-
1
-
-
0023038949
-
Effects of the benzodiazepine antagonists RO 15-1788, CGS-8216 and PK-11195 on amygdaloid kindled seizures and the anticonvulsant efficacy of diazepam
-
Albertson T.E., Walby W.F. Effects of the benzodiazepine antagonists RO 15-1788, CGS-8216 and PK-11195 on amygdaloid kindled seizures and the anticonvulsant efficacy of diazepam. Neuropharmacology. 25:1986;1205-1211.
-
(1986)
Neuropharmacology
, vol.25
, pp. 1205-1211
-
-
Albertson, T.E.1
Walby, W.F.2
-
2
-
-
0035847286
-
Long-term reduction of benzodiazepine receptor density in the rat cerebellum by acute seizures and kindling and its recovery 6 months later by a pentylenetetrazole challenge
-
Bazyan A.S., Zhulin V.V., Karpova M.N., Klishina N.Y., Glebov R.N. Long-term reduction of benzodiazepine receptor density in the rat cerebellum by acute seizures and kindling and its recovery 6 months later by a pentylenetetrazole challenge. Brain Res. 888:2001;212-220.
-
(2001)
Brain Res.
, vol.888
, pp. 212-220
-
-
Bazyan, A.S.1
Zhulin, V.V.2
Karpova, M.N.3
Klishina, N.Y.4
Glebov, R.N.5
-
3
-
-
0031888527
-
Reversal of behavioral effects of pentylenetetrazol by the neuroactive steroid ganaxolone
-
Beekman M., Ungard J.T., Gasior M., Carter R.B., Dijkstra D., Goldberg S.R., Witkin J.M. Reversal of behavioral effects of pentylenetetrazol by the neuroactive steroid ganaxolone. J. Pharmacol. Exp. Ther. 284:1998;868-877.
-
(1998)
J. Pharmacol. Exp. Ther.
, vol.284
, pp. 868-877
-
-
Beekman, M.1
Ungard, J.T.2
Gasior, M.3
Carter, R.B.4
Dijkstra, D.5
Goldberg, S.R.6
Witkin, J.M.7
-
4
-
-
0020434375
-
Antinociceptive and anticonvulsive effect of THIP, a pure GABA agonist
-
Christensen A.V., Larsen J.J. Antinociceptive and anticonvulsive effect of THIP, a pure GABA agonist. Pol. J. Pharmacol. Pharm. 34:1982;127-134.
-
(1982)
Pol. J. Pharmacol. Pharm.
, vol.34
, pp. 127-134
-
-
Christensen, A.V.1
Larsen, J.J.2
-
5
-
-
0026701569
-
Decrease in GABAergic function induced by pentylenetetrazol kindling in rats: Antagonism by MK-801
-
Corda M.G., Orlandi M., Giorgi O. Decrease in GABAergic function induced by pentylenetetrazol kindling in rats: antagonism by MK-801. J. Pharmacol. Exp. Ther. 262:1992;792-800.
-
(1992)
J. Pharmacol. Exp. Ther.
, vol.262
, pp. 792-800
-
-
Corda, M.G.1
Orlandi, M.2
Giorgi, O.3
-
6
-
-
0034528441
-
The effects of neurosteroids on picrotoxin-, bicuculline- and NMDA-induced seizures, and a hypnotic effect of ethanol
-
Czlonkowska A.I., Krzascik P., Sienkiewicz-Jarosz H., Siemiatkowski M., Szyndler J., Bidzinski A., Plaznik A. The effects of neurosteroids on picrotoxin-, bicuculline- and NMDA-induced seizures, and a hypnotic effect of ethanol. Pharmacol. Biochem. Behav. 67:2000;345-353.
-
(2000)
Pharmacol. Biochem. Behav.
, vol.67
, pp. 345-353
-
-
Czlonkowska, A.I.1
Krzascik, P.2
Sienkiewicz-Jarosz, H.3
Siemiatkowski, M.4
Szyndler, J.5
Bidzinski, A.6
Plaznik, A.7
-
7
-
-
0030929440
-
Phenytoin's effect on the spread of seizure activity in the amygdala kindling model
-
Ebert U., Cramer S., Loscher W. Phenytoin's effect on the spread of seizure activity in the amygdala kindling model. Naunyn-Schmiedeberg's Arch. Pharmacol. 356:1997;341-347.
-
(1997)
Naunyn-Schmiedeberg's Arch. Pharmacol.
, vol.356
, pp. 341-347
-
-
Ebert, U.1
Cramer, S.2
Loscher, W.3
-
8
-
-
0028171397
-
Molecular pharmacology of gamma-aminobutyric acid type a receptor agonists and partial agonists in oocytes injected with different alpha, beta, and gamma receptor subunit combinations
-
Ebert B., Wafford K.A., Whiting P.J., Krogsgaard-Larsen P., Kemp J.A. Molecular pharmacology of gamma-aminobutyric acid type A receptor agonists and partial agonists in oocytes injected with different alpha, beta, and gamma receptor subunit combinations. Mol. Pharmacol. 46:1994;957-963.
-
(1994)
Mol. Pharmacol.
, vol.46
, pp. 957-963
-
-
Ebert, B.1
Wafford, K.A.2
Whiting, P.J.3
Krogsgaard-Larsen, P.4
Kemp, J.A.5
-
9
-
-
0035501013
-
Changes in AMPA receptor binding and subunit messenger RNA expression in hippocampus and cortex in the pentylenetetrazole-induced "kindling" model of epilepsy
-
Ekonomou A., Smith A.L., Angelatou F. Changes in AMPA receptor binding and subunit messenger RNA expression in hippocampus and cortex in the pentylenetetrazole-induced "kindling" model of epilepsy. Brain Res. Mol. Brain Res. 95:2001;27-35.
-
(2001)
Brain Res. Mol. Brain Res.
, vol.95
, pp. 27-35
-
-
Ekonomou, A.1
Smith, A.L.2
Angelatou, F.3
-
10
-
-
0035151148
-
Altered activities of rat brain metabolic enzymes caused by pentylenetetrazol kindling and pentylenetetrazol-induced seizures
-
Erakovic V., Zupan G., Varljen J., Laginja J., Simonic A. Altered activities of rat brain metabolic enzymes caused by pentylenetetrazol kindling and pentylenetetrazol-induced seizures. Epilepsy Res. 43:2001;165-173.
-
(2001)
Epilepsy Res.
, vol.43
, pp. 165-173
-
-
Erakovic, V.1
Zupan, G.2
Varljen, J.3
Laginja, J.4
Simonic, A.5
-
11
-
-
0026659149
-
Relationship between benzodiazepine receptor occupancy and functional effects in vivo of four ligands of differing intrinsic efficacies
-
Facklam M., Schoch P., Bonetti E.P., Jenck F., Martin J.R., Moreau J.L., Haefely W.E. Relationship between benzodiazepine receptor occupancy and functional effects in vivo of four ligands of differing intrinsic efficacies. J. Pharmacol. Exp. Ther. 261:1992;1113-1121.
-
(1992)
J. Pharmacol. Exp. Ther.
, vol.261
, pp. 1113-1121
-
-
Facklam, M.1
Schoch, P.2
Bonetti, E.P.3
Jenck, F.4
Martin, J.R.5
Moreau, J.L.6
Haefely, W.E.7
-
12
-
-
0024449997
-
Animal models of the epilepsies
-
Fisher R.S. Animal models of the epilepsies. Brain Res. Brain Res. Rev. 14:1989;245-278.
-
(1989)
Brain Res. Brain Res. Rev.
, vol.14
, pp. 245-278
-
-
Fisher, R.S.1
-
13
-
-
0033000685
-
Changes in the gene expression of GABAA receptor subunit mRNAs in the septum of rats subjected to pentylenetetrazol-induced kindling
-
Follesa P., Tarantino A., Floris S., Mallei A., Porta S., Tuligi G., Cagetti E., Caddeo M., Mura A., Serra M., Biggio G. Changes in the gene expression of GABAA receptor subunit mRNAs in the septum of rats subjected to pentylenetetrazol-induced kindling. Brain Res. Mol. Brain Res. 70:1999;1-8.
-
(1999)
Brain Res. Mol. Brain Res.
, vol.70
, pp. 1-8
-
-
Follesa, P.1
Tarantino, A.2
Floris, S.3
Mallei, A.4
Porta, S.5
Tuligi, G.6
Cagetti, E.7
Caddeo, M.8
Mura, A.9
Serra, M.10
Biggio, G.11
-
15
-
-
0034101871
-
Acute and chronic effects of the synthetic neuroactive steroid, ganaxolone, against the convulsive and lethal effects of pentylenetetrazol in seizure-kindled mice: Comparison with diazepam and valproate
-
Gasior M., Ungard J.T., Beekman M., Carter R.B., Witkin J.M. Acute and chronic effects of the synthetic neuroactive steroid, ganaxolone, against the convulsive and lethal effects of pentylenetetrazol in seizure-kindled mice: comparison with diazepam and valproate. Neuropharmacology. 39:2000;1184-1196.
-
(2000)
Neuropharmacology
, vol.39
, pp. 1184-1196
-
-
Gasior, M.1
Ungard, J.T.2
Beekman, M.3
Carter, R.B.4
Witkin, J.M.5
-
16
-
-
0032476206
-
B receptor antagonism on the development of pentylenetetrazol-induced kindling in mice
-
B receptor antagonism on the development of pentylenetetrazol-induced kindling in mice. Brain Res. 809:1998;182-188.
-
(1998)
Brain Res.
, vol.809
, pp. 182-188
-
-
Getova, D.1
Froestl, W.2
Bowery, N.G.3
-
17
-
-
0014597998
-
A permanent change in brain function resulting from daily electrical stimulation
-
Goddard G.V., McIntyre D.C., Leech C.K. A permanent change in brain function resulting from daily electrical stimulation. Exp. Neurol. 25:1969;295-330.
-
(1969)
Exp. Neurol.
, vol.25
, pp. 295-330
-
-
Goddard, G.V.1
McIntyre, D.C.2
Leech, C.K.3
-
18
-
-
0026471112
-
Ucb L059, a novel anti-convulsant drug: Pharmacological profile in animals
-
Gower A.J., Noyer M., Verloes R., Gobert J., Wulfert E. ucb L059, a novel anti-convulsant drug: pharmacological profile in animals. Eur. J. Pharmacol. 222:1992;193-203.
-
(1992)
Eur. J. Pharmacol.
, vol.222
, pp. 193-203
-
-
Gower, A.J.1
Noyer, M.2
Verloes, R.3
Gobert, J.4
Wulfert, E.5
-
19
-
-
0027092554
-
Relative anticonvulsant effects of GABA mimetic and GABA modulatory agents
-
Holland K.D., McKeon A.C., Canney D.J., Covey D.F., Ferrendelli J.A. Relative anticonvulsant effects of GABA mimetic and GABA modulatory agents. Epilepsia. 33:1992;981-986.
-
(1992)
Epilepsia
, vol.33
, pp. 981-986
-
-
Holland, K.D.1
McKeon, A.C.2
Canney, D.J.3
Covey, D.F.4
Ferrendelli, J.A.5
-
20
-
-
0034892146
-
Pentylenetetrazole-induced inhibition of recombinant gamma-aminobutyric acid type a (GABA(A)) receptors: Mechanism and site of action
-
Huang R.Q., Bell-Horner C.L., Dibas M.I., Covey D.F., Drewe J.A., Dillon G.H. Pentylenetetrazole-induced inhibition of recombinant gamma-aminobutyric acid type A (GABA(A)) receptors: mechanism and site of action. J. Pharmacol. Exp. Ther. 298:2001;986-995.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.298
, pp. 986-995
-
-
Huang, R.Q.1
Bell-Horner, C.L.2
Dibas, M.I.3
Covey, D.F.4
Drewe, J.A.5
Dillon, G.H.6
-
21
-
-
0032563178
-
Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy
-
Klitgaard H., Matagne A., Gobert J., Wulfert E. Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy. Eur. J. Pharmacol. 353:1998;191-206.
-
(1998)
Eur. J. Pharmacol.
, vol.353
, pp. 191-206
-
-
Klitgaard, H.1
Matagne, A.2
Gobert, J.3
Wulfert, E.4
-
22
-
-
0034864170
-
Animal models used in the screening of antiepileptic drugs
-
Kupferberg H. Animal models used in the screening of antiepileptic drugs. Epilepsia. 42(Suppl. 4):2001;7-12.
-
(2001)
Epilepsia
, vol.42
, Issue.SUPPL. 4
, pp. 7-12
-
-
Kupferberg, H.1
-
23
-
-
0032473592
-
Effects of pentylenetetrazol kindling on glutamate receptor genes expression in the rat hippocampus
-
Lason W., Turchan J., Przewlocka B., Labuz D., Machelska H., Przewlocki R. Effects of pentylenetetrazol kindling on glutamate receptor genes expression in the rat hippocampus. Brain Res. 785:1998;355-358.
-
(1998)
Brain Res.
, vol.785
, pp. 355-358
-
-
Lason, W.1
Turchan, J.2
Przewlocka, B.3
Labuz, D.4
MacHelska, H.5
Przewlocki, R.6
-
24
-
-
0019979320
-
Comparative assay of anticonvulsant and toxic potencies of sixteen GABA mimetic drugs
-
Loscher W. Comparative assay of anticonvulsant and toxic potencies of sixteen GABA mimetic drugs. Neuropharmacology. 21:1982;803-810.
-
(1982)
Neuropharmacology
, vol.21
, pp. 803-810
-
-
Loscher, W.1
-
25
-
-
0023897574
-
Which animal models should be used in the search for new antiepileptic drugs? a proposal based on experimental and clinical considerations
-
Loscher W., Schmidt D. Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations. Epilepsy Res. 2:1988;145-181.
-
(1988)
Epilepsy Res.
, vol.2
, pp. 145-181
-
-
Loscher, W.1
Schmidt, D.2
-
26
-
-
0015394379
-
A permanent change in convulsive threshold in normal and brain-damaged rats with repeated small doses of pentylenetetrazole
-
Mason C.R., Cooper R.M. A permanent change in convulsive threshold in normal and brain-damaged rats with repeated small doses of pentylenetetrazole. Epilepsia. 13:1972;663-674.
-
(1972)
Epilepsia
, vol.13
, pp. 663-674
-
-
Mason, C.R.1
Cooper, R.M.2
-
28
-
-
0025861302
-
2+/calmodulin-dependent protein phosphorylation
-
2+/calmodulin- dependent protein phosphorylation. Neurosci. Res. 11:1991;146-153.
-
(1991)
Neurosci. Res.
, vol.11
, pp. 146-153
-
-
Onozuka, M.1
Tsujitani, M.2
-
29
-
-
0030013989
-
Intracellularly applied anti-P70 antibody blocks the induction of abnormal membrane properties by pentylenetetrazole in identified Euhadra neurons
-
Onozuka M., Watanabe K. Intracellularly applied anti-P70 antibody blocks the induction of abnormal membrane properties by pentylenetetrazole in identified Euhadra neurons. Brain Res. 716:1996;187-191.
-
(1996)
Brain Res.
, vol.716
, pp. 187-191
-
-
Onozuka, M.1
Watanabe, K.2
-
30
-
-
0017722337
-
Synaptic mechanism of pentylenetetrazole: Selectivity for chloride conductance
-
Pellmar T.C., Wilson W.A. Synaptic mechanism of pentylenetetrazole: selectivity for chloride conductance. Science. 197:1977;912-914.
-
(1977)
Science
, vol.197
, pp. 912-914
-
-
Pellmar, T.C.1
Wilson, W.A.2
-
31
-
-
0024371919
-
Anticonvulsant profile of an anesthetic steroid
-
Peterson S.L. Anticonvulsant profile of an anesthetic steroid. Neuropharmacology. 28:1989;877-879.
-
(1989)
Neuropharmacology
, vol.28
, pp. 877-879
-
-
Peterson, S.L.1
-
32
-
-
0021361095
-
Interactions of pentamethylenetetrazole and tetrazole analogues with the picrotoxinin site of the benzodiazepine-GABA receptor-ionophore complex
-
Ramanjaneyulu R., Ticku M.K. Interactions of pentamethylenetetrazole and tetrazole analogues with the picrotoxinin site of the benzodiazepine-GABA receptor-ionophore complex. Eur. J. Pharmacol. 98:1984;337-345.
-
(1984)
Eur. J. Pharmacol.
, vol.98
, pp. 337-345
-
-
Ramanjaneyulu, R.1
Ticku, M.K.2
-
33
-
-
0020528806
-
A benzodiazepine antagonist is an anticonvulsant in an animal model for limbic epilepsy
-
Robertson H.A., Riives M.L. A benzodiazepine antagonist is an anticonvulsant in an animal model for limbic epilepsy. Brain Res. 270:1983;380-382.
-
(1983)
Brain Res.
, vol.270
, pp. 380-382
-
-
Robertson, H.A.1
Riives, M.L.2
-
34
-
-
0029998502
-
Chronic and single administration of pentylenetetrazol modifies benzodiazepine receptor-binding: An autoradiographic study
-
Rocha L., Ackermann R.F., Engel J.J. Chronic and single administration of pentylenetetrazol modifies benzodiazepine receptor-binding: an autoradiographic study. Epilepsy Res. 24:1996;65-72.
-
(1996)
Epilepsy Res.
, vol.24
, pp. 65-72
-
-
Rocha, L.1
Ackermann, R.F.2
Engel, J.J.3
-
35
-
-
0031865123
-
Sensitivity and density of glutamate receptor subtypes in the hippocampal formation are altered in pentylenetetrazole-kindled rats
-
Schroeder H., Becker A., Hoellt V. Sensitivity and density of glutamate receptor subtypes in the hippocampal formation are altered in pentylenetetrazole-kindled rats. Exp. Brain Res. 120:1998;527-530.
-
(1998)
Exp. Brain Res.
, vol.120
, pp. 527-530
-
-
Schroeder, H.1
Becker, A.2
Hoellt, V.3
-
36
-
-
0030894743
-
Reversal of a selective decrease in hippocampal acetylcholine release, but not of the persistence of kindling, after discontinuation of long-term pentylenetetrazol administration in rats
-
Serra M., Dazzi L., Pisu M.G., Cagetti E., Biggio G. Reversal of a selective decrease in hippocampal acetylcholine release, but not of the persistence of kindling, after discontinuation of long-term pentylenetetrazol administration in rats. Brain Res. 751:1997;175-179.
-
(1997)
Brain Res.
, vol.751
, pp. 175-179
-
-
Serra, M.1
Dazzi, L.2
Pisu, M.G.3
Cagetti, E.4
Biggio, G.5
-
37
-
-
0030854871
-
Interactions of the neurosteroid dehydroepiandrosterone sulfate with the GABA(A) receptor complex reveals that it may act via the picrotoxin site
-
Sousa A., Ticku M.K. Interactions of the neurosteroid dehydroepiandrosterone sulfate with the GABA(A) receptor complex reveals that it may act via the picrotoxin site. J. Pharmacol. Exp. Ther. 282:1997;827-833.
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.282
, pp. 827-833
-
-
Sousa, A.1
Ticku, M.K.2
-
38
-
-
0031036809
-
Effect of pentylenetetrazol on the expression of tyrosine hydroxylase mRNA and norepinephrine and dopamine transporter mRNA
-
Szot P., White S.S., Veith R.C. Effect of pentylenetetrazol on the expression of tyrosine hydroxylase mRNA and norepinephrine and dopamine transporter mRNA. Brain Res. Mol. Brain Res. 44:1997;46-54.
-
(1997)
Brain Res. Mol. Brain Res.
, vol.44
, pp. 46-54
-
-
Szot, P.1
White, S.S.2
Veith, R.C.3
-
39
-
-
0032992977
-
Acute pentylenetetrazol injection reduces rat GABAA receptor mRNA levels and GABA stimulation of benzodiazepine binding with no effect on benzodiazepine binding site density
-
Walsh L.A., Li M., Zhao T.J., Chiu T.H., Rosenberg H.C. Acute pentylenetetrazol injection reduces rat GABAA receptor mRNA levels and GABA stimulation of benzodiazepine binding with no effect on benzodiazepine binding site density. J. Pharmacol. Exp. Ther. 289:1999;1626-1633.
-
(1999)
J. Pharmacol. Exp. Ther.
, vol.289
, pp. 1626-1633
-
-
Walsh, L.A.1
Li, M.2
Zhao, T.J.3
Chiu, T.H.4
Rosenberg, H.C.5
-
40
-
-
0034678524
-
Effects of differential modulation of mu-, delta- and kappa-opioid systems on bicuculline-induced convulsions in the mouse
-
Yajima Y., Narita M., Takahashi-Nakano Y., Misawa M., Nagase H., Mizoguchi H., Tseng L.F., Suzuki T. Effects of differential modulation of mu-, delta- and kappa-opioid systems on bicuculline-induced convulsions in the mouse. Brain Res. 862:2000;120-126.
-
(2000)
Brain Res.
, vol.862
, pp. 120-126
-
-
Yajima, Y.1
Narita, M.2
Takahashi-Nakano, Y.3
Misawa, M.4
Nagase, H.5
Mizoguchi, H.6
Tseng, L.F.7
Suzuki, T.8
-
41
-
-
0030423741
-
Chronic flumazenil alters GABAA subunit mRNA expression, translation product assembly and channel function in neuronal cultures
-
Zheng T.M., Caruncho H.J., Zhu W.J., Vicini S., Ikonomovic S. Chronic flumazenil alters GABAA subunit mRNA expression, translation product assembly and channel function in neuronal cultures. J. Pharmacol. Exp. Ther. 277:1996;525-533.
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.277
, pp. 525-533
-
-
Zheng, T.M.1
Caruncho, H.J.2
Zhu, W.J.3
Vicini, S.4
Ikonomovic, S.5
|