메뉴 건너뛰기




Volumn 6, Issue 5, 2007, Pages 809-819

Transcutaneous immunization with heat-labile enterotoxin: Development of a needle-free vaccine patch

Author keywords

Immunostimulant; Langerhans' cell; Patch; Transcutaneous immunization

Indexed keywords

BACTERIAL DNA; CHOLERA TOXIN; CYTOKINE; CYTOKINE RECEPTOR AGONIST; ESCHERICHIA COLI ENTEROTOXIN; EXOTOXIN; INFLUENZA VIRUS HEMAGGLUTININ; LIPOPOLYSACCHARIDE; NICOTINE; PARACETAMOL; TETANUS TOXOID; TOLL LIKE RECEPTOR 7 AGONIST; TOLL LIKE RECEPTOR 8 AGONIST; UNCLASSIFIED DRUG;

EID: 35348938134     PISSN: 14760584     EISSN: 17448395     Source Type: Journal    
DOI: 10.1586/14760584.6.5.809     Document Type: Review
Times cited : (61)

References (72)
  • 1
    • 1342268100 scopus 로고    scopus 로고
    • Use of the inactivated intranasal influenza vaccine and the risk of Bell's palsy in Switzerland
    • Mutsch M, Zhou W, Rhodes P et al. Use of the inactivated intranasal influenza vaccine and the risk of Bell's palsy in Switzerland. N. Engl. J. Med. 350(9), 896-903 (2004).
    • (2004) N. Engl. J. Med , vol.350 , Issue.9 , pp. 896-903
    • Mutsch, M.1    Zhou, W.2    Rhodes, P.3
  • 2
    • 0033794923 scopus 로고    scopus 로고
    • A proposal for safety standards for human use of cholera toxin (or Escherichia coli heat-labile enterotoxin) derivatives as an adjuvant of nasal inactivated influenza vaccine
    • Tamura SI, Kurata T. A proposal for safety standards for human use of cholera toxin (or Escherichia coli heat-labile enterotoxin) derivatives as an adjuvant of nasal inactivated influenza vaccine. Jpn. J. Infect. Dis. 53(3), 98-106 (2000).
    • (2000) Jpn. J. Infect. Dis , vol.53 , Issue.3 , pp. 98-106
    • Tamura, S.I.1    Kurata, T.2
  • 3
    • 0038330365 scopus 로고    scopus 로고
    • Nonclinical safety evaluation of Escherichia coli heat-labile toxin mucosal adjuvant as a component of a nasal influenza vaccine
    • Zurbriggen R, Metcalfe IC, Glück R, Viret J-F, Moser C. Nonclinical safety evaluation of Escherichia coli heat-labile toxin mucosal adjuvant as a component of a nasal influenza vaccine. Expert Rev. Vaccines 2(2), 295-304 (2003).
    • (2003) Expert Rev. Vaccines , vol.2 , Issue.2 , pp. 295-304
    • Zurbriggen, R.1    Metcalfe, I.C.2    Glück, R.3    Viret, J.-F.4    Moser, C.5
  • 5
    • 0037369748 scopus 로고    scopus 로고
    • Mutant Escherichia coli heat-labile toxin B subunit that separates toxoid-mediated signaling and immunomodulatory action from trafficking and delivery functions
    • Fraser SA, de Haan L, Hearn AR et al. Mutant Escherichia coli heat-labile toxin B subunit that separates toxoid-mediated signaling and immunomodulatory action from trafficking and delivery functions. Infect. Immun. 71(3), 1527-1537 (2003).
    • (2003) Infect. Immun , vol.71 , Issue.3 , pp. 1527-1537
    • Fraser, S.A.1    de Haan, L.2    Hearn, A.R.3
  • 6
    • 0035925699 scopus 로고    scopus 로고
    • Transcutaneous immunization: T-cell responses and boosting of existing immunity
    • Hammond SA, Walwender D, Alving CR, Glenn GM. Transcutaneous immunization: T-cell responses and boosting of existing immunity. Vaccine 19, 2701-2707 (2001).
    • (2001) Vaccine , vol.19 , pp. 2701-2707
    • Hammond, S.A.1    Walwender, D.2    Alving, C.R.3    Glenn, G.M.4
  • 7
    • 0037405186 scopus 로고    scopus 로고
    • Immunostimulant patch containing heat labile enterotoxin from E. coli enhances immune responses to injected influenza vaccine through activation of skin dendritic cells
    • Guebre-Xabier M, Hammond SA, Epperson DE, Yu J, Ellingsworth L, Glenn GM. Immunostimulant patch containing heat labile enterotoxin from E. coli enhances immune responses to injected influenza vaccine through activation of skin dendritic cells. J. Virol. 77(9), 5218-5225 (2003).
    • (2003) J. Virol , vol.77 , Issue.9 , pp. 5218-5225
    • Guebre-Xabier, M.1    Hammond, S.A.2    Epperson, D.E.3    Yu, J.4    Ellingsworth, L.5    Glenn, G.M.6
  • 8
    • 0028827001 scopus 로고
    • Cyclic AMP signaling pathways are important in IL-1 β transcriptional regulation
    • Chandra G, Cogswell JP, Miller LR et al. Cyclic AMP signaling pathways are important in IL-1 β transcriptional regulation. J. Immunol. 155(10), 4535-4543 (1995).
    • (1995) J. Immunol , vol.155 , Issue.10 , pp. 4535-4543
    • Chandra, G.1    Cogswell, J.P.2    Miller, L.R.3
  • 9
    • 0032858430 scopus 로고    scopus 로고
    • Cyclic adenosine monophosphate-responsive elements are involved in the transcriptional activation of the human IL-10 gene in monocytic cells
    • Platzer C, Fritsch E, Elsner T, Lehmann MH, Volk HD, Prosch S. Cyclic adenosine monophosphate-responsive elements are involved in the transcriptional activation of the human IL-10 gene in monocytic cells. Eur. J. Immunol. 29(10), 3098-3104 (1999).
    • (1999) Eur. J. Immunol , vol.29 , Issue.10 , pp. 3098-3104
    • Platzer, C.1    Fritsch, E.2    Elsner, T.3    Lehmann, M.H.4    Volk, H.D.5    Prosch, S.6
  • 11
    • 0019450641 scopus 로고
    • High affinity binding of tetanus toxin to mammalian brain membranes
    • Rogers TB, Snyder SH. High affinity binding of tetanus toxin to mammalian brain membranes. J. Biol. Chem. 256(5), 2402-2407 (1981).
    • (1981) J. Biol. Chem , vol.256 , Issue.5 , pp. 2402-2407
    • Rogers, T.B.1    Snyder, S.H.2
  • 12
    • 33745852791 scopus 로고    scopus 로고
    • GM1-binding deficient exotoxin is a potent non-inflammatory broad-spectrum intradermal immunoadjuvant
    • Zoeteweij J-P, Epperson DE, Porter JD et al. GM1-binding deficient exotoxin is a potent non-inflammatory broad-spectrum intradermal immunoadjuvant. J. Immunol. 177(2), 1197-1207 (2006).
    • (2006) J. Immunol , vol.177 , Issue.2 , pp. 1197-1207
    • Zoeteweij, J.-P.1    Epperson, D.E.2    Porter, J.D.3
  • 13
    • 0037992894 scopus 로고    scopus 로고
    • Mutants of the Escherichia coli heat-labile enterotoxin as safe and strong adjuvants for intranasal delivery of vaccines
    • Peppoloni S, Ruggiero P, Contorni M et al. Mutants of the Escherichia coli heat-labile enterotoxin as safe and strong adjuvants for intranasal delivery of vaccines. Expert Rev. Vaccines 2(2), 285-293 (2003).
    • (2003) Expert Rev. Vaccines , vol.2 , Issue.2 , pp. 285-293
    • Peppoloni, S.1    Ruggiero, P.2    Contorni, M.3
  • 14
    • 3142769174 scopus 로고    scopus 로고
    • Immunostimulant patch enhances immune responses to influenza vaccine in aged mice
    • Guebre-Xabier M, Hammond SA, Ellingsworth LR, Glenn GM. Immunostimulant patch enhances immune responses to influenza vaccine in aged mice. J. Virol. 78(14), 7610-7618 (2004).
    • (2004) J. Virol , vol.78 , Issue.14 , pp. 7610-7618
    • Guebre-Xabier, M.1    Hammond, S.A.2    Ellingsworth, L.R.3    Glenn, G.M.4
  • 15
    • 1642272033 scopus 로고    scopus 로고
    • Transcutaneous immunization induces mucosal CTLs and protective immunity by migration of primed skin dendritic cells
    • Belyakov IM, Hammond SA, Ahlers JD, Glenn GM, Berzofsky JA. Transcutaneous immunization induces mucosal CTLs and protective immunity by migration of primed skin dendritic cells. J. Clin. Invest. 113, 998-1007 (2004).
    • (2004) J. Clin. Invest , vol.113 , pp. 998-1007
    • Belyakov, I.M.1    Hammond, S.A.2    Ahlers, J.D.3    Glenn, G.M.4    Berzofsky, J.A.5
  • 16
    • 34249891873 scopus 로고    scopus 로고
    • Transcutaneous immunization with Clostridium difficile toxoid A induces systemic and mucosal immune responses and toxin A neutralizing antibodies in mice
    • Ghose C, Kalsy A, Shiekh A et al. Transcutaneous immunization with Clostridium difficile toxoid A induces systemic and mucosal immune responses and toxin A neutralizing antibodies in mice. Infect. Immun. 75, 2826-2832 (2007).
    • (2007) Infect. Immun , vol.75 , pp. 2826-2832
    • Ghose, C.1    Kalsy, A.2    Shiekh, A.3
  • 17
    • 0034528538 scopus 로고    scopus 로고
    • Transcutaneous immunization: A human vaccine delivery strategy using a patch
    • Glenn GM, Taylor DN, Li X, Frankel S, Montemarano A, Alving CR. Transcutaneous immunization: a human vaccine delivery strategy using a patch. Nat. Med. 6(12), 1403-1406 (2000).
    • (2000) Nat. Med , vol.6 , Issue.12 , pp. 1403-1406
    • Glenn, G.M.1    Taylor, D.N.2    Li, X.3    Frankel, S.4    Montemarano, A.5    Alving, C.R.6
  • 18
    • 3943056060 scopus 로고    scopus 로고
    • Induction of protective immunity against lethal anthrax challenge with a patch
    • Kenney R, Yu J, Guebre-Xabier M et al. Induction of protective immunity against lethal anthrax challenge with a patch. J. Infect. Dis. 190, 774-782 (2004).
    • (2004) J. Infect. Dis , vol.190 , pp. 774-782
    • Kenney, R.1    Yu, J.2    Guebre-Xabier, M.3
  • 19
    • 34247156074 scopus 로고    scopus 로고
    • Transcutaneous immunization with the heat-labile toxin (LT) of enterotoxigenic Escherichia coli (ETEC): Protective efficacy in a double-blind, placebo-controlled challenge study
    • McKenzie R, Bourgeois AL, Frech SA et al. Transcutaneous immunization with the heat-labile toxin (LT) of enterotoxigenic Escherichia coli (ETEC): protective efficacy in a double-blind, placebo-controlled challenge study. Vaccine 25(18), 3684-3691 (2007).
    • (2007) Vaccine , vol.25 , Issue.18 , pp. 3684-3691
    • McKenzie, R.1    Bourgeois, A.L.2    Frech, S.A.3
  • 20
    • 0036178064 scopus 로고    scopus 로고
    • Transcutaneous immunization using colonization factor and heat labile enterotoxin induces correlates of protective immunity for enterotoxigenic Escherichia coli
    • Yu J, Cassels F, Scharton-Kersten T et al. Transcutaneous immunization using colonization factor and heat labile enterotoxin induces correlates of protective immunity for enterotoxigenic Escherichia coli. Infect. Immun. 70(3), 1056-1068 (2002).
    • (2002) Infect. Immun , vol.70 , Issue.3 , pp. 1056-1068
    • Yu, J.1    Cassels, F.2    Scharton-Kersten, T.3
  • 21
    • 33846391608 scopus 로고    scopus 로고
    • Regulation of intestinal immunity: Effects of the oral adjuvant Escherichia coli heat-labile enterotoxin on migrating dendritic cells
    • Milling SW, Yrlid U, Jenkins C, Richards CM, Williams NA, MacPherson G. Regulation of intestinal immunity: effects of the oral adjuvant Escherichia coli heat-labile enterotoxin on migrating dendritic cells. Eur. J. Immunol. 37(1), 87-99 (2007).
    • (2007) Eur. J. Immunol , vol.37 , Issue.1 , pp. 87-99
    • Milling, S.W.1    Yrlid, U.2    Jenkins, C.3    Richards, C.M.4    Williams, N.A.5    MacPherson, G.6
  • 22
    • 0032539614 scopus 로고    scopus 로고
    • Mucosal immunization with HIV-1 peptide vaccine induces mucosal and systemic cytotoxic T lymphocytes and protective immunity in mice against intrarectal recombinant HIV-vaccinia challenge
    • Belyakov IM, Derby MA, Ahlers JD et al. Mucosal immunization with HIV-1 peptide vaccine induces mucosal and systemic cytotoxic T lymphocytes and protective immunity in mice against intrarectal recombinant HIV-vaccinia challenge. Proc. Natl Acad. Sci. USA 95(4), 1709-1714 (1998).
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , Issue.4 , pp. 1709-1714
    • Belyakov, I.M.1    Derby, M.A.2    Ahlers, J.D.3
  • 23
    • 33947195588 scopus 로고    scopus 로고
    • Mass vaccination: Solutions in the skin
    • Plotkin SA Ed, Springer Verlag, Berlin-Heidelberg, Germany
    • Glenn GM, Kenney RT. Mass vaccination: solutions in the skin. In: Mass Vaccination: Global Aspects -Progress and Obstacles. Plotkin SA (Ed.). Springer Verlag, Berlin-Heidelberg, Germany 247-268 (2006).
    • (2006) Mass Vaccination: Global Aspects -Progress and Obstacles , pp. 247-268
    • Glenn, G.M.1    Kenney, R.T.2
  • 24
    • 33846854208 scopus 로고    scopus 로고
    • In vivo estimation of stratum corneum thickness from water concentration profiles obtained with Raman spectroscopy
    • Egawa M, Hirao T, Takahashi M. In vivo estimation of stratum corneum thickness from water concentration profiles obtained with Raman spectroscopy. Acta Derm. Venereol. 87(1), 4-8 (2007).
    • (2007) Acta Derm. Venereol , vol.87 , Issue.1 , pp. 4-8
    • Egawa, M.1    Hirao, T.2    Takahashi, M.3
  • 25
    • 0344826779 scopus 로고    scopus 로고
    • Epidermal thickness at different body sites: Relationship to age, gender, pigmentation, blood content, skin type and smoking habits
    • Sandby-Moller J, Poulsen T, Wulf HC. Epidermal thickness at different body sites: relationship to age, gender, pigmentation, blood content, skin type and smoking habits. Acta Derm. Venereol. 83(6), 410-413 (2003).
    • (2003) Acta Derm. Venereol , vol.83 , Issue.6 , pp. 410-413
    • Sandby-Moller, J.1    Poulsen, T.2    Wulf, H.C.3
  • 26
    • 0023882897 scopus 로고
    • The validity and practicality of sun-reactive skin types I through VI
    • Fitzpatrick TB. The validity and practicality of sun-reactive skin types I through VI. Arch. Dermatol. 124(6), 869-871 (1988).
    • (1988) Arch. Dermatol , vol.124 , Issue.6 , pp. 869-871
    • Fitzpatrick, T.B.1
  • 27
    • 0034988830 scopus 로고    scopus 로고
    • Topographic variations in normal skin, as viewed by in vivo reflectance confocal microscopy
    • Huzaira M, Rius F, Rajadhyaksha M, Anderson RR, Gonzalez S. Topographic variations in normal skin, as viewed by in vivo reflectance confocal microscopy. J. Invest. Dermatol. 116(6), 846-852 (2001).
    • (2001) J. Invest. Dermatol , vol.116 , Issue.6 , pp. 846-852
    • Huzaira, M.1    Rius, F.2    Rajadhyaksha, M.3    Anderson, R.R.4    Gonzalez, S.5
  • 29
    • 0033250953 scopus 로고    scopus 로고
    • Epidermal Langerhans cells: From neurons to nature's adjuvants
    • Jakob T, Udey MC. Epidermal Langerhans cells: from neurons to nature's adjuvants. Adv. Dermatol. 14, 209-258 (1999).
    • (1999) Adv. Dermatol , vol.14 , pp. 209-258
    • Jakob, T.1    Udey, M.C.2
  • 30
    • 0027985488 scopus 로고
    • Morphological and quantitative analyses of normal epidermal Langerhans cells using confocal scanning laser microscopy
    • Yu RC, Abrams DC, Alaibac M, Chu AC. Morphological and quantitative analyses of normal epidermal Langerhans cells using confocal scanning laser microscopy. Br. J. Dermatol. 131(6), 843-848 (1994).
    • (1994) Br. J. Dermatol , vol.131 , Issue.6 , pp. 843-848
    • Yu, R.C.1    Abrams, D.C.2    Alaibac, M.3    Chu, A.C.4
  • 32
    • 0031024215 scopus 로고    scopus 로고
    • Cadherins and Langerhans cell immunobiology
    • Udey MC. Cadherins and Langerhans cell immunobiology. Clin. Exp. Immunol. 107(Suppl. 1), 6-8 (1997).
    • (1997) Clin. Exp. Immunol , vol.107 , Issue.SUPPL. 1 , pp. 6-8
    • Udey, M.C.1
  • 33
    • 0036128539 scopus 로고    scopus 로고
    • Safety and immunogenicity of a prototype enterotoxigenic Escherichia coli vaccine administered transcutaneously
    • Güereña-Burgueño F, Hall ER, Taylor DN et al. Safety and immunogenicity of a prototype enterotoxigenic Escherichia coli vaccine administered transcutaneously. Infect. Immun. 70(4), 1874-1880 (2002).
    • (2002) Infect. Immun , vol.70 , Issue.4 , pp. 1874-1880
    • Güereña-Burgueño, F.1    Hall, E.R.2    Taylor, D.N.3
  • 34
    • 0003995677 scopus 로고    scopus 로고
    • O'Hagan DT Ed, Humana Press, Inc, NJ, USA
    • O'Hagan DT (Ed.). Methods in Molecular Medicine. Humana Press, Inc., NJ, USA (2000).
    • (2000) Methods in Molecular Medicine
  • 35
    • 34248376426 scopus 로고    scopus 로고
    • Safety and immunogenicity of an ETEC vaccine patch containing heat-labile toxin: Use of skin pretreatment to disrupt the stratum corneum
    • Glenn GM, Villar CP, Flyer DC et al. Safety and immunogenicity of an ETEC vaccine patch containing heat-labile toxin: use of skin pretreatment to disrupt the stratum corneum. Infect. Immun. 75(5), 2163-2170 (2007).
    • (2007) Infect. Immun , vol.75 , Issue.5 , pp. 2163-2170
    • Glenn, G.M.1    Villar, C.P.2    Flyer, D.C.3
  • 36
    • 35348955180 scopus 로고    scopus 로고
    • Controlled, single-step, stratum corneum disruption as a pretreatment for immunization via a patch
    • In Press
    • Frerichs DM, Frech SA, Flyer DC, Yu J, Glenn GM. Controlled, single-step, stratum corneum disruption as a pretreatment for immunization via a patch. Vaccine (In Press).
    • Vaccine
    • Frerichs, D.M.1    Frech, S.A.2    Flyer, D.C.3    Yu, J.4    Glenn, G.M.5
  • 38
    • 0034072432 scopus 로고    scopus 로고
    • Safety and immunogenicity of intranasally administered inactivated trivalent virosome-formulated influenza vaccine containing Escherichia coli heat-labile toxin as a mucosal adjuvant
    • Glück R, Mischler R, Durrer P et al. Safety and immunogenicity of intranasally administered inactivated trivalent virosome-formulated influenza vaccine containing Escherichia coli heat-labile toxin as a mucosal adjuvant. J. Infect. Dis. 181(3), 1129-1132 (2000).
    • (2000) J. Infect. Dis , vol.181 , Issue.3 , pp. 1129-1132
    • Glück, R.1    Mischler, R.2    Durrer, P.3
  • 39
    • 0016632660 scopus 로고
    • Test for enterotoxigenic Escherichia coli using Y-1 adrenal cells in miniculture
    • Sack DA, Sack RB. Test for enterotoxigenic Escherichia coli using Y-1 adrenal cells in miniculture. Infect. Immun. 11(2), 334-336 (1975).
    • (1975) Infect. Immun , vol.11 , Issue.2 , pp. 334-336
    • Sack, D.A.1    Sack, R.B.2
  • 43
    • 3142618960 scopus 로고    scopus 로고
    • A stability program for the distribution of drug products
    • Lucas TI, Bishara RH, Seervers RH. A stability program for the distribution of drug products. Pharm. Technol. 2, 68-73 (2004).
    • (2004) Pharm. Technol , vol.2 , pp. 68-73
    • Lucas, T.I.1    Bishara, R.H.2    Seervers, R.H.3
  • 44
    • 0034003998 scopus 로고    scopus 로고
    • Effects of IL-12 on immune responses induced by transcutaneous immunization with antigens formulated in a novel lipid-based biphasic delivery system
    • Baca-Estrada ME, Foldvari M, Ewen C, Badea I, Babiuk LA. Effects of IL-12 on immune responses induced by transcutaneous immunization with antigens formulated in a novel lipid-based biphasic delivery system. Vaccine 18(17), 1847-1854 (2000).
    • (2000) Vaccine , vol.18 , Issue.17 , pp. 1847-1854
    • Baca-Estrada, M.E.1    Foldvari, M.2    Ewen, C.3    Badea, I.4    Babiuk, L.A.5
  • 45
    • 0035815553 scopus 로고    scopus 로고
    • Adjuvantation of epidermal powder immunization
    • Chen D, Erickson CA, Endres RL et al. Adjuvantation of epidermal powder immunization. Vaccine 19(20-22), 2908-2917 (2001).
    • (2001) Vaccine , vol.19 , Issue.20-22 , pp. 2908-2917
    • Chen, D.1    Erickson, C.A.2    Endres, R.L.3
  • 46
    • 0032568114 scopus 로고    scopus 로고
    • Skin immunization made possible by cholera toxin
    • Glenn GM, Rao M, Matyas GR, Alving CR. Skin immunization made possible by cholera toxin. Nature 391(6670), 851 (1998).
    • (1998) Nature , vol.391 , Issue.6670 , pp. 851
    • Glenn, G.M.1    Rao, M.2    Matyas, G.R.3    Alving, C.R.4
  • 47
    • 0033864920 scopus 로고    scopus 로고
    • Transcutaneous immunization with bacterial ADP-ribosylating exotoxins, subunits, and unrelated adjuvants
    • Scharton-Kersten T, Yu J, Vassell R, O'Hagan D, Alving CR, Glenn GM. Transcutaneous immunization with bacterial ADP-ribosylating exotoxins, subunits, and unrelated adjuvants. Infect. Immun. 68(9), 5306-5313 (2000).
    • (2000) Infect. Immun , vol.68 , Issue.9 , pp. 5306-5313
    • Scharton-Kersten, T.1    Yu, J.2    Vassell, R.3    O'Hagan, D.4    Alving, C.R.5    Glenn, G.M.6
  • 48
    • 0028985871 scopus 로고
    • Dissociation of Escherichia coli heat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity
    • Dickinson BL, Clements JD. Dissociation of Escherichia coli heat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity. Infect. Immun. 63(5), 1617-1623 (1995).
    • (1995) Infect. Immun , vol.63 , Issue.5 , pp. 1617-1623
    • Dickinson, B.L.1    Clements, J.D.2
  • 50
    • 0033000163 scopus 로고    scopus 로고
    • Oral immunization with urease and Escherichia coli heat-labile enterotoxin is safe and immunogenic in Helicobacter pylori-infected adults
    • Michetti P, Kreiss C, Kotloff KL et al. Oral immunization with urease and Escherichia coli heat-labile enterotoxin is safe and immunogenic in Helicobacter pylori-infected adults. Gastroenterology 116(4), 804-812 (1999).
    • (1999) Gastroenterology , vol.116 , Issue.4 , pp. 804-812
    • Michetti, P.1    Kreiss, C.2    Kotloff, K.L.3
  • 51
    • 0029493562 scopus 로고
    • The mucosal adjuvant activities of ADP-ribosylating bacterial enterotoxins
    • Snider DP. The mucosal adjuvant activities of ADP-ribosylating bacterial enterotoxins. Crit. Rev. Immunol. 15(3-4), 317-348 (1995).
    • (1995) Crit. Rev. Immunol , vol.15 , Issue.3-4 , pp. 317-348
    • Snider, D.P.1
  • 52
    • 0034058064 scopus 로고    scopus 로고
    • Parenteral adjuvant activities of Escherichia coli heat-labile toxin and its B subunit for immunization of mice against gastric Helicobacter pylori infection
    • Weltzin R, Guy B, Thomas WD Jr, Giannasca PJ, Monath TP. Parenteral adjuvant activities of Escherichia coli heat-labile toxin and its B subunit for immunization of mice against gastric Helicobacter pylori infection. Infect. Immun. 68(5), 2775-2782 (2000).
    • (2000) Infect. Immun , vol.68 , Issue.5 , pp. 2775-2782
    • Weltzin, R.1    Guy, B.2    Thomas Jr, W.D.3    Giannasca, P.J.4    Monath, T.P.5
  • 54
    • 0031567923 scopus 로고    scopus 로고
    • Intranasal immunization with CTL epitope peptides from HIV-1 or ovalbumin and the mucosal adjuvant cholera toxin induces peptide-specific CTLs and protection against tumor development in vivo
    • Porgador A, Staats HF, Faiola B, Gilboa E, Palker TJ. Intranasal immunization with CTL epitope peptides from HIV-1 or ovalbumin and the mucosal adjuvant cholera toxin induces peptide-specific CTLs and protection against tumor development in vivo. J. Immunol. 158(2), 834-841 (1997).
    • (1997) J. Immunol , vol.158 , Issue.2 , pp. 834-841
    • Porgador, A.1    Staats, H.F.2    Faiola, B.3    Gilboa, E.4    Palker, T.J.5
  • 55
    • 0034602670 scopus 로고    scopus 로고
    • Percutaneous peptide immunization via corneum barrier-disrupted murine skin for experimental tumor immunoprophylaxis
    • Seo N, Tokura Y, Nishijima T, Hashizume H, Furukawa F, Takigawa M. Percutaneous peptide immunization via corneum barrier-disrupted murine skin for experimental tumor immunoprophylaxis. Proc. Natl Acad. Sci. USA 97(1), 371-376 (2000).
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , Issue.1 , pp. 371-376
    • Seo, N.1    Tokura, Y.2    Nishijima, T.3    Hashizume, H.4    Furukawa, F.5    Takigawa, M.6
  • 56
    • 0021058990 scopus 로고
    • New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development
    • Levine MM, Kaper JB, Black RE, Clements ML. New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development. Microbiol. Rev. 47(4), 510-550 (1983).
    • (1983) Microbiol. Rev , vol.47 , Issue.4 , pp. 510-550
    • Levine, M.M.1    Kaper, J.B.2    Black, R.E.3    Clements, M.L.4
  • 57
    • 28844462706 scopus 로고    scopus 로고
    • Transcutaneous immunization in mice: Induction of T-helper and cytotoxic T lymphocyte responses and protection against human papillomavirus-induced tumors
    • Dell K, Koesters R, Gissmann L. Transcutaneous immunization in mice: induction of T-helper and cytotoxic T lymphocyte responses and protection against human papillomavirus-induced tumors. Int. J. Cancer 118(2), 364-372 (2005).
    • (2005) Int. J. Cancer , vol.118 , Issue.2 , pp. 364-372
    • Dell, K.1    Koesters, R.2    Gissmann, L.3
  • 58
    • 24144494203 scopus 로고    scopus 로고
    • Transcutaneous immunization with cytotoxic T-cell peptide epitopes provides effective antitumor immunity in mice
    • Itoh T, Celis E. Transcutaneous immunization with cytotoxic T-cell peptide epitopes provides effective antitumor immunity in mice. J. Immunother. 28(5), 430-437 (2005).
    • (2005) J. Immunother , vol.28 , Issue.5 , pp. 430-437
    • Itoh, T.1    Celis, E.2
  • 59
    • 2342447405 scopus 로고    scopus 로고
    • Epicutaneous application of CpG oligodeoxynucleotides with peptide or protein antigen promotes the generation of CTL
    • Klimuk SK, Najar HM, Semple SC, Aslanian S, Dutz JP. Epicutaneous application of CpG oligodeoxynucleotides with peptide or protein antigen promotes the generation of CTL. J. Invest. Dermatol. 122(4), 1042-1049 (2004).
    • (2004) J. Invest. Dermatol , vol.122 , Issue.4 , pp. 1042-1049
    • Klimuk, S.K.1    Najar, H.M.2    Semple, S.C.3    Aslanian, S.4    Dutz, J.P.5
  • 60
    • 14044265101 scopus 로고    scopus 로고
    • Priming of CTL by transcutaneous peptide immunization with imiquimod
    • Rechtsteiner G, Warger T, Osterloh P, Schild H, Radsak MP. Priming of CTL by transcutaneous peptide immunization with imiquimod. J. Immunol. 174(5), 2476-2480 (2005).
    • (2005) J. Immunol , vol.174 , Issue.5 , pp. 2476-2480
    • Rechtsteiner, G.1    Warger, T.2    Osterloh, P.3    Schild, H.4    Radsak, M.P.5
  • 61
    • 33646447036 scopus 로고    scopus 로고
    • Phase I evaluation of intranasal trivalent inactivated influenza vaccine with nontoxigenic Escherichia coli enterotoxin and novel biovector as mucosal adjuvants, using adult volunteers
    • Stephenson I, Zambon MC, Rudin A et al. Phase I evaluation of intranasal trivalent inactivated influenza vaccine with nontoxigenic Escherichia coli enterotoxin and novel biovector as mucosal adjuvants, using adult volunteers. J. Virol. 80(10), 4962-4970 (2006).
    • (2006) J. Virol , vol.80 , Issue.10 , pp. 4962-4970
    • Stephenson, I.1    Zambon, M.C.2    Rudin, A.3
  • 62
    • 0035010023 scopus 로고    scopus 로고
    • Safety and immunogenicity of oral inactivated whole-cell Helicobacter pylori vaccine with adjuvant among volunteers with or without subclinical infection
    • Kotloff KL, Sztein MB, Wasserman SS, Losonsky GA, DiLorenzo SC, Walker RI. Safety and immunogenicity of oral inactivated whole-cell Helicobacter pylori vaccine with adjuvant among volunteers with or without subclinical infection. Infect. Immun. 69(6), 3581-3590 (2001).
    • (2001) Infect. Immun , vol.69 , Issue.6 , pp. 3581-3590
    • Kotloff, K.L.1    Sztein, M.B.2    Wasserman, S.S.3    Losonsky, G.A.4    DiLorenzo, S.C.5    Walker, R.I.6
  • 63
    • 10444228872 scopus 로고    scopus 로고
    • Improved immune responses to influenza vaccination in the elderly using an immunostimulant patch
    • Frech SA, Kenney RT, Spyr CA, Lazar H, Glück R, Glenn GM. Improved immune responses to influenza vaccination in the elderly using an immunostimulant patch. Vaccine 23(7), 946-950 (2005).
    • (2005) Vaccine , vol.23 , Issue.7 , pp. 946-950
    • Frech, S.A.1    Kenney, R.T.2    Spyr, C.A.3    Lazar, H.4    Glück, R.5    Glenn, G.M.6
  • 64
    • 0033009744 scopus 로고    scopus 로고
    • Transcutaneous immunization with bacterial ADP-ribosylating exotoxins as antigens and adjuvants
    • Glenn GM, Scharton-Kersten T, Vassell R, Matyas GR, Alving CR. Transcutaneous immunization with bacterial ADP-ribosylating exotoxins as antigens and adjuvants. Infect. Immun. 67(3), 1100-1106 (1999).
    • (1999) Infect. Immun , vol.67 , Issue.3 , pp. 1100-1106
    • Glenn, G.M.1    Scharton-Kersten, T.2    Vassell, R.3    Matyas, G.R.4    Alving, C.R.5
  • 65
    • 0034666482 scopus 로고    scopus 로고
    • Transcutaneous immunization of domestic animals: Opportunities and challenges
    • Hammond SA, Tsonis C, Sellins K et al. Transcutaneous immunization of domestic animals: opportunities and challenges. Adv. Drug Deliv. Rev. 43, 45-55 (2000).
    • (2000) Adv. Drug Deliv. Rev , vol.43 , pp. 45-55
    • Hammond, S.A.1    Tsonis, C.2    Sellins, K.3
  • 66
    • 33746848966 scopus 로고    scopus 로고
    • Transcutaneous immunization with inactivated influenza virus induces protective immune responses
    • Skountzou I, Quan FS, Jacob J, Compans RW, Kang SM. Transcutaneous immunization with inactivated influenza virus induces protective immune responses. Vaccine 24(35-36), 6110-6119 (2006).
    • (2006) Vaccine , vol.24 , Issue.35-36 , pp. 6110-6119
    • Skountzou, I.1    Quan, F.S.2    Jacob, J.3    Compans, R.W.4    Kang, S.M.5
  • 67
    • 35349025777 scopus 로고    scopus 로고
    • Glenn GM. Advanced development of antigen sparing pandemic influenza vaccines. Department of Health and Human Services Contract No. HHSO100200700031C, Washington DC, USA (2007).
    • Glenn GM. Advanced development of antigen sparing pandemic influenza vaccines. Department of Health and Human Services Contract No. HHSO100200700031C, Washington DC, USA (2007).
  • 68
    • 33645399959 scopus 로고    scopus 로고
    • Safety and immunogenicity of an inactivated subvirion influenza A (H5N1) vaccine
    • Treanor JJ, Campbell JD, Zangwill KM, Rowe T, Wolff M. Safety and immunogenicity of an inactivated subvirion influenza A (H5N1) vaccine. N. Engl. J. Med. 354(13), 1343-1351 (2006).
    • (2006) N. Engl. J. Med , vol.354 , Issue.13 , pp. 1343-1351
    • Treanor, J.J.1    Campbell, J.D.2    Zangwill, K.M.3    Rowe, T.4    Wolff, M.5
  • 69
    • 17844386838 scopus 로고    scopus 로고
    • Vaccination against enterotoxigenic Escherichia coli, a cause of travelers' diarrhea
    • Steffen R, Castelli F, Dieter Nothdurft H, Rombo L, Jane Zuckerman N. Vaccination against enterotoxigenic Escherichia coli, a cause of travelers' diarrhea. J. Travel Med. 12(2), 102-107 (2005).
    • (2005) J. Travel Med , vol.12 , Issue.2 , pp. 102-107
    • Steffen, R.1    Castelli, F.2    Dieter Nothdurft, H.3    Rombo, L.4    Jane Zuckerman, N.5
  • 70
    • 0032184817 scopus 로고    scopus 로고
    • Transcutaneous immunization with cholera toxin protects mice against lethal mucosal toxin challenge
    • Glenn GM, Scharton-Kersten T, Vassell R, Mallett CP, Hale TL, Alving CR. Transcutaneous immunization with cholera toxin protects mice against lethal mucosal toxin challenge. J. Immunol. 161(7), 3211-3214 (1998).
    • (1998) J. Immunol , vol.161 , Issue.7 , pp. 3211-3214
    • Glenn, G.M.1    Scharton-Kersten, T.2    Vassell, R.3    Mallett, C.P.4    Hale, T.L.5    Alving, C.R.6
  • 71
    • 35348993578 scopus 로고    scopus 로고
    • Transcutaneous immunization with the heat labile toxin (LT) of enterotoxigenic Escherichia coli (ETEC) protects in a Phase II field trial in travelers to Guatemala (GU) and Mexico (MX)
    • Presented at:, Chicago, IL, USA, September 17-20, Abstract 3810
    • Glenn G, Frech S, Villar C et al. Transcutaneous immunization with the heat labile toxin (LT) of enterotoxigenic Escherichia coli (ETEC) protects in a Phase II field trial in travelers to Guatemala (GU) and Mexico (MX). Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, IL, USA, September 17-20, 2007 (Abstract 3810).
    • (2007) 47th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Glenn, G.1    Frech, S.2    Villar, C.3
  • 72
    • 34548677712 scopus 로고    scopus 로고
    • Adjuvant for transcutaneous immunization
    • US5980898. The United States of America as represented by the US Army Medical Research & Material Command, Washington, DC, USA 1999
    • Glenn GM, Alving CR. Adjuvant for transcutaneous immunization. US5980898. The United States of America as represented by the US Army Medical Research & Material Command, Washington, DC, USA (1999).
    • Glenn, G.M.1    Alving, C.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.