Optimal mechanical environment of the healing bone fracture/osteotomy

International Orthopaedics

Volumn 36, Issue 4, 2012, Pages 689-695

  Mavčič, Blaž ^a   Antolič, Vane ^a  

^a UNIVERSITY MEDICAL CENTRE LJUBLJANA   (Slovenia)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMECHANICS; BONE MASS; BONE REMODELING; CALLUS; COMPRESSION OSTEOSYNTHESIS; COMPRESSIVE STRENGTH; FEEDBACK SYSTEM; FRACTURE HEALING; HUMAN; IMMOBILIZATION; INTRACELLULAR SIGNALING; INTRAMEDULLARY NAILING; LOADING TEST; MORPHOLOGICAL ADAPTATION; NONHUMAN; OSTEOLYSIS; OSTEOTOMY; PRACTICE GUIDELINE; PRIORITY JOURNAL; RESISTANCE TRAINING; REVIEW; STIMULUS RESPONSE; STRESS STRAIN RELATIONSHIP; WEIGHT BEARING;

ADAPTATION, PHYSIOLOGICAL; FRACTURE FIXATION; FRACTURE HEALING; FRACTURES, BONE; HUMANS; MECHANOTRANSDUCTION, CELLULAR; OSTEOCYTES; OSTEOTOMY; STRESS, MECHANICAL; WEIGHT-BEARING;

EID: 84859157601     PISSN: 03412695     EISSN: 14325195     Source Type: Journal    
DOI: 10.1007/s00264-012-1487-8     Document Type: Review

References (49)

1. Wood GW (2007) Fractures and dislocation, general principles of fracture treatment. In: Canale ST, Beaty JH (eds) Campbell's operative orthopaedics, 11th edn. Mosby, Philadelphia, pp 3018-3085
2. Rüedi TP, Buckley RE, Moran CG (2007) AO principles of fracture management. Thieme, New York
3. Wolff J (2011) The classic: on the significance of the architecture of the spongy substance for the question of bone growth: a preliminary publication. 1869. Clin Orthop Relat Res 469:3077-3078. doi:10.1007/s11999-011-2041-5
4. Lanyon LE (1974) Experimental support for the trajectorial theory of bone structure. J Bone Joint Surg Br 56:160-166
5. Lanyon LE, Baggott DG (1976) Mechanical function as an influence on the structure and form of bone. J Bone Joint Surg Br 58-B:436-443
6. Woo SL, Kuei SC, Amiel D, Gomez MA, Hayes WC, White FC, Akeson WH (1981) The effect of prolonged physical training on the properties of long bone: a study of Wolff's Law. J Bone Joint Surg Am 63:780-787 (Pubitemid 11127663)
7. McKibbin B (1978) The biology of fracture healing in long bones. J Bone Joint Surg Br 60-B:150-162
8. Baggott DG, Goodship AE, Lanyon LE (1981) A quantitative assessment of compression plate fixation in vivo: an experimental study using the sheep radius. J Biomech 14:701-711 (Pubitemid 12248248)
9. Chao EY, Kasman RA, An KN (1982) Rigidity and stress analyses of external fracture fixation devices - a theoretical approach. J Biomech 15:971-983
10. Lewallen DG, Chao EY, Kasman RA, Kelly PJ (1984) Comparison of the effects of compression plates and external fixators on early bone-healing. J Bone Joint Surg Am 66:1084-1091 (Pubitemid 14011466)
11. Terjesen T (1984) Bone healing after metal plate fixation and external fixation of the osteotomized rabbit tibia. Acta Orthop Scand 55:69-77
12. Cheal EJ, Hayes WC, White AA 3rd, Perren SM (1985) Stress analysis of compression plate fixation and its effects on long bone remodeling. J Biomech 18:141-150 (Pubitemid 15142455)
13. Court-Brown CM (1985) The effect of external skeletal fixation on bone healing and bone blood supply. An experimental study. Clin Orthop Relat Res 201:278-289
14. Hart MB, Wu JJ, Chao EY, Kelly PJ (1985) External skeletal fixation of canine tibial osteotomies. Compression compared with no compression. J Bone Joint Surg Am 67:598-605 (Pubitemid 15087602)
15. Holmström T, Paavolainen P, Slätis P, Karaharju E (1986) Effect of compression on fracture healing. Plate fixation studied in rabbits. Acta Orthop Scand 57:368-372
16. De Bastiani G, Aldegheri R, Renzi Brivio L (1986) Dynamic axial fixation. A rational alternative for the external fixation of fractures. Int Orthop 10:95-99
17. Aalto K, Holmström T, Karaharju E, Joukainen J, Paavolainen P, Slätis P (1987) Fracture repair during external fixation. Torsion tests of rabbit osteotomies. Acta Orthop Scand 58:66-70
18. Kunnamo I (2005) Evidence-based medicine guidelines. Wiley, Chichester
19. Handoll HH, Parker MJ, Sherrington C (2003) Mobilisation strategies after hip fracture surgery in adults. Cochrane Database Syst Rev 1:CD001704
20. Skerry TM (2008) The response of bone to mechanical loading and disuse: fundamental principles and influences on osteoblast/osteocyte homeostasis. Arch Biochem Biophys 473:117-123
21. Marino AA, Becker RO (1970) Piezoelectric effect and growth control in bone. Nature 228:473-474. doi:10.1038/228473a0
22. Ciombor DM, Aaron RK (2005) The role of electrical stimulation in bone repair. Foot Ankle Clin 10:579-593 (Pubitemid 41627809)
23. Frost HM (2004) A 2003 update of bone physiology and Wolff's Law for clinicians. Angle Orthod 74:3-15
24. Ehrlich PJ, Lanyon LE (2002) Mechanical strain and bone cell function: a review. Osteoporos Int 13:688-700 (Pubitemid 35000996)
25. Liedert A, Kaspar D, Augat P, Ignatius A, Claes L (2005) Mechanobiology of bone tissue and bone cells. In: Kamkin A, Kiseleva I (eds) Mechanosensitivity in cells and tissues. Academia, Moscow
26. Lee K, Jessop H, Suswillo R, Zaman G, Lanyon L (2003) Bone adaptation requires oestrogen receptor-alpha. Nature 424:389 (Pubitemid 36917478)
27. Sutherland MK, Hui DU, Rao LG, Wylie JN, Murray TM (1996) Immunohistochemical localization of the estrogen receptor in human osteoblastic SaOS-2 cells: association of receptor levels with alkaline phosphatase activity. Bone 18:361-369 (Pubitemid 26149349)
28. Sawakami K, Robling AG, Ai M, Pitner ND, Liu D, Warden SJ, Li J, Maye P, Rowe DW, Duncan RL, Warman ML, Turner CH (2006) The Wnt co-receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment. J Biol Chem 281:23698-23711 (Pubitemid 44274145)
29. Saxon LK, Jackson BF, Sugiyama T, Lanyon LE, Price JS (2011) Analysis of multiple bone responses to graded strains above functional levels, and to disuse, in mice in vivo show that the human Lrp5 G171V high bone mass mutation increases the osteogenic response to loading but that lack of Lrp5 activity reduces it. Bone 49:184-193
30. Jee WSS (2001) Integrated bone tissue physiology: anatomy and physiology. In: Cowin SC (ed) Bone mechanics handbook, 2nd edn. CRC, Boca Raton, pp 1-68
31. Meyer U, Meyer T, Wiesmann HP (1999) The effect of magnitude and frequency of interfragmentary strain on the tissue response to distraction osteogenesis. J Oral Maxillofac Surg 57:1331-1339
32. Frost HM, Meyer U, Joos U, Jensen OT (2002) Dental alveolar distraction osteogenesis and the Utah paradigm. In: Jensen OT (ed) Alveolar distraction osteogenesis. Quintessence, Carol Stream, pp 1-16
33. Fritton SP, Rubin CT (2001) In vivo measurement of bone deformations using strain gauges. In: Cowin SC (ed) Bone mechanics handbook, 2nd edn. CRC, Boca Raton, pp 8-34
34. Rubin CT, Turner AS, Bain S, Mallinckrodt C, McLeod K (2001) Anabolism. Low mechanical signals strengthen long bones. Nature 412:603-604
35. Rubin CT, Xu G, Judex S (2001) The anabolic activity of bone tissue, suppressed by disuse, is normalized by brief exposure to extremely low-magnitude mechanical stimuli. FASEB J 15:2225-2229 (Pubitemid 32927940)
36. Rubin CT, Turner AS, Müller R, Mittra E, McLeod K, Lin W, Qin YX (2002) Quantity and quality of trabecular bone in the femur are enhanced by a strongly anabolic, noninvasive mechanical intervention. J Bone Miner Res 17:349-357 (Pubitemid 34087668)
37. Churches AE, Howlett CR, Waldron KJ, Ward GW (1979) The response of living bone to controlled time-varying loading: method and preliminary results. J Biomech 12:35-45 (Pubitemid 9104301)
38. Lanyon LE, Paul IL, Rubin CT, Thrasher EL, DeLaura R, Rose RM, Radin EL (1981) In vivo strain measurements from bone and prosthesis following total hip replacement. An experimental study in sheep. J Bone Joint Surg Am 63:989-1001
39. Churches AE, Howlett CR (1982) Functional adaptation of bone in response to sinusoidally varying controlled compressive loading of the ovine metacarpus. Clin Orthop Relat Res 168:265-280 (Pubitemid 12044180)
40. O'Connor JA, Lanyon LE, MacFie H (1982) The influence of strain rate on adaptive bone remodelling. J Biomech 15:767-781 (Pubitemid 13178607)
41. Rubin CT, Lanyon LE (1984) Regulation of bone formation by applied dynamic loads. J Bone Joint Surg Am 66:397-402 (Pubitemid 14169460)
42. Lanyon LE, Rubin CT (1984) Static vs dynamic loads as an influence on bone remodelling. J Biomech 17:897-905 (Pubitemid 15166456)
43. Rubin CT, Lanyon LE (1985) Regulation of bone mass by mechanical strain magnitude. Calcif Tissue Int 37:411-417 (Pubitemid 15015324)
44. Lanyon LE, Rubin CT, Baust G (1986) Modulation of bone loss during calcium insufficiency by controlled dynamic loading. Calcif Tissue Int 38:209-216 (Pubitemid 16137013)
45. Panjabi MM, White AA 3rd, Wolf JW Jr (1979) A biomechanical comparison of the effects of constant and cyclic compression on fracture healing in rabbit long bones. Acta Orthop Scand 50:653-661 (Pubitemid 10162507)
46. Wolf JW Jr, White AA 3rd, Panjabi MM, Southwick WO (1981) Comparison of cyclic loading versus constant compression in the treatment of long-bone fractures in rabbits. J Bone Joint Surg Am 63:805-810 (Pubitemid 11127666)
47. Carter DR (1984) Mechanical loading histories and cortical bone remodeling. Calcif Tissue Int 36(Suppl):S19-S24
48. Kempf I, Leung K, Grosse A (2002) Practice of intramedullary locked nails: scientific basis and standard techniques. Springer, Berlin, pp 47-48
49. Judex S, Rubin CT (2010) Is bone formation induced by high-frequency mechanical signals modulated by muscle activity? J Musculoskelet Neuronal Interact 10:3-11