Optimization of 100 μm alginate-poly-l-lysine-alginate capsules for intravitreous administration

Journal of Controlled Release

Volumn 158, Issue 3, 2012, Pages 443-450

  Santos, E ^a,b   Orive, G ^a,b   Calvo, A ^c   Catena, R ^c   Fernandez Robredo P ^d   Layana, A García ^d   Hernandez R M ^a,b   Pedraz, J L ^a,b  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^b BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

^c UNIVERSITY OF NAVARRA   (Spain)

^d UNIVERSITY CLINIC OF NAVARRA   (Spain)

Author keywords

APA; Central Nervous Disease; Flow focusing; Intravitreous; Microcapsule; Reduced size

Indexed keywords

APA; FLOW FOCUSING; INTRAVITREOUS; MICROCAPSULES; REDUCED SIZE;

ALGINATE; BIOCOMPATIBILITY; CELL PROLIFERATION; GENES; GENETIC ENGINEERING;

ENCAPSULATION;

ALGINATE POLYLYSINE ALGINATE; GREEN FLUORESCENT PROTEIN; LUCIFERASE; THYMIDINE KINASE; VASCULOTROPIN RECEPTOR 2;

ANIMAL CELL; ARTICLE; CELL ENCAPSULATION; CELL METABOLISM; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DISPERSION; DRUG DELIVERY SYSTEM; GENE EXPRESSION; GENETIC ENGINEERING; MICROCAPSULE; MICROENCAPSULATION; MOUSE; MYOBLAST; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN SECRETION; RAT; REPORTER GENE;

ALGINATES; ANIMALS; CAPSULES; CELL LINE; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; INTRAVITREAL INJECTIONS; LUCIFERASES; MICE; MICE, INBRED C3H; POLYLYSINE; RATS; RATS, WISTAR; THYMIDINE KINASE; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 84859265342     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.09.079     Document Type: Article

References (40)

1. P. Aebischer, and J. Ridet Recombinant proteins for neurodegenerative diseases: the delivery issue Trends Neurosci. 24 2001 533 540 (Pubitemid 32744708)
2. M.S. Shoichet, and S.R. Winn Cell delivery to the central nervous system Adv. Drug Deliv. Rev. 42 2000 81 102 (Pubitemid 30609636)
3. G. Orive, R.M. Hernández, A.R. Gascón, R. Calafiore, T.M. Chang, P. De Vos, G. Hortelano, D. Hunkeler, I. Lacík, A.M. Shapiro, and J.L. Pedraz Cell encapsulation: promise and progress Nat. Med. 9 2003 104 107 (Pubitemid 36098269)
4. G.J. Lim, S. Zare, M. Van Dyke, and A. Atala Cell microencapsulation Adv. Exp. Med. Biol. 670 2010 126 136
5. A. Murua, A. Portero, G. Orive, R.M. Hernández, M. de Castro, and J.L. Pedraz Cell microencapsulation technology: towards clinical application J. Control. Release 132 2008 76 83
6. B. Salmons, M. Löhr, and W.H. Günzburg Treatment of inoperable pancreatic carcinoma using a cell-based local chemotherapy: results of a phase I/II clinical trial J. Gastroenterol. 38 Suppl 15 2003 78 84 (Pubitemid 36442892)
7. J. Bloch, A.C. Bachoud-Lévi, N. Déglon, J.P. Lefaucheur, L. Winkel, S. Palfi, J.P. Nguyen, C. Bourdet, V. Gaura, P. Remy, P. Brugières, M.F. Boisse, S. Baudic, P. Cesaro, P. Hantraye, P. Aebischer, and M. Peschanski Neuroprotective gene therapy for Huntington's disease, using polymer-encapsulated cells engineered to secrete human ciliary neurotrophic factor: results of a phase I study Hum. Gene Ther. 15 2004 968 975 (Pubitemid 39372573)
8. R. Calafiore, G. Basta, G. Luca, A. Lemmi, L. Racanicchi, F. Mancuso, M.P. Montanucci, and P. Brunetti Standard technical procedures for microencapsulation of human islets for graft into nonimmunosuppressed patients with type 1 diabetes mellitus Transplant. Proc. 38 2006 1156 1157 (Pubitemid 43815904)
9. P.A. Sieving, R.C. Caruso, W. Tao, H.R. Coleman, D.J. Thompson, K.R. Fullmer, and R.A. Bush Ciliary neurotrophic factor (CNTF) for human retinal degeneration: phase I trial of CNTF delivered by encapsulated cell intraocular implants Proc. Natl. Acad. Sci. U. S. A. 103 2006 3896 3901 (Pubitemid 43376652)
10. C. Spuch, D. Antequera, A. Portero, G. Orive, R.M. Hernández, J.A. Molina, F. Bermejo-Pareja, J.L. Pedraz, and E. Carro The effect of encapsulated VEGF-secreting cells on brain amyloid load and behavioral impairment in a mouse model of Alzheimer's disease Biomaterials 31 2010 5608 5618
11. S. Sugiura, T. Oda, Y. Aoyagi, R. Matsuo, T. Enomoto, K. Matsumoto, T. Nakamura, M. Satake, A. Ochiai, N. Ohkohchi, and M. Nakajima Microfabricated airflow nozzle for microencapsulation of living cells into 150 micrometer microcapsules Biomed. Microdevices 9 2007 91 99 (Pubitemid 46050133)
12. R. Robitaille, J.F. Pariseau, F.A. Leblond, M. Lamoureux, Y. Lepage, and J.P. Hallé Studies on small (< 350 microm) alginate-poly-l-lysine microcapsules, III. Biocompatibility of smaller versus standard microcapsules J. Biomed. Mater. Res. 44 1999 116 120 (Pubitemid 28544092)
13. J.T. Wilson, and E.L. Chaikof Challenges and emerging technologies in the immunoisolation of cells and tissues Adv. Drug Deliv. Rev. 60 2008 124 145 (Pubitemid 350245691)
14. S. Sakai, and K. Kawakami Development of subsieve-size capsules and application to cell therapy Adv. Exp. Med. Biol. 670 2010 22 30
15. J. Xie, and C.H. Wang Electrospray in the dripping mode for cell microencapsulation J. Colloid Interface Sci. 312 2007 247 255 (Pubitemid 46935782)
16. V.T. Tran, J.P. Benoît, and M.C. Venier-Julienne Why and how to prepare biodegradable, monodispersed, polymeric microparticles in the field of pharmacy? Int. J. Pharm. 407 2011 1 11
17. C. Schwinger, A. Klemenz, K. Busse, and J. Kressler Encapsulation of living cells with polymeric systems Macromol. Symp. 210 2004 493 499
18. J.M. Rabanel, X. Banquy, H. Zouaoui, M. Mokhtar, and P. Hildgen Progress technology in microencapsulation methods for cell therapy Biotechnol. Prog. 25 2009 946 963
19. L.S. Kontturi, M. Yliperttula, P. Toivanen, A. Määttä, M. Määttä, and A. Urtti. A laboratory-scale device for the straightforward production of uniform, small sized cell microcapsules with long-term cell viability J. Control. Release 2011 10.1016/j.jconrel.2011.03.005
20. C.J. Ross, and P.L. Chang Development of small alginate microcapsules for recombinant gene product delivery to the rodent brain J. Biomater. Sci. Polym. Ed. 13 2002 953 962 (Pubitemid 35345396)
21. J. Hong, A.J. deMello, and S.N. Jayasinghe Bio-electrospraying and droplet-based microfluidics: control of cell numbers within living residues Biomed. Mater. 5 2010 21001
22. A.M. Gañán-Calvo, and J.M. Gordillo Perfectly monodisperse microbubbling by capillary flow focusing Phys. Rev. Lett. 87 2001 274501
23. L. Martín-Banderas, M. Flores-Mosquera, P. Riesco-Chueca, A. Rodríguez-Gil, A. Cebolla, S. Chávez, and A.M. Gañán-Calvo Flow Focusing: a versatile technology to produce size-controlled and specific-morphology microparticles Small 1 2005 688 692 (Pubitemid 43951724)
24. J.Z. Nowak Age-related macular degeneration (AMD): pathogenesis and therapy Pharmacol. Rep. 58 2006 353 363 (Pubitemid 44111070)
25. N. Kwak, N. Okamoto, J.M. Wood, and P.A. Campochiaro VEGF is major stimulator in model of choroidal neovascularization Invest. Ophthalmol. Vis. Sci. 41 2000 3158 3164
26. N.M. Bressler Early detection and treatment of neovascular age-related macular degeneration J. Am. Board Fam. Pract. 15 2002 142 152 (Pubitemid 34415866)
27. C.A. Augood, J.R. Vingerling, P.T. de Jong, U. Chakravarthy, J. Seland, G. Soubrane, L. Tomazzoli, F. Topouzis, G. Bentham, M. Rahu, J. Vioque, I.S. Young, and A.E. Fletcher Prevalence of age-related maculopathy in older Europeans: the European Eye Study (EUREYE) Arch. Ophthalmol. 124 2006 529 535
28. G.C. Brown, M.M. Brown, S. Sharma, J.D. Stein, Z. Roth, J. Campanella, and G.R. Beauchamp The burden of age-related macular degeneration: a value-based medicine analysis Trans. Am. Ophthalmol. Soc. 103 2005 173 184
29. V. Ponomarev, M. Doubrovin, I. Serganova, J. Vider, A. Shavrin, T. Beresten, A. Ivanova, L. Ageyeva, V. Tourkova, J. Balatoni, W. Bornmann, R. Blasberg, and J. Gelovani Tjuvajev A novel triple-modality reporter gene for whole-body fluorescent, bioluminescent, and nuclear noninvasive imaging Eur. J. Nucl. Med. Mol. I. 31 2004 740 751 (Pubitemid 38647915)
30. R. Catena, E. Santos, G. Orive, R.M. Hernández, J.L. Pedraz, and A. Calvo Improvement of the monitoring and biosafety of encapsulated cells using the SFGNESTGL triple reporter system J. Control. Release 146 2010 93 98
31. F. Lim, and A.M. Sun Microencapsulated islets as bioartificial endocrine pancreas Science 210 1980 908 910 (Pubitemid 11169847)
32. A.M. Gañán-Calvo, and J.M. Montanero Revision of capillary cone-jet physics: electrospray and flow focusing Phys. Rev. E Stat. Nonlin. Soft Matter Phys. 79 6 Pt 2 2009 066305
33. J.M. Montanero, N. Rebollo-Muñoz, M.A. Herrada, and A.M. Gañán-Calvo. Global stability of the focusing effect of fluid jet flows Phys. Rev. E. 83 3 Pt2 2011 036309
34. B.L. Strand, O. Gåserød, B. Kulseng, T. Espevik, and G. Skjåk-Baek Alginate-polylysine-alginate microcapsules: effect of size reduction on capsule properties J. Microencapsul. 19 2002 615 630 (Pubitemid 35230093)
35. S. Ponce, G. Orive, R. Hernández, A.R. Gascón, J.L. Pedraz, B.J. de Haan, M.M. Faas, H.J. Mathieu, and P. de Vos Chemistry and the biological response against immunoisolating alginate-polycation capsules of different composition Biomaterials 27 2006 4831 4839 (Pubitemid 43884839)
36. G. Orive, S.K. Tam, J.L. Pedraz, and J.P. Hallé Biocompatibility of alginate-poly-l-lysine microcapsules for cell therapy Biomaterials 27 2006 3691 3700 (Pubitemid 43670522)
37. E. Hill, T. Boontheekul, and D.J. Mooney Designing scaffolds to enhance transplanted myoblast survival and migration Tissue Eng. 12 2006 1295 1304 (Pubitemid 44024499)
38. A. Leung, L.K. Nielsen, M. Trau, and N.E. Timmins Tissue transplantation by stealth - coherent alginate microcapsules for immunoisolation Biochem. Eng. J. 48 2010 337 347
39. G. Orive, R.M. Hernández, A.R. Gascón, M. Igartua, and J.L. Pedraz Survival of different cell lines in alginate-agarose microcapsules Eur. J. Pharm. Sci. 18 2003 23 30 (Pubitemid 36124011)
40. J.Y. Niederkorn See no evil, hear no evil, do no evil: the lessons of immune privilege Nat. Immunol. 7 2006 354 359