Genistein inhibit cytokines or growth factor-induced proliferation and transformation phenotype in fibroblast-like synoviocytes of rheumatoid arthritis

Inflammation

Volumn 35, Issue 1, 2012, Pages 377-387

  Zhang, Yujun ^a   Dong, Jianqiang ^a   He, Peiying ^a   Li, Wende ^a   Zhang, Qi ^a   Li, Na ^a   Sun, Tiezheng ^a  

^a PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

Author keywords

Fibroblast like synoviocyte; Genistein; Rheumatoid arthritis; Transformation

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; EPIDERMAL GROWTH FACTOR; GELATINASE A; GELATINASE B; GENISTEIN; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; TUMOR NECROSIS FACTOR ALPHA;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CELL ASSAY; CELL COUNT; CELL GROWTH; CELL PROLIFERATION; CELL TRANSFORMATION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; FIBROBLAST CULTURE; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; GROWTH INHIBITION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS INHIBITION; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SYNOVIOCYTE; UPREGULATION;

ANTHRACENES; ARTHRITIS, RHEUMATOID; CELL CYCLE; CELL PROLIFERATION; CELLS, CULTURED; EPIDERMAL GROWTH FACTOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; G1 PHASE CELL CYCLE CHECKPOINTS; GENISTEIN; HUMANS; INTERLEUKIN-1BETA; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; SYNOVIAL MEMBRANE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84859426925     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-011-9365-x     Document Type: Article

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