RNA sensors enable human mast cell anti-viral chemokine production and IFN-mediated protection in response to antibody-enhanced dengue virus infection

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Brown, Michael G ^a,b   McAlpine, Sarah M ^a   Huang, Yan Y ^a,b   Haidl, Ian D ^a   Al Afif, Ayham ^a,b   Marshall, Jean S ^a   Anderson, Robert ^a,b  

^a DALHOUSIE UNIVERSITY   (Canada)

^b IWK HEALTH CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISERUM; CHEMOKINE; DSRNA DEPENDENT PROTEIN KINASE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERFERON; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MELANOMA DIFFERENTIATION ASSOCIATED PROTEIN 5; MESSENGER RNA; PATTERN RECOGNITION RECEPTOR; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN; PROTEIN KINASE; RANTES; RETINOIC ACID INDUCIBLE PROTEIN I; UNCLASSIFIED DRUG; ANTIBODY; ANTIVIRUS AGENT; RNA; SMALL INTERFERING RNA;

ANTIBODY ENHANCED DENGUE VIRUS INFECTION; ARTICLE; CELL LINE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENGUE; DENGUE VIRUS; GENE CONTROL; HOMEOSTASIS; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; INFECTION SENSITIVITY; INFLAMMATION; INNATE IMMUNITY; MAST CELL; NONHUMAN; PATHOPHYSIOLOGY; UMBILICAL CORD BLOOD; UPREGULATION; VIRUS INFECTION; BIOLOGICAL MODEL; CELL SEPARATION; CYTOLOGY; FETUS BLOOD; FLOW CYTOMETRY; IMMUNOLOGY; METABOLISM; VIROLOGY;

DENGUE VIRUS;

ANTIBODIES; ANTIVIRAL AGENTS; CELL LINE; CELL SEPARATION; CHEMOKINES; DENGUE; DENGUE VIRUS; FETAL BLOOD; FLOW CYTOMETRY; HUMANS; INTERFERONS; MAST CELLS; MODELS, BIOLOGICAL; POLY I-C; RNA; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 84859127328     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0034055     Document Type: Article

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