Continuous-flow left ventricular assist device support in patients with advanced heart failure: Points of interest for the daily management

European Journal of Heart Failure

Volumn 14, Issue 4, 2012, Pages 351-356

  Felix, S E A ^a   Martina, J R ^a   Kirkels, J H ^a   Klpping, C ^a   Nathoe, H ^a   Sukkel, E ^a   Hulstein, N ^a   Ramjankhan, F Z ^a   Doevendans, P A F M ^a   Lahpor, J R ^a   De Jonge, Nicholaas ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Complication; End stage heart failure; Left ventricular assist device; Mechanical circulatory support

Indexed keywords

AMIODARONE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; HEPARIN; IMMUNOSUPPRESSIVE AGENT; QUINIDINE;

ADULT; ANTICOAGULANT THERAPY; APHASIA; ASYSTOLE; BLEEDING; BLOODSTREAM INFECTION; BRAIN ISCHEMIA; CARDIAC RESYNCHRONIZATION THERAPY; CARDIAC RESYNCHRONIZATION THERAPY DEVICE; CARDIOGENIC SHOCK; CARDIOMYOPATHY; CASE REPORT; CEREBROVASCULAR ACCIDENT; CONTINUOUS PROCESS; DEFIBRILLATOR; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAM; ENDOCARDITIS; HEART FAILURE; HEART VALVE; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; HEMIPARESIS; HEMODYNAMIC PARAMETERS; HUMAN; HYPERTENSION; INTRACARDIAC THROMBOSIS; LEFT VENTRICULAR ASSIST DEVICE; LOWER RESPIRATORY TRACT INFECTION; MALE; MYOCARDITIS; PATHOLOGY; PERCUTANEOUS CORONARY INTERVENTION; PHYSIOLOGY; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; PROSTHESIS FAILURE; REVIEW; VASCULAR DISEASE; VON WILLEBRAND DISEASE;

ADULT; ARRHYTHMIAS, CARDIAC; DISEASE PROGRESSION; HEART FAILURE; HEART-ASSIST DEVICES; HEMODYNAMICS; HEMORRHAGE; HUMANS; IATROGENIC DISEASE; INFECTION; MALE; MIDDLE AGED; YOUNG ADULT;

EID: 84859043991     PISSN: 13889842     EISSN: 18790844     Source Type: Journal    
DOI: 10.1093/eurjhf/hfs012     Document Type: Review

References (46)

1. Rose EA, Gelijns AC, Moskowitz AJ, Heitjan DF, Stevenson LW, Dembitsky W, Long JW, Ascheim DD, Tierney AR, Levitan RG, Watson JT, Meier P, Ronan NS, Shapiro PA, Lazar RM, Miller LW, Gupta L, Frazier OH, Desvigne-Nickens P, Oz MC, Poirier VL; Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure (REMATCH) Study Group. Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med 2001;345:1435-1443.
2. Slaughter MS, Rogers JG, Milano CA, Russell SD, Conte JV, Feldman D, Sun B, Tatooles AJ, Delgado RM 3rd, Long JW, Wozniak TC, Ghumman W, Farrar DJ, Frazier OH; HeartMate II Investigators. Advanced heart failure treated with continuous-flow left ventricular assist device. N Engl J Med 2009;361:2241-2251.
3. Miller LW, Pagani FD, Russell SD, John R, Boyle AJ, Aaronson KD, Conte JV, Naka Y, Mancini D, Delgado RM, MacGillivray TE, Farrar DJ, Frazier OH; Heart-Mate II Clinical Investigators. Use of a continuous-flow device in patients awaiting heart transplantation. N Engl J Med 2007;357:885-896.
4. Pagani FD, Miller LW, Russell SD, Aaronson KD, John R, Boyle AJ, Conte JV, Bogaev RC, MacGillivray TE, Naka Y, Mancini D, Massey HT, Chen L, Klodell CT, Aranda JM, Moazami N, Ewald GA, Farrar DJ, Frazier OH; HeartMate II Investigators. Extended mechanical circulatory support with a continuous-flow rotary left ventricular assist device. J Am Coll Cardiol 2009;54:312-321.
5. Alba AC, McDonald M, Rao V, Ross HJ, Delgado DH. The effect of ventricular assist devices on long-term post-transplant outcomes: a systematic review of observational studies. Eur J Heart Fail 2011;13:785-795.
6. Pamboukian SV, Tallaj JA, Brown RN, Holman WL, Blood M, George JF, Costanzo MR, Cadeiras M, Smallfield MC, McGiffin DC, Kirklin JK. Improvement in 2-year survival for ventricular assist device patients after implementation of an intensive surveillance protocol. J Heart Lung Transplant 2011;30:879-887.
7. Kirklin JK, Naftel DC, Kormos RL, Stevenson LW, Pagani FD, Miller MA, Ulisney KL, Baldwin JT, Young JB. Third INTERMACS Annual Report: the evolution of destination therapy in the United States. J Heart Lung Transplant 2011;30: 115-123.
8. Haft J, Armstrong W, Dyke DB, Aaronson KD, Koelling TM, Farrar DJ, Pagani FD. Hemodynamic and exercise performance with pulsatile and continuous-flow left ventricular assist devices. Circulation 2007;116(11 Suppl):I8-I15.
9. Lund LH, Matthews J, Aaronson K. Patient selection for left ventricular assist devices. Eur J Heart Fail 2010;12:434-443.
10. Slaughter MS, Pagani FD, Rogers JG, Miller LW, Sun B, Russell SD, Starling RC, Chen L, Boyle AJ, Chillcott S, Adamson RM, Blood MS, Camacho MT, Idrissi KA, Petty M, Sobieski M, Wright S, Myers TJ, Farrar DJ; HeartMate II Clinical Investigators. Clinical management of continuous-flow left ventricular assist devices in advanced heart failure. J Heart Lung Transplant 2010;29(4 Suppl): S1-S39.
11. Warkentin TE, Greinacher A, Koster A. Heparin-induced thrombocytopenia in patients with ventricular assist devices: are new prevention strategies required? Ann Thorac Surg 2009;87:1633-1640.
12. Crow S, Chen D, Milano C, Thomas W, Joyce L, Piacentino V 3rd, Sharma R, Wu J, Arepally G, Bowles D, Rogers J, Villamizar-Ortiz N. Acquired von Willebrand syndrome in continuous-flow ventricular assist device recipients. Ann Thorac Surg 2010;90:1263-1269.
13. Crow S, Milano C, Joyce L, Chen D, Arepally G, Bowles D, Thomas W, Ortiz NV. Comparative analysis of von Willebrand factor profiles in pulsatile and continuous left ventricular assist device recipients. ASAIO J 2010;56:441-445.
14. Meyer AL, Malehsa D, Bara C, Budde U, Slaughter MS, Haverich A, Strueber M. Acquired von Willebrand syndrome in patients with an axial flow left ventricular assist device. Circ Heart Fail 2010;3:675-681.
15. Spanier T, Oz M, Levin H, Weinberg A, Stamatis K, Stern D, Rose E, Schmidt AM. Activation of coagulation and fibrinolytic pathways in patients with left ventricular assist devices. J Thorac Cardiovasc Surg 1996;112:1090-1097.
16. Uriel N, Pak SW, Jorde UP, Jude B, Susen S, Vincentelli A, Ennezat PV, Cappleman S, Naka Y, Mancini D. Acquired von Willebrand syndrome after continuous-flow mechanical device support contributes to a high prevalence of bleeding during long-term support and at the time of transplantation. J Am Coll Cardiol 2010;56:1207-1213.
17. Heilmann C, Geisen U, Beyersdorf F, Nakamura L, Benk C, Berchtold-Herz M, Trummer G, Schlensak C, Zieger B. Acquired von Willebrand syndrome in patients with ventricular assist device or total artificial heart. Thromb Haemost 2010;103:962-967.
18. Geisen U, Heilmann C, Beyersdorf F, Benk C, Berchtold-Herz M, Schlensak C, Budde U, Zieger B. Nonsurgical bleeding in patients with ventricular assist devices could be explained by acquired von Willebrand disease. Eur J Cardiothorac Surg 2008;33:679-684.
19. Demirozu ZT, Radovancevic R, Hochman LF, Gregoric ID, Letsou GV, Kar B, Bogaev RC, Frazier OH. Arteriovenous malformation and gastrointestinal bleeding in patients with the HeartMate II left ventricular assist device. J Heart Lung Transplant 2011;30:849-853.
20. Potapov EV, Stepanenko A, Krabatsch T, Hetzer R. Managing long-term complications of left ventricular assist device therapy. Curr Opin Cardiol 2011;26:237-244.
21. Boyle AJ, Russell SD, Teuteberg JJ, Slaughter MS, Moazami N, Pagani FD, Frazier OH, Heatley G, Farrar DJ, John R. Low thromboembolism and pump thrombosis with the HeartMate II left ventricular assist device: analysis of outpatient anti-coagulation. J Heart Lung Transplant 2009;28:881-887.
22. John R, Kamdar F, Liao K, Colvin-Adams M, Miller L, Joyce L, Boyle A. Low thromboembolic risk for patients with the HeartMate II left ventricular assist device. J Thorac Cardiovasc Surg 2008;136:1318-23.
23. Strüber M, Sander K, Lahpor J, Ahn H, Litzler PY, Drakos SG, Musumeci F, Schlensak C, Friedrich I, Gustafsson R, Oertel F, Leprince P. HeartMate II left ventricular assist device; early European experience. Eur J Cardiothorac Surg 2008;34: 289-294.
24. John R, Kamdar F, Liao K, Colvin-Adams M, Boyle A, Joyce L. Improved survival and decreasing incidence of adverse events with the HeartMate II left ventricular assist device as bridge-to-transplant therapy. Ann Thorac Surg 2008;86:1227-345.
25. Slaughter MS. Hematologic effects of continuous flow left ventricular assist devices. J Cardiovasc Transl Res 2010;3:618-624.
26. Heilmann C, Geisen U, Benk C, Berchtold-Herz M, Trummer G, Schlensak C, Zieger B, Beyersdorf F. Haemolysis in patients with ventricular assist devices: major differences between systems. Eur J Cardiothorac Surg 2009;36:580-584.
27. Hannan MM, Husain S, Mattner F, Danziger-Isakov L, Drew RJ, Corey GR, Schueler S, Holman WL, Lawler LP, Gordon SM, Mahon NG, Herre JM, Gould K, Montoya JG, Padera RF, Kormos RL, Conte JV, Mooney ML; International Society for Heart and Lung Transplantation. Working formulation for the standardization of definitions of infections in patients using ventricular assist devices. J Heart Lung Transplant 2011;30:375-384.
28. Schaffer JM, Allen JG, Weiss ES, Arnaoutakis GJ, Patel ND, Russell SD, Shah AS, Conte JV. Infectious complications after pulsatile-flow and continuous-flow left ventricular assist device implantation. J Heart Lung Transplant 2011;30:164-174.
29. Strueber M, O'Driscoll G, Jansz P, Khaghani A, Levy WC, Wieselthaler GM; HeartWare Investigators. Multicenter evaluation of an intrapericardial left ventricular assist system. J Am Coll Cardiol 2011;57:1375-2382.
30. Esmon CT. Crosstalk between inflammation and thrombosis. Maturitas 2008;61: 122-131.
31. Birks EJ, Tansley PD, Yacoub MH, Bowles CT, Hipkin M, Hardy J, Banner NR, Khaghani A. Incidence and clinical management of life-threatening left ventricular assist device failure. J Heart Lung Transplant 2004;23:964-969.
32. Slaughter MS. Long-term continuous flow left ventricular assist device support and end-organ function: prospects for destination therapy. J Card Surg 2010;25: 490-494.
33. Slaughter MS, Tsui SS, El-Banayosy A, Sun BC, Kormos RL, Mueller DK, Massey HT, Icenogle TB, Farrar DJ, Hill JD; IVAD Study Group. Results of a multicenter clinical trial with the Thoratec Implantable Ventricular Assist Device. J Thorac Cardiovasc Surg 2007;133:1573-1580.
34. John R, Lee S, Eckman P, Liao K. Right ventricular failure-a continuing problem in patients with left ventricular assist device support. J Cardiovasc Transl Res 2010;3: 604-611.
35. Lee S, Kamdar F, Madlon-Kay R, Boyle A, Colvin-Adams M, Pritzker M, John R. Effects of the HeartMate II continuous-flow left ventricular assist device on right ventricular function. J Heart Lung Transplant 2010;29:209-215.
36. Kormos RL, Teuteberg JJ, Pagani FD, Russell SD, John R, Miller LW, Massey T, Milano CA, Moazami N, Sundareswaran KS, Farrar DJ; HeartMate II Clinical Investigators. Right ventricular failure in patients with the HeartMate II continuous-flow left ventricular assist device: incidence, risk factors, and effect on outcomes. J Thorac Cardiovasc Surg 2010;139:1316-1324.
37. Myers TJ, Bolmers M, Gregoric ID, Kar B, Frazier OH. Assessment of arterial blood pressure during support with an axial flow left ventricular assist device. J Heart Lung Transplant 2009;28:423-427.
38. John R, Mantz K, Eckman P, Rose A, May-Newman K. Aortic valve pathophysiology during left ventricular assist device support. J Heart Lung Transplant 2010; 29:1321-1329.
39. Pak SW, Uriel N, Takayama H, Cappleman S, Song R, Colombo PC, Charles S, Mancini D, Gillam L, Naka Y, Jorde UP. Prevalence of de novo aortic insufficiency during long-term support with left ventricular assist devices. J Heart Lung Transplant 2010;29:1172-1176.
40. Cowger J, Pagani FD, Haft JW, Romano MA, Aaronson KD, Kolias TJ. The development of aortic insufficiency in left ventricular assist device-supported patients. Circ Heart Fail 2010;3:668-674.
41. Cohn WE, Demirozu ZT, Frazier OH. Surgical closure of left ventricular outflow tract after left ventricular assist device implantation in patients with aortic valve pathology. J Heart Lung Transplant 2011;30:59-63.
42. Lick SD, Kollar AC, Conti VR. 'Snake-jaw' graft for aortic valve exposure during LVAD implant. J Card Surg 2010;25:747-748.
43. Hatano M, Kinugawa K, Shiga T, Kato N, Endo M, Hisagi M, Nishimura T, Yao A, Hirata Y, Kyo S, Ono M, Nagai R. Less frequent opening of the aortic valve and a continuous flow pump are risk factors for postoperative onset of aortic insufficiency in patients with a left ventricular assist device. Circ J 2011;75:1147-1155.
44. Martina J, de Jonge N, Sukkel E, Lahpor J. Left ventricular assist device-related systolic aortic regurgitation. Circulation 2011;124:487-488.
45. Oswald H, Schultz-Wildelau C, Gardiwal A, Lüsebrink U, König T, Meyer A, Duncker D, Pichlmaier MA, Klein G, Strüber M. Implantable defibrillator therapy for ventricular tachyarrhythmia in left ventricular assist device patients. Eur J Heart Fail 2010;12:593-599.
46. Kirkels J.H., de Jonge N, Lahpor J.R. Assist devices in the new decade: from technical developments to political decisions. Eur J Heart Fail 2010;12:217-218.