Biochemical characterization and evaluation of a Brugia malayi small heat shock protein as a vaccine against lymphatic filariasis

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Dakshinamoorthy, Gajalakshmi ^a   Samykutty, Abhilash Kumble ^a,b   Munirathinam, Gnanasekar ^a   Shinde, Gangadhar Bhaurao ^c   Nutman, Thomas ^d   Reddy, Maryada Venkatarami ^b   Kalyanasundaram, Ramaswamy ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

^b MAHATMA GANDHI INSTITUTE OF MEDICAL SCIENCES   (India)

^c RTM NAGPUR UNIVERSITY   (India)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BMHSP12.6 PROTEIN; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G3 ANTIBODY; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR; SMALL HEAT SHOCK PROTEIN; UNCLASSIFIED DRUG; CYTOKINE; DNA VACCINE; HELMINTH ANTIBODY; IMMUNOGLOBULIN G; PARASITE ANTIGEN; PEPTIDE FRAGMENT; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY DETECTION; ARTICLE; B LYMPHOCYTE; BINDING SITE; BLOOD SAMPLING; BRUGIA MALAYI; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG SCREENING; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNE EVASION; IMMUNITY; IMMUNOREGULATION; IMMUNOSUPPRESSIVE TREATMENT; IN VITRO STUDY; LYMPHATIC FILARIASIS; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; RECEPTOR BINDING; T LYMPHOCYTE; VACCINATION; ANIMAL; ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; BAGG ALBINO MOUSE; BLOOD; CELL PROLIFERATION; CYTOLOGY; EVALUATION; GENETICS; IMMUNOLOGY; MAST CELL; METABOLISM; MOLECULAR GENETICS; SPLEEN;

BRUGIA MALAYI; NEMATODA;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, HELMINTH; ANTIBODY-DEPENDENT CELL CYTOTOXICITY; ANTIGENS, HELMINTH; BRUGIA MALAYI; CELL PROLIFERATION; CYTOKINES; ELEPHANTIASIS, FILARIAL; HEAT-SHOCK PROTEINS, SMALL; HUMANS; IMMUNOGLOBULIN G; INTERLEUKIN-10; MALE; MAST CELLS; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; RECEPTORS, INTERLEUKIN-10; RECOMBINANT PROTEINS; SPLEEN; VACCINATION; VACCINES, DNA;

EID: 84859350058     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0034077     Document Type: Article

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