Coenzyme Q 10, vitamin E, selenium, and methionine in the treatment of chronic recurrent viral mucocutaneous infections

Nutrition

Volumn 28, Issue 5, 2012, Pages 509-514

  De Luca, Chiara ^a   Kharaeva, Zaira ^b   Raskovic, Desanka ^a   Pastore, Palmira ^a   Luci, Antonio ^a   Korkina, Liudmila ^a  

^a LABORATORIO DI PATOLOGIA VASCOLARE   (Italy)

^b Medical University   (Russian Federation)

Author keywords

Coenzyme Q; Herpes; Human papillomavirus; L methionine; Peroxynitrite; Selenium; Vitamin E

Indexed keywords

ACICLOVIR; ALPHA INTERFERON; ALPHA TOCOPHEROL; ANTIOXIDANT; CYTOKINE; GAMMA INTERFERON; GLUTATHIONE; METHIONINE; NUTRACEUTICAL; PEROXYNITRITE; PLACEBO; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; SELENIUM ASPARTATE; UBIDECARENONE; UNCLASSIFIED DRUG; VIRUS DNA;

ADULT; ARTICLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; CRYOTHERAPY; DOUBLE BLIND PROCEDURE; DRUG ERUPTION; DRUG POTENTIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEASIBILITY STUDY; FEMALE; GENITAL HERPES; HEALING; HERPES ZOSTER; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MONOTHERAPY; NUTRITIONAL SUPPORT; OPEN STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL; RECURRENT INFECTION; RISK REDUCTION; VERRUCA VULGARIS; VIRAL SKIN DISEASE; VIRUS LOAD;

ACYCLOVIR; ADMINISTRATION, ORAL; ADULT; ALPHA-TOCOPHEROL; ALPHAPAPILLOMAVIRUS; ANTIOXIDANTS; ANTIVIRAL AGENTS; CHRONIC DISEASE; CRYOTHERAPY; DIETARY SUPPLEMENTS; DNA VIRUS INFECTIONS; DNA, VIRAL; DOUBLE-BLIND METHOD; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HERPES GENITALIS; HERPES ZOSTER; HOST-PATHOGEN INTERACTIONS; HUMANS; MALE; METHIONINE; MIDDLE AGED; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; RECURRENCE; SELENIUM; SKIN DISEASES, INFECTIOUS; UBIQUINONE; VIRAL LOAD; VITAMIN E; YOUNG ADULT;

DNA VIRUSES; HERPES; HERPES ZOSTER; HUMAN PAPILLOMAVIRUS;

EID: 84859217765     PISSN: 08999007     EISSN: 18731244     Source Type: Journal    
DOI: 10.1016/j.nut.2011.08.003     Document Type: Article

References (40)

1. Strasfeld L., Chou S. Antiviral drug resistance: mechanisms and clinical implications. Infect Dis Clin North Am 2010, 24:809-833.
2. Micali G., Dall'Oglio F., Nasca M.R., Tedeschi A. Management of cutaneous warts: an evidence-based approach. Am J Clin Dermatol 2004, 5:311-317.
3. Akaike T., Maeda H. Nitric oxide and virus infection. Immunology 2000, 101:300-308.
4. Zaki M.H., Akuta T., Akaike T. Nitric oxide-induced nitrative stress involved in microbial pathogenesis. J Pharmacol Sci 2005, 98:117-129.
5. Peterhans E. Oxidants and antioxidants in viral diseases: disease mechanism and metabolic regulation. J Nutr 1997, 127:962S-965S.
6. Skulachev V.P. Possible role of reactive oxygen species in antiviral defense. Biochemistry (Mosc) 1998, 63:1438-1440.
7. McFadden G. Even viruses can learn to cope with stress. Science 1998, 279:40-41.
8. Schwarz K.B. Oxidative stress during viral infection: a review. Free Radic Biol Med 1996, 21:641-649.
9. Dianzani F., Baron S. Nonspecific defenses. Medical Microbiology 1996, University of Texas Medical Branch at Galveston, Galveston (TX), chapter 49. 4th ed. S. Baron (Ed.).
10. Akaike T. Role of free radicals in viral pathogenesis and mutation. Rev Med Virol 2001, 11:87-101.
11. Sheridan P.A., Beck M.A. The immune response to herpes simplex virus encephalitis in mice is modulated by dietary vitamin E. J Nutr 2008, 138:130-137.
12. Faith S.A., Sweet T.J., Bailey E., Booth T., Docherty J.J. Resveratrol suppresses nuclear factor-[kappa] B in herpes simplex virus infected cells. Antiviral Res 2006, 72:242-251.
13. Beck M.A. Rapid genomic evolution of a non-virulent coxsackievirus B3 in mice due to vitamin E or selenium-deficient mice. Biomed Environ Sci 1997, 10:307-315.
14. Beck M.A., Matthews C.C. Micronutrients and host resistance to viral infection. Proc Nutr Soc 2000, 59:581-585.
15. Beck M.A. Antioxidants and viral infections: host immune response and viral pathogenicity. J Am Coll Nutr 2001, 20:384-388S.
16. Sepúlveda R.T., Zhang J., Watson R.R. Selenium supplementation decreases coxsackievirus heart disease during murine AIDS. Cardiovasc Toxicol 2002, 2:53-61.
17. Gach J.E., Humphreys F., Berth-Jones J. Randomized, double-blind, placebo-controlled pilot study to assess the value of free radical scavengers in reducing inflammation induced by cryotherapy. Clin Exp Dermatol 2005, 30:14-16.
18. Ayres S., Mihan R. Letter: Post-herpes zoster neuralgia: response to vitamin E therapy. Arch Dermatol 1973, 108:855-856.
19. Cassano N., Ferrari A., Fai D., Pettinato M., Pellè S., Del Brocco L., et al. Oral supplementation with a nutriceutical containing Echinacea, methionine and antioxidant/immunostimulating compounds in patients with cutaneous viral warts. G Ital Dermatol Venereol 2011, 146:191-195.
20. Murphy R.F., Caliendo A.M. Relative quantity of cerebrospinal fluid herpes simplex virus DNA in adult cases of encephalitis and meningitis. Am J Clin Pathol 2009, 132:687-690.
21. Strick L.B., Wald A. Diagnostics for herpes simplex virus: is PCR the new gold standard?. Mol Diagn Ther 2006, 10:17-28.
22. Giovannoni G., Land J.M., Keir G., Thompson E.J., Heales S.J. Adaptation of the nitrate reductase and Griess reaction methods for the measurement of serum nitrate plus nitrite levels. Ann Clin Biochem 1997, 34:193-198.
23. De Luca C., Scordo M.G., Cesareo E., Pastore S., Mariani S., Maiani G. Biological definition of multiple chemical sensitivity from redox state and cytokine profiling and not from polymorphisms of xenobiotic-metabolizing enzymes. Toxicol Appl Pharmacol 2010, 248:285-292.
24. De Luca C., Deeva I., Mariani S., Maiani G., Stancato A., Korkina L. Monitoring antioxidant defenses and free radical production in space-flight, aviation and railway engine operators, for the prevention and treatment of oxidative stress, immunological impairment and pre-mature cell aging. Toxicol Ind Health 2009, 25:259-267.
25. Reed D.J., Babson J.R., Beatty P.W., Brodie A.E., Ellis W.W., Potter D.W. High performance liquid chromatography analysis of nanomole levels of glutathione disulphide and related thiols and disulphides. Anal Biochem 1980, 106:55-62.
26. Korkina L.G., Samochatova E.V., Maschan A.A., Suslova T.B., Cheremisina Z.P., Afanas'ev I.B. Release of active oxygen radicals by leukocytes of Fanconi anemia patients. J Leukoc Biol 1992, 52:357-362.
27. Fridovich I. Cytochrome c. Handbook of Methods for Oxygen Radical Research 1985, 121-122. CRC Press, Boca Raton, FL. R.A. Greenwald (Ed.).
28. Korkina L., Deeva I., Ibragimova G., Shakula A., Luci A., De Luca C. Coenzyme Q10-containing composition (Immugen) protects against occupational and environmental stress in workers of the gas and oil industry. Biofactors 2003, 18:245-254.
29. Colasanti M., Persichini T., Venturini G., Ascenzi P. S-nitrosylation of viral proteins: molecular bases for antiviral effect of nitric oxide. IUBMB Life 1999, 48:25-31.
30. Sasmaz S., Arican O., Kurutas E.B. Oxidative stress in patients with nongenital warts. Mediators Inflamm 2005, 2005:233-236.
31. Schachtele S.J., Hu S., Little M.R., Lokensgard J.R. Herpes simplex virus induces neural oxidative damage via microglial cell Toll-like receptor-2. J Neuroinflamm 2010, 7:35.
32. Wu G., Fang Y.Z., Yang S., Lupton J.R., Turner N.D. Glutathione metabolism and its implications for health. J Nutr 2004, 134:489-492.
33. Niki E. Mechanisms and dynamics of antioxidant action of ubiquinol. Mol Aspects Med 1997, 18:S63-S70.
34. Schöpfer F., Riobó N., Carreras M.C., Alvarez B., Radi R., Boveris A. Oxidation of ubiquinol by peroxynitrite: implications for protection of mitochondria against nitrosative damage. Biochem J 2000, 349:35-42.
35. 10, a cutaneous antioxidant and energizer. Biofactors 1999, 9:371-378.
36. Jozsef L., Filep J.G. Selenium-containing compounds attenuate peroxynitrite-mediated NF-kappaB and AP-1 activation and interleukin-8 gene and protein expression in human leukocytes. Free Radic Biol Med 2003, 35:1018-1027.
37. Sheridan J., Kern E., Martin A., Booth A. Evaluation of antioxidant healing formulations in topical therapy of experimental cutaneous and genital herpes simplex virus infections. Antiviral Res 1997, 36:157-166.
38. De Luca C., Valacchi G. Surface lipids as multifunctional mediators of skin responses to environmental stimuli. Mediators Inflamm 2010, 2010:321-494.
39. Harpaz R., Ortega-Sanchez I.R., Seward J.F. Advisory Committee on Immunization Practices (ACIP) Centers for Disease Control and Prevention (CDC). Prevention of herpes zoster: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 2008, 57(RR-5):1-3.
40. Müller A.C., Maharaj H., Maharaj D.S., Daya S. Acyclovir protects against quinolinic-acid-induced oxidative neurotoxicity. J Pharm Pharmacol 2005, 57:883-888.