008a): Consistency and functional specialization in the default mode brain network. Proc Natl Acad Sci USA 105; 9781-9786.
45. Harrison BJ, Pujol J, Ortiz H, Fornito A, Pantelis C, Yücel M. ( 2008b): Modulation of brain resting-state networks by sad mood induction. PLoS ONE 3: e1794.
46. Harrison BJ, Soriano-Mas C, Pujol J, Ortiz H, Lopez-Sola M, Hernandez-Ribas R, Deus J, Alonso P, Yücel M, Pantelis C, Menchon JM, Cardoner N ( 2009): Altered corticostriatal functional connectivity in obsessive-compulsive disorder. Arch Gen Psychiatry 66: 1189-1200.
47. Harrison BJ, Yücel M, Fornito A, Wood SJ, Seal ML, Clarke K, Pantelis C ( 2007a): Characterizing anterior cingulate activation in chronic schizophrenia: A group and single-subject fMRI study. Acta Psychiatr Scand 116: 271-279.
48. Harrison BJ, Yücel M, Pujol J, Pantelis C ( 2007b): Task-induced deactivation of midline cortical regions in schizophrenia assessed with fMRI. Schizophr Res 91: 82-86.
49. Harrison BJ, Yücel M, Shaw M, Kyrios M, Maruff P, Brewer WJ, Purcell R, Velakoulis D, Strother SC, Scott AM, Nathan PJ, Pantelis C, ( 2006): Evaluating brain activity in obsessive-compulsive disorder: Preliminary insights from a multivariate analysis. Psychiatry Res 147: 227-231.
50. Heckers S, Weiss AP, Deckersbach T, Goff DC, Morecraft RJ, Bush G ( 2004): Anterior cingulate cortex activation during cognitive interference in schizophrenia. Am J Psychiatry 161: 707-715.
51. Lahaye PJ, Poline JB, Flandin G, Dodel S, Garnero L ( 2003): Functional connectivity: studying nonlinear, delayed interactions between BOLD signals. Neuroimage 20: 962-974.
52. Lawrence NS, An SK, Mataix-Cols D, Ruths F, Speckens A, Phillips ML ( 2007): Neural responses to facial expressions of disgust but not fear are modulated by washing symptoms in OCD. Biol Psychiatry 61: 1072-1080.
53. Lawrence NS, Ross TJ, Hoffmann R, Garavan H, Stein EA ( 2003): Multiple neuronal networks mediate sustained attention. J Cogn Neurosci 15: 1028-1038.
54. Lazaro L, Caldu X, Junque C, Bargallo N, Andres S, Morer A, Castro-Fornieles J ( 2008): Cerebral activation in children and adolescents with obsessive-compulsive disorder before and after treatment: A functional MRI study. J Psychiatr Res 42: 1051-1059.
55. Leocani L, Locatelli M, Bellodi L, Fornara C, Henin M, Magnani G, Mennea S, Comi G ( 2001): Abnormal pattern of cortical activation associated with voluntary movement in obsessive-compulsive disorder: An EEG study. Am J Psychiatry 158: 140-142.
56. Li YO, Adali T, Calhoun VD ( 2007): Estimating the number of independent components for functional magnetic resonance imaging data. Hum Brain Mapp 28: 1251-1266.
57. Maltby N, Tolin DF, Worhunsky P, O'Keefe TM, Kiehl KA ( 2005): Dysfunctional action monitoring hyperactivates frontal-striatal circuits in obsessive-compulsive disorder: An event-related fMRI study. Neuroimage 24: 495-503.
58. Mantovani A, Lisanby SH, Pieraccini F, Ulivelli M, Castrogiovanni P, Rossi S ( 2006): Repetitive transcranial magnetic stimulation (rTMS) in the treatment of obsessive-compulsive disorder (OCD) and Tourette's syndrome (TS). Int J Neuropsychopharmacol 9: 95-100.
59. Mataix-Cols D, Wooderson S, Lawrence N, Brammer MJ, Speckens A, Phillips ML ( 2004): Distinct neural correlates of washing, checking, and hoarding symptom dimensions in obsessive-compulsive disorder. Arch Gen Psychiatry 61: 564-576.
60. McGuire PK, Bench CJ, Frith CD, Marks IM, Frackowiak RS, Dolan RJ ( 1994): Functional anatomy of obsessive-compulsive phenomena. Br J Psychiatry 164: 459-468.
61. McKeown MJ, Hansen LK, Sejnowsk TJ ( 2003): Independent component analysis of functional MRI: What is signal and what is noise? Curr Opin Neurobiol 13: 620-629.
62. McKiernan KA, D'Angelo BR, Kaufman JN, Binder JR ( 2006): Interrupting the "stream of consciousness": An fMRI investigation. Neuroimage 29: 1185-1191.
63. McKiernan KA, Kaufman JN, Kucera-Thompson J, Binder JR ( 2003): A parametric manipulation of factors affecting task-induced deactivation in functional neuroimaging. J Cogn Neurosci 15: 394-408.
64. Menzies L, Achard S, Chamberlain SR, Fineberg N, Chen CH, del Campo N, Sahakian BJ, Robbins TW, Bullmore E ( 2007): Neurocognitive endophenotypes of obsessive-compulsive disorder. Brain 130( Part 12): 3223-3236.
65. Menzies L, Chamberlain SR, Laird AR, Thelen SM, Sahakian BJ, Bullmore ET ( 2008): Integrating evidence from neuroimaging and neuropsychological studies of obsessive-compulsive disorder: The orbitofronto-striatal model revisited. Neurosci Biobehav Rev 32: 525-549.
66. Modell JG, Mountz JM, Curtis GC, Greden JF ( 1989): Neurophysiologic dysfunction in basal ganglia/limbic striatal and thalamocortical circuits as a pathogenetic mechanism of obsessive-compulsive disorder. J Neuropsychiatry Clin Neurosci 1: 27-36.
67. Murray CJ, Lopez AD ( 1996): Evidence-based health policy-lessons from the Global Burden of Disease Study. Science 274: 740-743.
68. Nakao T, Nakagawa A, Yoshiura T, Nakatani E, Nabeyama M, Yoshizato C, Kudoh A, Tada K, Yoshioka K, Kawamoto M, et al. ( 2005): Brain activation of patients with obsessive-compulsive disorder during neuropsychological and symptom provocation tasks before and after symptom improvement: A functional magnetic resonance imaging study. Biol Psychiatry 57: 901-910.
69. Phillips ML, Marks IM, Senior C, Lythgoe D, O'Dwyer AM, Meehan O, Williams SC, Brammer MJ, Bullmore ET, McGuire PK ( 2000): A differential neural response in obsessive-compulsive disorder patients with washing compared with checking symptoms to disgust. Psychol Med 30: 1037-1050.
70. Pomarol-Clotet E, Canales-Rodriguez EJ, Salvador R, Sarro S, Gomar JJ, Vila F, Ortiz-Gil J, Iturria-Medina Y, Capdevila A, McKenna PJ ( 2010): Medial prefrontal cortex pathology in schizophrenia as revealed by convergent findings from multimodal imaging. Mol Psychiatry 15: 823-830.
71. Pujol J, Harrison BJ, Ortiz H, Deus J, Soriano-Mas C, Lopez-Sola M, Yücel M, Perich X, Cardoner N ( 2009a): Influence of the fusiform gyrus on amygdala response to emotional faces in the non-clinical range of social anxiety. Psychol Med 39: 1177-1187.
72. Pujol J, Lopez-Sola M, Ortiz H, Vilanova JC, Harrison BJ, Yücel M, Soriano-Mas C, Cardoner N, Deus J ( 2009b): Mapping brain response to pain in fibromyalgia patients using temporal analysis of FMRI. PLoS One 4: e5224.
73. Pujol J, Soriano-Mas C, Alonso P, Cardoner N, Menchon JM, Deus J, Vallejo J ( 2004): Mapping structural brain alterations in obsessive-compulsive disorder. Arch Gen Psychiatry 61: 720-730.
74. Pujol J, Torres L, Deus J, Cardoner N, Pifarre J, Capdevila A, Vallejo J ( 1999): Functional magnetic resonance imaging study of frontal lobe activation during word generation in obsessive-compulsive disorder. Biol Psychiatry 45: 891-897.
75. Raichle ME, MacLeod AM, Snyder AZ, Powers WJ, Gusnard DA, Shulman GL ( 2001): A default mode of brain function. Proc Natl Acad Sci USA 98: 676-682.
76. Rajapakse JC, Tan CL, Zheng X, Mukhopadhyay S, Yang K ( 2006): Exploratory analysis of brain connectivity with ICA. IEEE Eng Med Biol Mag 25: 102-111.
77. Rauch SL, Jenike MA, Alpert NM, Baer L, Breiter HC, Savage CR, Fischman AJ ( 1994): Regional cerebral blood flow measured during symptom provocation in obsessive-compulsive disorder using oxygen 15-labeled carbon dioxide and positron emission tomography. Arch Gen Psychiatry 51: 62-70.
78. Rauch SL, Shin LM, Dougherty DD, Alpert NM, Fischman AJ, Jenike MA ( 2002): Predictors of fluvoxamine response in contamination-related obsessive compulsive disorder: A PET symptom provocation study. Neuropsychopharmacology 27: 782-791.
79. Remijnse PL, Nielen MM, van Balkom AJ, Cath DC, van Oppen P, Uylings HB, Veltman DJ ( 2006): Reduced orbitofrontal-striatal activity on a reversal learning task in obsessive-compulsive disorder. Arch Gen Psychiatry 63: 1225-1236.
80. Roebroeck A, Formisano E, Goebel R ( 2005): Mapping directed influence over the brain using Granger causality and fMRI. Neuroimage 25: 230-242.
81. Rombouts SA, Damoiseaux JS, Goekoop R, Barkhof F, Scheltens P, Smith SM, Beckmann CF ( 2009): Model-free group analysis shows altered BOLD FMRI networks in dementia. Hum Brain Mapp 30: 256-266.
82. Rossi S, Bartalini S, Ulivelli M, Mantovani A, Di Muro A, Goracci A, Castrogiovanni P, Battistini N, Passero S ( 2005): Hypofunctioning of sensory gating mechanisms in patients with obsessive-compulsive disorder. Biol Psychiatry 57: 16-20.
83. Sanavio E ( 1988): Obsessions and compulsions: the Padua Inventory. Behav Res Ther 26: 169-177.
84. Saxena S ( 2003): Neuroimaging and the pathophysiology of obsessive compulsive disorder. Fu C, Senior C, Russell TA, Weinberger DR, Murray R, editors. London: Martin Dunitz. pp 191-224.
85. Schienle A, Schafer A, Stark R, Walter B, Vaitl D ( 2005): Neural responses of OCD patients towards disorder-relevant, generally disgust-inducing and fear-inducing pictures. Int J Psychophysiol 57: 69-77.
86. Seeley WW, Allman JM, Carlin DA, Crawford RK, Macedo MN, Greicius MD, Dearmond SJ, Miller BL. ( 2007a): Divergent social functioning in behavioral variant frontotemporal dementia and Alzheimer disease: reciprocal networks and neuronal evolution. Alzheimer Dis Assoc Disord 21: S50-S57.
87. Seeley WW, Menon V, Schatzberg AF, Keller J, Glover GH, Kenna H, Reiss AL, Greicius MD ( 2007b): Dissociable intrinsic connectivity networks for salience processing and executive control. J Neurosci 27: 2349-2356.
88. Shapira NA, Liu Y, He AG, Bradley MM, Lessig MC, James GA, Stein DJ, Lang PJ, Goodman WK ( 2003): Brain activation by disgust-inducing pictures in obsessive-compulsive disorder. Biol Psychiatry 54: 751-756.
89. Simpson JRJr., Snyder AZ, Gusnard DA, Raichle ME ( 2001): Emotion-induced changes in human medial prefrontal cortex: I. During cognitive task performance. Proc Natl Acad Sci USA 98: 683-687.
90. Smith SM, Fox PT, Miller KL, Glahn DC, Fox PM, Mackay CE, Filippini N, Watkins KE, Toro R, Laird AR, Beckmann CF ( 2009): Correspondence of the brain's functional architecture during activation and rest. Proc Natl Acad Sci USA 116: 13040-13045.
91. Soriano-Mas C, Pujol J, Alonso P, Cardoner N, Menchon JM, Harrison BJ, Deus J, Vallejo J, Gaser C ( 2007): Identifying patients with obsessive-compulsive disorder using whole-brain anatomy. Neuroimage 35: 1028-1037.
92. Sridharan D, Levitin DJ, Menon V ( 2008): A critical role for the right fronto-insular cortex in switching between central-executive and default-mode networks. Proc Natl Acad Sci USA 105: 12569-12574.
93. Stern ER, Welsh RC, Fitzgerald KD, Taylor SF ( 2009): Topographic analysis of individual activation patterns in medial frontal cortex in schizophrenia. Hum Brain Mapp 30: 2146-2156.
94. Tabachnick BG, Fidell LS ( 2001): Using Multivariate Statistics, 4th ed. Needham Heights, MA: Allyn & Bacon.
95. Toro R, Fox PT, Paus T ( 2008): Functional coactivation map of the human brain. Cereb Cortex 18: 2553-2559.
96. Ursu S, Stenger VA, Shear MK, Jones MR, Carter CS ( 2003): Overactive action monitoring in obsessive-compulsive disorder: Evidence from functional magnetic resonance imaging. Psychol Sci 14: 347-353.
97. van den Heuvel OA, Remijnse PL, Mataix-Cols D, Vrenken H, Groenewegen HJ, Uylings HB, van Balkom AJ, Veltman DJ ( 2008): The major symptom dimensions of obsessive-compulsive disorder are mediated by partially distinct neural systems. Brain 132: 853-868.
98. van den Heuvel OA, Veltman DJ, Groenewegen HJ, Dolan RJ, Cath DC, Boellaard R, Mesina CT, van Balkom AJ, van Oppen P, Witter MP, Lammertsma AA, van Dyck R. ( 2004): Amygdala activity in obsessive-compulsive disorder with contamination fear: A study with oxygen-15 water positron emission tomography. Psychiatry Res 132: 225-237.
99. van der Wee NJ, Ramsey NF, Jansma JM, Denys DA, van Megen HJ, Westenberg HM, Kahn RS ( 2003): Spatial working memory deficits in obsessive compulsive disorder are associated with excessive engagement of the medial frontal cortex. Neuroimage 20: 2271-2280.
100. Wechsler D ( 1999): Wechsler Abbreviated Scale of Intelligence Manual. San Antonio: The Psychological Corporation.
101. Weis S, Hausmann M, Stoffers B, Sturm W: Dynamic changes in functional cerebral connectivity of spatial cognition during the menstrual cycle (in press).
102. Weissman DH, Roberts KC, Visscher KM, Woldorff MG ( 2006): The neural bases of momentary lapses in attention. Nat Neurosci 9: 971-978.
103. Whiteside SP, Port JD, Abramowitz JS ( 2004): A meta-analysis of functional neuroimaging in obsessive-compulsive disorder. Psychiatry Res 132: 69-79.
104. Yücel M, Brewer WJ, Harrison BJ, Fornito A, O'Keefe GJ, Olver J, Scott AM, Egan GF, Velakoulis D, McGorry PD, et al. ( 2007a): Anterior cingulate activation in antipsychotic-naive first-episode schizophrenia. Acta Psychiatr Scand 115: 155-158.
105. Yücel M, Harrison BJ, Wood SJ, Fornito A, Wellard RM, Pujol J, Clarke K, Phillips ML, Kyrios M, Velakoulis D, et al. ( 2007b): Functional and biochemical alterations of the medial frontal cortex in obsessive-compulsive disorder. Arch Gen Psychiatry 64: 946-955.
106. Yücel M, Lubman DI, Harrison BJ, Fornito A, Allen NB, Wellard RM, Roffel K, Clarke K, Wood SJ, Forman SD, et al. ( 2007c): A combined spectroscopic and functional MRI investigation of the dorsal anterior cingulate region in opiate addiction. Mol Psychiatry 12: 691-702.