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MedChemComm

Volumn 3, Issue 4, 2012, Pages 506-511

A solid-phase method for peptide-siRNA covalent conjugates based on click chemistry

(5) Liu, Yang a Wang, Xiao Feng a Chen, Yue a Zhang, Li He a Yang, Zhen Jun a

a PEKING UNIVERSITY HEALTH SCIENCE CENTER (China)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3 TRIAZOLE DERIVATIVE; ALKYNYL NUCLEOSIDE; ANTISENSE OLIGONUCLEOTIDE; CELL PENETRATING PEPTIDE; DEOXYURIDINE DERIVATIVE; NUCLEOSIDE; RNA INDUCED SILENCING COMPLEX; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; CHROMATOGRAPHY; CLICK CHEMISTRY; CONJUGATION; COVALENT BOND; DRUG DELIVERY SYSTEM; GENE SILENCING; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NUCLEOTIDE METABOLISM; PRIORITY JOURNAL; RNA INTERFERENCE; SOLID PHASE SYNTHESIS; THIN LAYER CHROMATOGRAPHY;

EID: 84859387137 PISSN: 20402503 EISSN: 20402511 Source Type: Journal
DOI: 10.1039/c2md00198e Document Type: Article

Times cited : (18)

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- To minimize RNase degradation of the oligoribonucleotide, wearing gloves and sterile materials were necessary during the purification, and all used water was treated by DEPC

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