Inductive expression of toll-like receptor 5 (TLR5) and associated downstream signaling molecules following ligand exposure and bacterial infection in the Indian major carp, mrigal (Cirrhinus mrigala)

Fish and Shellfish Immunology

Volumn 32, Issue 1, 2012, Pages 121-131

  Basu, M ^a   Swain, B ^a   Maiti, N K ^a   Routray, P ^a   Samanta, M ^a  

^a CENTRAL INSTITUTE OF FRESHWATER AQUACULTURE   (India)

Author keywords

Cirrhinus mrigala; Edwardsiella tarda; TLR5

Indexed keywords

AEROMONAS HYDROPHILA; BACTERIA (MICROORGANISMS); CIRRHINUS MRIGALA; CYPRINIDAE; EDWARDSIELLA TARDA;

FLAGELLIN; IMMUNOLOGICAL ADJUVANT; LIGAND; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 5; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6;

ANIMAL; ANIMAL DISEASE; ARTICLE; CARP; FISH DISEASE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; GRAM NEGATIVE INFECTION; IMMUNOLOGY; SIGNAL TRANSDUCTION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; CARPS; FISH DISEASES; FLAGELLIN; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GRAM-NEGATIVE BACTERIAL INFECTIONS; LIGANDS; MYELOID DIFFERENTIATION FACTOR 88; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 6; TOLL-LIKE RECEPTOR 5;

EID: 84859255263     PISSN: 10504648     EISSN: 10959947     Source Type: Journal    
DOI: 10.1016/j.fsi.2011.10.031     Document Type: Article

References (42)

1. Aoki T, Takano T, Santos MD, Kondo H, Hirono I. Molecular innate immunity in Teleost fish: review and future perspectives. 5th World Fisheries Congress 2008;263-276.
2. Akira S., Uematsu S., Takeuchi O. Pathogen recognition and innate immunity. Cell 2006, 124:783-801.
3. Magnadottir B. Innate immunity of fish (overview). Fish Shellfish Immunol 2006, 20:137-151.
4. Medzhitov R., Janeway C.A. Innate immunity: the virtues of a nonclonal system of recognition. Cell 1997, 91:295-298.
5. Franchi L., Eigenbrod T., Nunez G. Cutting edge: TNF-α mediated sensitization to ATP and Silica via the NLRP3 inflammasome in the absence of microbial stimulation. J Immunol 2009, 183:792-796.
6. Chen G., Shaw M.H., Kim Y.G., Nunez G. NOD-like receptors: role in innate immunity and inflammatory disease. Annu Rev Pathol Mech 2009, 4:365-398.
7. Akira S., Takeda K. Toll-like receptor signalling. Nat Rev Immunol 2004, 4:499-511.
8. Takeda K., Kaisho T., Akira S. Toll-like receptors. Annu Rev Immunol 2003, 21:335-376.
9. Akira S. Pathogen recognition by innate immunity and its signaling. Proc Jpn Acad Ser B 2009, 85:143-156.
10. Hayashi F., Smith K.D., Ozinsky A., Hawn T.R., Yi E.C., Goodlett D.R., et al. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature 2001, 410:1099-1103.
11. Gewirtz A.T., Navas T.A., Lyons S., Godowski P.J., Madara J.L. Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression. J Immunol 2001, 167:1882-1885.
12. Didierlaurent A., Ferrero I., Otten L.A., Dubois B., Reinhardt M., Carlsen H., et al. Flagellin promotes myeloid differentiation factor 88-dependent development of Th2-type response. J Immunol 2004, 172:6922-6930.
13. Vijay-Kumar M., Aitken J.D., Gewirtz A.T. Toll-like receptor-5: protecting the gut from enteric microbes. Semin Immunopathol 2008, 30:11-21.
14. Kadowaki N., Ho S., Antonenko S., Malefyt R.W., Kastelein R.A., Bazan F., et al. Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens. J Exp Med 2001, 194:863-869.
15. Means T.K., Hayashi F., Smith K.D., Aderem A., Luster A.D. The toll-like receptor 5 stimulus bacterial flagellin induces maturation and chemokine production in human dendritic cells. J Immunol 2003, 170:5165-5175.
16. Oshiumi H., Tsujita T., Shida K., Matsumoto M., Ikeo K., Seya T. Prediction of the prototype of the human toll-like receptor gene family from the pufferfish, Fugu rubripes, genome. Immunogenetics 2003, 54:791-800.
17. Tsoi S., Park K.C., Kay H.H., O'Brien T.J., Podor E., Sun G., et al. Identification of a transcript encoding a soluble form of toll-like receptor 5 (TLR5) in Atlantic salmon during Aeromonas salmonicida infection. Vet Immunol Immunopathol 2006, 109:183-187.
18. Baoprasertkul P., Xu P., Peatman E., Kucuktas H., Liu Z. Divergent toll-like receptors in catfish (Ictalurus punctatus): TLR5S, TLR20, TLR21. Fish Shellfish Immunol 2007, 23:1218-1230.
19. Tsujita T., Tsukada H., Nakao M., Oshiumi H., Matsumoto M., Seya T. Sensing bacterial flagellin by membrane and soluble orthologs of toll-like receptor 5 in rainbow trout (Onchorhynchus mikiss). J Biol Chem 2004, 279:48588-48597.
20. Hwang S.D., Asahi T., Kondo H., Hirono I., Aoki T. Molecular cloning and expression study on toll like receptor 5 paralogs in Japanese flounder, Paralichthys olivaceus. Fish Shellfish Immunol 2010, 29:630-638.
21. Quarterly aquatic animal disease report (Asia and Pacific region) 2003, FAO, NACA.
22. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C (T)) method. Methods 2001, 25:402-408.
23. Kanther M., Rawls J.F. Host-microbe interactions in the developing zebrafish. Curr Opin Immunol 2010, 22:10-19.
24. Huttenhuis H.B., Grou C.P., Taverne-Thiele A.J., Rombout J.H. Carp (Cyprinus carpio L.) innate immune factors are present before hatching. Fish Shellfish Immunol 2006, 20:586-596.
25. Nayak S.P., Mohanty B.R., Mishra J., Rauta P.R., Das A., Eknath A.E., et al. Ontogeny and tissue-specific expression of innate immune related genes in rohu, Labeo rohita (Hamilton). Fish Shellfish Immunol 2011, 30:1197-1201.
26. Yao C.L., Kong P., Wang Z.Y., Ji P.F., Liu X.D., Cai M.Y., et al. Molecular cloning and expression of MyD88 in large yellow croaker, Pseudosciaena crocea. Fish Shellfish Immunol 2009, 26:249-255.
27. Skjæveland I., Iliev D.B., Strandskog G., Jørgensen J.B. Identification and characterization of TLR8 and MyD88 homologs in Atlantic salmon (Salmo salar). Dev Comp Immunol 2009, 33:1011-1017.
28. Takano T., Kondo H., Hirono I., Saito-Taki T., Endo M., Aoki T. Identification and characterization of a myeloid differentiation factor 88 (MyD88) cDNA and gene in Japanese flounder, Paralichthys olivaceus. Dev Comp Immunol 2006, 30:807-816.
29. Li X., Zhu B., Chen N., Hu H., Chen J., Zhang X., et al. Molecular characterization and functional analysis of MyD88 in Chinese soft-shelled turtle Trionyx sinensis. Fish Shellfish Immunol 2010, 30:33-38.
30. Li Y.W., Luo X.C., Dan X.M., Huang X.Z., Qiao W., Zhong Z.P., et al. Orange spotted grouper (Epinephelus coioides) TLR2, MyD88 and IL-1β involved in anti-cryptocaryon irritans response. Fish Shellfish Immunol 2011, 30:1230-1240.
31. Kongchum P., Hallerman E.M., Hulata G., David L., Palti Y. Molecular cloning, characterization and expression analysis of TLR9, MyD88 and TRAF6 genes in common carp (Cyprinus carpio). Fish Shellfish Immunol 2011, 30:361-371.
32. Purcell M.K., Smith K.D., Hood L., Winton J.R., Roach J.C. Conservation of toll-like receptor signaling pathways in teleost fish. Comp Biochem Physiol Part D Genomics Proteomics 2006, 1:77-88.
33. Rebl A., Goldammer T., Fischer U., Köllner B., Seyfert H.M. Characterization of two key molecules of teleost innate immunity from rainbow trout (Oncorhynchus mykiss): MyD88 and SAA. Vet Immunol Immunopathol 2009, 131:122-126.
34. Rebl A., Goldammer T., Seyfert H.M. Toll-like receptor signaling in bony fish. Vet Immunol Immunopathol 2010, 134:139-150.
35. van Aubel R.A., Keestra A.M., Krooshoop D.J., van Eden W., van Putten J.P. Ligand-induced differential cross-regulation of toll-like receptors 2, 4 and 5 in intestinalepithelial cells. Mol Immunol 2007, 44:3702-3714.
36. Cabral E.S., Gelderblom H., Hornung R.L., Munson P.J., Martin R., Marques A.R. Borrelia burgdorferi lipoprotein-mediated TLR2 stimulation causes the down-regulation of TLR5 in human monocytes. J Infect Dis 2006, 193:849-859.
37. Sun J., Fegan P.E., Desai A.S., Madara J.L., Hobert M.E. Flagellin-induced tolerance of the toll-like receptor 5 signaling pathway in polarized intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol 2007, 292:G767-G778.
38. Kawai T., Akira S. The role of pattern-recognition receptors in innate immunity: update on toll-like receptors. Nat Immunol 2010, 11:373-384.
39. Sun J.S., Zhao L., Sun L. Interleukin-8 of Cynoglossus semilaevis is a chemoattractant with immunoregulatory property. Fish Shellfish Immunol 2011, 30:1362-1367.
40. Im J., Jeon J.H., Cho M.K., Woo S.S., Kang S.S., Yun C.H., et al. Induction of IL-8 expression by bacterial flagellin is mediated through lipid raft formation and intracellular TLR5 activation in A549 cells. Mol Immunol 2009, 47:614-622.
41. Van der Sar A.M., Stockhammer O.W., Van der Laan C., Spaink H.P., Bitter W., Meijer A.H. MyD88 innate immune function in a zebrafish embryo infection model. Infect Immun 2006, 74:2436-2441.
42. Wei Y.C., Pan T.S., Chang M.X., Huang B., Xu Z., Luo T.R., et al. Cloning and expression of toll-like receptors 1 and 2 from a teleost fish, the orange-spotted grouper Epinephelus coioides. Vet Immunol Immunopathol 2011, 141:173-182.