Mallory-Denk bodies form when EZH2/H3K27me3 fails to methylate DNA in the nuclei of human and mice liver cells

Experimental and Molecular Pathology

Volumn 92, Issue 3, 2012, Pages 318-326

  French, B A ^a   Oliva, J ^b   Bardag Gorce, F ^b   Li, J ^a   Zhong, J ^a   Buslon, V ^a   French, S W ^a  

^a HARBOR UCLA MEDICAL CENTER   (United States)

^b LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE   (United States)

Author keywords

Alcoholic hepatitis, AH; EZH2, enhancer of Zest 2; H3K27me3, trimethylated H3K27; Hepatocellular carcinoma, HCC; MDB, Mallory Denk bodies

Indexed keywords

CYCLIN D1; CYCLINE; KI 67 ANTIGEN; PROTEIN P27; TRANSCRIPTION FACTOR EZH2;

ALCOHOL LIVER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CYCLE ARREST; CELL GROWTH; CELL LEVEL; CELL NUCLEUS; CELL ORGANELLE; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DNA METHYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL; LIVER CELL CARCINOMA; MALLORY DENK BODY; MOUSE; NONHUMAN; PROTEIN LOCALIZATION;

ANIMALS; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELL CYCLE CHECKPOINTS; CELL NUCLEUS; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DNA METHYLATION; DNA-BINDING PROTEINS; HEPATITIS, ALCOHOLIC; HEPATOCYTES; HISTONES; HUMANS; IMMUNOHISTOCHEMISTRY; LIVER; LIVER NEOPLASMS; LYSINE; MALLORY BODIES; METHYLATION; MICE; MICROSCOPY, ELECTRON; PROLIFERATING CELL NUCLEAR ANTIGEN; PYRIDINES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; S-ADENOSYLMETHIONINE; TRANSCRIPTION FACTORS;

MUS;

EID: 84859401453     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2012.02.003     Document Type: Article

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