Cardiomyopathic Tropomyosin Mutations that Increase Thin Filament Ca 2+ Sensitivity and Tropomyosin N-domain Flexibility

Journal of Biological Chemistry

Volumn 278, Issue 43, 2003, Pages 41742-41748

  Heller, Mark J ^a   Nili, Mahta ^b   Homsher, Earl ^b   Tobacman, Larry S ^a,c  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; FREE ENERGY; MUTAGENESIS; THERMODYNAMIC STABILITY;

MUTATIONS;

PROTEINS;

ACTIN; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE; MUTANT PROTEIN; MYOSIN SUBFRAGMENT 1; TROPOMYOSIN; TROPONIN;

ARTICLE; BINDING SITE; CALCIUM BINDING; CIRCULAR DICHROISM; ENERGY; FAMILIAL HYPERTROPHIC CARDIOMYOPATHY; MELTING POINT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; THERMOSTABILITY; THIN FILAMENT;

ADENOSINE TRIPHOSPHATASES; ANIMALS; CALCIUM; CARDIOMYOPATHIES; CATTLE; KINETICS; MICROFILAMENTS; MUTATION; PROTEIN DENATURATION; PROTEIN STRUCTURE, TERTIARY; RABBITS; RATS; TEMPERATURE; THERMODYNAMICS; TROPOMYOSIN;

EID: 0142149180     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M303408200     Document Type: Article

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