Blockade of I Ca suppresses early afterdepolarizations and reduces transmural dispersion of repolarization in a whole heart model of chronic heart failure

British Journal of Pharmacology

Volumn 166, Issue 2, 2012, Pages 557-568

  Milberg, P ^a   Fink, M ^b   Pott, C ^a   Frommeyer, G ^a   Biertz, J ^a   Osada, N ^c   Stypmann, J ^a,c   Monnig G ^a   Koopmann, M ^a   Breithardt, G ^a   Eckardt, L ^a  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

heart failure; I Ca L block; myocardial repolarization; ventricular tachyarrhythmias

Indexed keywords

CALCIUM CHANNEL; POTASSIUM ION; VERAPAMIL;

AFTERDEPOLARIZATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIARRHYTHMIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; ENDOCARDIUM; FEMALE; HEART DEPOLARIZATION; HEART FAILURE; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; HEART REPOLARIZATION; ISOLATED HEART; MATHEMATICAL MODEL; NONHUMAN; POLYMORPHIC VENTRICULAR TACHYCARDIA; PRIORITY JOURNAL; RABBIT;

ACTION POTENTIALS; ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; ERYTHROMYCIN; FEMALE; HEART; HEART FAILURE; MODELS, BIOLOGICAL; MYOCYTES, CARDIAC; POTASSIUM CHANNEL BLOCKERS; RABBITS; TACHYCARDIA, VENTRICULAR; VERAPAMIL;

EID: 84859425720     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01721.x     Document Type: Article

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