메뉴 건너뛰기




Volumn 67 A, Issue 4, 2012, Pages 366-375

Gene categories differentially expressed in C. elegans Age-1 Mutants of extraordinary longevity: New insights from novel data-mining procedures

Author keywords

Genetics; GO analysis; Longevity; Microarray; Transcription

Indexed keywords

CAENORHABDITIS ELEGANS;

EID: 84859055224     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glr186     Document Type: Article
Times cited : (8)

References (50)
  • 1
    • 0035992248 scopus 로고    scopus 로고
    • Empirical Bayes methods and false discovery rates for microarrays
    • DOI 10.1002/gepi.1124
    • Efron B, Tibshirani R. Empirical Bayes methods and false discovery rates for microarrays. Genet Epidemiol. 2002;23:70-86. (Pubitemid 34743158)
    • (2002) Genetic Epidemiology , vol.23 , Issue.1 , pp. 70-86
    • Efron, B.1    Tibshirani, R.2
  • 2
    • 0000847978 scopus 로고    scopus 로고
    • Gene-expression profile of the ageing brain in mice
    • DOI 10.1038/77046
    • Lee CK, Weindruch R, Prolla TA. Gene-expression profile of the ageing brain in mice. Nat Genet. 2000;25:294-297. (Pubitemid 30437315)
    • (2000) Nature Genetics , vol.25 , Issue.3 , pp. 294-297
    • Lee, C.-K.1    Weindruch, R.2    Prolla, T.A.3
  • 3
    • 0033610079 scopus 로고    scopus 로고
    • Gene expression profile of aging and its retardation by caloric restriction
    • DOI 10.1126/science.285.5432.1390
    • Lee CK, Klopp RG, Weindruch R, Prolla TA. Gene expression profile of aging and its retardation by caloric restriction. Science. 1999;285:1390-1393. (Pubitemid 29411668)
    • (1999) Science , vol.285 , Issue.5432 , pp. 1390-1393
    • Lee, C.-K.1    Klopp, R.G.2    Weindruch, R.3    Prolla, T.A.4
  • 5
    • 33846858644 scopus 로고    scopus 로고
    • Candidate genes affecting Drosophila life span identified by integrating microarray gene expression analysis and QTL mapping
    • DOI 10.1016/j.mad.2006.12.003, PII S0047637406002806
    • Lai CQ, Parnell LD, Lyman RF, Ordovas JM, Mackay TF. Candidate genes affecting Drosophila life span identified by integrating microarray gene expression analysis and QTL mapping. Mech Ageing Dev. 2007;128:237-249. (Pubitemid 46227542)
    • (2007) Mechanisms of Ageing and Development , vol.128 , Issue.3 , pp. 237-249
    • Lai, C.-Q.1    Parnell, L.D.2    Lyman, R.F.3    Ordovas, J.M.4    Mackay, T.F.C.5
  • 7
    • 36448969497 scopus 로고    scopus 로고
    • Evolutionary conservation of regulated longevity assurance mechanisms
    • McElwee JJ, Schuster E, Blanc E, et al. Evolutionary conservation of regulated longevity assurance mechanisms. Genome Biol. 2007;8:R132.
    • (2007) Genome Biol , vol.8
    • McElwee, J.J.1    Schuster, E.2    Blanc, E.3
  • 8
    • 7244238167 scopus 로고    scopus 로고
    • Shared transcriptional signature in Caenorhabditis elegans dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance
    • DOI 10.1074/jbc.M406207200
    • McElwee JJ, Schuster E, Blanc E, Thomas JH, Gems D. Shared transcriptional signature in Caenorhabditis elegans dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance. J Biol Chem. 2004;279:44533-44543. (Pubitemid 39430860)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.43 , pp. 44533-44543
    • McElwee, J.J.1    Schuster, E.2    Blanc, E.3    Thomas, J.H.4    Gems, D.5
  • 9
    • 34249748303 scopus 로고    scopus 로고
    • Common aging pathways in worms, flies, mice and humans
    • DOI 10.1242/jeb.004887
    • Kim SK. Common aging pathways in worms, flies, mice and humans. J Exp Biol. 2007;210:1607-1612. (Pubitemid 46841966)
    • (2007) Journal of Experimental Biology , vol.210 , Issue.9 , pp. 1607-1612
    • Kim, S.K.1
  • 11
    • 0042092531 scopus 로고    scopus 로고
    • Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
    • Murphy CT, McCarroll SA, Bargmann CI, et al. Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature. 2003;424:277-283.
    • (2003) Nature , vol.424 , pp. 277-283
    • Murphy, C.T.1    McCarroll, S.A.2    Bargmann, C.I.3
  • 12
    • 38349093613 scopus 로고    scopus 로고
    • Remarkable longevity and stress resistance of nematode PI3K-null mutants
    • Ayyadevara S, Alla R, Thaden JJ, Shmookler Reis RJ. Remarkable longevity and stress resistance of nematode PI3K-null mutants. Aging Cell. 2008;7:13-22.
    • (2008) Aging Cell , vol.7 , pp. 13-22
    • Ayyadevara, S.1    Alla, R.2    Thaden, J.J.3    Shmookler Reis, R.J.4
  • 13
    • 79959568125 scopus 로고    scopus 로고
    • Modulation of lipid biosynthesis contributes to stress resistance and longevity of C. elegans mutants
    • Shmookler Reis RJ, Xu L, Lee H, et al. Modulation of lipid biosynthesis contributes to stress resistance and longevity of C. elegans mutants. Aging (Albany NY). 2011;3:125-147.
    • (2011) Aging (Albany NY) , vol.3 , pp. 125-147
    • Shmookler Reis, R.J.1    Xu, L.2    Lee, H.3
  • 15
    • 0035917440 scopus 로고    scopus 로고
    • A conserved regulatory system for aging
    • DOI 10.1016/S0092-8674(01)00306-3
    • Kenyon C. A conserved regulatory system for aging. Cell. 2001;105:165-168. (Pubitemid 32429505)
    • (2001) Cell , vol.105 , Issue.2 , pp. 165-168
    • Kenyon, C.1
  • 16
    • 66149147947 scopus 로고    scopus 로고
    • Positive feedback between transcriptional and kinase suppression in nematodes with extraordinary longevity and stress resistance
    • Tazearslan C, Ayyadevara S, Bharill P, Shmookler Reis RJ. Positive feedback between transcriptional and kinase suppression in nematodes with extraordinary longevity and stress resistance. PLoS Genet. 2009;5:e1000452.
    • (2009) PLoS Genet , vol.5
    • Tazearslan, C.1    Ayyadevara, S.2    Bharill, P.3    Shmookler Reis, R.J.4
  • 18
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang da W, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc. 2009;4:44-57.
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 19
    • 1342294092 scopus 로고    scopus 로고
    • Normalization for cDNA microarray data: A robust composite method addressing single and multiple slide systematic variation
    • Yang YH, Dudoit S, Luu P, et al. Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation. Nucleic Acids Res. 2002;30:e15.
    • (2002) Nucleic Acids Res , vol.30
    • Yang, Y.H.1    Dudoit, S.2    Luu, P.3
  • 20
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical Bayes methods for assessing differential expression in microarray experiments
    • Article 3 doi: 10.2202/1544-6115.1027
    • Smyth GK. Linear models and empirical Bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol. 2004;3(1):Article 3. doi: 10.2202/1544-6115.1027
    • (2004) Stat Appl Genet Mol Biol , vol.3 , Issue.1
    • Smyth, G.K.1
  • 21
    • 0348143180 scopus 로고    scopus 로고
    • A random variance model for detection of differential gene expression in small microarray experiments
    • DOI 10.1093/bioinformatics/btg345
    • Wright GW, Simon RM. A random variance model for detection of differential gene expression in small microarray experiments. Bioinformatics. 2003;19:2448-2455. (Pubitemid 38016644)
    • (2003) Bioinformatics , vol.19 , Issue.18 , pp. 2448-2455
    • Wright, G.W.1    Simon, R.M.2
  • 22
    • 4444257989 scopus 로고    scopus 로고
    • Multiple-testing strategy for analyzing cDNA array data on gene expression
    • DOI 10.1111/j.0006-341X.2004.00228.x
    • Delongchamp RR, Bowyer JF, Chen JJ, Kodell RR. Multiple-testing strategy for analyzing cDNA array data on gene expression. Biometrics. 2004;60:774-782. (Pubitemid 39181123)
    • (2004) Biometrics , vol.60 , Issue.3 , pp. 774-782
    • Delongchamp, R.R.1    Bowyer, J.F.2    Chen, J.J.3    Kodell, R.L.4
  • 23
    • 0000992959 scopus 로고
    • Plots of p-values to evaluate many tests simultaneously
    • Schweder T, Spjotvoll E. Plots of p-values to evaluate many tests simultaneously. Biometrika. 1982;69:502.
    • (1982) Biometrika , vol.69 , pp. 502
    • Schweder, T.1    Spjotvoll, E.2
  • 25
    • 33947301898 scopus 로고    scopus 로고
    • A method for computing the overall statistical significance of a treatment effect among a group of genes
    • Delongchamp R, Lee T, Velasco C. A method for computing the overall statistical significance of a treatment effect among a group of genes. BMC Bioinformatics. 2006;7(suppl 2):S11.
    • (2006) BMC Bioinformatics , vol.7 , Issue.SUPPL. 2
    • Delongchamp, R.1    Lee, T.2    Velasco, C.3
  • 26
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc B. 1995;57:289-300.
    • (1995) J R Stat Soc B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 28
    • 0242441598 scopus 로고    scopus 로고
    • 3 at endomembranes is triggered by receptor endocytosis
    • DOI 10.1038/ncb1054
    • Sato M, Ueda Y, Takagi T, Umezawa Y. Production of PtdInsP3 at endomembranes is triggered by receptor endocytosis. Nat Cell Biol. 2003;5:1016-1022. (Pubitemid 37406916)
    • (2003) Nature Cell Biology , vol.5 , Issue.11 , pp. 1016-1022
    • Sato, M.1    Ueda, Y.2    Takagi, T.3    Umezawa, Y.4
  • 30
    • 77957675740 scopus 로고    scopus 로고
    • Regulation of C. elegans fat uptake and storage by acyl-CoA synthase-3 is dependent on NR5A family nuclear hormone receptor nhr-25
    • Mullaney BC, Blind RD, Lemieux GA, et al. Regulation of C. elegans fat uptake and storage by acyl-CoA synthase-3 is dependent on NR5A family nuclear hormone receptor nhr-25. Cell Metab. 2010;12:398-410.
    • (2010) Cell Metab , vol.12 , pp. 398-410
    • Mullaney, B.C.1    Blind, R.D.2    Lemieux, G.A.3
  • 31
    • 0031574450 scopus 로고    scopus 로고
    • Targeted gene disruption of the Caenorhabditis elegans L-isoaspartyl protein repair methyltransferase impairs survival of dauer stage nematodes
    • DOI 10.1006/abbi.1997.0362
    • Kagan RM, Niewmierzycka A, Clarke S. Targeted gene disruption of the Caenorhabditis elegans L-isoaspartyl protein repair methyltransferase impairs survival of dauer stage nematodes. Arch Biochem Biophys. 1997;348:320-328. (Pubitemid 28028483)
    • (1997) Archives of Biochemistry and Biophysics , vol.348 , Issue.2 , pp. 320-328
    • Kagan, R.M.1    Niewmierzycka, A.2    Clarke, S.3
  • 32
    • 77954660029 scopus 로고    scopus 로고
    • Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans
    • Greer EL, Maures TJ, Hauswirth AG, et al. Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans. Nature. 2010;466:383-387.
    • (2010) Nature , vol.466 , pp. 383-387
    • Greer, E.L.1    Maures, T.J.2    Hauswirth, A.G.3
  • 33
    • 79952442449 scopus 로고    scopus 로고
    • Involvement of heme oxygenase-1 induction via Nrf2/ARE activation in protection against H2O2-induced PC12 cell death by a metabolite of sesamin contained in sesame seeds
    • Hamada N, Tanaka A, Fujita Y, et al. Involvement of heme oxygenase-1 induction via Nrf2/ARE activation in protection against H2O2-induced PC12 cell death by a metabolite of sesamin contained in sesame seeds. Bioorg Med Chem. 2011;19:1959-1965.
    • (2011) Bioorg Med Chem , vol.19 , pp. 1959-1965
    • Hamada, N.1    Tanaka, A.2    Fujita, Y.3
  • 35
    • 55449120240 scopus 로고    scopus 로고
    • A TRPV channel modulates C. elegans neurosecretion, larval starvation survival, and adult lifespan
    • Lee BH, Ashrafi K. A TRPV channel modulates C. elegans neurosecretion, larval starvation survival, and adult lifespan. PLoS Genet. 2008;4:e1000213.
    • (2008) PLoS Genet , vol.4
    • Lee, B.H.1    Ashrafi, K.2
  • 36
    • 34948881208 scopus 로고    scopus 로고
    • Mitochondria: A hub of redox activities and cellular distress control
    • DOI 10.1007/s11010-007-9520-8
    • Kakkar P, Singh BK. Mitochondria: a hub of redox activities and cellular distress control. Mol Cell Biochem. 2007;305:235-253. (Pubitemid 47517185)
    • (2007) Molecular and Cellular Biochemistry , vol.305 , Issue.1-2 , pp. 235-253
    • Kakkar, P.1    Singh, B.K.2
  • 37
    • 77950980708 scopus 로고    scopus 로고
    • Age-dependent axonal expression of potassium channel proteins during development in mouse hippocampus
    • Pruss H, Grosse G, Brunk I, Veh RW, Ahnert-Hilger G. Age-dependent axonal expression of potassium channel proteins during development in mouse hippocampus. Histochem Cell Biol. 2010;133:301-312.
    • (2010) Histochem Cell Biol , vol.133 , pp. 301-312
    • Pruss, H.1    Grosse, G.2    Brunk, I.3    Veh, R.W.4    Ahnert-Hilger, G.5
  • 38
    • 49449088093 scopus 로고    scopus 로고
    • Kv1.3 gene-targeted deletion alters longevity and reduces adiposity by increasing locomotion and metabolism in melanocortin-4 receptor-null mice
    • Tucker K, Overton JM, Fadool DA. Kv1.3 gene-targeted deletion alters longevity and reduces adiposity by increasing locomotion and metabolism in melanocortin-4 receptor-null mice. Int J Obes (Lond). 2008;32:1222-1232.
    • (2008) Int J Obes (Lond) , vol.32 , pp. 1222-1232
    • Tucker, K.1    Overton, J.M.2    Fadool, D.A.3
  • 39
    • 34548552633 scopus 로고    scopus 로고
    • Zinc dyshomeostasis, ageing and neurodegeneration: Implications of A2M and inflammatory gene polymorphisms
    • The Multifaceted Aspects of Alzheimer's Disease: From Social to Molecular Problems
    • Mocchegiani E, Malavolta M. Zinc dyshomeostasis, ageing and neurodegeneration: implications of A2M and inflammatory gene polymorphisms. J Alzheimers Dis. 2007;12:101-109. (Pubitemid 47396309)
    • (2007) Journal of Alzheimer's Disease , vol.12 , Issue.1 , pp. 101-109
    • Mocchegiani, E.1    Malavolta, M.2
  • 40
    • 0034645038 scopus 로고    scopus 로고
    • Mechanism of metabolic control. Target of rapamycin signaling links nitrogen quality to the activity of the Rtg1 and Rtg3 transcription factors
    • Komeili A, Wedaman KP, O'Shea EK, Powers T. Mechanism of metabolic control. Target of rapamycin signaling links nitrogen quality to the activity of the Rtg1 and Rtg3 transcription factors. J Cell Biol. 2000;151:863-878.
    • (2000) J Cell Biol , vol.151 , pp. 863-878
    • Komeili, A.1    Wedaman, K.P.2    O'Shea, E.K.3    Powers, T.4
  • 41
    • 0036678146 scopus 로고    scopus 로고
    • The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans
    • Morley JF, Brignull HR, Weyers JJ, Morimoto RI. The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans. Proc Natl Acad Sci USA. 2002;99:10417-10422.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 10417-10422
    • Morley, J.F.1    Brignull, H.R.2    Weyers, J.J.3    Morimoto, R.I.4
  • 42
    • 70349266064 scopus 로고    scopus 로고
    • Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging
    • Ben-Zvi A, Miller EA, Morimoto RI. Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging. Proc Natl Acad Sci USA. 2009;106:14914-14919.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 14914-14919
    • Ben-Zvi, A.1    Miller, E.A.2    Morimoto, R.I.3
  • 45
    • 23044445756 scopus 로고    scopus 로고
    • A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans
    • DOI 10.1038/ng1608
    • Rea SL, Wu D, Cypser JR, Vaupel JW, Johnson TE. A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans. Nat Genet. 2005;37:894-898. (Pubitemid 41077118)
    • (2005) Nature Genetics , vol.37 , Issue.8 , pp. 894-898
    • Rea, S.L.1    Wu, D.2    Cypser, J.R.3    Vaupel, J.W.4    Johnson, T.E.5
  • 47
    • 77953091249 scopus 로고    scopus 로고
    • Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity
    • Henis-Korenblit S, Zhang P, Hansen M, et al. Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity. Proc Natl Acad Sci USA. 2010;107:9730-9735.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 9730-9735
    • Henis-Korenblit, S.1    Zhang, P.2    Hansen, M.3
  • 48
    • 33846423520 scopus 로고    scopus 로고
    • Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans
    • DOI 10.1111/j.1474-9726.2006.00267.x
    • Hansen M, Taubert S, Crawford D, Libina N, Lee SJ, Kenyon C. Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans. Aging Cell. 2007;6:95-110. (Pubitemid 46140143)
    • (2007) Aging Cell , vol.6 , Issue.1 , pp. 95-110
    • Hansen, M.1    Taubert, S.2    Crawford, D.3    Libina, N.4    Lee, S.-J.5    Kenyon, C.6
  • 49
    • 12344309431 scopus 로고    scopus 로고
    • Broad spectrum detoxification: The major longevity assurance process regulated by insulin/IGF-1 signaling?
    • DOI 10.1016/j.mad.2004.09.001, PII S0047637404001745
    • Gems D, McElwee JJ. Broad spectrum detoxification: the major longevity assurance process regulated by insulin/IGF-1 signaling? Mech Ageing Dev. 2005;126:381-387. (Pubitemid 40128171)
    • (2005) Mechanisms of Ageing and Development , vol.126 , Issue.3 , pp. 381-387
    • Gems, D.1    McElwee, J.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.