Therapeutic effect of carboxymethylated and quanternized chitosan on insulin resistance in high-fat-diet-induced rats and 3T3-L1 adipocytes

Journal of Biomaterials Science, Polymer Edition

Volumn 23, Issue 10, 2012, Pages 1271-1284

  Liu, Xiaofei ^a   Yang, Fan ^a   Song, Tao ^a   Zeng, Anrong ^a   Wang, Qi ^a   Sun, Zhong ^b   Shen, Jun ^b  

^a TIANJIN UNIVERSITY   (China)

^b TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Adipocytokines; Chitosan; Derivatives; Insulin resistance; PPAR

Indexed keywords

3T3-L1 ADIPOCYTES; ADIPOCYTOKINES; ADIPONECTIN; BIOAPPLICATIONS; BIOCHEMICAL PROPERTIES; IN-VITRO; IN-VIVO; INSULIN RESISTANCE; LIPID BINDING; MRNA EXPRESSION; O-CARBOXYMETHYL CHITOSANS; RAT MODEL; RESISTIN; THERAPEUTIC EFFECTS;

CHLORINE COMPOUNDS; CHOLESTEROL; DERIVATIVES; GLUCOSE; INSULIN; NUTRITION; POLYMERASE CHAIN REACTION;

CHITOSAN;

ADIPOCYTOKINE; ADIPONECTIN; CARBOXYMETHYL CHITOSAN; CHITOSAN; CHITOSAN DERIVATIVE; CHOLESTEROL; GLUCOSE; INSULIN; LEPTIN; MESSENGER RNA; N [(2 HYDROXY 3 N,N DIMETHYLHEXADECYL AMMONIUM)PROPYL]CHITOSAN CHLORIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RESISTIN; UNCLASSIFIED DRUG; ANTIOBESITY AGENT; N-((2-HYDROXY-3-N,N-DIMETHYLHEXADECYLAMMONIUM)PROPYL)CHITOSAN CHLORIDE; O-CARBOXYMETHYLCHITOSAN;

ADIPOCYTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; CARBOXYMETHYLATION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; DRUG SOLUBILITY; DRUG STRUCTURE; GLUCOSE BLOOD LEVEL; HORMONE BLOOD LEVEL; IN VITRO STUDY; IN VIVO STUDY; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; LEPTIN BLOOD LEVEL; LIPID DIET; MALE; METHYLATION; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; UPREGULATION; 3T3 CELL LINE; ADVERSE EFFECTS; ANALOGS AND DERIVATIVES; ANIMAL; DISEASE MODEL; DRUG EFFECTS; METABOLISM; MOUSE; OBESITY; PATHOPHYSIOLOGY; RANDOMIZATION; WISTAR RAT;

RATTUS;

3T3 CELLS; ADIPOCYTES; ADIPONECTIN; ANIMALS; ANTI-OBESITY AGENTS; CHITOSAN; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; INSULIN RESISTANCE; LEPTIN; MALE; MICE; OBESITY; PPAR GAMMA; RANDOM ALLOCATION; RATS, WISTAR; RESISTIN; RNA, MESSENGER;

EID: 84859386348     PISSN: 09205063     EISSN: 15685624     Source Type: Journal    
DOI: 10.1163/092050611X579771     Document Type: Article

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