1,25-Dihydroxyvitamin D3 and analogues protect primary human keratinocytes against UVB-induced DNA damage

Journal of Photochemistry and Photobiology B: Biology

Volumn 78, Issue 2, 2005, Pages 141-148

  De Haes, Petra ^a,b   Garmyn, Marjan ^a,b   Verstuyf, Annemieke ^a   De Clercq, Pierre ^c   Vandewalle, Maurits ^c   Degreef, Hugo ^b   Vantieghem, Katleen ^a   Bouillon, Roger ^a   Segaert, Siegfried ^a,b  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^c GHENT UNIVERSITY   (Belgium)

Author keywords

1,25 Dihydroxyvitamin D3; Cyclobutane pyrimidine dimers; DNA damage; Keratinocytes; Ultraviolet B; Vitamin D analogues

Indexed keywords

19 NOR 14 EPI 23 YNE CALCITRIOL; 19 NOR 14,20 BIS EPI 23 YNE CALCITRIOL; ANTINEOPLASTIC AGENT; CALCITRIOL; CALCITRIOL DERIVATIVE; DNA; TX 522; TX 527; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER PREVENTION; CARCINOGENESIS; CELL PROTECTION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DOSE RESPONSE; DRUG MECHANISM; DRUG POTENCY; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; INCUBATION TIME; KERATINOCYTE; PRIORITY JOURNAL; RADIATION EXPOSURE; RISK FACTOR; SKIN CANCER; ULTRAVIOLET B RADIATION;

CELL PROLIFERATION; CELLS, CULTURED; DNA DAMAGE; HUMANS; KERATINOCYTES; PYRIMIDINE DIMERS; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS; VITAMIN D;

EID: 12344258593     PISSN: 10111344     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jphotobiol.2004.09.010     Document Type: Article

References (29)

1. F.R. de Gruijl H.J. van Kranen L.H. Mullenders UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer J. Photochem. Photobiol. B: Biol. 63 2001 19-27
2. J.L. Ravanat T. Douki J. Cadet Direct and indirect effects of UV radiation on DNA and its components J. Photochem. Photobiol. B: Biol. 63 2001 88-102
3. M.F. Holick Evolution and function of vitamin D Recent Res. Cancer Res. 164 2003 3-28
4. R. Bouillon Vitamin D: From photosynthesis, metabolism, and action to clinical applications in L.J. De Groot J.L. Jameson (Eds.) Endocrinology 2000 WB Saunders Philadelphia 1009-1028
5. 3 in cultured human epidermal keratinocytes J. Invest. Dermatol. 109 1997 46-54
6. D.D. Bikle Vitamin D regulated keratinocyte differentiation J. Cell. Biochem. 92 2004 436-444
7. P.C. van de Kerkhof W.H. Vissers The topical treatment of psoriasis Skin Pharmacol. Appl. Skin Physiol. 16 2003 69-83
8. S.J. Courtois S. Segaert H. Degreef R. Bouillon M. Garmyn Ultraviolet B suppresses vitamin D receptor gene expression in keratinocytes Biochem. Biophys. Res. Commun. 246 1998 64-69
9. 3 inhibits ultraviolet B-induced apoptosis, Jun kinase activation, and interleukin-6 production in primary human keratinocytes J. Cell. Biochem. 89 2003 663-673
10. 3 protect human keratinocytes against the effects of UVB Arch. Dermatol. Res. 295 2004 527-534
11. L. Roza K.J. van der Wulp S.J. MacFarlane P.H. Lohman R.A. Baan Detection of cyclobutane thymine dimers in DNA of human cells with monoclonal antibodies raised against a thymine dimer-containing tetranucleotide Photochem. Photobiol. 48 1988 627-633
12. D. Decraene P. Agostinis A. Pupe P. De Haes M. Garmyn Acute response of human skin to solar radiation: Regulation and function of the p53 protein J. Photochem. Photobiol. B: Biol. 63 2001 78-83
13. W. Krek J.A. DeCaprio Cell synchronization Meth. Enzymol. 254 1995 114-124
14. 3 responsive elements J. Bone Miner. Res. 16 2001 625-638
15. H. Hönigsmann Erythema and pigmentation Photodermatol. Photoimmunol. Photomed. 18 2002 75-81
16. G.J. Fisher S. Kang J. Varani Z. Bata-Csorgo Y. Wan S. Datta J.J. Voorhees Mechanisms of photoaging and chronological skin aging Arch. Dermatol. 138 2002 1462-1470
17. 3 on ultraviolet light B-induced damage in keratinocyte and its mechanism of action J. Dermatol. Sci. 18 1998 11-18
18. 3-induced metallothionein in photoprotection against UVB injury in mouse skin and cultured rat keratinocytes J. Dermatol. Sci. 9 1995 203-208
19. C.S. Sander H. Chang F. Hamm P. Elsner J.J. Thiele Role of oxidative stress and the antioxidant network in cutaneous carcinogenesis Int. J. Dermatol. 43 2004 326-335
20. 3 in cultured cells and in mice Proc. Natl. Acad. Sci. USA 84 1987 8810-8813
21. K. Hanada D. Sawamura K. Tamai T. Baba I. Hashimoto T. Muramatsu N. Miura A. Naganuma Novel function of metallothionein in photoprotection: metallothionein-null mouse exhibits reduced tolerance against ultraviolet B injury in the skin J. Invest. Dermatol. 111 1998 582-585
22. A.A. Vink B. Henegouwen O. Nikaido R.A. Baan L. Roza Removal of UV-induced DNA lesions in mouse epidermis soon after irradiation J. Photochem. Photobiol. B: Biol. 24 1994 25-31
23. C.L. Peterson C. Logie Recruitment of chromatin remodelling machines J. Cell. Biochem. 78 2000 179-185
24. G. Wong R. Gupta K.M. Dixon S.S. Deo S.M. Choong G.M. Halliday J.E. Bishop S. Ishizuka A.W. Norman G.H. Posner R.S. Mason 1,25-DihydroxyvitamiD D and three low-calcemic analogs decrease UV-induced DNA damage via the rapid response pathway J. Steroid Biochem. Mol. Biol. 89-90 2004 567-570
25. M. Al Mahroos M. Yaar T.J. Phillips J. Bhawan B.A. Gilchrest Effect of sunscreen application on UV-induced thymine dimers Arch. Dermatol. 138 2002 1480-1485
26. S.K. Katiyar Skin photoprotection by green tea: Antioxidant and immunomodulatory effects Curr. Drug Target Immune Endocr. Metabol. Disord. 3 2003 234-242
27. C. Antille C. Tran O. Sorg P. Carraux L. Didierjean J.H. Saurat Vitamin A exerts a photoprotective action in skin by absorbing ultraviolet B radiation J. Invest. Dermatol. 121 2003 1163-1167
28. H. Wei R. Saladi Y. Lu Y. Wang S.R. Palep J. Moore R. Phelps E. Shyong M.G. Lebwohl Isoflavone genistein: Photoprotection and clinical implications in dermatology J. Nutr. 133 2003 3811S-3819S
29. S. Dhanalakshmi G.U. Mallikarjuna R.P. Singh R. Agarwal Silibinin prevents ultraviolet radiation-caused skin damages in SKH-1 hairless mice via a decrease in thymine dimer positive cells and an up-regulation of p53-p21/Cip1 in epidermis Carcinogenesis 25 2004 1459-1465