Use of hybrid chitosan membranes and N1E-115 cells for promoting nerve regeneration in an axonotmesis rat model

Biomaterials

Volumn 29, Issue 33, 2008, Pages 4409-4419

  Amado, S ^a   Simoes M J ^b   Armada da Silva, P A S ^a   Luis A L ^b   Shirosaki, Y ^b   Lopes, M A ^b   Santos, J D ^b   Fregnan, F ^c   Gambarotta, G ^c   Raimondo, S ^c   Fornaro, M ^c   Veloso, A P ^a   Varejao A S P ^d   Mauricio A C ^b   Geuna, S ^c  

^a UNIVERSITY OF LISBON   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c UNIVERSITY OF TURIN   (Italy)

^d UNIVERSITY OF TRÁS OS MONTES AND ALTO DOURO   (Portugal)

Author keywords

Animal model; Chitosan; Nerve; Nerve regeneration; Nerve tissue engineering

Indexed keywords

ABERRATIONS; BIOCOMPATIBILITY; CELL MEMBRANES; CELLS; CHITIN; CHITOSAN; CYTOLOGY; ENHANCED RECOVERY; FIBER OPTICS; HEALTH; MEMBRANES; OPTICAL PROPERTIES; SURGERY;

ANIMAL MODEL; CELL SURVIVALS; CELLULAR SYSTEMS; CHITOSAN MEMBRANES; CLINICAL OUTCOME; ELECTRON MICROSCOPY.; FIBER REGENERATION; FUNCTIONAL RECOVERY; IN-VITRO; IN-VIVO; NERVE; NERVE REGENERATION; NERVE TISSUE ENGINEERING; NEURAL CELLS; PERIPHERAL NERVES; RAT MODELS; RAT SCIATIC NERVE; STEREOLOGICAL ANALYSIS;

AMINES;

CHITOSAN;

ANIMAL CELL; ANKLE; ARTICLE; BIOCOMPATIBILITY; CELL DIFFERENTIATION; CELL STRAIN; CELL SURVIVAL; ELECTRON MICROSCOPY; IN VITRO STUDY; KINEMATICS; MEMBRANE; NERVE CELL; NERVE FIBER REGENERATION; NERVE REGENERATION; NONHUMAN; PRIORITY JOURNAL; RAT; SCIATIC NERVE; WITHDRAWAL REFLEX;

ANIMALS; AXONS; BIOCOMPATIBLE MATERIALS; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CHITOSAN; CLONE CELLS; MEMBRANES, ARTIFICIAL; MICE; MICROSCOPY, ELECTRON, SCANNING; MODELS, ANIMAL; NERVE CRUSH; NERVE REGENERATION; NEUROBLASTOMA; RATS; RATS, WISTAR; RECOVERY OF FUNCTION; SCIATIC NERVE;

ANIMALIA; RATTUS;

EID: 50849133871     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2008.07.043     Document Type: Article

References (55)

1. Schlosshauer B., Dreesmann L., Schaller H.E., and Sinis N. Synthetic nerve guide implants in humans: a comprehensive survey. Neurosurgery 59 (2006) 740-747
2. Samii M., Carvalho G.A., Nikkhah G., and Penkert G. Surgical reconstruction of the musculocutaneous nerve in traumatic brachial plexus injuries. J Neurosurg 87 (1997) 881-886
3. Lundborg G. Enhancing post-traumatic nerve regeneration. J Peripher Nerv Syst 7 (2002) 139-140
4. Geuna S., Papalia I., and Tos P. End-to-side (terminolateral) nerve regeneration: a challenge for neuroscientists coming from an intriguing nerve repair concept. Brain Res Rev 52 (2006) 381-388
5. Hoke A. Mechanisms of Disease: what factors limit the success of peripheral nerve regeneration in humans?. Nat Clin Pract Neurol 2 (2006) 448-454
6. Mackinnon S.E., Hudson A.R., and Hunter D.A. Histologic assessment of nerve regeneration in the rat. Plast Reconstr Surg 75 (1985) 384-388
7. Meek M.F., Robinson P.H., Stokroos I., Blaauw E.H., Kors G., and den Dunnen W.F. Electronmicroscopical evaluation of short-term nerve regeneration through a thin-walled biodegradable poly(DLLA-epsilon-CL) nerve guide filled with modified denatured muscle tissue. Biomaterials 22 (2001) 1177-1185
8. Battiston B., Geuna S., Ferrero M., and Tos P. Nerve repair by means of tubulization: literature review and personal clinical experience comparing biological and synthetic conduits for sensory nerve repair. Microsurgery 25 (2005) 258-267
9. Chalfoun C.T., Wirth G.A., and Evans G.R. Tissue engineered nerve constructs: where do we stand?. J Cell Mol Med 10 (2006) 309-317
10. Lineaweaver W.C. Size and distance. Microsurgery 27 (2007) 581-582
11. Freier T., Montenegro R., Shan Koh H., and Shoichet M.S. Chitin-based tubes for tissue engineering in the nervous system. Biomaterials 26 (2005) 4624-4632
12. Geuna S., Nicolino S., Raimondo S., Gambarotta G., Battiston B., Tos P., et al. Nerve regeneration along bioengineered scaffolds. Microsurgery 27 (2007) 429-438
13. Lee J.M., Tos P., Raimondo S., Fornaro M., Papalia I., Geuna S., et al. Lack of topographic specificity in nerve fiber regeneration of rat forelimb mixed nerves. Neuroscience 144 (2007) 985-990
14. Tos P., Battiston B., Nicolino S., Raimondo S., Fornaro M., Lee J.M., et al. Comparison of fresh and predegenerated muscle-vein-combined guides for the repair of rat median nerve. Microsurgery 27 (2007) 48-55
15. Chen G., Ushida T., and Tateishi T. Development of biodegradable porous scaffolds for tissue engineering. Mat Sci Eng C 17 (2001) 63-69
16. Chandy T., and Sharma C.P. Chitosan as a biomaterial. Biomater Artif Cells Artif Organs 18 (1990) 1-24
17. Yamaguchi I., Itoh S., Suzuki M., Osaka A., and Tanaka J. The chitosan prepared from crab tendons: II. The chitosan/apatite composites and their application to nerve regeneration. Biomaterials 24 (2003) 3285-3292
18. Yuan Y., Zhang P., Yang Y., Wang X., and Gu X. The interaction of Schwann cells with chitosan membranes and fibers in vitro. Biomaterials 25 (2004) 4273-4278
19. Ishikawa N., Suzuki Y., Ohta M., Cho H., Suzuki S., Dezawa M., et al. Peripheral nerve regeneration through the space formed by a chitosan gel sponge. J Biomed Mater Res A 83 (2007) 33-40
20. Wang W., Itoh S., Matsuda A., Ichinose S., Shinomiya K., Hata Y., et al. Influences of mechanical properties and permeability on chitosan nano/microfiber mesh tubes as a scaffold for nerve regeneration. J Biomed Mater Res A 84 (2008) 557-566
21. Senel S., and McClure S.J. Potential applications of chitosan in veterinary medicine. Adv Drug Del Rev 56 (2004) 1467-1480
22. Shirosaki Y., Tsuru K., Hayakawa S., Osaka A., Lopes M.A., Santos J.D., et al. In vitro cytocompatibility of MG63 cells on chitosan-organosiloxane hybrid membranes. Biomaterials 26 (2005) 485-493
23. Lundborg G., Dahlin L., Danielsen N., and Zhao Q. Trophism, tropism, and specificity in nerve regeneration. J Reconstr Microsurg 10 (1994) 345-354
24. Schmidt C.E., and Leach J.B. Neural tissue engineering: strategies for repair and regeneration. Annu Rev Biomed Eng 5 (2003) 293-347
25. Kimhi Y., Palfrey C., Spector I., Barak Y., and Littauer U.Z. Maturation of neuroblastoma cells in the presence of dimethylsulfoxide. Proc Natl Acad Sci U S A 73 (1976) 462-466
26. Beer G.M., Steurer J., and Meyer V.E. Standardizing nerve crushes with a non-serrated clamp. J Reconstr Microsurg 17 (2001) 531-534
27. Varejão A.S., Cabrita A.M., Meek M.F., Bulas-Cruz J., Melo-Pinto P., Raimondo S., et al. Functional and morphological assessment of a standardized rat sciatic nerve crush injury with a non-serrated clamp. J Neurotrauma 21 (2004) 1652-1670
28. Luís A.L., Amado S., Geuna S., Rodrigues J.M., Simões M.J., Santos J.D., et al. Long-term functional and morphological assessment of a standardized rat sciatic nerve crush injury with a non-serrated clamp. J Neurosci Methods 163 (2007) 92-104
29. Marreco P.R., da Luz Moreira P., Genari S.C., and Moraes A.M. Effects of different sterilization methods on the morphology, mechanical properties, and cytotoxicity of chitosan membranes used as wound dressings. J Biomed Mater Res B Appl Biomater 71 (2004) 268-277
30. Amano T., Richelson E., and Nirenberg M. Neurotransmitter synthesis by neuroblastoma clones (neuroblast differentiation-cell culture-choline acetyltransferase-acetylcholinesterase-tyrosine hydroxylase-axons-dendrites). Proc Natl Acad Sci U S A 69 (1972) 258-263
31. Tuttle J.B., and Richelson E. Phenytoin action on the excitable membrane of mouse neuroblastoma. J Pharmacol Exp Ther 211 (1979) 632-637
32. Fischer S., Domansk L., and Roland R. Muscarinic receptors regulation of cytoplasmatic calcium concentration in human SK-N-Sh neuroblastoma cells: calcium requirements for phospholipase C activation. Mol Pharmacol 35 (1989) 195-204
33. Luís A.L., Rodrigues J.M., Amado S., Veloso A.P., Armada-Da-Silva P.A., Raimondo S., et al. PLGA 90/10 and caprolactone biodegradable nerve guides for the reconstruction of the rat sciatic nerve. Microsurgery 27 (2007) 125-137
34. Sporel-Ozakat R.E., Edwards P.M., Hepgul K.T., Savas A., and Gispen W.H. A simple method for reducing autotomy in rats after peripheral nerve lesions. J Neurosci Methods 36 (1991) 263-265
35. Luís A.L., Rodrigues J.M., Geuna S., Amado S., Shirosaki Y., Lee J.M., et al. Use of PLGA 90:10 scaffolds enriched with in vitro-differentiated neural cells for repairing rat sciatic nerve defects. Tissue Eng Part A 14 (2008) 979-993
36. Luís AL, Rodrigues JM, Geuna S, Amado S, Simões MJ, Fregnan F, et al. Neural cell transplantation effects on sciatic nerve regeneration after a standardized crush injury in the rat. Microsurgery, in press, doi:10.1002/micr.
37. Koka R., and Hadlock T.A. Quantification of functional recovery following rat sciatic nerve transection. Exp Neurol 168 (2001) 192-195
38. Masters D., Berde C., Dutta S., Griggs C., Hu D., Kupsky W., et al. Prolonged regional nerve blockade by controlled release of local anesthetic from a biodegradable polymer matrix. Anesthesiology 79 (1993) 340-346
39. Hu D., Hu R., and Berde C. Neurologic evaluation of infant and adult rats before and after sciatic nerve blockade. Anesthesiology 86 (1997) 957-965
40. Varejão A.S., Cabrita A.M., Geuna S., Patricio J.A., Azevedo H.R., Ferreira A.J., et al. Functional assessment of sciatic nerve recovery: biodegradable poly (DLLA-epsilon-CL) nerve guide filled with fresh skeletal muscle. Microsurgery 23 (2003) 346-353
41. Bain J.R., Mackinnon S.E., and Hunter D.A. Functional evaluation of complete sciatic, peroneal, and posterior tibial nerve lesions in the rat. Plast Reconstr Surg 83 (1989) 129-138
42. Bervar M. Video analysis of standing-an alternative footprint analysis to assess functional loss following injury to the rat sciatic nerve. J Neurosci Methods 102 (2000) 109-116
43. Dijkstra J.R., Meek M.F., Robinson P.H., and Gramsbergen A. Methods to evaluate functional nerve recovery in adult rats: walking track analysis, video analysis and the withdrawal reflex. J Neurosci Methods 96 (2000) 89-96
44. Clarke K.A., and Parker A.J. A quantitative study of normal locomotion in the rat. Physiol Behav 38 (1986) 345-351
45. Varejão A.S., Cabrita A.M., Meek M.F., Bulas-Cruz J., Gabriel R.C., Filipe V.M., et al. Motion of the foot and ankle during the stance phase in rats. Muscle Nerve 26 (2002) 630-635
46. Di Scipio F., Raimondo S., Tos P., and Geuna S. A simple protocol for paraffin-embedded myelin sheath staining with osmium tetroxide for light microscope observation. Microsc Res Tech 71 (2008) 497-502
47. Geuna S., Gigo-Benato D., and Rodrigues A.C. On sampling and sampling errors in histomorphometry of peripheral nerve fibers. Microsurgery 24 (2004) 72-76
48. Schmitz C. Variation of fractionator estimates and its prediction. Anat Embryol (Berl) 198 (1998) 371-397
49. Varejão A.S.P., Melo-Pinto P., Meek M.F., Filipe V.M., and Bulas-Cruz J. Methods for the experimental functional assessment of rat sciatic nerve regeneration. Neurol Res 26 (2004) 186-194
50. Mackinnon S.E., Dellon A.L., and O'Brien J.P. Changes in nerve fiber numbers distal to a nerve repair in the rat sciatic nerve model. Muscle Nerve 14 (1991) 1116-1122
51. Hench L.L., and Ethridge E.C. Biomaterials An Interfacial Approach (1982), Academic Press, New York p. 10
52. Tateishi T., Chen G., and Ushida T. Biodegradable porous scaffolds for tissue engineering. J Artif Organs 5 (2002) 77-83
53. Kuhn G., Lie A., Wilms S., and Muller H.W. Coexpression of PMP22 gene with MBP and P0 during de novo myelination and nerve repair. Glia 8 (1993) 256-264
54. Pietak A.M., Reid J.W., Stott M.J., and Sayer M. Silicon substitution in the calcium phosphate bioceramics. Biomaterials 28 (2007) 4023-4032
55. Trump B.F., and Berezesky I.K. Calcium-mediated cell injury and cell death. FASEB J 9 (1995) 219-228