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Volumn 27, Issue SUPPL.3, 2012, Pages 3-7

Therapeutic options for refractory gastroesophageal reflux disease

Author keywords

Gastroesophageal reflux disease (GERD); Heartburn; Proton pump inhibitors (PPIs); Refractory GERD

Indexed keywords

ADX 10059; ANALGESIC AGENT; ARBACLOFEN PLACARBIL; BACLOFEN; BOTULINUM TOXIN; COLESTYRAMINE; HISTAMINE H2 RECEPTOR ANTAGONIST; PROTON PUMP INHIBITOR; SEROTONIN UPTAKE INHIBITOR; TRAZODONE; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG;

EID: 84859407553     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2012.07064.x     Document Type: Review
Times cited : (48)

References (53)
  • 1
    • 0030931230 scopus 로고    scopus 로고
    • Prevalence and clinical spectrum of gastroesophageal reflux: a population-based study in Olmsted County, Minnesota
    • Locke GR 3rd, Talley NJ, Fett SL, Zinsmeister AR, Melton LJ 3rd. Prevalence and clinical spectrum of gastroesophageal reflux: a population-based study in Olmsted County, Minnesota. Gastroenterology 1997; 112: 1448-56.
    • (1997) Gastroenterology , vol.112 , pp. 1448-1456
    • Locke III, G.R.1    Talley, N.J.2    Fett, S.L.3    Zinsmeister, A.R.4    Melton III, L.J.5
  • 2
    • 0017202313 scopus 로고
    • Symptomatic gastroesophageal reflux: incidence and precipitating factors
    • Nebel OT, Fornes MF, Castell DO. Symptomatic gastroesophageal reflux: incidence and precipitating factors. Am. J. Dig. Dis. 1976; 21: 953-6.
    • (1976) Am. J. Dig. Dis. , vol.21 , pp. 953-956
    • Nebel, O.T.1    Fornes, M.F.2    Castell, D.O.3
  • 3
    • 0030962574 scopus 로고    scopus 로고
    • Speed of healing and symptom relief in grade II to IV gastroesophageal reflux disease: a meta-analysis
    • Chiba N, De Gara CJ, Wilkinson JM, Hunt RH. Speed of healing and symptom relief in grade II to IV gastroesophageal reflux disease: a meta-analysis. Gastroenterology 1997; 112: 1798-810.
    • (1997) Gastroenterology , vol.112 , pp. 1798-1810
    • Chiba, N.1    De Gara, C.J.2    Wilkinson, J.M.3    Hunt, R.H.4
  • 5
    • 77954136996 scopus 로고    scopus 로고
    • Management of gastroesophageal reflux disease that does not respond well to proton pump inhibitors
    • Hershcovici T, Fass R. Management of gastroesophageal reflux disease that does not respond well to proton pump inhibitors. Curr. Opin. Gastroenterol. 2010; 26: 367-78.
    • (2010) Curr. Opin. Gastroenterol. , vol.26 , pp. 367-378
    • Hershcovici, T.1    Fass, R.2
  • 6
  • 7
    • 61949154981 scopus 로고    scopus 로고
    • Proton pump inhibitor failure-what are the therapeutic options?
    • Fass R. Proton pump inhibitor failure-what are the therapeutic options? Am. J. Gastroenterol. 2009; 104 (Suppl. 2): S33-8.
    • (2009) Am. J. Gastroenterol. , vol.104 , Issue.2 SUPPL.
    • Fass, R.1
  • 8
    • 58849095408 scopus 로고    scopus 로고
    • Management of heartburn not responding to proton pump inhibitors
    • Fass R, Sifrim D. Management of heartburn not responding to proton pump inhibitors. Gut 2009; 58: 295-309.
    • (2009) Gut , vol.58 , pp. 295-309
    • Fass, R.1    Sifrim, D.2
  • 10
    • 41149098654 scopus 로고    scopus 로고
    • Persistent heartburn in a patient on proton-pump inhibitor
    • Fass R. Persistent heartburn in a patient on proton-pump inhibitor. Clin. Gastroenterol. Hepatol. 2008; 6: 393-400.
    • (2008) Clin. Gastroenterol. Hepatol. , vol.6 , pp. 393-400
    • Fass, R.1
  • 11
    • 33646392726 scopus 로고    scopus 로고
    • Are lifestyle measures effective in patients with gastroesophageal reflux disease? An evidence-based approach
    • Kaltenbach T, Crockett S, Gerson LB. Are lifestyle measures effective in patients with gastroesophageal reflux disease? An evidence-based approach. Arch. Intern. Med. 2006; 166: 965-71.
    • (2006) Arch. Intern. Med. , vol.166 , pp. 965-971
    • Kaltenbach, T.1    Crockett, S.2    Gerson, L.B.3
  • 12
    • 78049482362 scopus 로고    scopus 로고
    • Sensitization to foods in gastroesophageal reflux disease and its relation to eosinophils in the esophagus: is it of clinical importance?
    • Pomiecinski F, Yang AC, Navarro-Rodrigues T, Kalil J, Castro FF. Sensitization to foods in gastroesophageal reflux disease and its relation to eosinophils in the esophagus: is it of clinical importance? Ann. Allergy Asthma Immunol. 2010; 105: 359-63.
    • (2010) Ann. Allergy Asthma Immunol. , vol.105 , pp. 359-363
    • Pomiecinski, F.1    Yang, A.C.2    Navarro-Rodrigues, T.3    Kalil, J.4    Castro, F.F.5
  • 13
    • 0031787618 scopus 로고    scopus 로고
    • Ranitidine controls nocturnal gastric acid breakthrough on omeprazole: a controlled study in normal subjects
    • Peghini PL, Katz PO, Castell DO. Ranitidine controls nocturnal gastric acid breakthrough on omeprazole: a controlled study in normal subjects. Gastroenterology 1998; 115: 1335-9.
    • (1998) Gastroenterology , vol.115 , pp. 1335-1339
    • Peghini, P.L.1    Katz, P.O.2    Castell, D.O.3
  • 14
    • 0036183295 scopus 로고    scopus 로고
    • Long-term effect of H2RA therapy on nocturnal gastric acid breakthrough
    • Fackler WK, Ours TM, Vaezi MF, Richter JE. Long-term effect of H2RA therapy on nocturnal gastric acid breakthrough. Gastroenterology 2002; 122: 625-32.
    • (2002) Gastroenterology , vol.122 , pp. 625-632
    • Fackler, W.K.1    Ours, T.M.2    Vaezi, M.F.3    Richter, J.E.4
  • 15
    • 54749123309 scopus 로고    scopus 로고
    • Addition of a H2 receptor antagonist to PPI improves acid control and decreases nocturnal acid breakthrough
    • Mainie I, Tutuian R, Castell DO. Addition of a H2 receptor antagonist to PPI improves acid control and decreases nocturnal acid breakthrough. J. Clin. Gastroenterol. 2008; 42: 676-9.
    • (2008) J. Clin. Gastroenterol. , vol.42 , pp. 676-679
    • Mainie, I.1    Tutuian, R.2    Castell, D.O.3
  • 16
    • 33644831521 scopus 로고    scopus 로고
    • Histamine-2 receptor antagonists at night improve gastroesophageal reflux disease symptoms for patients on proton pump inhibitor therapy
    • Rackoff A, Agrawal A, Hila A, Mainie I, Tutuian R, Castell DO. Histamine-2 receptor antagonists at night improve gastroesophageal reflux disease symptoms for patients on proton pump inhibitor therapy. Dis. Esophagus 2005; 18: 370-3.
    • (2005) Dis. Esophagus , vol.18 , pp. 370-373
    • Rackoff, A.1    Agrawal, A.2    Hila, A.3    Mainie, I.4    Tutuian, R.5    Castell, D.O.6
  • 17
    • 53049088882 scopus 로고    scopus 로고
    • American Gastroenterological Association Medical Position Statement on the management of gastroesophageal reflux disease
    • 91 e1-5.
    • Kahrilas PJ, Shaheen NJ, Vaezi MF etal. American Gastroenterological Association Medical Position Statement on the management of gastroesophageal reflux disease. Gastroenterology 2008; 135: 1383-91, 91 e1-5.
    • (2008) Gastroenterology , vol.135 , pp. 1383-1391
    • Kahrilas, P.J.1    Shaheen, N.J.2    Vaezi, M.F.3
  • 18
    • 31144435900 scopus 로고    scopus 로고
    • Treatment of patients with persistent heartburn symptoms: a double-blind, randomized trial
    • Fass R, Sontag SJ, Traxler B, Sostek M. Treatment of patients with persistent heartburn symptoms: a double-blind, randomized trial. Clin. Gastroenterol. Hepatol. 2006; 4: 40-56.
    • (2006) Clin. Gastroenterol. Hepatol. , vol.4 , pp. 40-56
    • Fass, R.1    Sontag, S.J.2    Traxler, B.3    Sostek, M.4
  • 19
    • 78149282655 scopus 로고    scopus 로고
    • The gain in quality-adjusted life months by switching to esomeprazole in those with continued reflux symptoms in primary care: encomPASS-a cluster-randomized trial
    • Moayyedi P, Armstrong D, Hunt RH, Lei Y, Bukoski M, White RJ. The gain in quality-adjusted life months by switching to esomeprazole in those with continued reflux symptoms in primary care: encomPASS-a cluster-randomized trial. Am. J. Gastroenterol. 2010; 105: 2341-6.
    • (2010) Am. J. Gastroenterol. , vol.105 , pp. 2341-2346
    • Moayyedi, P.1    Armstrong, D.2    Hunt, R.H.3    Lei, Y.4    Bukoski, M.5    White, R.J.6
  • 20
    • 0031700062 scopus 로고    scopus 로고
    • Nocturnal gastric acidity and acid breakthrough on different regimens of omeprazole 40mg daily
    • Hatlebakk J, Katz P, Kuo B, Castell DO. Nocturnal gastric acidity and acid breakthrough on different regimens of omeprazole 40mg daily. Aliment. Pharmacol. Ther. 1998; 12: 1235-40.
    • (1998) Aliment. Pharmacol. Ther. , vol.12 , pp. 1235-1240
    • Hatlebakk, J.1    Katz, P.2    Kuo, B.3    Castell, D.O.4
  • 21
    • 33947721974 scopus 로고    scopus 로고
    • Efficacy in intra-oesophageal acid suppression may decrease after 2-year continuous treatment with proton pump inhibitors
    • Frazzoni M, Manno M, De Micheli E, Savarino V. Efficacy in intra-oesophageal acid suppression may decrease after 2-year continuous treatment with proton pump inhibitors. Dig. Liver Dis. 2007; 39: 415-21.
    • (2007) Dig. Liver Dis. , vol.39 , pp. 415-421
    • Frazzoni, M.1    Manno, M.2    De Micheli, E.3    Savarino, V.4
  • 22
    • 33748921737 scopus 로고    scopus 로고
    • Acid-suppressive effects of rabeprazole: comparing 10mg and 20mg twice daily in Japanese Helicobacter pylori-negative and -positive CYP2C19 extensive metabolisers
    • Shimatani T, Moriwaki M, Xu J, Tazuma S, Inoue M. Acid-suppressive effects of rabeprazole: comparing 10mg and 20mg twice daily in Japanese Helicobacter pylori-negative and -positive CYP2C19 extensive metabolisers. Dig. Liver Dis. 2006; 38: 802-8.
    • (2006) Dig. Liver Dis. , vol.38 , pp. 802-808
    • Shimatani, T.1    Moriwaki, M.2    Xu, J.3    Tazuma, S.4    Inoue, M.5
  • 23
    • 61849139946 scopus 로고    scopus 로고
    • Clinical trials: healing of erosive oesophagitis with dexlansoprazole MR, a proton pump inhibitor with a novel dual delayed-release formulation-results from two randomized controlled studies
    • Sharma P, Shaheen NJ, Perez MC etal. Clinical trials: healing of erosive oesophagitis with dexlansoprazole MR, a proton pump inhibitor with a novel dual delayed-release formulation-results from two randomized controlled studies. Aliment. Pharmacol. Ther. 2009; 29: 731-41.
    • (2009) Aliment. Pharmacol. Ther. , vol.29 , pp. 731-741
    • Sharma, P.1    Shaheen, N.J.2    Perez, M.C.3
  • 24
    • 70349386118 scopus 로고    scopus 로고
    • Clinical trial: the effects of the proton pump inhibitor dexlansoprazole MR on daytime and nighttime heartburn in patients with non-erosive reflux disease
    • Fass R, Chey WD, Zakko SF etal. Clinical trial: the effects of the proton pump inhibitor dexlansoprazole MR on daytime and nighttime heartburn in patients with non-erosive reflux disease. Aliment. Pharmacol. Ther. 2009; 29: 1261-72.
    • (2009) Aliment. Pharmacol. Ther. , vol.29 , pp. 1261-1272
    • Fass, R.1    Chey, W.D.2    Zakko, S.F.3
  • 25
    • 0034880437 scopus 로고    scopus 로고
    • Receptors and transmission in the brain-gut axis: potential for novel therapies. IV. GABA(B) receptors in the brain-gastroesophageal axis
    • Blackshaw LA. Receptors and transmission in the brain-gut axis: potential for novel therapies. IV. GABA(B) receptors in the brain-gastroesophageal axis. Am. J. Physiol. Heart Circ. Physiol. 2001; 281: G311-15.
    • (2001) Am. J. Physiol. Heart Circ. Physiol. , vol.281
    • Blackshaw, L.A.1
  • 26
    • 24144487047 scopus 로고    scopus 로고
    • Inhibition of transient lower esophageal sphincter relaxation and gastroesophageal reflux by metabotropic glutamate receptor ligands
    • Frisby CL, Mattsson JP, Jensen JM, Lehmann A, Dent J, Blackshaw LA. Inhibition of transient lower esophageal sphincter relaxation and gastroesophageal reflux by metabotropic glutamate receptor ligands. Gastroenterology 2005; 129: 995-1004.
    • (2005) Gastroenterology , vol.129 , pp. 995-1004
    • Frisby, C.L.1    Mattsson, J.P.2    Jensen, J.M.3    Lehmann, A.4    Dent, J.5    Blackshaw, L.A.6
  • 27
    • 0036136088 scopus 로고    scopus 로고
    • Control of transient lower oesophageal sphincter relaxations and reflux by the GABA(B) agonist baclofen in patients with gastro-oesophageal reflux disease
    • Zhang Q, Lehmann A, Ridga R, Dent J, Holloway RH. Control of transient lower oesophageal sphincter relaxations and reflux by the GABA(B) agonist baclofen in patients with gastro-oesophageal reflux disease. Gut 2002; 50: 19-24.
    • (2002) Gut , vol.50 , pp. 19-24
    • Zhang, Q.1    Lehmann, A.2    Ridga, R.3    Dent, J.4    Holloway, R.H.5
  • 28
    • 0033958395 scopus 로고    scopus 로고
    • Control of transient lower esophageal sphincter relaxations and reflux by the GABA(B) agonist baclofen in normal subjects
    • Lidums I, Lehmann A, Checklin H, Dent J, Holloway RH. Control of transient lower esophageal sphincter relaxations and reflux by the GABA(B) agonist baclofen in normal subjects. Gastroenterology 2000; 118: 7-13.
    • (2000) Gastroenterology , vol.118 , pp. 7-13
    • Lidums, I.1    Lehmann, A.2    Checklin, H.3    Dent, J.4    Holloway, R.H.5
  • 29
    • 33748977207 scopus 로고    scopus 로고
    • Effect of baclofen on esophagogastric motility and gastroesophageal reflux in children with gastroesophageal reflux disease: a randomized controlled trial
    • Omari TI, Benninga MA, Sansom L, Butler RN, Dent J, Davidson GP. Effect of baclofen on esophagogastric motility and gastroesophageal reflux in children with gastroesophageal reflux disease: a randomized controlled trial. J. Pediatr. 2006; 149: 436-8.
    • (2006) J. Pediatr. , vol.149 , pp. 436-438
    • Omari, T.I.1    Benninga, M.A.2    Sansom, L.3    Butler, R.N.4    Dent, J.5    Davidson, G.P.6
  • 30
    • 0347708695 scopus 로고    scopus 로고
    • Baclofen decreases acid and non-acid post-prandial gastro-oesophageal reflux measured by combined multichannel intraluminal impedance and pH
    • Vela MF, Tutuian R, Katz PO, Castell DO. Baclofen decreases acid and non-acid post-prandial gastro-oesophageal reflux measured by combined multichannel intraluminal impedance and pH. Aliment. Pharmacol. Ther. 2003; 17: 243-51.
    • (2003) Aliment. Pharmacol. Ther. , vol.17 , pp. 243-251
    • Vela, M.F.1    Tutuian, R.2    Katz, P.O.3    Castell, D.O.4
  • 31
    • 0141757445 scopus 로고    scopus 로고
    • Effect of the GABA(B) agonist baclofen in patients with symptoms and duodeno-gastro-oesophageal reflux refractory to proton pump inhibitors
    • Koek GH, Sifrim D, Lerut T, Janssens J, Tack J. Effect of the GABA(B) agonist baclofen in patients with symptoms and duodeno-gastro-oesophageal reflux refractory to proton pump inhibitors. Gut 2003; 52: 1397-402.
    • (2003) Gut , vol.52 , pp. 1397-1402
    • Koek, G.H.1    Sifrim, D.2    Lerut, T.3    Janssens, J.4    Tack, J.5
  • 32
    • 79954588926 scopus 로고    scopus 로고
    • The analgesic effects of the GABA(B) receptor agonist, baclofen, in a rodent model of functional dyspepsia
    • Liu LS, Shenoy M, Pasricha PJ. The analgesic effects of the GABA(B) receptor agonist, baclofen, in a rodent model of functional dyspepsia. Neurogastroenterol. Motil. 2011; 23: 356-61.
    • (2011) Neurogastroenterol. Motil. , vol.23 , pp. 356-361
    • Liu, L.S.1    Shenoy, M.2    Pasricha, P.J.3
  • 33
    • 70349128208 scopus 로고    scopus 로고
    • Arbaclofen placarbil, a novel R-baclofen prodrug: improved absorption, distribution, metabolism, and elimination properties compared with R-baclofen
    • Lal R, Sukbuntherng J, Tai EH etal. Arbaclofen placarbil, a novel R-baclofen prodrug: improved absorption, distribution, metabolism, and elimination properties compared with R-baclofen. J. Pharmacol. Exp. Ther. 2009; 330: 911-21.
    • (2009) J. Pharmacol. Exp. Ther. , vol.330 , pp. 911-921
    • Lal, R.1    Sukbuntherng, J.2    Tai, E.H.3
  • 34
    • 77953232099 scopus 로고    scopus 로고
    • Arbaclofen placarbil decreases postprandial reflux in patients with gastroesophageal reflux disease
    • Gerson LB, Huff FJ, Hila A etal. Arbaclofen placarbil decreases postprandial reflux in patients with gastroesophageal reflux disease. Am. J. Gastroenterol. 2010; 1266-75.
    • (2010) Am. J. Gastroenterol. , pp. 1266-1275
    • Gerson, L.B.1    Huff, F.J.2    Hila, A.3
  • 35
    • 77955502520 scopus 로고    scopus 로고
    • Effects of lesogaberan on reflux and lower esophageal sphincter function in patients with gastroesophageal reflux disease
    • Boeckxstaens GE, Beaumont H, Mertens V etal. Effects of lesogaberan on reflux and lower esophageal sphincter function in patients with gastroesophageal reflux disease. Gastroenterology 2010; 139: 409-17.
    • (2010) Gastroenterology , vol.139 , pp. 409-417
    • Boeckxstaens, G.E.1    Beaumont, H.2    Mertens, V.3
  • 36
    • 77954455153 scopus 로고    scopus 로고
    • Efficacy and tolerability of the novel reflux inhibitor, AZD3355, As add-on treatment in GERD patients with symptoms despite proton pump inhibitor therapy
    • Boeckxstaens GE, Beaumont H, Hatlebakk JG, Silberg DG, Adler J, Denison H. Efficacy and tolerability of the novel reflux inhibitor, AZD3355, As add-on treatment in GERD patients with symptoms despite proton pump inhibitor therapy. Gastroenterology 2009; 136: A436-A.
    • (2009) Gastroenterology , vol.136
    • Boeckxstaens, G.E.1    Beaumont, H.2    Hatlebakk, J.G.3    Silberg, D.G.4    Adler, J.5    Denison, H.6
  • 37
    • 68849117968 scopus 로고    scopus 로고
    • A proof-of-concept study evaluating the effect of ADX10059, a metabotropic glutamate receptor-5 negative allosteric modulator, on acid exposure and symptoms in gastro-oesophageal reflux disease
    • Keywood C, Wakefield M, Tack J. A proof-of-concept study evaluating the effect of ADX10059, a metabotropic glutamate receptor-5 negative allosteric modulator, on acid exposure and symptoms in gastro-oesophageal reflux disease. Gut 2009; 58: 1192-9.
    • (2009) Gut , vol.58 , pp. 1192-1199
    • Keywood, C.1    Wakefield, M.2    Tack, J.3
  • 38
    • 79952787066 scopus 로고    scopus 로고
    • Randomised clinical trial: effects of monotherapy with ADX10059, a mGluR5 inhibitor, on symptoms and reflux events in patients with gastro-oesophageal reflux disease
    • Zerbib F, Bruley des Varannes S, Roman S etal. Randomised clinical trial: effects of monotherapy with ADX10059, a mGluR5 inhibitor, on symptoms and reflux events in patients with gastro-oesophageal reflux disease. Aliment. Pharmacol. Ther. 2011; 33: 911-21.
    • (2011) Aliment. Pharmacol. Ther. , vol.33 , pp. 911-921
    • Zerbib, F.1    Bruley des Varannes, S.2    Roman, S.3
  • 39
    • 22844451154 scopus 로고    scopus 로고
    • Systematic review: proton-pump inhibitor failure in gastro-oesophageal reflux disease-where next?
    • Fass R, Shapiro M, Dekel R, Sewell J. Systematic review: proton-pump inhibitor failure in gastro-oesophageal reflux disease-where next? Aliment. Pharmacol. Ther. 2005; 22: 79-94.
    • (2005) Aliment. Pharmacol. Ther. , vol.22 , pp. 79-94
    • Fass, R.1    Shapiro, M.2    Dekel, R.3    Sewell, J.4
  • 40
    • 33745789780 scopus 로고    scopus 로고
    • Acid and non-acid reflux in patients with persistent symptoms despite acid suppressive therapy: a multicentre study using combined ambulatory impedance-pH monitoring
    • Mainie I, Tutuian R, Shay S etal. Acid and non-acid reflux in patients with persistent symptoms despite acid suppressive therapy: a multicentre study using combined ambulatory impedance-pH monitoring. Gut 2006; 55: 1398-402.
    • (2006) Gut , vol.55 , pp. 1398-1402
    • Mainie, I.1    Tutuian, R.2    Shay, S.3
  • 41
    • 0033001099 scopus 로고    scopus 로고
    • Antidepressant treatment of patients with diffuse esophageal spasm: a psychosomatic approach
    • Handa M, Mine K, Yamamoto H etal. Antidepressant treatment of patients with diffuse esophageal spasm: a psychosomatic approach. J. Clin. Gastroenterol. 1999; 28: 228-32.
    • (1999) J. Clin. Gastroenterol. , vol.28 , pp. 228-232
    • Handa, M.1    Mine, K.2    Yamamoto, H.3
  • 42
    • 0023143225 scopus 로고
    • Low-dose trazodone for symptomatic patients with esophageal contraction abnormalities. A double-blind, placebo-controlled trial
    • Clouse RE, Lustman PJ, Eckert TC, Ferney DM, Griffith LS. Low-dose trazodone for symptomatic patients with esophageal contraction abnormalities. A double-blind, placebo-controlled trial. Gastroenterology 1987; 92: 1027-36.
    • (1987) Gastroenterology , vol.92 , pp. 1027-1036
    • Clouse, R.E.1    Lustman, P.J.2    Eckert, T.C.3    Ferney, D.M.4    Griffith, L.S.5
  • 43
    • 50949115067 scopus 로고    scopus 로고
    • Pyloric injection of botulinum toxin for the treatment of refractory GERD accompanied with gastroparesis: a preliminary report
    • Mirbagheri SA, Sadeghi A, Amouie M etal. Pyloric injection of botulinum toxin for the treatment of refractory GERD accompanied with gastroparesis: a preliminary report. Dig. Dis. Sci. 2008; 53: 2621-6.
    • (2008) Dig. Dis. Sci. , vol.53 , pp. 2621-2626
    • Mirbagheri, S.A.1    Sadeghi, A.2    Amouie, M.3
  • 46
    • 35748955782 scopus 로고    scopus 로고
    • Clinical trial: persistent gastro-oesophageal reflux symptoms despite standard therapy with proton pump inhibitors-a follow-up study of intraluminal-impedance guided therapy
    • Becker V, Bajbouj M, Waller K, Schmid RM, Meining A. Clinical trial: persistent gastro-oesophageal reflux symptoms despite standard therapy with proton pump inhibitors-a follow-up study of intraluminal-impedance guided therapy. Aliment. Pharmacol. Ther. 2007; 26: 1355-60.
    • (2007) Aliment. Pharmacol. Ther. , vol.26 , pp. 1355-1360
    • Becker, V.1    Bajbouj, M.2    Waller, K.3    Schmid, R.M.4    Meining, A.5
  • 47
    • 49749095620 scopus 로고    scopus 로고
    • Prospective assessment of patient selection for antireflux surgery by combined multichannel intraluminal impedance pH monitoring
    • del Genio G, Tolone S, del Genio F etal. Prospective assessment of patient selection for antireflux surgery by combined multichannel intraluminal impedance pH monitoring. J. Gastrointest. Surg. 2008; 12: 1491-6.
    • (2008) J. Gastrointest. Surg. , vol.12 , pp. 1491-1496
    • del Genio, G.1    Tolone, S.2    del Genio, F.3
  • 48
    • 33845407597 scopus 로고    scopus 로고
    • Combined multichannel intraluminal impedance-pH monitoring to select patients with persistent gastro-oesophageal reflux for laparoscopic Nissen fundoplication
    • Mainie I, Tutuian R, Agrawal A, Adams D, Castell DO. Combined multichannel intraluminal impedance-pH monitoring to select patients with persistent gastro-oesophageal reflux for laparoscopic Nissen fundoplication. Br. J. Surg. 2006; 93: 1483-7.
    • (2006) Br. J. Surg. , vol.93 , pp. 1483-1487
    • Mainie, I.1    Tutuian, R.2    Agrawal, A.3    Adams, D.4    Castell, D.O.5
  • 49
    • 79955626248 scopus 로고    scopus 로고
    • Reflux parameters as modified by laparoscopic fundoplication in 40 patients with heartburn/regurgitation persisting despite PPI therapy: a study using impedance-pH monitoring
    • Frazzoni M, Conigliaro R, Melotti G. Reflux parameters as modified by laparoscopic fundoplication in 40 patients with heartburn/regurgitation persisting despite PPI therapy: a study using impedance-pH monitoring. Dig. Dis. Sci. 2011; 56: 1099-106.
    • (2011) Dig. Dis. Sci. , vol.56 , pp. 1099-1106
    • Frazzoni, M.1    Conigliaro, R.2    Melotti, G.3
  • 50
    • 48549094818 scopus 로고    scopus 로고
    • Antireflux transoral incisionless fundoplication using EsophyX: 12-month results of a prospective multicenter study
    • Cadiere GB, Buset M, Muls V etal. Antireflux transoral incisionless fundoplication using EsophyX: 12-month results of a prospective multicenter study. World J. Surg. 2008; 32: 1676-88.
    • (2008) World J. Surg. , vol.32 , pp. 1676-1688
    • Cadiere, G.B.1    Buset, M.2    Muls, V.3
  • 51
    • 35748968462 scopus 로고    scopus 로고
    • Clinical trial: acupuncture vs. doubling the proton pump inhibitor dose in refractory heartburn
    • Dickman R, Schiff E, Holland A etal. Clinical trial: acupuncture vs. doubling the proton pump inhibitor dose in refractory heartburn. Aliment. Pharmacol. Ther. 2007; 26: 1333-44.
    • (2007) Aliment. Pharmacol. Ther. , vol.26 , pp. 1333-1344
    • Dickman, R.1    Schiff, E.2    Holland, A.3
  • 52
    • 34447500397 scopus 로고    scopus 로고
    • Oesophageal hypersensitivity is associated with features of psychiatric disorders and the irritable bowel syndrome
    • Rubenstein JH, Nojkov B, Korsnes S etal. Oesophageal hypersensitivity is associated with features of psychiatric disorders and the irritable bowel syndrome. Aliment. Pharmacol. Ther. 2007; 26: 443-53.
    • (2007) Aliment. Pharmacol. Ther. , vol.26 , pp. 443-453
    • Rubenstein, J.H.1    Nojkov, B.2    Korsnes, S.3
  • 53
    • 39749135114 scopus 로고    scopus 로고
    • The influence of co-morbid IBS and psychological distress on outcomes and quality of life following PPI therapy in patients with gastro-oesophageal reflux disease
    • Nojkov B, Rubenstein JH, Adlis SA etal. The influence of co-morbid IBS and psychological distress on outcomes and quality of life following PPI therapy in patients with gastro-oesophageal reflux disease. Aliment. Pharmacol. Ther. 2008; 27: 473-82.
    • (2008) Aliment. Pharmacol. Ther. , vol.27 , pp. 473-482
    • Nojkov, B.1    Rubenstein, J.H.2    Adlis, S.A.3


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