Bio-electrospraying and droplet-based microfluidics: Control of cell numbers within living residues

Biomedical Materials

Volumn 5, Issue 2, 2010, Pages

  Hong, Jongin ^a   Demello, Andrew J ^a   Jayasinghe, Suwan N ^b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DROP FORMATION; ENCAPSULATION; MICROFLUIDICS; STEM CELLS; TISSUE ENGINEERING;

BIOLOGY AND MEDICINE; CAENORHABDITIS ELEGANS; CELL ENCAPSULATIONS; CELL NUMBER; DANIO RERIO; DROPLET-BASED MICROFLUIDICS; ELECTROSPRAYING; HIGH EFFICIENCY; LIVE CELL; THREE-DIMENSIONAL CULTURE; TYPE I DIABETES; XENOPUS;

CELL CULTURE;

ARTICLE; CAENORHABDITIS ELEGANS; CELL COUNT; CELL IMMORTALIZATION; CONTROLLED STUDY; DROSOPHILA; ELECTROSPRAY; ENCAPSULATION; MICROFLUIDICS; NONHUMAN; REGENERATIVE MEDICINE; STEM CELL; TISSUE ENGINEERING; XENOPUS; ZEBRA FISH; BIOREACTOR; CELL SEPARATION; CULTURE TECHNIQUE; ELECTRONICS; EQUIPMENT; EQUIPMENT DESIGN; EVALUATION; FLOW CYTOMETRY; HUMAN; INSTRUMENTATION; LEUKEMIA CELL LINE; MICROFLUIDIC ANALYSIS;

CAENORHABDITIS ELEGANS; DANIO RERIO; XENOPUS TROPICALIS;

BIOREACTORS; CELL COUNT; CELL CULTURE TECHNIQUES; CELL SEPARATION; ELECTRONICS; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; FLOW CYTOMETRY; HUMANS; JURKAT CELLS; MICROFLUIDIC ANALYTICAL TECHNIQUES;

EID: 77950280317     PISSN: 17486041     EISSN: 1748605X     Source Type: Journal    
DOI: 10.1088/1748-6041/5/2/021001     Document Type: Article

References (23)

1. Spector M 2006 Biomaterials-based tissue engineering and regenerative medicine solutions to musculoskeletal problems Swiss Med. Wkly. 136 293-301
2. Ramseier C A, Abramson Z R, Jin Q and Giannobile W V 2006 Gene therapeutics for periodontal regenerative medicine Dent. Clin. North Am. 50 245-63
3. Jayasinghe S N, Qureshi A N and Eagles P A M 2006 Electrohydrodynamic jet processing: an advanced electric-field-driven jetting phenomenon for processing living cells Small 2 216-9
4. Jayasinghe S N, Eagles P A M and Qureshi A N 2006 Electric field driven jetting: an emerging approach for processing living cells Biotechnol. J. 1 86-94
5. Townsend-Nicholson A and Jayasinghe S N 2006 Cell electrospinning: a unique biotechnique for encapsulating living organisms for generating active biological microthreads/scaffolds Biomacromolecules 7 3364-9
6. Jayasinghe S N, Irvine S and McEwan J R 2007 Cell electrospinning highly concentrated cellular suspensions containing primary living organisms into cell-bearing threads and scaffolds Nanomedicine 2 555-67
7. Taylor G I 1984 Disintegration of water drops in an electric field Proc. R. Soc. A 280 383-97
8. Larrondo L and Manley R S J 1981 Electrostatic fiber spinning from polymer melts: I. Experimental observations on fiber formation and properties J. Polym. Sci. Polym. Phys. Edn 19 909-20
9. Basaran O A 2002 Small-scale free surface flows with breakup: drop formation and emerging applications AIChE J. 48 1842-8
10. Pirlo R K, Dean D M D, Knapp R R and Gao B Z 2006 Cell deposition system based on laser guidance Biotechnol. J. 1 1007-13
11. Arumuganathar S, Irvine S, McEwan J R and Jayasinghe S N 2007 A novel pressure assisted cell spinning protocol for directly processing living primary cells as biologically viable cell-bearing threads to scaffolds and membranes Biomed. Mater. 2 211-9
12. Irvine S, Arumuganathar S, McEwan J R and Jayasinghe S N 2007 Coaxial aerodynamically assisted bio-jets: a versatile paradigm for directly engineering living primary organisms Eng. Life Sci. 7 599-610
13. Nair K, Gandhi M, Khalil S, Yan K C, Marcolongo M, Barbee K and Sun W 2009 Characterization of cell viability during bioprinting processes Biotechnol. J. 4 1168-77
14. deMello A J 2006 Control and detection of chemical reactions in microfluidic systems Nature 442 394-402
15. Hong J 2008 Microfluidic systems for high throughput screening Biochip J. 2 12-26
16. Song H, Chen D L and Ismagilov R F 2006 Reactions in droplets in microfluidic channels Angew. Chem. Int. Ed. Engl. 45 7336-56
17. Gunther A and Jensen K F 2006 Multiphase microfluidics: from flow characteristics to chemical and materials synthesis Lab Chip 6 1487-503
18. Huebner A, Sharma S, Srisa-Art M, Hollfelder F, Edel J B and deMello A J 2008 Microdroplets: a sea of applications? Lab Chip 8 1244-54
19. Hong J, Edel J B and deMello A J 2009 Micro- and nanofluidic systems for high-throughput biological screening Drug Discovery Today 14 134-46
20. Huebner A, Srisa-Art M, Holt D, Abell C, Hollfelder F, deMello A J and Edel J B 2007 Quantitative detection of protein expression in single cells using droplet microfluidics Chem. Commun. 1218-20
21. Thorsen T, Roberts R W, Arnold F H and Quake S R 2001 Dynamic pattern formation in a vesicle-generating microfluidic device Phys. Rev. Lett. 86 4163-6
22. Anna S L, Bontoux N and Stone H A 2003 Formation of dispersions using 'flow focusing' in microchannels Appl. Phys. Lett. 82 364-6
23. Hong J, Choi M, deMello A J and Edel J B 2009 Interfacial tension-mediated droplet fusion in rectangular microchannels Biochip J. 3 203-7