Induction of immune responses in sheep by vaccination with liposome-entrapped DNA complexes encoding Toxoplasma gondii MIC3 gene

Polish Journal of Veterinary Sciences

Volumn 15, Issue 1, 2012, Pages 3-9

  Hiszczynska Sawicka E ^a,c   Li, H ^a   Boyu Xu, J ^a   Akhtar, M ^b   Holec Gasior L ^c   Kur, J ^c   Bickerstaffe, R ^a   Stankiewicz, M ^a  

^a LINCOLN UNIVERSITY   (New Zealand)

^b UNIVERSITY OF AGRICULTURE   (Pakistan)

^c GDANSK UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

DNA vaccine; MIC3 antigen; Toxoplasma gondii

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN G; LIPOSOME; MIC3 PROTEIN, TOXOPLASMA GONDII; PROTOZOAL DNA; PROTOZOAL PROTEIN; PROTOZOAL VACCINE; PROTOZOON ANTIBODY;

ANIMAL; ARTICLE; BLOOD; CHO CELL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HAMSTER; IMMUNOLOGY; METABOLISM; RANDOMIZED CONTROLLED TRIAL; SHEEP; SHEEP DISEASE; TOXOPLASMA; TOXOPLASMOSIS; VACCINATION;

ANIMALS; ANTIBODIES, PROTOZOAN; CHO CELLS; CRICETINAE; DNA, PROTOZOAN; GENE EXPRESSION REGULATION; IMMUNOGLOBULIN G; INTERFERON-GAMMA; LIPOSOMES; PROTOZOAN PROTEINS; PROTOZOAN VACCINES; SHEEP; SHEEP DISEASES; TOXOPLASMA; TOXOPLASMOSIS, ANIMAL; VACCINATION;

ANIMALIA; OVIS ARIES; TOXOPLASMA GONDII;

EID: 84859390073     PISSN: 15051773     EISSN: None     Source Type: Journal    
DOI: 10.2478/v10181-011-0107-7     Document Type: Article

References (28)

1. Beghetto E, Nielsen HV, Del Porto P, Buffolano W, Gug-lietta S, Felici F, Petersen E, Gargano N (2005) A combination of antigenic regions of Toxoplasma gondii microneme proteins induces protective immunity against oral infection with parasite cysts. J Infect Dis 191: 637-645. (Pubitemid 40216681)
2. Belaková J, Horynová M, Krupka M, Weigl E, Raska M (2007) DNA vaccines: are they still just a powerful tool for the future? Arch Immunol Ther Exp (Warsz) 55: 387-398.
3. Buxton D, Maley SW, Wright SE, Rodger S, Bartley P, Innes EA (2007) Toxoplasma gondii and ovine toxoplasmosis: new aspects of an old story. Vet Parasitol 149: 25-28. (Pubitemid 47391130)
4. Cerede O, Dubremetz JF, Bout D, Lebrun M (2002) The Toxoplasma gondii protein MIC3 requires pro-peptide cleavage and dimerization to function as adhesin. EMBO J 21: 2526-2536. (Pubitemid 34619369)
5. Chardès T, Bourguin I, Mévéléc MN, Dubremetz JF, Bout D (1990) Antibody responses to Toxoplasma gondii in sera, intestinal secretions and milk from orally infected mice and characterization of target antigens. Infect Im-mun 58: 1240-1246. (Pubitemid 20151783)
6. Dautu G, Munyaka B, Carmen G, Zhang G, Omata Y, Xuenan X, Igarashi M (2007) Toxoplasma gondii: DNA vaccination with genes encoding antigens MIC2, M2AP, AMA1 and BAG1 and evaluation of their immunogenic potential. Exp Parasitol 116: 273-282. (Pubitemid 46709897)
7. Gazzinelli RT, Amichay D, Sharton-Kersten T, Grunwald E, Farber JM, Sher A (1996) Role of macrophage-derived cytokines in the induction and regulation of cell-mediated immunity to Toxoplasma gondii. Curr Top Microbiol Immunol 219: 127-139. (Pubitemid 26272951)
8. Hiszczyńska-Sawicka E, Brillowska-Da̧browska A, Da̧browski S, Pietkiewicz H, Myjak P, Kur J (2003) High yield expression and single-step purification of Toxoplasma gondii SAG1, GRA1 and GRA7 antigens in Escherichia coli. Prot Expr Purif 27: 150-157. (Pubitemid 37096481)
9. Hiszczyńska-Sawicka E, Kur J, Pietkiewicz H, Holec L, Gasior A, Myjak P (2005) Efficient production of the Toxoplasma gondii GRA6, p35 and SAG2 recombinant antigens and their applications in the serodiagnosis of toxoplasmosis. Acta Parasitol 50: 249-254. (Pubitemid 41463294)
10. Hiszczyńska-Sawicka E, Li H, Xu JB, Olȩdzka G, Kur J, Bickerstaffe R, Stankiewicz M (2010a) Comparison of immune response in sheep immunized with DNA vaccine encoding Toxoplasma gondii GRA7 antigen in different adjuvant formulations. Exp Parasitol 124: 365-372.
11. Hiszczyńska-Sawicka E, Akhtar M, Kay GW, Holec-Gasior L, Bickerstaffe R, Kur J, Stankiewicz M (2010b) The immune responses of sheep after DNA immunization with Toxoplasma gondii MAGI antigen - with and without co-expression of ovine interleukin 6. Vet Immunol Immunopathol 136: 324-329.
12. Holec-Ga̧sior L, Kur J, Hiszczyńska-Sawicka E (2009) GRA2 and ROP1 recombinant antigens as potential markers for detection of Toxoplasma gondii - specific immunoglobulin G in humans with acute toxoplasmosis. Clin Vaccine Immunol 16: 510-514.
13. Ismael AB, Sekkai D, Collin C, Bout D, Mevelec MN (2003) The MIC3 gene of Toxoplasma gondii is a novel potent vaccine candidate against toxoplasmosis. Infect Immun 71: 6222-6228. (Pubitemid 37337678)
14. Ismael AB, Dimier-Poisson I, Lebrun M, Dubremetz JF, Bout D, Mevelec MN (2006) Micl-3 knockout of Toxoplasma gondii is a successful vaccine against chronic and congenital toxoplasmosis in mice. J Infect Dis 194: 1176-1183. (Pubitemid 44547659)
15. Johnson LL, Sayles PC (2002) Deficient humoral responses underlie susceptibility to Toxoplasma gondii in CD-4 deficient mice. Infect Immun 70: 185-191. (Pubitemid 34028616)
16. Kang H, Remington JS, Suzuki Y (2000) Decreased resistance of B cell-deficient mice to infection with Toxoplasma gondii despite unimpaired expression of IFN-γ, TNF-α, and inducible nitric oxide synthase. J Immunol 164: 2629-2634. (Pubitemid 30115494)
17. Kur J, Holec-Ga̧sior L, Hiszczyńska-Sawicka E (2009) Current status of toxoplasmosis vaccine development. Expert Rev Vaccines 8: 791-808.
18. McLeod R, Mack DG (1986) Secretory IgA specific for Toxoplasma gondii. J Immunol 136: 2640-2643. (Pubitemid 16136851)
19. Mévéléc MN, Ducournau C, Bassuny Ismael A, Olivier M, Sèche E, Lebrun M, Bout D, Dimier-Poisson I (2010) Micl-3 Knockout Toxoplasma gondii is a good candidate for a vaccine against T. gondii-m&VLced abortion in sheep. Vet Res 41: 49.
20. Payne RW (2009) The Guide to GenStat® Release 12, Part 2: Statistics. VSN International, Hemel Hempstead.
21. Pietkiewicz H, Hiszczyńska-Sawicka E, Kur J, Petersen E, Nielsen HV, Stankiewicz M, Andrzejewska I, Myjak P (2004) Usefulness of Toxoplasma gondii-recombinant antigens in scrodiagnosis of human toxoplasmosis. J Clin Microbiol 42: 1779-1781. (Pubitemid 38500839)
22. Pontarollo RA, Rankin R, Babiuk LA., Godson DL, Griebel PJ, Hecker R, Krieg AM, van Drunen Littel-van den Hurk S (2002) Monocytes are required for optimum in vitro stimulation of bovine peripheral blood mononuclear cells by non-methylated CpG motifs. Vet Immunol Im-munopathol 84: 43-59. (Pubitemid 34083578)
23. Qu D, Yu H, Wang S, Cai W, Du A (2009) Induction of protective immunity by multiantigenic DNA vaccine delivered in attenuated Salmonella typhimurium against Toxoplasma gondii infection in mice. Vet Parasitol 166: 220-227.
24. Soldati D, Dubremetz JF, Lebrun M (2001) Microneme proteins: structural and functional requirements to promote adhesion and invasion by the apicomplexan parasite Toxoplasma gondii. Int J Parasitol 31: 1293-1302. (Pubitemid 32868709)
25. Suzuki Y, Orellana MA, Schreiber RD, Remington JS (1988) Interferon-gamma: the major mediator of resistance against Toxoplasma gondii. Science 240: 516-518.
26. Tomley FM, Soldati DS (2001) Mix and match modules: structure and function of microneme proteins in apicomplexan parasites. Trends Parasitol 17: 81-88. (Pubitemid 32416554)
27. Wood PR, Jones SL (2001) BOVIGAM: an in vitro cellular diagnostic test for bovine tuberculosis. Tuberculosis (Edinb) 81: 147-155. (Pubitemid 32500101)
28. Xiang W, Qiong Z, Li-Peng L, Kui T, Jian-Wu G, Heng-Ping S (2009) The location of invasion-related protein MIC3 of Toxoplasma gondii and protective effect of its DNA vaccine in mice Vet Parasitol 166: 1-7.