Synthetic scaffold coating with adeno-associated virus encoding BMP2 to promote endogenous bone repair

Cell and Tissue Research

Volumn 347, Issue 3, 2012, Pages 575-588

  Dupont, Kenneth M ^a,b,c   Boerckel, Joel D ^a,c   Stevens, Hazel Y ^a,c   Diab, Tamim ^a,c   Kolambkar, Yash M ^a   Takahata, Masahiko ^d   Schwarz, Edward M ^d   Guldberg, Robert E ^a,c  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^c EXPONENT INC   (United States)

^d UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

Bone morphogenetic protein 2 (BMP2); Human; Large bone defect; Self complementary adeno associated virus (scAAV); Stem cells; Synthetic scaffold

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; PARVOVIRUS VECTOR; POLYCAPROLACTONE; TISSUE SCAFFOLD;

AMNIOTIC FLUID CELL; ARTICLE; BONE DEFECT; BONE DEVELOPMENT; BONE GROWTH; BONE REGENERATION; BONE REMODELING; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVITY; EX VIVO GENE TRANSFER; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO GENE TRANSFER; MATERIAL COATING; MESENCHYMAL STEM CELL; PRIORITY JOURNAL; THERAPY EFFECT; TISSUE ENGINEERING; UPREGULATION; VIRAL GENE DELIVERY SYSTEM;

AMNIOTIC FLUID; ANIMALS; BETA-GALACTOSIDASE; BONE AND BONES; BONE MORPHOGENETIC PROTEIN 2; CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; COATED MATERIALS, BIOCOMPATIBLE; DEPENDOVIRUS; DNA; FEMALE; FEMUR; HUMANS; MESENCHYMAL STEM CELLS; OSTEOGENESIS; POLYESTERS; RATS; RATS, NUDE; TISSUE SCAFFOLDS; TRANSDUCTION, GENETIC; WOUND HEALING;

ADENO-ASSOCIATED VIRUS; RATTUS;

EID: 84859436697     PISSN: 0302766X     EISSN: 14320878     Source Type: Journal    
DOI: 10.1007/s00441-011-1197-3     Document Type: Article

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