Induction of IL-8 expression by bacterial flagellin is mediated through lipid raft formation and intracellular TLR5 activation in A549 cells

Molecular Immunology

Volumn 47, Issue 2-3, 2009, Pages 614-622

  Im, Jintaek ^a   Jeon, Jun Ho ^a   Cho, Min Kyung ^a   Woo, Sang Su ^a   Kang, Seok Seong ^a   Yun, Cheol Heui ^b   Lee, Kangseok ^c   Chung, Dae Kyun ^d,e   Han, Seung Hyun ^a,f  

^a Seoul National University   (South Korea)

^b Seoul National University   (South Korea)

^c Chung Ang University   (South Korea)

^d Kyung Hee University   (South Korea)

^e RNA Inc   (South Korea)

^f International Vaccine Institute   (South Korea)

Author keywords

A549; Flagellin; IL 8; Lipid rafts; Toll like receptor 5

Indexed keywords

CHLORPROMAZINE; FLAGELLIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; NUCLEAR FACTOR INTERLEUKIN 6 TRANSCRIPTION FACTOR; NYSTATIN; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; TOLL LIKE RECEPTOR 5; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS SUBTILIS; CELL STRAIN HEK293; CELL SURFACE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ESCHERICHIA COLI; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIPID RAFT; LUNG ALVEOLUS CELL TYPE 2; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; RECEPTOR UPREGULATION; REPORTER GENE; SIGNAL TRANSDUCTION;

BACILLUS SUBTILIS; BRONCHI; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELL LINE, TUMOR; CYTOPLASM; ENZYME ACTIVATION; EPITHELIAL CELLS; FLAGELLIN; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-8; INTRACELLULAR SPACE; MEMBRANE MICRODOMAINS; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PROTEIN KINASE C; RNA, MESSENGER; SALMONELLA TYPHIMURIUM; TIME FACTORS; TOLL-LIKE RECEPTOR 5; TRANSCRIPTION, GENETIC;

BACTERIA (MICROORGANISMS);

EID: 70450245112     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2009.09.004     Document Type: Article

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