Marburg virus glycoprotein GP2: PH-dependent stability of the ectodomain α-helical bundle

Biochemistry

Volumn 51, Issue 12, 2012, Pages 2515-2525

  Harrison, Joseph S ^a   Koellhoffer, Jayne F ^a   Chandran, Kartik ^a   Lai, Jonathan R ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTICAL ULTRACENTRIFUGATION; BIOPHYSICAL PROPERTIES; CONFORMATIONAL PREFERENCES; DRIVING FORCES; EBOLA VIRUS; ECTODOMAIN; ENDOSOMES; ENVELOPE GLYCOPROTEINS; ENVELOPED VIRUS; ENVIRONMENTAL CONDITIONS; GLUTAMIC ACID RESIDUES; HELICAL BUNDLE; HELICAL CONFORMATION; HELICAL STRUCTURES; HOST CELLS; MEMBRANE FUSION; MUTATIONAL ANALYSIS; PH-DEPENDENT; REFOLDING; TRANSMEMBRANES;

AMINO ACIDS; ANOXIC SEDIMENTS; CELL MEMBRANES; CENTRIFUGATION; ESCHERICHIA COLI; GLYCOPROTEINS; MACHINERY; OLIGOMERS; STABILITY;

VIRUSES;

GLUTAMIC ACID; GLYCOPROTEIN GP 2; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ALPHA HELIX; ARTICLE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; ENDOSOME; ESCHERICHIA COLI; MARBURG VIRUS; MELTING POINT; MOLECULAR WEIGHT; MUTATIONAL ANALYSIS; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN DENATURATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STABILITY; SEDIMENTATION; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; THERMODYNAMICS; ULTRACENTRIFUGATION;

AMINO ACID SEQUENCE; GLYCOPROTEINS; HYDROGEN-ION CONCENTRATION; MARBURGVIRUS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; VIRAL ENVELOPE PROTEINS; VIRUS INTERNALIZATION;

EBOLA VIRUS; ESCHERICHIA COLI; FILOVIRIDAE; LAKE VICTORIA MARBURGVIRUS;

EID: 84859180550     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi3000353     Document Type: Article

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