Oesophageal hypersensitivity is associated with features of psychiatric disorders and the irritable bowel syndrome

Alimentary Pharmacology and Therapeutics

Volumn 26, Issue 3, 2007, Pages 443-452

  Rubenstein, J H ^a   Nojkov, B ^a   Korsnes, S ^a   Adlis, S A ^b   Shaw, M J ^b   Weinman, B ^a   Inadomi, J M ^c   Saad, R ^a   Chey, W D ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b PARK NICOLLET CLINIC   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROCHLORIC ACID; PROTON PUMP INHIBITOR;

ADULT; ANXIETY; ARTICLE; BALLOON CATHETER; CLINICAL ARTICLE; CONTROLLED STUDY; ESOPHAGEAL HYPERSENSITIVITY; ESOPHAGUS PH; FEMALE; HEARTBURN; HOSTILITY; HUMAN; HYPERSENSITIVITY; INTESTINE DISTENSION; INTESTINE PERFUSION; IRRITABLE COLON; MALE; MENTAL DISEASE; OBSESSIVE COMPULSIVE DISORDER; PARANOIA; PERCEPTIVE THRESHOLD; PERFUSION; PRIORITY JOURNAL; QUESTIONNAIRE; SOMATIZATION; VOLUNTEER;

ADULT; ANXIETY; ESOPHAGEAL DISEASES; FEMALE; HUMANS; IRRITABLE BOWEL SYNDROME; MALE; MIDDLE AGED; PROTON PUMPS; SENSATION DISORDERS; SOMATOFORM DISORDERS;

EID: 34447500397     PISSN: 02692813     EISSN: 13652036     Source Type: Journal    
DOI: 10.1111/j.1365-2036.2007.03393.x     Document Type: Article

References (37)

1. Dent J, El-Serag HB, Wallander MA, Johansson S. Epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut 2005 54 : 710 7.
2. Zerbib F, Roman S, Ropert A, et al. Esophageal pH-impedance monitoring and symptom analysis in GERD: a study in patients off and on therapy. Am J Gastroenterol 2006 101 : 1956 63.
3. Fass R. Focussed clinical review: nonerosive reflux disease. Medscape Gastroenterology. 2001 3 : http://www.medscape.com/viewarticle/407966, posted 26 February 2001.
4. Watson RGP, Tham TCK, Johnston BT, McDougall NI. Double blind cross-over placebo controlled study of omeprazole in the treatment of patients with reflux symptoms and physiological levels of acid reflux - the "sensitive oesophagus". Gut 1997 40 : 587 90.
5. Lind T, Havelund T, Carlsson R, et al. Heartburn without oesophagitis: efficacy of omeprazole therapy and features determining therapeutic response. Scand J Gastroenterol 1997 32 : 974 9.
6. Richter J, Peura D, Benjamin S, Joelsson B, Whipple J. Efficacy of omeprazole for the treatment of symptomatic acid reflux disease without esophagitis. Arch Intern Med 2000 160 : 1810 6.
7. Clouse RE, Richter JE, Heading RC, Janssens J, Wilson JA. Functional esophageal disorders. In : Drossman DA, Corazziari E, Talley NJ, Thompson WG, Whitehead WE, eds. Rome II: The Functional Gastrointestinal Disorders, 2nd edn. Lawrence, KS : Allen Press, 2000 : 247 98.
8. Rodriguez-Stanley S, Robinson M, Earnest DL, Greenwood-Van Meerveld B, Miner PB, Jr. Esophageal hypersensitivity may be a major cause of heartburn. Am J Gastroenterol 1999 94 : 628 31.
9. Trimble KC, Pryde A, Heading RC. Lowered oesophageal sensory thresholds in patients with symptomatic but not excess gastro-oesophageal reflux: evidence for a spectrum of visceral sensitivity in GORD. Gut 1995 37 : 7 12.
10. Richter JE, Barish CF, Castell DO. Abnormal sensory perception in patients with esophageal chest pain. Gastroenterology 1986 91 : 845 52.
11. Howard PJ, Maher L, Pryde A, Heading RC. Symptomatic gastro-oesophageal reflux, abnormal oesophageal acid exposure, and mucosal acid sensitivity are three separate, though related, aspects of gastro-oesophageal reflux disease. Gut 1991 32 : 128 32.
12. Gracely RH, McGrath P, Dubner R. Validity and sensitivity of ratio scales of sensory and affective verbal pain descriptiors: manipulation of affect by diazepam. Pain 1978a 5 : 19 29.
13. Gracely RH, McGrath P, Dubner R. Ratio scales of sensory and affective verbal pain descriptors. Pain 1978b 5 : 5 18.
14. Ladabaum U, Minoshima S, Owyang C. Pathobiology of visceral pain: molecular mechanisms and therapeutic implications V. Central nervous system processing of somatic and visceral sensory signals. Am J Physiol Gastrointest Liver Physiol 2000 279 : G1 6.
15. Shaw M, Talley NJ, Adlis S, Beebe T, Tomshine P, Healey M. Development of a digestive health status instrument: tests of scaling assumptions, structure and reliability in a primary care population. Aliment Pharmacol Ther 1998 12 : 1067 78.
16. Shaw MJ, Beebe TJ, Adlis SA, Talley NJ. Reliability and validity of the digestive health status instrument in samples of community, primary care, and gastroenterology patients. Aliment Pharmacol Ther 2001 15 : 981 7.
17. Derogatis LR, Melisaratos N. The Brief Symptom Inventory: an introductory report. Psychol Med 1983 13 : 595 605.
18. Gandek B, Ware JE, Aaronson NK, et al. Cross-validation of item selection and scoring for the SF-12 Health Survey in nine countries: results from the IQOLA Project. International Quality of Life Assessment. J Clin Epidemiol 1998 51 : 1171 8.
19. Fass R, Naliboff B, Higa L, et al. Differential effect of long-term esophageal acid exposure on mechanosensitivity and chemosensitivity in humans. Gastroenterology 1998 115 : 1363 73.
20. Silverman DHS, Munakata JA, Ennes H, Mandelkern MA, Hoh CK, Mayer EA. Regional cerebral activity in normal and pathological perception of visceral pain. Gastroenterology 1997 112 : 64 72.
21. Avidan B, Sonnenberg A, Giblovich H, Sontag SJ. Reflux symptoms are associated with psychiatric disease. Aliment Pharmacol Ther 2001 15 : 1907 12.
22. Mertz H, Morgan V, Tanner G, et al. Regional cerebral activation in irritable bowel syndrome and control subjects with painful and nonpainful rectal distention. Gastroenterology 2000 118 : 842 8.
23. Whitehead WE, Palsson OS. Is rectal pain sensitivity a biological marker for irritable bowel syndrome: psychological influences on pain perception. Gastroenterology 1998 115 : 1263 71.
24. North CS, Downs D, Clouse RE, et al. The presentation of irritable bowel syndrome in the context of somatization disorder. Clin Gastroenterol Hepatol 2004 2 : 787 95.
25. Miller AR, North CS, Clouse RE, Wetzel RD, Spitznagel EL, Alpers DH. The association of irritable bowel syndrome and somatization disorder. Ann Clin Psychiatry 2001 13 : 25 30.
26. Halder SL, Locke GR 3rd., Talley NJ, et al. Impact of functional gastrointestinal disorders on health-related quality of life: a population-based case-control study. Aliment Pharmacol Ther 2004 19 : 233 42.
27. Trimble KC, Farouk R, Pryde A, Douglas S, Heading RC. Heightened visceral sensation in functional gastrointestinal disease is not site-specific. Evidence for a generalized disorder of gut sensitivity. Dig Dis Sci 1995 40 : 1607 13.
28. Shapiro M, Green C, Bautista JM, et al. Functional heartburn patients demonstrate traits of functional bowel disorder but lack a uniform increase of chemoreceptor sensitivity to acid. Am J Gastroenterol 2006 101 : 1084 91.
29. Bhalla V, Liu J, Puckett JL, Mittal RK. Symptom hypersensitivity to acid infusion is associated with hypersensitivity of esophageal contractility. Am J Physiol Gastrointest Liver Physiol 2004 287 : G65 71.
30. Rao SS, Gregersen H, Hayek B, Summers RW, Christensen J. Unexplained chest pain: the hypersensitive, hyperreactive, and poorly compliant esophagus. Ann Intern Med 1996 124 : 950 8.
31. Vela MF, Camacho-Lobato L, Srinivasan R, Tutuian R, Katz PO, Castell DO. Simultaneous intraesophageal impedance and pH measurement of acid and nonacid gastroesophageal reflux: effect of omeprazole. Gastroenterology 2001 120 : 1599 606.
32. Peghini PL, Katz PO, Castell DO. Imipramine decreases oesophageal pain perception in human male volunteers. Gut 1998 42 : 807 13.
33. Prakash C, Clouse RE. Long-term outcome from tricyclic antidepressant treatment of functional chest pain. Dig Dis Sci 1999 44 : 2373 9.
34. Varia I, Logue E, O'Connor C, et al. Randomized trial of sertraline in patients with unexplained chest pain of noncardiac origin. Am Heart J 2000 140 : 367 72.
35. Chey WD, Nojkov B, Saad R, Rai J, Adlis SA, Shaw MJ. Does the absence of erosive esophagitis really predict a worse response to Proton Pump Inhibitor (PPI) therapy in patients with Gastroesophageal Reflux Disease? Gastroenterology 2006 130 (Suppl. 2 A-179 [Abstract].
36. Bernstein LM, Baker LA. A clinical test for esophagitis. Gastroenterology 1958 34 : 760 81.
37. Sarkar S, Thompson DG, Woolf CJ, Hobson AR, Millane T, Aziz Q. Patients with chest pain and occult gastroesophageal reflux demonstrate visceral pain hypersensitivity which may be partially responsive to acid suppression. Am J Gastroenterol 2004 99 : 1998 2006.