Recent developments in acute liver failure

Best Practice and Research: Clinical Gastroenterology

Volumn 26, Issue 1, 2012, Pages 3-16

  Lee, William M ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Acetaminophen toxicity; Acute liver injury; Coagulopathy; Encephalopathy; Hepatic necrosis

Indexed keywords

ACETYLCYSTEINE; AMINOTRANSFERASE; BILIRUBIN; FRESH FROZEN PLASMA; HYDROCODONE; ISONIAZID; PARACETAMOL; PENICILLIN G; PRESCRIPTION DRUG; RECOMBINANT BLOOD CLOTTING FACTOR 7A; SILIBININ;

ACUTE LIVER FAILURE; AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; AUTOIMMUNE HEPATITIS; BLEEDING; BLOOD CLOTTING DISORDER; BRAIN DISEASE; BRAIN EDEMA; BUDD CHIARI SYNDROME; CHRONIC HEPATITIS; CLINICAL TRIAL (TOPIC); COMA; CONFUSION; CRYOPRECIPITATE; DISEASE COURSE; DRUG INTOXICATION; DRUG OVERDOSE; DRUG TOLERANCE; FLUID RESUSCITATION; FUNGEMIA; HEPATITIS A; HEPATITIS B; HERPES VIRUS; HUMAN; HUMAN PARVOVIRUS B19; IMMUNOSUPPRESSIVE TREATMENT; INTENSIVE CARE; INTERNATIONAL NORMALIZED RATIO; INTRACRANIAL PRESSURE; INTRACRANIAL PRESSURE MONITORING; KUPFFER CELL; LIVER CELL DAMAGE; LIVER CIRRHOSIS; LIVER INJURY; LIVER TOXICITY; LIVER TRANSPLANTATION; MORTALITY; MULTIPLE ORGAN FAILURE; MUSHROOM POISONING; OVERALL SURVIVAL; PROGNOSIS; PROTHROMBIN TIME; PULMONARY ARTERY CATHETER; RETROSPECTIVE STUDY; SENSORY SYSTEM; SUICIDE ATTEMPT; UNITED KINGDOM; VASOCONSTRICTION; VIRUS HEPATITIS; VIRUS REACTIVATION;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; CRITICAL CARE; HUMANS; INTENSIVE CARE; LIVER FAILURE, ACUTE; LIVER TRANSPLANTATION; PROGNOSIS; RARE DISEASES;

EID: 84859319115     PISSN: 15216918     EISSN: 15321916     Source Type: Journal    
DOI: 10.1016/j.bpg.2012.01.014     Document Type: Article

References (59)

1. C. Trey, and C.S. Davidson The management of fulminant hepatic failure H. Popper, F. Schaffner, Progress in liver diseases 1970 Grune & Stratton New York 282 298
2. W.M. Lee, R.H. Squires Jr., S.L. Nyberg, E. Doo, and J.H. Hoofnagle Acute liver failure: summary of a workshop Hepatology 47 2008 1401 1415 (Pubitemid 351547926)
3. W. Bernal, G. Auzinger, A. Dhawan, and J. Wendon Acute liver failure Lancet 376 2010 190 201
4. G.A. Ostapowicz, R.J. Fontana, F.V. Schiodt, A. Larson, T.J. Davern, and S.H. Han Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States Ann Intern Med 137 2002 947 954 (Pubitemid 35440240)
5. R.T. Stravitz, A.H. Kramer, T. Davern, A.O.S. Shaikh, S.H. Caldwell, and R.L. Mehta Intensive care of patients with acute liver failure: recommendations of the Acute Liver Failure Study Group Crit Care Med 35 2007 2498 2508 (Pubitemid 351339009)
6. R.T. Stravitz, and D.J. Kramer Management of acute liver failure Nat Rev Gastroenterol Hepatol 6 2009 542 553
7. W.M. Lee, and F.V. Schiødt Fulminant hepatic failure E.R. Schiff, M.F. Sorrell, W.C. Maddrey, Schiff's diseases of the liver 8th ed 1999 Lippincott-Raven Publishers Philadelphia 879 895
8. F.V. Schiødt, E. Atillasoy, O. Shakil, and W.M. Lee Etiology and outcome for 295 patients with acute liver failure in the United States Liver Transpl Surg 5 1999 29 34 (Pubitemid 29037351)
9. W.M. Lee, and E. Seremba Etiologies of acute liver failure Curr Opin Crit Care 14 2008 198 201 (Pubitemid 351498786)
10. S.K. Acharya, S. Dasarathy, T.L. Kumer, S. Sushma, K.S.U. Prasanna, and A. Tandon Fulminant hepatitis in a tropical population: clinical course, cause, and early predictors of outcome Hepatology 23 1996 1448 1455 (Pubitemid 26181228)
11. H.J. Zimmerman, and W.C. Maddrey Acetaminophen (paracetamol) hepatotoxicity with regular intake of alcohol: analysis of instances of therapeutic misadventure Hepatology 22 1995 767 773
12. A.O. Shakil, D. Kramer, G.V. Mazariegos, J.J. Fung, and J. Rakela Acute liver failure: clinical features, outcome analysis, and applicability of prognostic criteria Liver Transpl 6 2000 163 169 (Pubitemid 30173994)
13. F.V. Schiodt, F.A. Rochling, D.L. Casey, and W.M. Lee Acetaminophen toxicity in an urban county hospital N Engl J Med 337 1997 1112 1117 (Pubitemid 27444101)
14. A.M. Larson, R.J. Fontana, T.J. Davern, J. Polson, E.K. Lalani, L.S. Hynan the ALFSG Acetaminophen-induced acute liver failure: results of a United States multicenter, prospective study Hepatology 42 2005 1367 1372
15. R.M. Shayiq, D.W. Roberts, K. Rothstein, J.E. Snawder, W. Benson, and X. Ma Repeat exposure to incremental doses of acetaminophen provides protection against acetaminophen-induced lethality in mice: an explanation for high acetaminophen dosage in humans without hepatic injury Hepatology 29 1999 451 463 (Pubitemid 29088449)
16. A.M. Larson Acetaminophen hepatotoxicity Clin Liver Dis 11 2007 525 548 (Pubitemid 47302345)
17. T.J. Davern II, L.P. James, J.A. Hinson, J. Polson, A.M. Larson, and R.J. Fontana Measurement of serum acetaminophen-protein adducts in patients with acute liver failure Gastroenterology 130 2006 687 694 (Pubitemid 43374519)
18. L.P. James, E.M. Alonso, L.S. Hynan, J.A. Hinson, T.J. Davern, and W.M. Lee Detection of acetaminophen-protein adducts in children with acute liver failure of indeterminate cause Pediatrics 118 2006 e676 e681
19. N. Khandelwal, L.P. James, C. Sanders, A.M. Larson, W.M. Lee Acute Liver Failure Study Group Unrecognized acetaminophen toxicity as a cause of indeterminate acute liver failure Hepatology 53 2011 567 576
20. P.B. Watkins, N. Kaplowitz, J.T. Slattery, C.R. Colonese, S.V. Colucci, and P.W. Stewart Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen per day JAMA 296 2006 87 93
21. FDA Drug Safety Communication. http://www.fda.gov/Drugs/DrugSafety/ ucm239821.htm [accessed 21.08.11].
22. http://www.nytimes.com/2011/01/14/health/policy/14fda.html?scp=1&sq= tylenol%20package&st=cse [accessed 21.08.11].
23. N. Chalasani, R.J. Fontana, H.L. Bonkovsky, P.B. Watkins, T. Davern, and J. Serrano Causes, clinical features, and outcomes from a prospective study of drug-induced liver injury in the United States Gastroenterology 135 2008 1924 1934
24. A. Reuben, D.G. Koch, W.M. Lee the Acute Liver Failure Study Group Drug induced acute liver failure: results of a United States multicenter, prospective study Hepatology 52 2010 2065 2078
25. D.Y. Dao, L.S. Hynan, H.J. Yuan, C. Sanders, J. Balko, and N. Attar Two distinct types of hepatitis B-related acute liver failure are separable by quantitative anti-HBc IgM and HBV DNA levels Hepatology 2011 Epub ahead of print, October 10
26. R.T. Stravitz, J.H. Lefkowitch, R.J. Fontana, M.E. Gershwin, P.S. Leung, R.K. Sterling the ALFSG Autoimmune acute liver failure: proposed clinical and histological criteria Hepatology 53 2011 517 526
27. J.D. Korman, I. Volenberg, J. Balko, J. Webster, F.V. Schiodt, and R.H. Squires Jr. Screening for Wilson disease in acute liver failure: a comparison of currently available diagnostic tests Hepatology 48 2008 1167 1174
28. D. Rowbotham, J. Wendon, and R. Williams Acute liver failure secondary to hepatic infiltration: a single centre experience of 18 cases Gut 42 1998 576 580 (Pubitemid 28186579)
29. W.M. Lee, K.E. Brown, N.S. Young, G.J. Dawson, G.G. Schlauder, R.A. Gutierrez the Acute Liver Failure Study Group Brief report: no evidence for hepatitis E or parvovirus B19 infection in patients with acute liver failure Dig Dis Sci 51 2006 1712 1715
30. J. Levitsky, A. Thadareddy, F.D. Lakeman, R.J. Whitley, J.P. Luby, and W.M. Lee Detection and diagnosis of herpes simplex virus infection in adults with acute liver failure Liver Transpl 14 2008 1498 1504
31. J. Polson, and W.M. Lee AASLD position paper: acute liver failure Hepatology 41 2005 1179 1197 (Pubitemid 40593928)
32. W.M. Lee, L.S. Hynan, L. Rossaro, R.J. Fontana, R.T. Stravitz, A.M. Larson the ALFSG Intravenous N-acetylcysteine improves transplant-free survival in early stage non-acetaminophen acute liver failure Gastroenterology 137 2009 856 864
33. M. Oketani, A. Ido, and H. Tsubouchi Changing etiologies and outcomes of acute liver failure: a perspective from Japan J Gastroenterol Hepatol 26 Suppl. 1 2011 65 71
34. M.F. Sorrell, E.A. Belongia, J. Costa, I.F. Gareen, J.L. Grem, and J.M. Inadomi National Institutes of Health Consensus Development Conference Statement: management of hepatitis B Ann Intern Med 150 2009 104 110
35. A.T. Blei Pathogenesis of brain edema in fulminant hepatic failure Prog Liver Dis 13 1995 311 330
36. R. Jalan Pathophysiological basis of therapy of raised intracranial pressure in acute liver failure Neurochem Int 47 1-2 2005 Jul 78 83 (Pubitemid 40848696)
37. F.S. Larsen, and J. Wendon Prevention and management of brain edema in patients with acute liver failure Liver Transpl 14 Suppl. 2 2008 Oct S90 S96
38. J.O. Clemmesen, F.S. Larsen, J. Kondrup, B.A. Hansen, and P. Ott Cerebral herniation in patients with acute liver failure is correlated with arterial ammonia concentration Hepatology 29 1999 648 653 (Pubitemid 29109575)
39. J. Vaquero, R.J. Fontana, A.M. Larson, N.M. Bass, T.J. Davern, and A.O. Shakil Complications and use of intracranial pressure monitoring in patients with acute liver failure and severe encephalopathy Liver Transpl 11 2005 1581 1589 (Pubitemid 43072637)
40. N.K. Parekh, L.S. Hynan, J. De Lemos, W.M. Lee the ALF Study Group Elevated troponin I levels in acute liver failure: is myocardial injury an integral part of the acute liver failure? Hepatology 45 2007 1489 1495 (Pubitemid 46918333)
41. R.T. Stravitz, T. Lisman, V.A. Luketic, R.K. Sterling, P. Puri, and M. Fuchs Minimal effects of acute liver injury/acute liver failure on hemostasis as assessed by thromboelastography J Hepatol 2011 May 19 [Epub ahead of print]
42. F.V. Schiodt, J. Balko, M.C. Schilsky, E.H. Harrison, A. Thornton, W.M. Lee the ALFSG Thrombopoietin in acute liver failure Hepatology 37 2003 558 561 (Pubitemid 36258777)
43. J. Vaquero, J. Polson, C. Chung, I. Helenowski, F.V. Schiodt, J. Reisch the Acute Liver Failure Study Group Infection and the progression to deep hepatic encephalopathy in early fulminant hepatic failure Gastroenterology 125 2003 755 764 (Pubitemid 37070693)
44. N. Rolando, J.J. Wade, A. Stangou, A.E. Gimson, J. Wendon, and J. Philpott-Howard Prospective study comparing the efficacy of prophylactic parenteral antimicrobials, with or without enteral decontamination, in patients with acute liver failure Liver Transpl Surg 2 1996 8 13 (Pubitemid 26045199)
45. J. O'Grady, G. Alexander, K. Hayllar, and R. Williams Early indicators of prognosis in fulminant hepatic failure Gastroenterology 97 1989 439 445 (Pubitemid 19192181)
46. M.B. Zaman, E. Hoti, A. Qasim, D. Maguire, and P.A. McCormick MELD score as a prognostic model for listing acute liver failure patients for liver transplantation Transpl Proc 38 2006 2097 2098 (Pubitemid 46068453)
47. A. Katoonizadeh, J. Decaestecker, A. Wilmer, R. Aerts, C. Verslype, and W. Vansteenbergen MELD score to predict outcome in adult patients with non-acetaminophen-induced acute liver failure Liver Int 27 2007 329 334 (Pubitemid 46416622)
48. D.S. Shouval, E. Mor, Y. Avitzur, R. Shamir, N. Bar-Nathan, and R. Steinberg Living-related donor liver transplantation for children with fulminant hepatic failure in Israel J Pediatr Gastroenterol Nutr 48 2009 451 455
49. A.J. Hanje, A. Michaels, and W.M. Lee Is N-acetylcysteine effective in all non-acetaminophen acute liver failure? Donald M. Jensen, Controversies in hepatology 2011 Slack Incorporated Philadelphia
50. S.K. Acharya, V. Bhatia, and V. Sreenivas Efficacy of L-ornithine L-aspartate in acute liver failure: a double-blind, randomized, placebo-controlled study Gastroenterology 136 2009 2159 2168
51. W.M. Lee, and R.V. Jalan Treatment of hyperammonemia in liver failure: a tale of two enzymes Gastroenterology 136 2009 2048 2051
52. N.A. Davies, G. Wright, L.M. Ytrebo, V. Stadlbauer, O.M. Fuskevag, and C. Zwingmann L-ornithine and phenylacetate synergistically produce sustained reduction in ammonia and brain water in cirrhotic rats Hepatology 50 2009 155 164
53. L.M. Ytrebo, R.G. Kristiansen, H. Maehre, O.M. Fuskevag, T. Kalstad, and A. Revhaug L-ornithine phenylacetate attenuates increased arterial and extracellular brain ammonia and prevents intracranial hypertension in pigs with acute liver failure Hepatology 50 2009 165 174
54. A. Demetriou, R.S. Brown, R.W. Busuttil, J. Fair, and B.M. McGuire Prospective, randomized, multicenter, controlled trial of a bioartificial liver in treating acute liver failure Ann Surg 239 2000 660 670
55. R. Jalan, S. Sen, and R. Williams Prospects for extracorporeal liver support Gut 53 2004 890 898 (Pubitemid 38662142)
56. J. Liu, L.L. Khaergard, B. Asl-Nielsen, and C. Gluud Artificial and bioartificial support systems for liver failure: a Cochrane Hepato-Biliary Group Protocol Liver 22 2002 433
57. R.S. Chari, B.H. Collins, J.C. Magee, J.M. DiMaio, A.D. Kirk, and R.C. Harland Brief report: treatment of hepatic failure with ex vivo pig liver perfusion followed by liver transplantation N Engl J Med 331 1994 234 237 (Pubitemid 24226681)
58. S.P. Horslen, J.M. Hammel, L.W. Fristoe, J.A. Kangas, D.S. Collier, and D.L. Sudan Extracorporeal liver perfusion using human and pig livers for acute liver failure Transplantation 70 2000 1472 1478
59. K. Fukumitsu, H. Yagi, and A. Soto-Gutierrez Bioengineering in organ transplantation: targeting the liver Transpl Proc 43 2011 2137 2138