The role of the vitamin D receptor and ERp57 in photoprotection by 1α,25-dihydroxyvitamin D 3

Molecular Endocrinology

Volumn 26, Issue 4, 2012, Pages 574-582

  Sequeira, Vanessa B ^a   Rybchyn, Mark S ^a   Tongkao on, Wannit ^a   Gordon Thomson, Clare ^a   Malloy, Peter J ^b   Nemere, Ilka ^c   Norman, Anthony W ^d   Reeve, Vivienne E ^a   Halliday, Gary M ^e   Feldman, David ^b   Mason, Rebecca S ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UTAH STATE UNIVERSITY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e ROYAL PRINCE ALFRED HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITRIOL; CELL PROTEIN; ENDOPLASMIC RETICULUM STRESS PROTEIN 57; NEUTRALIZING ANTIBODY; NEUTRALIZING ANTIBODY AB099; PROTEIN P53; THYMINE; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR;

ARTICLE; CONTROLLED STUDY; DNA DAMAGE; ENDOPLASMIC RETICULUM STRESS; FIBROBLAST; GENE MUTATION; GENOMICS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIGAND BINDING; MOLECULAR MECHANICS; NEWBORN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RICKETS; SKIN PROTECTION; ULTRAVIOLET RADIATION; UPREGULATION;

CALCITRIOL; CELL NUCLEUS; CELLS, CULTURED; FIBROBLASTS; HUMANS; HYPOPHOSPHATEMIC RICKETS, X-LINKED DOMINANT; MUTATION, MISSENSE; PROTEIN BINDING; PROTEIN DISULFIDE-ISOMERASES; PROTEIN STRUCTURE, TERTIARY; PYRIMIDINE DIMERS; RECEPTORS, CALCITRIOL; TRANSCRIPTIONAL ACTIVATION; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS; UP-REGULATION;

EID: 84859117990     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2011-1161     Document Type: Article

References (32)

1. Ravanat JL, Douki T, Cadet J 2001 Direct and indirect effects ofUV radiation on DNA and its components. J Photochem Photobiol B 63:88-102
2. Rochette PJ, Therrien JP, Drouin R, Perdiz D, Bastien N, Drobetsky EA, Sage E 2003 UVA-induced cyclobutane pyrimidine dimers form predominantly at thymine-thymine dipyrimidines and correlate with the mutation spectrum in rodent cells. Nucl Acids Res 31: 2786-2794
3. 3 in an in vitro human skin equivalent model. J Invest Dermatol 117:1179-1185
4. 3 and analogues protect primary human keratinocytes against UVB-induced DNA damage. Photochem Photobiol Sci B 78:141-148
5. 3 and its analogs. J Steroid Biochem Mol Biol 97:137-143
6. Wong G, Gupta R, Dixon KM, Deo SS, Choong SM, Halliday GM, Bishop JE, Ishizuka S, Norman AW, Posner GH, Mason RS 2004 1,25-Dihydroxyvitamin D and three low-calcemic analogs decrease UV-inducedDNAdamage via the rapid response pathway. J Steroid Biochem Mol Biol 89-90:567-570
7. Gupta R, Dixon KM, Deo SS, Holliday CJ, Slater M, Halliday GM, Reeve VE, Mason RS 2007 Photoprotection by 1,25dihydroxyvitamin D is associated with an increase in p53 and a decrease in nitric oxide products. J Invest Dermatol 127:707-715
8. Norman AW, Mizwicki MT, Norman DPG 2004 Steroid-hormone rapid actions, membrane receptors and a conformational ensemble model. Nat Rev Drug Discov 3:27-41
9. 3 in vivo and in vitro. Mol Endocrinol 18:2660-2671
10. 3 is present in an intestinal caveolae membrane fraction. Biochem Biophys Res Commun 298:414-419
11. 3 requires the presence of a functional vitamin D nuclear receptor. Proc Natl Acad Sci USA 101:1589-1594
12. 3 induces translocation of the vitamin D receptor (VDR) to the plasma membrane in skeletal muscle cells. J Cell Biochem 86:128-135
13. Menegaz D, Mizwicki MT, Barrientos-Duran A, Chen N, Henry HL, Norman AW 2011 Vitamin D receptor (VDR) regulation of voltage-gated chloride channels by ligands preferring a VDR-alternative pocket (VDR-AP). Mol Endocrinol 25:1289-1300
14. 3 signaling. Proc Natl Acad Sci USA 101:12876-12881
15. Mizwicki MT, Menegaz D, Yaghmaei S, Henry HL, Norman AW 2010 A molecular description of ligand binding to the two overlapping binding pockets of the nuclear vitamin D receptor (VDR): structure-function implications. J Steroid Biochem Mol Biol 121: 98-105
16. 3-MARRS (membrane-associated, rapid response steroid-binding) receptor/ PDIA3/Erp57. J Biol Chem 285:31859-31866
17. 3. I. Chick intestine. Am J Physiol Endocrinol Metabol 278:E1104-E1114
18. 3-MARRS) and phosphate uptake in intestinal cells. Proc Natl Acad Sci USA 101:7392-7397
19. 3-MARRS) binding protein. J Steroid Biochem Mol Biol 89-90:281-285
20. 3 requires caveolae and caveolin-1. J Bone Miner Res 21:1637-1647
21. Malloy PJ, Pike JW, Feldman D 1999 The vitamin D receptor and the syndrome of hereditary 1,25-dihydroxyvitamin D-resistant rickets. Endocr Rev 20:156-188
22. Forghani N, Lum C, Krishnan S, Wang J, Wilson DM, Blackett PR, Malloy PJ, Feldman D 2010 Two new unrelated cases of hereditary 1,25-dihydroxyvitamin D-resistant rickets with alopecia resulting from the same novel nonsense mutation in the vitamin D receptor gene. J Pediatr Endocrinol Metab 23:843-850
23. Malloy PJ, Wang J, Srivastava T, Feldman D 2010 Hereditary 1,25-dihydroxyvitamin D-resistant rickets with alopecia resulting from a novel missense mutation in the DNA-binding domain of the vitamin D receptor. Mol Genet Metab 99:72-79
24. Malloy PJ, Xu R, Cattani A, Reyes L, Feldman D 2004 A unique insertion/substitution in helix H1 of the vitamin D receptor ligand binding domain in a patient with hereditary 1,25-dihydroxyvitamin D-resistant rickets. J Bone Miner Res 19:1018-1024
25. 3 and their physiological significance in osteoblasts. Steroids 69:561-565
26. 3 require the vitamin D receptor and influence 24-hydroxylase activity: studies in human skin fibroblasts bearing vitamin D receptor mutations. J Biol Chem 279:7591-7597
27. Wu W, Beilhartz G, Roy Y, Richard CL, Curtin M, Brown L, Cadieux D, Coppolino M, Farach-Carson MC, Nemere I, Meckling KA 2010 Nuclear translocation of the 1,25D3-MARRS (membrane associated rapid response to steroids) receptor protein and NFκB in differentiating NB4 leukemia cells. Exp Cell Res 316:1101-1108
28. Santos SG, Campbell EC, Lynch S, Wong V, Antoniou AN, Powis SJ 2007 Major histocompatibility complex class I-ERp57-tapasin interactions within the peptide-loading complex. J Biol Chem 282: 17587-17593
29. Pollock S, Kozlov G, Pelletier MF, Trempe JF, Jansen G, Sitnikov D, Bergeron JJ, Gehring K, Ekiel I, Thomas DY 2004 Specific interaction of ERp57 and calnexin determined by NMR spectroscopy and an ER two-hybrid system. EMBO J 23:1020-1029
30. Hall PA, McKee PH, Menage HD, Dover R, Lane DP 1993 High levels of p53 protein in UV-irradiated normal human skin. Oncogene 8:203-207
31. Kochevar IE, Pathak MA, Parrish JA 1999 Photophysics, photochemistry, and photobiology. In: Freedberg IM, Eisen AZ, Wolff K, Austen KF, Goldsmith LA, Katz SI, Fitzpatrick TB, eds. Fitzpatrick's dermatology in general medicine. Vol. 1. 5th ed. New York: McGraw Hill, Health Provisions Division
32. Smith ML, Seo YR 2002 p53 regulation of DNA excision repair pathways. Mutagenesis 17:149-156