Elevated troponin I levels in acute liver failure: Is myocardial injury an integral part of acute liver failure?

Hepatology

Volumn 45, Issue 6, 2007, Pages 1489-1495

  Parekh, Nimisha K ^a   Hynan, Linda S ^a,b   De Lemos, James ^a   Lee, William M ^a   Polson, Julie ^b   Pezzia, Carla ^b   Lalani, Ezmina ^b   Reisch, Joan S ^b   Larson, Anne M ^c   Do, Hao ^c   Crippin, Jeffrey S ^d   Gerstle, Laura ^d   Davern, Timothy J ^e   Partovi, Katherine ^e   Emre, Sukru ^f   McCashland, Timothy M ^g   Bernard, Tamara ^g   Hay, J Eileen ^h   Groettum, Cindy ^h   Murray, Natalie ⁱ   Coultrup, Sonnya ⁱ   Shakil, A Obaid ^j   Morton, Diane ^j   Blei, Andres T ^k   Gottstein, Jeanne ^k   Zaman, Atif ^l   Schwartz, Jonathan ^l   Ingram, Ken ^l   Han, Steven ^m   Peacock, Val ^m   Fontana, Robert J ⁿ   Welch, Suzanne ⁿ   McGuire, Brendan ^o   Avant, Linda ^o   Chung, Raymond ^p   Casson, Deborah ^p   Brown Jr , Robert ^q   Schilsky, Michael ^q   Senkbeil, Laren ^q   Harrison, M Edwyn ^r   Rush, Rebecca ^r   Reuben, Adrian ^s   Huntley, Nancy ^s   Munoz, Santiago ^t   Misra, Chandra ^t   Stravitz, Todd ^u   Salvatori, Jennifer ^u   Rossaro, Lorenzo ^v   Prosser, Colette ^v   Satyanarayana, Raj ^w   Taylor, Wendy ^w   Reddy, Raj ^x   Campbell, Mical ^x   Hassenein, Tarek ^y   Barakat, Fatma ^y   Smith, Alistair ^z   more..

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f MOUNT SINAI MEDICAL CENTER   (United States)

^g UNIVERSITY OF NEBRASKA AT OMAHA   (United States)

^h MAYO CLINIC   (United States)

ⁱ BAYLOR UNIVERSITY MEDICAL CENTER   (United States)

^j UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^k NORTHWESTERN UNIVERSITY   (United States)

^l OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^m UNIVERSITY OF CALIFORNIA   (United States)

ⁿ UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^o UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^p MASSACHUSETTS GENERAL HOSPITAL   (United States)

^q New York Presbyterian Hospital Columbia University Medical Center   (United States)

^r MAYO CLINIC   (United States)

^s MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^t ALBERT EINSTEIN MEDICAL CENTER   (United States)

^u VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^v UNIVERSITY OF CALIFORNIA   (United States)

^w MAYO CLINIC   (United States)

^x UNIVERSITY OF PENNSYLVANIA   (United States)

^y UNIVERSITY OF CALIFORNIA   (United States)

^z DUKE UNIVERSITY   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

PARACETAMOL; TROPONIN I;

ADOLESCENT; ADULT; AGED; ARTICLE; CONTROLLED STUDY; FEMALE; HEART MUSCLE INJURY; HUMAN; LIVER FAILURE; LIVER INJURY; MAJOR CLINICAL STUDY; MALE; MORBIDITY; PRIORITY JOURNAL; PROGNOSIS; VIRUS HEPATITIS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; APACHE; BIOLOGICAL MARKERS; FEMALE; HEART DISEASES; HUMANS; LIVER FAILURE, ACUTE; MALE; MIDDLE AGED; MORBIDITY; MYOCARDIUM; PREVALENCE; REGISTRIES; SENSITIVITY AND SPECIFICITY; TROPONIN I;

EID: 34250353524     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.21640     Document Type: Article

References (20)

1. Ostapowicz G, Fontana RJ, Schiodt FV, Larson A, Davern TJ, Han SH, et al. Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States. Ann Intern Med 2002;137:947-954.
2. Larson AM, Fontana RJ, Davern TJ, Polson J, Lalani EK, Hynan LS, et al. Acetaminophen-induced acute liver failure: Results of a United States multicenter, prospective study. HEPATOLOGY 2005;42:1367-1372.
3. Pimstone BL, Uys CJ. Liver necrosis and myocardiopathy following paracetamol overdosage. S Afr Med J 1968;42:259-262.
4. Sanerkin NG. Acute myocardial necrosis in paracetamol poisoning. Br Med J 1971;3:478.
5. Wakeel RA, Davies HT, Williams JD. Toxic myocarditis in paracetamol poisoning. Br Med J 1987;295:1097.
6. Mann JM, Peirre-Louis M, Kragel PJ, Kragel AH, Roberts WC. Cardiac consequences of massive acetaminophen overdose. Am J Cardiol 1989;63: 1018-1021.
7. Weston MJ, Talbot IC, Howorth PJN, Mant AK, Capildeo R, Williams R. Frequency of arrhythmias and other cardiac abnormalities in fulminant hepatic failure. Br Heart J 1976;38:1179-1188.
8. Amour A, Slater SD. Paracetamol cardiotoxiciry. Postgrad Med J 1993;69: 52-54.
9. Jones AL. Unusual complications of paracetamol poisoning. Q J Med 1997;90:161-168.
10. Fortunato A, Giavarina D. Decision limit for troponin I on ADVIA: Centaur and evaluation of the analytical precision at low concentration. Clin Lab 2003;49:251-253.
11. Cardinale D, Sandri MT, Colombo A, Colombo N, Boeri M, Lamantia G, et al. Prognostic value of troponin I in cardiac risk stratification of cancer patients undergoing high-dose chemotherapy. Circulation 2004;109: 2749-2754.
12. Hamm CW. Cardiac troponin elevations in patients without acute coronary syndrome. Circulation 2002;106:2871-2872.
13. Wu T, Yuan A, Chen CY, Chen WJ, Luh KT, Kuo SC, et al. Cardiac troponin I levels are a risk factor for mortality and multiple organ failure in noncardiac critically ill patients and have an additive effect to the APACHE II score in outcome prediction. Shock 2004;22:95-101.
14. Pham MX, Whooley MA, Evans GT Ji, Liu C, Emadi H, Tong W, et al. Prognostic value of low-level of cardiac troponin-I elevations in patients without definite acute coronary syndromes. Am Heart J 2004;148:776-782.
15. Apple FS, Murakami MM, Pearce LA, Herzog CA. Predictive value of cardiac troponin I and T and subsequent death in end stage renal disease. Circulation 2002;106:2941-2945.
16. Apple FS, Murakami MM, Pearce LA, Herzog CA. Multi-biomarker risk stratification of N-terminal pro-B-type natriuretic peptide, high-sensitivity C-reactive protein, and cardiac troponin T and I in end-stage renal disease for all-cause death. Clin Chem 2004;50:2279-2285.
17. Freda BJ, Tang WH, Van Lente F, Peacock WF, Francis GS. Cardiac troponins in renal insufficiency: review and clinical implications. J Am Coll Cardiol 2002;40:2065-2071.
18. DeZoysa JR. Cardiac troponins and renal disease. Nephrology 2004;9:83-88.
19. Ooi DS, Isotalo PA, Veinot JP. Correlation of antemorrem serum creatine kinase, creatine kinase-MB, troponin I, and troponin T with cardiac pathology. Clin Chem 2000;46:338-344.
20. Ammann P, Maggiorini M, Bertel O, Haenseler E, Joller-Jemelka HI, Oechslin E, et al. Troponin as a risk factor for mortality in critically ill patients without acute coronary syndromes. J Amer Coll Cardiol 2003;41: 2004-2009.