Prevalidation study of the Syrian hamster embryo (SHE) cell transformation assay at pH 6.7 for assessment of carcinogenic potential of chemicals

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 744, Issue 1, 2012, Pages 54-63

  Pant, Kamala ^a   Bruce, Shannon W ^a   Sly, Jamie E ^a   Kunkelmann, Thorsten ^b   Kunz Bohnenberger, Susanne ^b   Poth, Albrecht ^b   Engelhardt, Günter ^c   Schulz, Markus ^c   Schwind, Karl Rainer ^c  

^a BioReliance   (United States)

^b Harlan   (Switzerland)

^c BASF SE   (Germany)

Author keywords

Cell transformation assay; Morphological transformation; PH 6.7; SHE; Syrian hamster embryo; Validation

Indexed keywords

2 TOLUIDINE; 2,4 DIAMINOTOLUENE; 3 METHYLCHOLANTHRENE; ANTHRACENE; BENZO[A]PYRENE; CARCINOGEN; PHTHALIC ANHYDRIDE; UNCLASSIFIED DRUG; TOLUIDINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOASSAY; CARCINOGEN TESTING; CARCINOGENICITY; CELL ASSAY; CELL PH; CELL TRANSFORMATION; CELL TRANSFORMATION ASSAY; CLINICAL PROTOCOL; CONTROLLED STUDY; EMBRYO; EMBRYO CELL; LABORATORY TEST; NONHUMAN; PRIORITY JOURNAL; REPRODUCIBILITY; STANDARDIZATION; SYRIAN HAMSTER; VALIDATION STUDY; CHEMICAL CARCINOGENESIS; RODENT;

ANIMALS; CARCINOGENICITY TESTS; CARCINOGENS; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; CRICETINAE; HYDROGEN-ION CONCENTRATION; MESOCRICETUS; REPRODUCIBILITY OF RESULTS; RESEARCH DESIGN; PREDICTIVE VALUE OF TESTS;

ANIMALIA; MESOCRICETUS AURATUS; RODENTIA;

EID: 84859432348     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2011.12.005     Document Type: Article

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