IL-10 Levels in Dengue Patients: Some Findings from the Exceptional Epidemiological Conditions in Cuba

Journal of Medical Virology

Volumn 73, Issue 2, 2004, Pages 230-234

  Pérez, Ana B ^a   García, Gissel ^a   Sierra, Beatriz ^a   Alvarez, Mayling ^a   Vázquez, Susana ^a   Cabrera, María V ^b   Rodríguez, Rosmary ^a   Rosario, Delfina ^a   Martínez, Eric ^c   Denny, Thomas ^d   Guzmán, María G ^a  

^a INSTITUTO DE MEDICINA TROPICAL PEDRO KOURÍ   (Cuba)

^b Medical University of Santiago de Cuba   (Cuba)

^c MINISTERIO DE SALUD PÚBLICA   (Cuba)

^d RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

Cytokines; Dengue; Dengue haemorrhagic fever; RANTES

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 12; RANTES;

ADOLESCENT; ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CUBA; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENGUE; DENGUE VIRUS; DISEASE ASSOCIATION; EPIDEMIOLOGICAL DATA; EVALUATION; HOSPITALIZATION; HUMAN; PATHOGENESIS; SUPERINFECTION; VIRUS PATHOGENESIS;

ADOLESCENT; ADULT; CUBA; DENGUE; DENGUE HEMORRHAGIC FEVER; HUMANS; INTERLEUKIN-10; INTERLEUKIN-12; MIDDLE AGED; RANTES;

EID: 11144354196     PISSN: 01466615     EISSN: None     Source Type: Journal    
DOI: 10.1002/jmv.20080     Document Type: Article

References (29)

1. Avirutnan P, Malasit P, Seliger B, Bhakdi S, Husmann M. 1998. Dengue virus infection of human endothelial cells leads to chemokine production, complement activation, and apoptosis. J Immunol 161:6338-6346.
2. Azeredo EL, Zagne SM, Santiago MA, Gouvea AS, Santana AA, Neves-Souza PC, Nogueira RM, Miagostovich MP, Kubelka CF. 2001. Characterisation of lymphocyte response and cytokine patterns in patients with Dengue Fever. Immunobiology 204:494-507.
3. Bussolati B, Rollino C, Mariano F, Quarello F, Camussi G. 2000. IL-10 stimulates production of platelet-activating factor by monocytes of patients with active systemic lupus erythematosus (SLE). Clin Exp Immunol 122:471-476.
4. Chaturvedi UC, Raghupathy R, Pacsa AS, Elbishbishi EA, Agarwal R, Nagar R, Nisra A, Kapoor S, Mathur A, Khan MAY, Azizieh F. 1999. Shift from a Th1-type response to Th2-type in dengue haemorhagic fever. Curr Sci 76:63-69.
5. Chaturvedi UC, Agarwal R, Elbishbishi EA, Mustafa AS. 2000. Cytokine cascade in dengue hemorrhagic fever: Implications for pathogenesis. FEMS Immunol Med Microbiol 28:183-188.
6. Chen RF, Yeh WT, Yang MY, Yang KD. 2001. A model of the real-time correlation of viral titers with immune reactions in antibody-dependent enhancement of dengue-2 infections. FEMS Immunol Med Microbiol 30:1-7.
7. Green S, Vaughn DW, Kalayanarooj S, Nimmammitya S, Suntayakorn S, Nisalak A, Rothman AL, Ennis FA. 1999a. Elevated plasma interleukin-10 levels in acute dengue correlate with disease severity. J Med Virol 59:329-334.
8. Green S, Pichyangkul S, Vaughn DW, Kalayanarooj S, Nimmannitya S, Nisalak A, Kurane I, Rothman AL, Ennis FA. 1999b. Early CD69 expression on peripheral blood lymphocytes from children with dengue hemorrhagic fever. J Infect Dis 180: 1429-1435.
9. Guzman MG, Alvarez M, Rodriguez R, Rosario D, Vazques S, Valdes L, Cabrera MV, Kouri G. 1999. Fatal dengue hemorrhagic fever in Cuba, 1997. Int J Inf Dis 3:130-135.
10. Guzman MG, Kouri G, Valdes L, Bravo J, Alvarez M, Vazques S, Delgado I, Halstead SB. 2000. Epidemiologic studies on Dengue in Santiago de Cuba, 1997. Am J Epidemiol 152:793-799.
11. Halstead SB. 1988. Pathogenesis of dengue. Challenge to molecular biology. Science 239:476-481.
12. Janabi N, Hau I, Tardieu M. 1999. Negative feedback between prostaglandin and α- and β-chemokine synthesis in human microglial cells and astrocytes. J Immunol 162:1701-1706.
13. Kouri GP, Guzman MG, Bravo JR. 1987. Why dengue haemorrhagic fever in Cuba? 2. An integral analysis. Trans R Soc Trop Med Hyg 81:821-823.
14. Kouri GP, Guzman MG, Valdes L, Carbonel I, del Rosario D, Vazquez S, Laferte J, Delgado J, Cabrera MV. 1998. Reemergence of dengue in Cuba: A 1997 epidemic in Santiago de Cuba. Emerg Infect Dis 4:89-92.
15. Kurane I, Ennis FA. 1992. Cytokines in dengue virus infections: Role of cytokines in the pathogenesis of dengue hemorrhagic fever. Semin Virol 4:121-127.
16. Kurane I, Takasaki T. 2001. Dengue Fever and dengue hemorrhagic fever: Challenges of controlling an enemy still at large. Rev Med Virol 11:301-311.
17. Libraty DH, Endy TP, Houng HSH, Green S, Kalayanarooj S, Suntayakorn S, Chansiriwongs W, Vaughn DW, Nisalak A, Ennis FA, Rothman AL. 2002. Differing influences of virus burden and immune activation on diesease severity in secondary dengue-3 virus infections. J Infect Dis 185:1213-1221.
18. Mahalingam S, Lidbury BA. 2002. Suppression of lipopolysaccharide-induced antiviral transcription factor (STAT-1 and NF-kappa B) complexes by antibody-dependent enhancement of macrophage infection by Ross River virus. Proc Natl Acad Sci USA 99:13819-13824.
19. Mongkolsapaya J, Dejnirattisai W, Xu XN, Vasanawathana S, Tangthawornchaikul N, Chairunsri A, Sawas S, Duangchinda T, Dong T, Rowland-Jones S, Yenchitsomanus P, Mc Michael A, Malasit P, Secreaton G. 2003. Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever. Nat Med 9:921-927.
20. Morens DM, Halstead SB, Larsen LK. 1985. Comparison of dengue virus plaque reduction neutralization by macro and "semi-micro" methods in LLCMK2 cells. Microbiol Immunol 29:1197-1205.
21. Pacsa AS, Agarwal R, Elbishbishi RA, Chaturvedi UC, Nagar R, Mustafa AC. 2000. Role of interleukin-12 in patients with dengue hemorrhagic fever. FEMS Immunol Med Microbiol 28:151-155.
22. Rodriguez-Roche R, Alvarez M, Guzman MG, Morier L, Kouri G. 2000. Comparison of rapid centrifugation assay with conventional tissue culture method for isolation of dengue 2 virus in C6/36-HT cells. J Clin Microbiol 38:3508-3510.
23. Rosario D, Alvarez M, Diaz J, Contreras R, Rodriguez R, Vazquez S, Guzman MG. 1998. Polymerase chain reaction for rapid detection and serotyping of dengue viruses in clinical samples. Pan Am J Public Health 4:1-5.
24. Rothman AL, Ennis FA. 1999. Immunopathogenesis of Dengue hemorrhagic fever. Virology 257:1-6.
25. Valdes L, Guzman MG, Kouri G, Delgado J, Carbonell I, Cabrera MV, Rosario D, Vazquez S. 1999. Epidemiology of dengue and hemorrhagic dengue in Santiago, Cuba 1997. Rev Panam Salud Publica 6:16-25.
26. Vazquez S, Bravo JR, Perez AB, Guzman MG. 1997. Inhibition ELISA. Its utility for classifying a case of dengue. Rev Cubana Med Trop 49:108-112.
27. Vazquez S, Saenz E, Huelva G, Gonzalez A, Kouri G, Guzman M. 1998. Detection of IgM against the dengue++ virus in whole blood absorbed on filter paper. Rev Panam Salud Publica 3:174-178.
28. WHO. 1997. Dengue hemorrhagic fever: Diagnosis, treatment and control. 2nd edn. Geneva: World Health Organization; 1997. pp 12-23.
29. Yang KD, Yeh WT, Yang MY, Chen RF, Shaio MF. 2001. Antibody-dependent enhancement of heterotypic dengue infections involved in suppression of IFNgamma production. J Med Virol 63:150-157.