A systems approach to model the relationship between aflatoxin gene cluster expression, environmental factors, growth and toxin production by Aspergillus flavus

Journal of the Royal Society Interface

Volumn 9, Issue 69, 2012, Pages 757-767

  Abdel Hadi, Ahmed ^a   Schmidt Heydt, Markus ^b   Parra, Roberto ^c   Geisen, Rolf ^b   Magan, Naresh ^a  

^a CRANFIELD UNIVERSITY   (United Kingdom)

^b FEDERAL RESEARCH INSTITUTE OF NUTRITION AND FOOD   (Germany)

^c SCHOOL OF ENGINEERING AND SCIENCES   (Mexico)

Author keywords

Aflatoxin genes; Aflatoxins; Predictive modelling; Systems biology; Temperature; Water activity

Indexed keywords

ACTIVATION ANALYSIS; AFLATOXINS; ASPERGILLUS; BIOSYNTHESIS; CLIMATE CHANGE; FACTOR ANALYSIS; FOOD PRODUCTS; FORECASTING; SUGAR (SUCROSE); TEMPERATURE;

AFLATOXIN B; ASPERGILLUS FLAVUS; BIOSYNTHETIC GENE; BIOSYNTHETIC PATHWAY; DATA SETS; ENVIRONMENTAL FACTORS; GENE CLUSTERS; GENE EXPRESSION DATA; GROWTH DATA; INTEGRATED SYSTEMS; LINEAR COMBINATIONS; MICROARRAY ANALYSIS; MODEL FITTING; PHYSICAL MODEL; PREDICTIVE MODELLING; PRODUCT FORMATION; REGULATORY GENES; RELATIVE GROWTH RATE; STRUCTURAL GENE; SYSTEMS APPROACH; SYSTEMS BIOLOGY; TEMPERATURE CONDITIONS; TERNARY DIAGRAMS; TOXIN PRODUCTION; WATER ACTIVITY; YEAST EXTRACTS;

GENE EXPRESSION;

AFLATOXIN; AFLATOXIN B1; AFLATOXIN D; AFLATOXIN E; AFLATOXIN F; AFLATOXIN M; AFLATOXIN O; AFLATOXIN P; AFLATOXIN Q; AFLATOXIN R; AFLATOXIN S; AFLATOXIN X; UNCLASSIFIED DRUG;

ARTICLE; ASPERGILLUS FLAVUS; BIOSYNTHESIS; CLIMATE CHANGE; ECOPHYSIOLOGY; ENVIRONMENTAL FACTOR; FUNGUS GROWTH; GENE CLUSTER; GENE EXPRESSION; GROWTH RATE; LINEAR REGRESSION ANALYSIS; MICROARRAY ANALYSIS; MIXED GROWTH ASSOCIATED PRODUCT FORMATION MODEL; MOLECULAR PHYLOGENY; NONHUMAN; PHENOTYPE; PHYSICAL MODEL; PREDICTION; REGULATOR GENE; STRUCTURAL GENE; TEMPERATURE; TOXIN SYNTHESIS; WATER AVAILABILITY; YEAST;

ASPERGILLUS FLAVUS;

EID: 84859389634     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2011.0482     Document Type: Article

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