Theaflavins extracted from black tea inhibit airway mucous hypersecretion induced by cigarette smoke in rats

Inflammation

Volumn 35, Issue 1, 2012, Pages 271-279

  Wu, Haiqiao ^a,b   Li, Qi ^b   Zhou, Xiangdong ^b   Kolosov, Victor P ^c   Perelman, Juliy M ^c  

^a Chongqing Third People's Hospital   (China)

^b CHONGQING MEDICAL UNIVERSITY   (China)

^c Russian Academy of Medical Sciences   (Russian Federation)

Author keywords

Cigarette smoke; Epidermal growth factor receptor; MUC5AC; Theaflavins

Indexed keywords

CIGARETTE SMOKE; EPIDERMAL GROWTH FACTOR RECEPTOR; MUCIN 5AC; THEAFLAVIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CELL INFILTRATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG DOSE INCREASE; DRUG EFFECT; DRUG MECHANISM; ENZYME INACTIVATION; GOBLET CELL; HISTOLOGY; MALE; MUCUS HYPERSECRETION; MUCUS SECRETION; NONHUMAN; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TEA; TREATMENT DURATION;

ANIMALS; BIFLAVONOIDS; CATECHIN; GALLIC ACID; GOBLET CELLS; LUNG; MALE; MUCIN 5AC; MUCUS; RATS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RESPIRATORY SYSTEM; RNA, MESSENGER; SMOKE; TEA; TOBACCO;

ANIMALIA; CAMELLIA SINENSIS; RATTUS;

EID: 84859436279     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-011-9314-8     Document Type: Article

References (25)

1. Chung, K.F. 2005. Inflammatory mediators in chronic obstructive pulmonary disease. Current Drug Targets. Inflammation and Allergy 4(6): 619-625. (Pubitemid 41722372)
2. Wedzicha, J.A., and G.C. Donaldson. 2003. Exacerbations of chronic obstructive pulmonary disease. Respiratory Care 48(12): 1204-1213.
3. Macnee, W. 2007. Pathogenesis of chronic obstructive pulmonary disease. Clinics in Chest Medicine 28(3): 479-513.
4. Pandey, M., and S. Gupta. 2009. Green tea and prostate cancer: from bench to clinic. Frontiers in Bioscience (Elite Edition) 1: 13-25.
5. Banerjee, S., S. Manna, S. Mukherjee, et al. 2006. Black tea polyphenols restrict benzopyrene-induced mouse lung cancer progression through inhibition of Cox-2 and induction of caspase-3 expression. Asian Pacific Journal of Cancer Prevention 7 (4): 661-666.
6. Lee, H.H., C.T. Ho, and J.K. Lin. 2004. Theaflavin-3,3′-digallate and penta-O-galloyl-beta-D-glucose inhibit rat liver microsomal 5alpha-reductase activity and the expression of androgen receptor in LNCaP prostate cancer cells. Carcinogenesis 25(7): 1109-1118.
7. Banerjee, S., S. Manna, P. Saha, C.K. Panda, and S. Das. 2005. Black tea polyphenols suppress cell proliferation and induce apoptosis during benzo(a)pyrene-induced lung carcinogenesis. European Journal of Cancer Prevention 14(3): 215-221. (Pubitemid 40780444)
8. Mizuno, H., Y.Y. Cho, F. Zhu, et al. 2006. Theaflavin-3,3′- digallate induces epidermal growth factor receptor downregulation. Molecular Carcinogenesis 45(3): 204-212. (Pubitemid 43358153)
9. Vermeer, P.D., R. Harson, L.A. Einwalter, et al. 2003. Interleukin-9 induces goblet cell hyperplasia during repair of human airway epithelia. American Journal of Respiratory Cell and Molecular Biology 28(3): 286-295. (Pubitemid 36238005)
10. Griffin, S., T.P. Carroll, C.M. Greene, et al. 2007. Effect of proinflammatory stimuli on mucin expression and inhibition by secretory leucoprotease inhibitor. Cellular Microbiology 9(3): 670-679. (Pubitemid 46231973)
11. Roqers, D.F. 2005. The role of airway secretions in COPD: pathophysiology, epidemiology and pharmacotherapeutic options. COPD 2(3): 341-353.
12. Haswell, L.E., K. Hewitt, D. Thorne, et al. 2010. Cigarette smoke total particulate matter increases mucous secreting cell numbers in vitro: a potential model of goblet cell hyperplasia. Toxicology In Vitro 24(3): 981.
13. Mossman, B.T., K.M. Lounsbury, and S.P. Redy. 2006. Oxidants and signaling by mitogen-activated protein kinases in lung epithelium. American Journal of Respiratory Cell and Molecular Biology 34(6): 666-669. (Pubitemid 43825330)
14. Vernooy, J.H., J.H. Lindeman, J.A. Jacobs, et al. 2004. Increased activity of matrix metalloproteinase-8 and matrix metalloproteinase-9 in induced sputum from patients with COPD. Chest 126(6): 1802-1810. (Pubitemid 39643983)
15. Rubin, B.K. 2002. Physiology of airway mucus clearance. Respiratory Care 47(7): 761-768.
16. Foster, W.M. 2002. Mucociliary transport and cough in humans. Pulmonary Pharmacology and Therapeutics 15(3): 277-282.
17. Voynow, J.A., S.J. Gendler, and M.C. Rose. 2006. Regulation of mucin genes in chronic inflammatory airway diseases. American Journal of Respiratory Cell and Molecular Biology 34(6): 661-665. (Pubitemid 43825329)
18. Kettle, R., J. Simmons, F. Sehindler, et al. 2010. Regulation of neuregulin 1beta1-induced MUC5AC and MUC5B expression in human airway epithelium. American Journal of Respiratory Cell and Molecular Biology 42(4): 472-481.
19. Wine, J.J., and N.S. Joo. 2004. Submucosal glands and airway defense. Proceedings of the American Thoracic Society 1(1): 47-53.
20. Shao, M.X., T. Nakanaga, and J.A. Nadel. 2004. Cigarette smoke induces MUC5AC mucin overproduction via tumor necrosis factor-alpha-converting enzyme in human airway epithelial (NCI-H292) cells. American Journal of Physiology. Lung Cellular and Molecular Physiology 287(2): L420-L427. (Pubitemid 38943925)
21. Takeyama, K., K. Dabbagh, Jeong, et al. 2000. Oxidative stress causes mucin synthesis via transactivation of epidermal growth factor receptor: role of neutrophils. Journal of Immunology 164: 1546-1552. (Pubitemid 30067272)
22. Lee, H.M., L. Malm, K. Dabbagh, et al. 2001. Epidermal growth factor receptor signaling mediates regranulation of rat nasal goblet cells. The Journal of Allergy and Clinical Immunology 107: 1046-1050. (Pubitemid 32523346)
23. Shim, J.J., K. Dabbagh, I.F. Ueki, et al. 2001. IL-13 induces mucin production by stimulating epidermal growth factor receptors and by activating neutrophils. The American Journal of Physiology 280: L134-L140.
24. Perrais, M., P. Pigny, M.C. Copin, et al. 2002. Induction of MUC2 and MUC5AC mucins by factors of the epidermal growth factor (EGF) family is mediated by EGF receptor/Ras/Raf/extracellular signal-regulated kinase cascade and Sp1. Biological Chemistry 277 (35): 32258-32267. (Pubitemid 34969042)
25. Kitazaki, T., H. Soda, S. Doi, et al. 2005. Gefitinib inhibits MUC5AC synthesis in mucin-secreting non-small cell lung cancer cells. Lung Cancer 50: 19-24. (Pubitemid 41297465)