Dynamic deformation characteristics of porcine aortic valve leaflet under normal and hypertensive conditions

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 298, Issue 2, 2010, Pages

  Yap, Choon Hwai ^a   Kim, Hee Sun ^b   Balachandran, Kartik ^a   Weiler, Michael ^a   Haj Ali, Rami ^b,c   Yoganathan, Ajit P ^a  

^a EMORY UNIVERSITY   (United States)

^b Georgia Institute of Technology   (United States)

^c TEL AVIV UNIVERSITY   (Israel)

Author keywords

Dual camera photogrammetry; Dynamic strain; Dynamic stretch; Hypertension

Indexed keywords

ANIMAL TISSUE; AORTA ROOT; AORTA VALVE; ARTICLE; DIASTOLE; DISEASE SEVERITY; DYNAMICS; FORCE; HYPERTENSION; IN VITRO STUDY; NONHUMAN; PRESSURE; PRIORITY JOURNAL; SWINE; SYSTOLE; WAVEFORM;

ANIMALS; AORTA; AORTIC VALVE; BIOMECHANICS; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; FEMALE; HEART VENTRICLES; HYPERTENSION; MODELS, BIOLOGICAL; REGIONAL BLOOD FLOW; SWINE;

EID: 74949102206     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00040.2009     Document Type: Article

References (34)

1. Adamczyk MM, Vesely I. Characteristics of compressive strains in porcine aortic valves cusps. J Heart Valve Dis 11: 75-83, 2002.
2. Baicu CF, Zile MR, Aurigemma GP, Gaasch WH. Left ventricular systolic performance, function, and contractility in patients with diastolic heart failure. Circulation 111: 2306-2312, 2005.
3. Balachandran K, Konduri S, Sucosky P, Jo H, Yoganathan AP. An ex vivo study of the biological properties of porcine aortic valves in response to circumferential cyclic stretch. Ann Biomed Eng 34: 1655-1665, 2006.
4. Balachandran K, Sucosky P, Jo H, Yoganathan AP. Elevated cyclic stretch alters matrix remodeling in aortic valve cusps: implications for degenerative aortic valve disease. Am J Physiol Heart Circ Physiol 296: H756-H764, 2009.
5. Billiar KL, Sacks MS. Biaxial mechanical properties of the natural and glutaraldehyde treated aortic valve cusp. I. Experimental results. J Biomech Eng 122: 23-30, 2000.
6. Butcher JT, Tressel S, Johnson T, Turner D, Sorescu G, Jo H, Nerem RM. Transcriptional profiles of valvular and vascular endothelial cells reveal phenotypic differences: influence of shear stress. Arterioscler Thromb Vasc Biol 26: 69-77, 2006.
7. Cataloglu A, Clark RE, Gould PL. Stress analysis of aortic valve leaflets with smoothed geometrical data. J Biomech 10: 153-158, 1977.
8. Cataloglu A, Gould PL, Clark RE. Validation of a simplified mathematical model for the stress analysis of human aortic heart valves. J Biomech 8: 347-348, 1975.
9. Chatzizisis YS, Coskun AU, Jonas M, Edelman ER, Feldman CL, Stone PH. Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: molecular, cellular, and vascular behavior. J Am Coll Cardiol 49: 2379-2393, 2007.
10. Davies PF, Spaan JA, Krams R. Shear stress biology of the endothelium. Ann Biomed Eng 33: 1714-1718, 2005.
11. Freeman RV, Otto CM. Spectrum of calcific aortic valve disease: pathogenesis, disease progression, and treatment strategies. Circulation 111: 3316-3326, 2005.
12. Gao BZ, Pandya S, Arana C, Hwang NH. Bioprosthetic heart valve leaflet deformation monitored by double-pulse stereo photogrammetry. Ann Biomed Eng 30: 11-18, 2002.
13. Goldbarg SH, Elmariah S, Miller MA, Fuster V. Insights into degenerative aortic valve disease. J Am Coll Cardiol 50: 1205-1213, 2007.
14. He Z, Ritchie J, Grashow JS, Sacks MS, Yoganathan AP. In vitro dynamic strain behavior of the mitral valve posterior leaflet. J Biomech Eng 127: 504-511, 2005.
15. Jensen MO, Lemmon JD, Gessaghi VC, Conrad CP, Levine RA, Yoganathan AP. Harvested porcine mitral xenograft fixation: impact on fluid dynamic performance. J Heart Valve Dis 10: 111-124, 2001.
16. Lindroos M, Kupari M, Heikkila J, Tilvis R. Prevalence of aortic valve abnormalities in the elderly: an echocardiographic study of a random population sample. J Am Coll Cardiol 21: 1220-1225, 1993.
17. Mohler ER 3rd. Mechanisms of aortic valve calcification. Am J Cardiol 94: 1396-1402, 2004.
18. Otto CM, Kuusisto J, Reichenbach DD, Gown AM, O'Brien KD. Characterization of the early lesion of "degenerative" valvular aortic stenosis. Histological and immunohistochemical studies. Circulation 90: 844-853, 1994.
19. Pai RG. Degenerative valve disease. J Am Coll Cardiol 48: 2601; author reply 2602, 2006.
20. Rabkin SW. The association of hypertension and aortic valve sclerosis. Blood Press 14: 264-272, 2005.
21. Rajamannan NM, Gersh B, Bonow RO. Calcific aortic stenosis: from bench to the bedside- emerging clinical and cellular concepts. Heart 89: 801-805, 2003.
22. Sacks MS, He Z, Baijens L, Wanant S, Shah P, Sugimoto H, Yoganathan AP. Surface strains in the anterior leaflet of the functioning mitral valve. Ann Biomed Eng 30: 1281-1290, 2002.
23. Sacks MS, Smith DB, Hiester ED. The aortic valve microstructure: effects of transvalvular pressure. J Biomed Mater Res 41: 131-141, 1998.
24. Smith DB, Sacks MS, Vorp DA, Thornton M. Surface geometric analysis of anatomic structures using biquintic finite element interpolation. Ann Biomed Eng 28: 598-611, 2000.
25. Stella JA, Liao J, Sacks MS. Time-dependent biaxial mechanical behavior of the aortic heart valve leaflet. J Biomech 40: 3169-3177, 2007.
26. Stella JA, Sacks MS. On the biaxial mechanical properties of the layers of the aortic valve leaflet. J Biomech Eng 129: 757-766, 2007.
27. Stephan PJ, Henry AC 3rd, Hebeler RF Jr, Whiddon L, Roberts WC. Comparison of age, gender, number of aortic valve cusps, concomitant coronary artery bypass grafting, and magnitude of left ventricular-systemic arterial peak systolic gradient in adults having aortic valve replacement for isolated aortic valve stenosis. Am J Cardiol 79: 166-172, 1997.
28. Sun W, Abad A, Sacks MS. Simulated bioprosthetic heart valve deformation under quasi-static loading. J Biomech Eng 127: 905-914, 2005.
29. Thubrikar M, Piepgrass WC, Deck JD, Nolan SP. Stresses of natural versus prosthetic aortic valve leaflets in vivo. Ann Thorac Surg 30: 230-239, 1980.
30. Vesely I, Noseworthy R. Micromechanics of the fibrosa and the ventricularis in aortic valve leaflets. J Biomech 25: 101-113, 1992.
31. Warnock JN, Burgess SC, Shack A, Yoganathan AP. Differential immediate-early gene responses to elevated pressure in porcine aortic valve interstitial cells. J Heart Valve Dis 15: 34-41; discussion 42, 2006.
32. Weston MW, Yoganathan AP. Biosynthetic activity in heart valve leaflets in response to in vitro flow environments. Ann Biomed Eng 29: 752-763, 2001.
33. Xing Y, Warnock JN, He Z, Hilbert SL, Yoganathan AP. Cyclic pressure affects the biological properties of porcine aortic valve leaflets in a magnitude and frequency dependent manner. Ann Biomed Eng 32: 1461-1470, 2004.
34. Yacoub MH, Takkenberg JJ. Will heart valve tissue engineering change the world? Nat Clin Pract Cardiovasc Med 2: 60-61, 2005.