A combined approach of vesicle formulations and microneedle arrays for transcutaneous immunization against hepatitis B virus

European Journal of Pharmaceutical Sciences

Volumn 46, Issue 1-2, 2012, Pages 1-7

  Hirschberg, Hoang ^a   Van Kuijk, Sandra ^a   Loch, Jessica ^a   Jiskoot, Wim ^b   Bouwstra, Joke ^b   Kersten, Gideon ^a   Amorij, Jean Pierre ^a  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Elastic vesicles; Hepatits B vaccine; Microneedles; Transcutaneous immunization

Indexed keywords

CHOLERA TOXIN; DRUG CARRIER; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B VACCINE; L595 VESICLE; OCTAOXYETHYLENE LAURATE ESTER; PHOSPHATIDYLCHOLINE; SPC VESICLE; SUCROSE ESTER DERIVATIVE; SUCROSE LAURATE ESTER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIBODY BLOOD LEVEL; ANTIBODY RESPONSE; ARTICLE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG MANUFACTURE; ELASTICITY; FEMALE; IMMUNIZATION; IMMUNOGENICITY; IN VITRO STUDY; IN VIVO STUDY; MICRONEEDLE; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; SEROCONVERSION; SOYBEAN; TRANSCUTANEOUS IMMUNIZATION; ZETA POTENTIAL;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, CUTANEOUS; ANIMALS; CHOLERA TOXIN; CHROMATOGRAPHY, GEL; FEMALE; HEPATITIS B; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HEXOSES; IMMUNOGLOBULIN G; LAURATES; LIPOSOMES; MICE; MICE, INBRED BALB C; PARTICLE SIZE; PHOSPHATIDYLCHOLINES; POLYETHYLENE GLYCOLS; SKIN; SUCROSE; VACCINATION;

EID: 84859211043     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2012.01.013     Document Type: Article

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