Polymers and permeation enhancers: Specialized components of mucoadhesives

Stamford Journal of Pharmaceutical Sciences

Volumn 4, Issue 1, 2011, Pages 91-95

  Alexander, Amit ^a   Ajazuddin, M ^a   Swarna, M ^a   Sharma, Mukesh ^a   Tripathi, D K ^a  

^a RUNGTA COLLEGE OF PHARMACEUTICAL SCIENCES AND RESEARCH   (India)

Author keywords

Bioadhesive property; Mucoadhesion; Mucoadhesive force; Mucoadhesive polymers

Indexed keywords

AGAROSE; ALGINIC ACID; ANIONIC SURFACTANT; CARBOMER; CARBOXYMETHYLCELLULOSE; CARRAGEENAN; CATIONIC SURFACTANT; CHITOSAN; COPOLYMER; ETHYLHEXYLACRYLATE; GELATIN; HYALURONIC ACID; HYDROXYETHYLCELLULOSE; HYDROXYETHYLMETHYLCELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE; MACROGOL; METHACRYLIC ACID; METHYLCELLULOSE; METHYLVINYLETHER; MUCOADHESIVE POLYMER; NONIONIC SURFACTANT; PECTIN; POLY 2 HYDROXYETHYLMETHACRYLATE; POLY(METHYL METHACRYLATE); POLYACRYLIC ACID; POLYALKYLCYANOACRYLATE; POLYCARBOPHIL; POLYMER; THIOLATED CARBOXYMETHYLCELLULOSE; UNCLASSIFIED DRUG;

COVALENT BOND; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; HYDROGEN BOND; REVIEW; STATIC ELECTRICITY;

EID: 84859079968     PISSN: 19997108     EISSN: None     Source Type: Journal    
DOI: 10.3329/sjps.v4i1.8878     Document Type: Review

References (31)

1. Abnawe SA. (2009) Mucoahesive Drug Delivery System. Pharmainfo.net. 1: 1-34.
2. Ahuja A, Khar RK, Ali J. (1997) Mucoadhesive drug delivery systems. Drug Develop Indus Pharm. 23:489-515.
3. Allen C, Maysinger D, Eisenberg A. (1999) Nano-engineering block copolymer aggregates for drug delivery, Col. Surf. B: Biointerfaces. 16: 3-27.
4. Andrew GP, Laverty TP, Jones DS. (2009) Mucoadhesive polymeric for controlled drugdelivery. European Journal of Pharmaceutics and Biopharmaceutics 71: 505-518.
5. Asane GS. (2007) Mucoadhesive Gastro Intestinal Drug Delivery System. Pharmainfo.net. 5:1-6.
6. Aungst A. (1994) Permeability and metabolism as barriers to transmucosal delivery of peptides and proteins, Drug Permeation Enhancement. Theory and Applications, Marcel Dekker, New York. 1: 323-343.
7. Benedetto DA, Shah DO, Kaufman HE. (1975) The instilled fluid dynamics and surfacechemistry of polymers in the preocular tear film. Investigative Ophthalmology. 14:887-902.
8. Bhatt JH. (2009) Designing And Evaluation of Mucoadhesive Microspheres of Metronidazole for Oral Controlled Drug Delivery. Pharmainfo.net. 2: 1-13.
9. Bhatt PP, Johnston TP. (1998). Evaluation of a mucoadhesivebuccal patch for delivery of peptides: In vitro screening of bioadhesion. Drug DevInd Pharm. 24:19-26.
10. Chickering D., Jacob J., Mathiowitz E. (1996) Poly (fumaric-cosebacic) microspheres as oral drug delivery systems. BiotechnolBioeng. 52:96-101.
11. Das Bibin K., Deepa P. (2009) Mucoadhesive Agents. B.Pharm. Project and review articles. 1: 1-29.
12. Hagerstrom H. (2006) Polymer gels as Pharmaceutical Dosage Forms, Comprehensive Summaries of Uppsala Dissertationsfrom the Faculty of Pharmacy 293. 1: 1-17.
13. Hunt G, Kearney P, Kellaway, IW. (1987) Mucoadhesive polymers in drug delivery systems. Drug Delivery System: Fundamental and Techniqes. Elis Horwood Chichester. 2:180-185.
14. Kast CE, Guggi D, Langoth N, Bernkop-Schnürch A. (2003) Pharm. Res. 20: 931-936.
15. Lee JW, Park JH, Robinson JR. (2000) Bioadhesive-based dosage forms: The next generation J. Pharm. Sci. 89: 850-866.
16. Leitner VM, Guggi D, Bernkop-Schnürch A. (2003) Central Eur. Symp. Pharm. Technology, Ljubljana, Slovenia. 1: 1-12.
17. Punitha S, Girish Y. (2010) Polymers in mucoadhesivebuccal drug delivery system. International Journal of Research and Pharmaceutical Sciences.1:170-186.
18. Rajput GC, Majmudar FD, Patel JK, Patel KN, Thakor RS, Patel BP, Rajgor NB. (2010) Stomach Specific Mucoadhesivemicrosphere as a controlled drug delivery system, Systematic Reviews In Pharmacy.1:70-78.
19. Rathore K. (2009) Formulation and Evaluation of Mucoadhesive Drug Delivery systems. Pharma Times. 35:29-35.
20. Rossi S, Bonferoni MC, Ferrari F, Caramella C. (1999) Drug release and washability of mucoadhesive gels based on sodium carboxymethylcellulose and polyacrylic acid. Pharmaceutical development and technology. 4: 55-63.
21. Roy SK, Prabhakar B. (2010) Bioadhesive Polymeric Platforms for TransmucosalDrug Delivery Systems. Tropical Journal of Pharmaceutical Research. 9:91-104.
22. Saviae R, Eisenberg LLA, Maysinger D. (2003) Micellarnano containers distribute to defined cytoplasmic organelles. Tropical Journal of Science. 300: 615-618.
23. Schipper NGM, Varum KM, Artursson P. (2004) Chitosans as absorption enhancers for poorly absorbable drugs: influence of the molecular weight and degree of ace-tylation on drug transport across human intestinal epithelium (Caco-2) cells. Pharm. Res. 21: 344-353.
24. Schnurch AB. (2005) Thiomers: A new generation of mucoadhesive polymers. Advanced Drug Delivery Reviews. Elsevier. 57: 1569-1582.
25. Semalty A. (2006) Mucoadhesive Polymers. Pharmainfo. net. 4:1-10.
26. Sharma HK, Sarangi B, PradhanSiba P. (2009) Preparation and in-vitro evaluation of mucoadhesivemicrobeads containing Timolol Maleate using mucoadhesive substances of Dilleniaindica L. Arch Pharmaceutical Sciences & Research. 1:181-188.
27. Shojaei AH. (1998) Buccal mucosa as a route for systemic drug delivery: A review. J. Pharm. Pharmaceut. Sci. 1: 15-30.
28. Smart JD. (2005) The basics and underlying mechanisms of mucoadhesion. Science Direct. 57:1556-1568.
29. Thielmann F, Naderi M, Khutoryanskiy V, Khutoryanskaya O. (2007) Mucoadhesivehydrogel films based on blends of poly(acrylic acid) and methylcellulose. Available at: http://www.aapsj.org/abstracts/ NBC_2007/NBC07-000679.PDF.
30. Valenta C. (2005) The use of mucoadhesive polymers in vaginal delivery. Advanced Drug Delivery Reviews. Elsevier. 57:1692-1712.
31. Yadav VK, Gupta AB, Kumar R, Yadav JS, Kumar B. (2010) Mucoadhesive Polymers: Means of Improving the Mucoadhesive Properties of Drug Delivery System. J. Chem. Pharm. Res. 2:418-432.