Particulate matter induces cardiac arrhythmias via dysregulation of carotid body sensitivity and cardiac sodium channels

American Journal of Respiratory Cell and Molecular Biology

Volumn 46, Issue 4, 2012, Pages 524-531

  Wang, Ting ^a   Lang, Gabriel D ^a   Moreno Vinasco, Liliana ^a   Huang, Yong ^b   Goonewardena, Sascha N ^a   Peng, Ying Jie ^b   Svensson, Eric C ^b   Natarajan, Viswanathan ^a   Lang, Roberto M ^b   Linares, Jered D ^a   Breysse, Patrick N ^d   Geyh, Alison S ^d   Samet, Jonathan M ^c   Lussier, Yves A ^b   Dudley, Samuel ^a   Prabhakar, Nanduri R ^b   Garcia, Joe G N ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d The Johns Hopkins University   (United States)

Author keywords

Congestive heart failure; Electromyograms; Heart rate variability; Particulate matter; Ventricular arrhythmia score

Indexed keywords

POTASSIUM CHANNEL; RANOLAZINE; SODIUM CHANNEL NAV1.5; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPIRATION; CARDIOMYOPATHY; CAROTID BODY; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC CODE; GENETIC ENGINEERING; HEART DENERVATION; HEART LEFT VENTRICLE; HEART RATE VARIABILITY; HEART VENTRICLE ARRHYTHMIA; HYPEROXIA; HYPOXIA; IN VIVO STUDY; MOUSE; NITRATION; NONHUMAN; PARTICULATE MATTER; PHENOTYPE; PROTEIN PHOSPHORYLATION; QT PROLONGATION; RESPIRATION DEPRESSION; RESPIRATORY FAILURE; SENSORY NERVE; TRANSGENIC ANIMAL; UNITED STATES;

AIR POLLUTANTS; ANIMALS; ARRHYTHMIAS, CARDIAC; BALTIMORE; BRADYCARDIA; CAROTID BODY; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HEART FAILURE; HEART VENTRICLES; MICE; MICE, INBRED STRAINS; MICE, MUTANT STRAINS; PARTICULATE MATTER; SODIUM CHANNELS;

MUS;

EID: 84859406542     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2011-0213OC     Document Type: Article

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