The effect of acute aromatase inhibition on breast parenchymal enhancement in magnetic resonance imaging: A prospective pilot clinical trial

Menopause

Volumn 19, Issue 4, 2012, Pages 420-425

  Mousa, Noha A ^a,b   Eiada, Riham ^a,c   Crystal, Pavel ^a,c   Nayot, Dan ^a   Casper, Robert F ^a,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b ASSIUT UNIVERSITY   (Egypt)

^c MOUNT SINAI HOSPITAL   (Canada)

Author keywords

Aromatase inhibitors; Breast; Enhancement; Magnetic resonance imaging; Menopause

Indexed keywords

AROMATASE INHIBITOR; ESTROGEN; GADOBUTROL; GADODIAMIDE; GADOVISTA; LETROZOLE; UNCLASSIFIED DRUG;

ADULT; AGED; ARTHRALGIA; ARTICLE; BREAST CANCER; BREAST EXAMINATION; CLINICAL ARTICLE; CONTRAST ENHANCEMENT; DRUG MEGADOSE; FEMALE; HEADACHE; HUMAN; IMAGE ENHANCEMENT; IMAGE QUALITY; NUCLEAR MAGNETIC RESONANCE IMAGING; PARENCHYMA; PHASE 2 CLINICAL TRIAL; PILOT STUDY; POSTMENOPAUSE; PROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY;

ADULT; AROMATASE INHIBITORS; BREAST; BREAST NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; IMAGE ENHANCEMENT; MAGNETIC RESONANCE IMAGING; MIDDLE AGED; PILOT PROJECTS; POSTMENOPAUSE; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; REFERENCE VALUES;

EID: 84859425042     PISSN: 10723714     EISSN: 15300374     Source Type: Journal    
DOI: 10.1097/gme.0b013e31823772a8     Document Type: Article

References (39)

1. Crowe JP, Patrick RJ, Rim A. The importance of preoperative breast MRI for patients newly diagnosed with breast cancer. Breast J 2009; 15:52-60.
2. Sardanelli F, Giuseppetti GM, Panizza P, et al. Sensitivity of MRI versus mammography for detecting foci of multifocal, multicentric breast cancer in Fatty and dense breasts using the whole-breast pathologic examination as a gold standard. AJR Am J Roentgenol 2004;183:1149-1157. (Pubitemid 44185114)
3. Bedrosian I, Mick R, Orel SG, et al. Changes in the surgical management of patients with breast carcinoma based on preoperative magnetic resonance imaging. Cancer 2003;98:468-473. (Pubitemid 36885985)
4. Hagen AI, Kvistad KA, Maehle L, et al. Sensitivity of MRI versus conventional screening in the diagnosis of BRCA-associated breast cancer in a national prospective series. Breast 2007;16:367-374. (Pubitemid 47157808)
5. Leach MO. Breast cancer screening in women at high risk using MRI. NMR Biomed 2009;22:17-27.
6. Komenaka IK, Ditkoff BA, Joseph KA, et al. The development of interval breast malignancies in patients with BRCA mutations. Cancer 2004;100:2079-2083. (Pubitemid 38580324)
7. Saslow D, Boetes C, Burke W, et al. American Cancer Society guidelines for breast screening with MRI as an adjunct to mammography. CA Cancer J Clin 2007;57:75-89. (Pubitemid 46535708)
8. Piccoli CW. Contrast-enhanced breast MRI: factors affecting sensitivity and specificity. Eur Radiol 1997;7:281-288.
9. Teifke A, Hlawatsch A, Beier T, et al. Undetected malignancies of the breast: dynamic contrast-enhanced MR imaging at 1.0 T. Radiology 2002;224:881-888. (Pubitemid 34919827)
10. Peters NH, Borel Rinkes IH, Zuithoff NP, Mali WP, Moons KG, Peeters PH. Meta-analysis of MR imaging in the diagnosis of breast lesions. Radiology 2008;246:116-124. (Pubitemid 350305034)
11. Bluemke DA, Gatsonis CA, Chen MH, et al. Magnetic resonance imaging of the breast prior to biopsy. JAMA 2004;292:2735-2742. (Pubitemid 39628252)
12. Sariguney Y, Demirtas Y, Findikcioglu F, et al. Proper timing of breast reduction during the menstrual cycle. Ann Plast Surg 2004;53:528-531. (Pubitemid 39565022)
13. Longacre TA, Bartow SA. A correlative morphologic study of human breast and endometriumin themenstrual cycle. Am J Surg Pathol 1986;10:382-393. (Pubitemid 16066440)
14. Kuhl CK, Mielcareck P, Klaschik S, et al. Dynamic breast MR imaging: are signal intensity time course data useful for differential diagnosis of enhancing lesions? Radiology 1999;211:101-110. (Pubitemid 29161739)
15. Vogel PM, Georgiade NG, Fetter BF. The correlation of histologic changes in the human breast with the menstrual cycle. Am J Pathol 1981;104:23-34. (Pubitemid 11033901)
16. Crandall CJ, Aragaki AK, Chlebowski RT, et al. New-onset breast tenderness after initiation of estrogen plus progestin therapy and breast cancer risk. Arch Intern Med 2009;169:1684-1691.
17. Delille JP, Slanetz PJ, Yeh ED, Kopans DB, Garrido L. Physiologic changes in breast magnetic resonance imaging during the menstrual cycle: Perfusion imaging, signal enhancement, and influence of the T1 relaxation time of breast tissue. Breast J 2005;11:236-241. (Pubitemid 41026036)
18. Partridge SC, McKinnon GC, Henry RG, Hylton NM. Menstrual cycle variation of apparent diffusion coefficients measured in the normal breast using MRI. J Magn Reson Imaging 2001;14:433-438. (Pubitemid 32906561)
19. Fowler PA, Casey CE, Cameron GG, Foster MA, Knight CH. Cyclic changes in composition and volume of the breast during the menstrual cycle, measured by magnetic resonance imaging. Br J Obstet Gynaecol 1990;97:595-602. (Pubitemid 20220764)
20. Ellis RL. Optimal timing of breast MRI examinations for premenopausal women who do not have a normal menstrual cycle. Am J Roentgenol 2009;193:1738-1740.
21. Dzendrowskyj TE, Noyszewski EA, Beers J, Bolinger L. Lipid composition changes in normal breast throughout the menstrual cycle. MAGMA 1997;5:105-110. (Pubitemid 27328553)
22. Sharma U, Kumar M, Sah RG, Jagannathan NR. Study of normal breast tissue by in vivo volume localized proton MR spectroscopy: variation of water-fat ratio in relation to the heterogeneity of the breast and the menstrual cycle. Magn Reson Imaging 2009;27:785-791.
23. Hussain Z, Roberts N, Whitehouse GH, Garcia-Finana M, Percy D. Estimation of breast volume and its variation during the menstrual cycle using MRI and stereology. Br J Radiol 1999;72:236-245. (Pubitemid 29154669)
24. Morrow M, Chatterton RT Jr, Rademaker AW, et al. A prospective study of variability in mammographic density during the menstrual cycle. Breast Cancer Res Treat 2010;121:565-574.
25. Lasco A, Gaudio A, Morini E, et al. Effect of long-term treatment with raloxifene on mammary density in postmenopausal women. Menopause 2006;13:787-792. (Pubitemid 44435033)
26. Eilertsen AL, Karssemeijer N, Skaane P, Qvigstad E, Sandset PM. Differential impact of conventional and low-dose oral hormone therapy, tibolone and raloxifene on mammographic breast density, assessed by an automated quantitative method. BJOG 2008;115:773-779. (Pubitemid 351514578)
27. Mousa NA, Crystal P, Wolfman WL, Bedaiwy MA, Casper RF. Aromatase inhibitors and mammographic breast density in postmenopausal women receiving hormone therapy. Menopause 2008;15:875-884.
28. Cigler T, Tu D, Yaffe MJ, et al. A randomized, placebo-controlled trial (NCIC CTG MAP1) examining the effects of letrozole on mammographic breast density and other end organs in postmenopausal women. Breast Cancer Res Treat 2010;120:427-435.
29. Oksa S, Parkkola R, Luukkaala T, Mäenpää J. Breast magnetic resonance imaging findings in women treated with toremifene for premenstrual mastalgia. Acta Radiol 2009;50:984-989.
30. Eng-Wong J, Orzano-Birgani J, Chow CK, et al. Effect of raloxifene on mammographic density and breast magnetic resonance imaging in premenopausal women at increased risk for breast cancer. Cancer Epidemiol Biomarkers Prev 2008;17:1696-1701.
31. Schnall MD, Orel SG, McDermott J, Englander SA. Breast MRI on patients taking tamoxifen. Proc Intl Soc Magn Reson Med 1999;7:360.
32. Lonning P. Overview of aromatase inhibitors and inactivators in the treatment of advanced breast cancer. In: Miller WR, ed. Endocrine Therapy in Breast Cancer. Basel, Swizterland: Marcel Dekker; 2002:33-46.
33. Tekmal RR, Ramachandra N, Gubba S, et al. Overexpression of int-5/aromatase in mammary glands of transgenic mice results in the induction of hyperplasia and nuclear abnormalities. Cancer Res 1996;56:3180-3185. (Pubitemid 26242957)
34. Pasqualini JR, Chetrite GS. Estradiol as an anti-aromatase agent in human breast cancer cells. J Steroid Biochem Mol Biol 2006;98:12-17. (Pubitemid 43113239)
35. Cleland WH, Mendelson CR, Simpson ER. Effects of aging and obesity on aromatase activity of human adipose cells. J Clin Endocrinol Metab 1985;60:174-177. (Pubitemid 15194667)
36. Honma N, Takubo K, Sawabe M, et al. Estrogen-metabolizing enzymes in breast cancers from women over the age of 80 years. J Clin Endocrinol Metab 2006;91:607-613. (Pubitemid 43236932)
37. Misso ML, Jang C, Adams J, et al. Adipose aromatase gene expression is greater in older women and is unaffected by postmenopausal estrogen therapy. Menopause 2005;12:210-215. (Pubitemid 40464290)
38. Walker RA, Martin CV. The aged breast. J Pathol 2007;211:232-240. (Pubitemid 46195521)
39. Morakkabati N, Leutner CC, Schmiedel A, Schild HH, Kuhl CK. Breast MR imaging during or soon after radiation therapy. Radiology 2003; 229:893-901. (Pubitemid 37467598)