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Volumn 39, Issue 5, 2007, Pages 415-421

Efficacy in intra-oesophageal acid suppression may decrease after 2-year continuous treatment with proton pump inhibitors

Author keywords

Gastro oesophageal reflux disease; Proton pump inhibitors

Indexed keywords

ESOMEPRAZOLE; LANSOPRAZOLE; OMEPRAZOLE; PANTOPRAZOLE; PROTON PUMP INHIBITOR;

EID: 33947721974     PISSN: 15908658     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dld.2007.01.023     Document Type: Article
Times cited : (13)

References (46)
  • 1
    • 13744261420 scopus 로고    scopus 로고
    • Updated guidelines for the diagnosis and treatment of gastroesophageal reflux disease
    • DeVault K.R., and Castell D.O. Updated guidelines for the diagnosis and treatment of gastroesophageal reflux disease. Am J Gastroenterol 100 (2005) 190-200
    • (2005) Am J Gastroenterol , vol.100 , pp. 190-200
    • DeVault, K.R.1    Castell, D.O.2
  • 2
    • 0032816679 scopus 로고    scopus 로고
    • Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification
    • Lundell L.R., Dent J., Bennett J.R., Blum A.L., Armstrong D., Galmiche J.P., et al. Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification. Gut 45 (1999) 172-180
    • (1999) Gut , vol.45 , pp. 172-180
    • Lundell, L.R.1    Dent, J.2    Bennett, J.R.3    Blum, A.L.4    Armstrong, D.5    Galmiche, J.P.6
  • 3
    • 0346433966 scopus 로고    scopus 로고
    • Different patterns of oesophageal acid exposure distinguish complicated reflux disease from either erosive reflux oesophagitis or non-erosive reflux disease
    • Frazzoni M., De Micheli E., and Savarino V. Different patterns of oesophageal acid exposure distinguish complicated reflux disease from either erosive reflux oesophagitis or non-erosive reflux disease. Aliment Pharmacol Ther 18 (2003) 1091-1098
    • (2003) Aliment Pharmacol Ther , vol.18 , pp. 1091-1098
    • Frazzoni, M.1    De Micheli, E.2    Savarino, V.3
  • 4
    • 0032998835 scopus 로고    scopus 로고
    • An evidence-based appraisal of reflux disease management-the Genval Workshop Report
    • Dent J., Brun J., Fendrick A.M., Fennerty M.B., Janssens J., Kahrilas P.J., et al. An evidence-based appraisal of reflux disease management-the Genval Workshop Report. Gut 44 suppl. 2 (1999) S1-S16
    • (1999) Gut , vol.44 , Issue.SUPPL. 2
    • Dent, J.1    Brun, J.2    Fendrick, A.M.3    Fennerty, M.B.4    Janssens, J.5    Kahrilas, P.J.6
  • 5
    • 0037325269 scopus 로고    scopus 로고
    • Overview: initial and long-term management of gastro-oesophageal reflux disease
    • Dent J., and Talley N.J. Overview: initial and long-term management of gastro-oesophageal reflux disease. Aliment Pharmacol Ther 17 Suppl. 1 (2003) 53-57
    • (2003) Aliment Pharmacol Ther , vol.17 , Issue.SUPPL. 1 , pp. 53-57
    • Dent, J.1    Talley, N.J.2
  • 6
    • 1342289063 scopus 로고    scopus 로고
    • Review article: approaches to Barrett's oesophagus treatment-the role of proton pump inhibitors and other interventions
    • Jankowski J., and Sharma P. Review article: approaches to Barrett's oesophagus treatment-the role of proton pump inhibitors and other interventions. Aliment Pharmacol Ther 19 Suppl 1 (2004) 54-59
    • (2004) Aliment Pharmacol Ther , vol.19 , Issue.SUPPL. 1 , pp. 54-59
    • Jankowski, J.1    Sharma, P.2
  • 7
    • 0034064001 scopus 로고    scopus 로고
    • Long-term omeprazole treatment in resistant gastroesophageal reflux disease: efficacy, safety, and influence on gastric mucosa
    • Klinkenberg-Knol E.C., Nelis F., Dent J., Snel P., Mitchell B., Prichard P., et al. Long-term omeprazole treatment in resistant gastroesophageal reflux disease: efficacy, safety, and influence on gastric mucosa. Gastroenterology 118 (2000) 661-669
    • (2000) Gastroenterology , vol.118 , pp. 661-669
    • Klinkenberg-Knol, E.C.1    Nelis, F.2    Dent, J.3    Snel, P.4    Mitchell, B.5    Prichard, P.6
  • 8
    • 0035132772 scopus 로고    scopus 로고
    • Continued (5-year) follow-up of a randomized clinical study comparing antireflux surgery and omeprazole in gastroesophageal reflux disease
    • Lundell L., Miettinen P., Myrvold H.E., Pedersen S.A., Liedman B., Hatlebakk J.G., et al. Continued (5-year) follow-up of a randomized clinical study comparing antireflux surgery and omeprazole in gastroesophageal reflux disease. J Am Coll Surg 192 (2001) 172-179
    • (2001) J Am Coll Surg , vol.192 , pp. 172-179
    • Lundell, L.1    Miettinen, P.2    Myrvold, H.E.3    Pedersen, S.A.4    Liedman, B.5    Hatlebakk, J.G.6
  • 9
    • 0034778474 scopus 로고    scopus 로고
    • Long-term lansoprazole treatment for gastro-oesophageal reflux disease: clinical efficacy and influence on gastric mucosa
    • Geboes K., Dekker W., Mulder C.J.J., and Nusteling K. Long-term lansoprazole treatment for gastro-oesophageal reflux disease: clinical efficacy and influence on gastric mucosa. Aliment Pharmacol Ther 15 (2001) 1819-1826
    • (2001) Aliment Pharmacol Ther , vol.15 , pp. 1819-1826
    • Geboes, K.1    Dekker, W.2    Mulder, C.J.J.3    Nusteling, K.4
  • 10
    • 0037325481 scopus 로고    scopus 로고
    • A randomized, double-blind trial of the efficacy and safety of 10 or 20 mg rabeprazole compared with 20 mg omeprazole in the maintenance of gastro-oesophageal reflux disease over 5 years
    • Thjodleifsson B., Rindi G., Fiocca R., Humphries T.J., Morocutti A., Miller N., et al. A randomized, double-blind trial of the efficacy and safety of 10 or 20 mg rabeprazole compared with 20 mg omeprazole in the maintenance of gastro-oesophageal reflux disease over 5 years. Aliment Pharmacol Ther 17 (2003) 343-351
    • (2003) Aliment Pharmacol Ther , vol.17 , pp. 343-351
    • Thjodleifsson, B.1    Rindi, G.2    Fiocca, R.3    Humphries, T.J.4    Morocutti, A.5    Miller, N.6
  • 11
    • 23844559215 scopus 로고    scopus 로고
    • Long-term prevention of erosive or ulcerative gastro-oesophageal reflux disease relapse with rabeprazole 10 or 20 mg vs. placebo: results of a 5-year study in the United States
    • Caos A., Breiter J., Perdomo C., and Barth J. Long-term prevention of erosive or ulcerative gastro-oesophageal reflux disease relapse with rabeprazole 10 or 20 mg vs. placebo: results of a 5-year study in the United States. Aliment Pharmacol Ther 22 (2005) 193-202
    • (2005) Aliment Pharmacol Ther , vol.22 , pp. 193-202
    • Caos, A.1    Breiter, J.2    Perdomo, C.3    Barth, J.4
  • 12
    • 0035050317 scopus 로고    scopus 로고
    • Stability of gastric secretory inhibition during 6-month treatment with omeprazole in patients with gastroesophageal reflux disease
    • Tefera S., Hatlebakk J.G., and Berstad A. Stability of gastric secretory inhibition during 6-month treatment with omeprazole in patients with gastroesophageal reflux disease. Am J Gastroenterol 96 (2001) 969-974
    • (2001) Am J Gastroenterol , vol.96 , pp. 969-974
    • Tefera, S.1    Hatlebakk, J.G.2    Berstad, A.3
  • 14
    • 0036678111 scopus 로고    scopus 로고
    • Updated guidelines for the diagnosis, surveillance, and therapy of Barrett's esophagus
    • The Practice Parameters Committee of the American College of Gastroenterology
    • Sampliner R.E., and The Practice Parameters Committee of the American College of Gastroenterology. Updated guidelines for the diagnosis, surveillance, and therapy of Barrett's esophagus. Am J Gastroenterol 97 (2002) 1888-1895
    • (2002) Am J Gastroenterol , vol.97 , pp. 1888-1895
    • Sampliner, R.E.1
  • 15
    • 0027177621 scopus 로고
    • Are routine duodenal and antral biopsies useful in the management of "functional" dyspepsia? A diagnostic and therapeutic study
    • Frazzoni M., Lonardo A., Grisendi A., Della Casa G., Pulvirenti M., Ferrari A.M., et al. Are routine duodenal and antral biopsies useful in the management of "functional" dyspepsia? A diagnostic and therapeutic study. J Clin Gastroenterol 17 (1993) 101-108
    • (1993) J Clin Gastroenterol , vol.17 , pp. 101-108
    • Frazzoni, M.1    Lonardo, A.2    Grisendi, A.3    Della Casa, G.4    Pulvirenti, M.5    Ferrari, A.M.6
  • 16
    • 0034085999 scopus 로고    scopus 로고
    • Standards for oesophageal manometry. A position statement from the Gruppo Italiano di Studio Motilità Apparato Digerente (GISMAD)
    • Passaretti S., Zaninotto G., Di Martino N., Leo P., Costantini M., and Baldi F. Standards for oesophageal manometry. A position statement from the Gruppo Italiano di Studio Motilità Apparato Digerente (GISMAD). Dig Liver Dis 32 (2000) 46-55
    • (2000) Dig Liver Dis , vol.32 , pp. 46-55
    • Passaretti, S.1    Zaninotto, G.2    Di Martino, N.3    Leo, P.4    Costantini, M.5    Baldi, F.6
  • 17
    • 0026624817 scopus 로고
    • Normal 24-hour ambulatory esophageal pH values. Influence of study center, pH electrode, age, and gender
    • Richter J.E., Bradley L.A., DeMeester T.R., and Wu W.C. Normal 24-hour ambulatory esophageal pH values. Influence of study center, pH electrode, age, and gender. Dig Dis Sci 37 (1992) 849-856
    • (1992) Dig Dis Sci , vol.37 , pp. 849-856
    • Richter, J.E.1    Bradley, L.A.2    DeMeester, T.R.3    Wu, W.C.4
  • 18
    • 0032782622 scopus 로고    scopus 로고
    • Differentiation and proliferation in Barrett's esophagus and the effects of acid suppression
    • Ouatu-Lascar R., Fitzgerald R.C., and Triadafilopoulos G. Differentiation and proliferation in Barrett's esophagus and the effects of acid suppression. Gastroenterology 117 (1999) 327-335
    • (1999) Gastroenterology , vol.117 , pp. 327-335
    • Ouatu-Lascar, R.1    Fitzgerald, R.C.2    Triadafilopoulos, G.3
  • 19
    • 0036104087 scopus 로고    scopus 로고
    • Definition of reflux disease and its separation from dyspepsia
    • Dent J. Definition of reflux disease and its separation from dyspepsia. Gut 50 Suppl. IV (2002) iv17-iv20
    • (2002) Gut , vol.50 , Issue.SUPPL. IV
    • Dent, J.1
  • 21
    • 3142668886 scopus 로고    scopus 로고
    • Pathophysiological characteristics of patients with non-erosive reflux disease differ from those of patients with functional heartburn
    • Frazzoni M., De Micheli E., Zentilin P., and Savarino V. Pathophysiological characteristics of patients with non-erosive reflux disease differ from those of patients with functional heartburn. Aliment Pharmacol Ther 20 (2004) 81-88
    • (2004) Aliment Pharmacol Ther , vol.20 , pp. 81-88
    • Frazzoni, M.1    De Micheli, E.2    Zentilin, P.3    Savarino, V.4
  • 22
    • 0036164221 scopus 로고    scopus 로고
    • Lansoprazole vs. omeprazole for gastrooesophageal reflux disease: a pH-metric comparison
    • Frazzoni M., De Micheli E., Grisendi A., and Savarino V. Lansoprazole vs. omeprazole for gastrooesophageal reflux disease: a pH-metric comparison. Aliment Pharmacol Ther 16 (2002) 35-40
    • (2002) Aliment Pharmacol Ther , vol.16 , pp. 35-40
    • Frazzoni, M.1    De Micheli, E.2    Grisendi, A.3    Savarino, V.4
  • 23
    • 0037312635 scopus 로고    scopus 로고
    • Effective intra-oesophageal acid suppression in patients with gastro-oesophageal reflux disease: lansoprazole vs. pantoprazole
    • Frazzoni M., De Micheli E., Grisendi A., and Savarino V. Effective intra-oesophageal acid suppression in patients with gastro-oesophageal reflux disease: lansoprazole vs. pantoprazole. Aliment Pharmacol Ther 17 (2003) 235-241
    • (2003) Aliment Pharmacol Ther , vol.17 , pp. 235-241
    • Frazzoni, M.1    De Micheli, E.2    Grisendi, A.3    Savarino, V.4
  • 24
    • 33745401257 scopus 로고    scopus 로고
    • Intra-oesophageal acid suppression in complicated gastro-oesophageal reflux disease: esomeprazole vs. lansoprazole
    • Frazzoni M., Manno M., De Micheli E., and Savarino V. Intra-oesophageal acid suppression in complicated gastro-oesophageal reflux disease: esomeprazole vs. lansoprazole. Dig Liver Dis 38 (2006) 85-90
    • (2006) Dig Liver Dis , vol.38 , pp. 85-90
    • Frazzoni, M.1    Manno, M.2    De Micheli, E.3    Savarino, V.4
  • 25
    • 0026675024 scopus 로고
    • Ambulatory 24-h esophageal pH monitoring: normal values, optimal thresholds, specificity, sensitivity, and reproducibility
    • Jamieson J.R., Stein H.J., DeMeester T.R., Bonavina L., Schwizer W., Hinder R.A., et al. Ambulatory 24-h esophageal pH monitoring: normal values, optimal thresholds, specificity, sensitivity, and reproducibility. Am J Gastroenterol 87 (1992) 1102-1111
    • (1992) Am J Gastroenterol , vol.87 , pp. 1102-1111
    • Jamieson, J.R.1    Stein, H.J.2    DeMeester, T.R.3    Bonavina, L.4    Schwizer, W.5    Hinder, R.A.6
  • 26
    • 0029980832 scopus 로고    scopus 로고
    • Clinical esophageal pH recording: a technical review for practice guideline development
    • Kahrilas P.J., and Quigley E.M.M. Clinical esophageal pH recording: a technical review for practice guideline development. Gastroenterology 110 (1996) 1982-1986
    • (1996) Gastroenterology , vol.110 , pp. 1982-1986
    • Kahrilas, P.J.1    Quigley, E.M.M.2
  • 27
    • 0026513406 scopus 로고
    • Effects of a pH electrode across the lower esophageal sphincter
    • Singh S., and Richter J.E. Effects of a pH electrode across the lower esophageal sphincter. Dig Dis Sci 37 (1992) 667-672
    • (1992) Dig Dis Sci , vol.37 , pp. 667-672
    • Singh, S.1    Richter, J.E.2
  • 28
    • 0346374660 scopus 로고    scopus 로고
    • Delayed gastric emptying in gastroesophageal reflux disease: reassessment with new methods and symptomatic correlations
    • Buckles D.C., Sarosiek I., McMillin C., and McCallum R.W. Delayed gastric emptying in gastroesophageal reflux disease: reassessment with new methods and symptomatic correlations. Am J Med Sci 327 (2004) 1-4
    • (2004) Am J Med Sci , vol.327 , pp. 1-4
    • Buckles, D.C.1    Sarosiek, I.2    McMillin, C.3    McCallum, R.W.4
  • 29
    • 7044232914 scopus 로고    scopus 로고
    • Review article: gastric pH-the most relevant predictor of benefit in reflux disease?
    • Armstrong D. Review article: gastric pH-the most relevant predictor of benefit in reflux disease?. Aliment Pharmacol Ther 20 Suppl. 5 (2004) 19-26
    • (2004) Aliment Pharmacol Ther , vol.20 , Issue.SUPPL. 5 , pp. 19-26
    • Armstrong, D.1
  • 30
    • 0038574407 scopus 로고    scopus 로고
    • CYP2C19 pharmacogenetics in the clinical use of proton-pump inhibitors for gastro-oesophageal reflux disease: variant alleles predict gastric acid suppression, but not oesophageal acid exposure or reflux symptoms
    • Egan L.J., Myhre G.M., Mays D.C., Dierkhising R.A., Kammer P.P., and Murray J.A. CYP2C19 pharmacogenetics in the clinical use of proton-pump inhibitors for gastro-oesophageal reflux disease: variant alleles predict gastric acid suppression, but not oesophageal acid exposure or reflux symptoms. Aliment Pharmacol Ther 17 (2003) 1521-1528
    • (2003) Aliment Pharmacol Ther , vol.17 , pp. 1521-1528
    • Egan, L.J.1    Myhre, G.M.2    Mays, D.C.3    Dierkhising, R.A.4    Kammer, P.P.5    Murray, J.A.6
  • 31
    • 3142708981 scopus 로고    scopus 로고
    • Complete elimination pf reflux symptoms does not guarantee normalization of intraesophageal and intragastric pH in patients with gastroesophageal reflux disease (GERD)
    • Milkes D., Gerson L.B., and Triadafilopoulos G. Complete elimination pf reflux symptoms does not guarantee normalization of intraesophageal and intragastric pH in patients with gastroesophageal reflux disease (GERD). Am J Gastroenterol 98 (2004) 991-996
    • (2004) Am J Gastroenterol , vol.98 , pp. 991-996
    • Milkes, D.1    Gerson, L.B.2    Triadafilopoulos, G.3
  • 32
    • 33748371628 scopus 로고    scopus 로고
    • Gastric and esophageal pH in patients with Barrett's esophagus treated with three esomeprazole dosages: a randomised, double-blind, crossover trial
    • Spechler S.J., Sharma P., Traxler B., Levine D., and Falk J.W. Gastric and esophageal pH in patients with Barrett's esophagus treated with three esomeprazole dosages: a randomised, double-blind, crossover trial. Am J Gastroenterol 101 (2006) 1964-1971
    • (2006) Am J Gastroenterol , vol.101 , pp. 1964-1971
    • Spechler, S.J.1    Sharma, P.2    Traxler, B.3    Levine, D.4    Falk, J.W.5
  • 33
    • 3843089773 scopus 로고    scopus 로고
    • Natural history of gastro-oesophageal reflux disease without oesophagitis (NERD)-a reappraisal 10 years on
    • Pace F., Bollani S., Molteni P., and Bianchi Porro G. Natural history of gastro-oesophageal reflux disease without oesophagitis (NERD)-a reappraisal 10 years on. Dig Liver Dis 36 (2004) 111-115
    • (2004) Dig Liver Dis , vol.36 , pp. 111-115
    • Pace, F.1    Bollani, S.2    Molteni, P.3    Bianchi Porro, G.4
  • 36
    • 33750520550 scopus 로고    scopus 로고
    • Prospective follow-up data from the ProGERD study suggests that GERD is not a categorial disease
    • Labenz J., Nocon M., Lind T., Leodolter A., Jaspersen D., Meyer-Sabellek W., et al. Prospective follow-up data from the ProGERD study suggests that GERD is not a categorial disease. Am J Gastroenterol 101 (2006) 2457-2462
    • (2006) Am J Gastroenterol , vol.101 , pp. 2457-2462
    • Labenz, J.1    Nocon, M.2    Lind, T.3    Leodolter, A.4    Jaspersen, D.5    Meyer-Sabellek, W.6
  • 37
    • 0028256448 scopus 로고
    • Simultaneous two level oesophageal pH monitoring in healthy controls and patients with oesophagitis: comparison between two positions
    • Singh P., Taylor R.H., and Colin-Jones D.G. Simultaneous two level oesophageal pH monitoring in healthy controls and patients with oesophagitis: comparison between two positions. Gut 35 (1994) 304-308
    • (1994) Gut , vol.35 , pp. 304-308
    • Singh, P.1    Taylor, R.H.2    Colin-Jones, D.G.3
  • 38
    • 0029024875 scopus 로고
    • Esophageal aperistalsis and gastroesophageal reflux disorder: return of peristalsis after H2-blocker therapy
    • Meshkinpour H. Esophageal aperistalsis and gastroesophageal reflux disorder: return of peristalsis after H2-blocker therapy. Am J Gastroenterol 90 (1995) 910-914
    • (1995) Am J Gastroenterol , vol.90 , pp. 910-914
    • Meshkinpour, H.1
  • 39
    • 0036107706 scopus 로고    scopus 로고
    • Management of reflux disease
    • Dent J. Management of reflux disease. Gut 50 Suppl. IV (2002) iv67-iv71
    • (2002) Gut , vol.50 , Issue.SUPPL. IV
    • Dent, J.1
  • 40
    • 0242320349 scopus 로고    scopus 로고
    • Comparison of morning and evening administration of rabeprazole for gastro-oesophageal reflux and nocturnal gastric acid breakthrough in patients with reflux disease: a double-blind, cross-over study
    • Pehlivanov N.D., Olyaee M., Sarosiek I., and McCallum R.W. Comparison of morning and evening administration of rabeprazole for gastro-oesophageal reflux and nocturnal gastric acid breakthrough in patients with reflux disease: a double-blind, cross-over study. Aliment Pharmacol Ther 18 (2003) 1-8
    • (2003) Aliment Pharmacol Ther , vol.18 , pp. 1-8
    • Pehlivanov, N.D.1    Olyaee, M.2    Sarosiek, I.3    McCallum, R.W.4
  • 41
    • 1642492959 scopus 로고    scopus 로고
    • Effect of Helicobacter pylori eradication on treatment of gastro-oesophageal reflux disease: a double blind, placebo controlled, randomised trial
    • Wu J.C.Y., Chan F.K.L., Ching J.W.L., Leung W.-K., Hui Y., Leong R., et al. Effect of Helicobacter pylori eradication on treatment of gastro-oesophageal reflux disease: a double blind, placebo controlled, randomised trial. Gut 53 (2004) 174-179
    • (2004) Gut , vol.53 , pp. 174-179
    • Wu, J.C.Y.1    Chan, F.K.L.2    Ching, J.W.L.3    Leung, W.-K.4    Hui, Y.5    Leong, R.6
  • 42
    • 0033967016 scopus 로고    scopus 로고
    • Prospective evaluation of the prevalence of gastric Helicobacter pylori infection in patients with GORD, Barrett's esophagus, Barrett's dysplasia, and Barrett's adenocarcinoma
    • Weston A.P., Badr A.S., Topalovski M., Cherian R., Dixon A., and Hassanein R.S. Prospective evaluation of the prevalence of gastric Helicobacter pylori infection in patients with GORD, Barrett's esophagus, Barrett's dysplasia, and Barrett's adenocarcinoma. Am J Gastroenterol 95 (2000) 387-394
    • (2000) Am J Gastroenterol , vol.95 , pp. 387-394
    • Weston, A.P.1    Badr, A.S.2    Topalovski, M.3    Cherian, R.4    Dixon, A.5    Hassanein, R.S.6
  • 44
    • 0028216695 scopus 로고
    • Successful elimination of reflux symptoms does not insure adequate control of acid reflux in patients with Barrett's esophagus
    • Katzka D.A., and Castell D.O. Successful elimination of reflux symptoms does not insure adequate control of acid reflux in patients with Barrett's esophagus. Am J Gastroenterol 89 (1994) 989-991
    • (1994) Am J Gastroenterol , vol.89 , pp. 989-991
    • Katzka, D.A.1    Castell, D.O.2
  • 45
    • 0032081061 scopus 로고    scopus 로고
    • Complete elimination of reflux symptoms does not guarantee normalization of intraesophageal acid reflux in patients with Barrett's esophagus
    • Ouatu-Lascar R., and Triadafilopoulos G. Complete elimination of reflux symptoms does not guarantee normalization of intraesophageal acid reflux in patients with Barrett's esophagus. Am J Gastroenterol 93 (1998) 711-716
    • (1998) Am J Gastroenterol , vol.93 , pp. 711-716
    • Ouatu-Lascar, R.1    Triadafilopoulos, G.2
  • 46
    • 0029938339 scopus 로고    scopus 로고
    • Relation between oesophageal acid exposure and healing of oesophagitis with omeprazole in patients with severe reflux oesophagitis
    • Holloway R.H., Dent J., Narielvala F., and Mackinnon A.M. Relation between oesophageal acid exposure and healing of oesophagitis with omeprazole in patients with severe reflux oesophagitis. Gut 38 (1996) 649-654
    • (1996) Gut , vol.38 , pp. 649-654
    • Holloway, R.H.1    Dent, J.2    Narielvala, F.3    Mackinnon, A.M.4


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