Memory retrieval improvement by Heteropterys aphrodisiaca in aging rats

Brazilian Journal of Pharmaceutical Sciences

Volumn 47, Issue 4, 2011, Pages 825-832

  Galvão, Suzana Maria Pereira ^a   Mendes, Fúlvio Rieli ^b   Oliveira, Maria Gabriela Menezes de ^c   Mattei, Rita ^c   Mello, João Carlos Palazzo de ^d   Roman Júnior, Walter Antonio ^e   Carlini, Elisaldo de Araújo ^c  

^a UNIVERSIDADE ESTADUAL DO PIAUÍ   (Brazil)

^b UNIVERSIDADE FEDERAL DO ABC   (Brazil)

^c FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^d STATE UNIVERSITY OF MARINGÁ   (Brazil)

^e Universidade Comunitaria Regional de Chapeco   (Brazil)

Author keywords

Antioxidants; Flavonoids; Heteropterys aphrodisiaca O; Mach antioxidant activity; Mach pharmacognosy; Malpighiaceae pharmacognosy; Plant extract

Indexed keywords

ASTILBIN; BST 0298; FLAVONOID; HETEROPTERYS APHRODISIACA EXTRACT; ISOASTILBIN; MALONALDEHYDE; NEOASTILBIN; PLANT EXTRACT; SCOPOLAMINE; UNCLASSIFIED DRUG;

AGING; AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG ISOLATION; DRUG STRUCTURE; HETEROPTERYS APHRODISIACA; IN VITRO STUDY; LEARNING; LIPID PEROXIDATION; MALPIGHIACEAE; MAZE TEST; MEMORY; NONHUMAN; PASSIVE AVOIDANCE; PLANT ROOT; RAT; REPEATED DRUG DOSE; SOLVENT EXTRACTION; TASK PERFORMANCE; TREATMENT DURATION;

EID: 84859205244     PISSN: 19848250     EISSN: 21759790     Source Type: Journal    
DOI: 10.1590/S1984-82502011000400020     Document Type: Article

References (30)

1. CALABRESE, V.; CORNELIUS, C.; DINKOVA-KOSTOVA, A.T.; CALABRESE, E.J.; MATTSON, M.P. Cellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders. Antioxid. Redox Signal., v.13, n.11, p.1763-1811, 2010.
2. DE LA MORENA, G.S.; PÉREZ, J.M. Efecto hepatoprotector inducido por el flavonoide astilbina frente a un modelo animal tratado con tetracloruro de carbono. Rev. Cubana Plant. Med., v.1, n.1, p.36-39, 1999.
3. ESPÍNOLA, E.B.; OLIVEIRA, M.G.M.; CARLINI, E.A. Differences in central and peripheral responses to oxotremorine in young and aged rats. Pharmacol. Biochem. Behav., v.62, n.3, p.419-423, 1999.
4. GALVÃO, S.M.P.; MARQUES, L.C.; OLIVEIRA, M.G.M.; CARLINI, E.A. Heteropterys aphrodisiaca (extract BST0298): a Brazilian plant that improves memory deficits in old rats. J. Ethnopharmacol., v.79, n.3, p.305-311, 2002.
5. GALVÃO, S.M.P. Estudos farmacológicos e toxicológicos de Heteropteris aphrodisiaca O. Mach. - Malpighiaceae (nó-de-cachorro) em roedores jovens e idosos. São Paulo, 1997. 163 p. [Dissertation of Máster degree. Federal University of São Paulo].
6. HASSELMO, M.E. The role of acetylcholine in learning and memory. Curr. Opin. Neurobiol., v.16, n.6, p.710-715, 2006.
7. HEO, H.J.; SUH, Y.M.; KIM, M.J.; CHOI, S.J.; MUN, N.S.; KIM, H.K.; KIM, E.; KIM, C.J.; CHO, H.Y.; KIM, Y.J.; SHIN, D.H. Daidzein activates choline acetyltransferase from MC-IXC cells and improves drug-induced amnesia. Biosci. Biotechnol. Biochem., v.70, n.1, p.107-111, 2006.
8. HSIEH, M.T.; PENG, W.H.; WU, C.R.; WANG, W.H. The ameliorating effects of the cognitive-enhancing Chinese herbs on scopolamine-induced amnesia in rats. Phytother. Res., v.14, n.5, p.375-377, 2000.
9. KARTNIG, T.; WEGSCHAIDER, O. Possible identification of sugars from small amounts of glycosides or sugar mixtures. J. Chromatogr. A, v.61, n.2, p.375-376, 1971.
10. LEE, S.C.; MOON, Y.S.; YOU, K.H. Effects of red gingeng saponins and nootropic drugs on impaired acquisition of ethanol-treated rats in passive avoidance performance. J. Ethnopharmacol., v.69, n.1, p.1-8, 2000.
11. MARQUES, L.C.; PIERRE, C.; ROMAN-JÚNIOR, W.A.; CARDOSO, M.L.C.; MILANEZE-GUTIERRE, M.A.; MELLO, J.C.P. Controle farmacognóstico das raízes de Heteropterys aphrodisiaca O. Mach. (Malpiguiaceae). Rev. Bras. Farmacog., v.17, n.4, p.604-615, 2007.
12. MATTEI, R.; BARROS, M.P.; GALVÃO, S.M.P.; BECHARA, E.J.H.; CARLINI, E.A. Heteropterys aphrodisiaca O. Machado: effects of extract BST0298 on the oxidative stress of young and old rat brains. Phytother. Res., v.15, n.7, p.604-607, 2001.
13. MATTEI, R.; POLOTOW, G.T.; VARDARIS, C.V.; GUERRA, B.A.; LEITE, J.R.; OTTON, R.; BARROS, P.M. Astaxanthin limits fish oil-related oxidative insult in the anterior forebrain of Wistar rats: putative anxiolytic effects? Pharmacol. Biochem. Behav., v.99, n.3, p.349-355, 2011.
14. MENDES, F.R.; CARLINI, E.A. Brazilian plants as possible adaptogens: an ethnopharmacological survey of books edited in Brazil. J. Ethnopharmacol., v.109, n.3, p.493-500, 2007.
15. MERLINI, L.; PINZA, M. Trends in searching for new cognition enhancing drugs. Prog. Neuropsychopharmacol. Biol. Psychiatry., v.13, suppl., p.S61-S75, 1989.
16. MIRANDA, M.I.; FERREIRA, G.; RAMIREZ-LUGO, L.; BERMÚDEZ-RATTONI, F. Role of cholinergic system on the construction of memories: taste memory encoding. Neurobiol. Learn. Mem., v.80, n.3, p.211-222, 2003.
17. MOOSMANN, B.; BEHL C. Antioxidants as treatment for neurodegenerative disorders. Expert. Opin. Investig. Drugs, v.11, n.10, p.1407-1435, 2002.
18. MUKHERJEE, P.K.; KUMAR, V.; MAL, M.; HOUGHTON, P.J. Acetylcholinesterase inhibitors from plants. Phytomedicine, v.14, n.4, p.289-300, 2007.
19. NG, T.B.; LIU, F.; WANG, Z.T. Antioxidative activity of natural products from plants. Life Sci., v.66, n.8, p.709-723, 2000.
20. NITTA, H.; MATSUMOTO, K.; SHIMIZU, M.; NI, X.H.; WATANABE, H. Panax ginseng extract improves the performance of aged fischer 344 rats in radial maze task but not in operant brightness discrimination task. Biol. Pharm. Bull., v.18, n.9, p.1286-1288, 1995.
21. PACKER, L.; HIRAMATSU, M.; YOSHIKAWA, T. Antioxidant food supplements in human health. San Diego: Academic Press, 1999. 511 p.
22. PERNECZKY, R.; KURZ, A. Current antidementive therapy. MMW Fortschr. Med., v.146, n.2 (spec.), p.53-56, 2004.
23. PETACCI, F.; FREITAS, S.S.; BRUNETTI, I.L.; KHALIL, N.M. Inhinbition of peroxidase activity and scavenging of reactive oxygen species by astilbin isolated from Dimorphandra mollis (Fabaceae, Caesalpinioideae). Biol. Res., v.43, n.1, p.63-74, 2010.
24. PETKOV, V.D.; BELCHEVA, S.; PETKOV, V.V. Behavioral effects of Ginkgo biloba L., Panax ginseng C.A. Mey. and Gincosan. Am. J. Chin. Med., v.31, n.6, p.841-855, 2003.
25. POTT, A.; POTT, V.J. Plantas do Pantanal. Corumbá: EMBRAPA - SPI, 1994. p.101.
26. QUIRARTE, G.L.; CRUZ-MORALES, S.E.; CEPEDA, A.; GARCIA-MONTAÑEZ, M.; ROLDÁN-ROLDÁN, G.; PRADO-ALCALÁ, R.A. Effects of central muscarinic blockade on passive avoidance: anterograde amnesia, state dependency, or both? Behav. Neural Biol., v.62, n.1, p.15-20, 1994.
27. ROMAN JÚNIOR, W.A.; CARDOSO, M.L.C.; VILEGAS, W.; NAKAMURA, C.V.; DIAS FILHO, B.P.; MELLO, J.C.P. 2,3,4,6-tetra-O-(3-nitropropanoyl)-O-β-D-glucopyranoside, a new antimicrobial from the roots of Heteropteris aphrodisiaca. Acta Farm. Bonaerense, v.24, n.4, p.543-545, 2005.
28. ROMAN JÚNIOR, W.A. Identificação de nitrocomposto e di-hidroflavonóis, atividades antibacteriana, antifúngica e antiviral de substâncias isoladas dos extratos liofilizados das raízes de Heteropteris aphrodisiaca O. Mach., Malpighiaceae, nó-de-cachorro. Araraquara, 2003. 132 p. [Dissertation of Máster degree. State University of São Paulo "Júlio de Mesquita Filho"].
29. STOCKS, J.; GUTTERIDGE, J.M.C.; SHARP, J.; DORMANDY, T.L. Assay using brain homogenates for measuring the antioxidant activity of biological fluids. Clin. Sci. Mol. Med., v.47, n.3, p.215-222, 1974.
30. VOIGT, R. Pharmazeutische technologie. 7.ed. Berlin: Ullstein Mosby, 1993. p.496-504.