A high-content subtractive screen for selecting small molecules affecting internalization of GPCRs

Journal of Biomolecular Screening

Volumn 17, Issue 3, 2012, Pages 379-385

  Kwon, Yong Jun ^a,b   Lee, Weontae ^b   Genovesio, Auguste ^a   Emans, Neil ^c  

^a Institute Pasteur Korea   (South Korea)

^b Yonsei University   (South Korea)

^c DSI CSIR Nanotechnology Innovation Centre   (South Africa)

Author keywords

cell based assay; chemical biology; endocytosis; G protein coupled receptor; High content screening; image analysis

Indexed keywords

ADENOSINE RECEPTOR 1; ADENOSINE RECEPTOR 3; ENDOTHELIN 1; G PROTEIN COUPLED RECEPTOR; KAPPA OPIATE RECEPTOR; MU OPIATE RECEPTOR; MUSCARINIC ACETYLCHOLINE RECEPTOR 2; MUSCARINIC RECEPTOR; TRANSFERRIN; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; EMBRYO; ENDOCYTOSIS; HUMAN; HUMAN CELL; INTERNALIZATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

BIOLOGICAL ASSAY; ENDOCYTOSIS; GENOMICS; HEK293 CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; PROTEIN KINASE INHIBITORS; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; SMALL MOLECULE LIBRARIES; TRANSFERRIN;

EID: 84859045490     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057111427347     Document Type: Article

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