Does brain slices from pentylenetetrazole-kindled mice provide a more predictive screening model for antiepileptic drugs?

European Journal of Pharmacology

Volumn 682, Issue 1-3, 2012, Pages 43-49

  Hansen, Suzanne L ^a   Sterjev, Zoran ^a,b   Werngreen, Marie ^a   Simonsen, Bodil J ^a   Knudsen, Katrine E ^a   Nielsen, Ane H ^a   Pedersen, Mikael E ^a   Badolo, Lassiana ^a   Kristiansen, Uffe ^a   Vestergaard, Henrik T ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b SS Cyril and Methodius University Faculty of Pharmacy   (Macedonia)

Author keywords

Anticonvulsant; Cortical wedge preparation; Observational parameter; PTZ kindling

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; CITALOPRAM; FOSPHENYTOIN SODIUM; PENTETRAZOLE; PHENOBARBITAL; PHENYTOIN; SODIUM CHLORIDE; TIAGABINE; VALPROIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; BRAIN CORTEX; BRAIN SLICE; CLONIC SEIZURE; CONTROLLED STUDY; CONVULSION; DISEASE DURATION; DISEASE SEVERITY; DRUG SCREENING; IN VITRO STUDY; IN VIVO STUDY; INCIDENCE; KINDLING; LATENT PERIOD; MALE; MOUSE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; SEIZURE; STATISTICAL MODEL;

ANIMALS; ANTICONVULSANTS; BRAIN; CEREBRAL CORTEX; DRUG EVALUATION, PRECLINICAL; MALE; MICE; PENTYLENETETRAZOLE;

EID: 84859106303     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.01.044     Document Type: Article

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